Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 351
- +22 vs. Q1 2022
- Shares held
- 124.6M
- +27.5K (0.0%) vs. Q1 2022
- Total value
- $4.61B
- −$315.6K (0.0%) vs. Q1 2022
- New holders
- 53
- 89 more added
- Sold out
- 31
- 130 more reduced
4 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sectoral Asset Management Inc | 4,450 | $165.0K | 0.03% | +4,450 | New |
| Group One Trading, L.P. | 4,654 | $172.0K | 0.00% | +4,654 | New |
| Mercer Global Advisors Inc | 5,396 | $200.0K | 0.00% | +5,396 | New |
| Seven Eight Capital, LP | 5,457 | $202.0K | 0.08% | −10,339−65.5% | Reduced |
| Gsa Capital Partners LLP | 5,475 | $203.0K | 0.03% | +5,475 | New |
| Allspring Global Investments Holdings, LLC | 5,519 | $204.0K | 0.00% | −81,766−93.7% | Reduced |
| M&T Bank Corp | 5,501 | $204.0K | 0.00% | +5,501 | New |
| Berkshire Asset Management LLC | 5,596 | $207.0K | 0.01% | −4,143−42.5% | Reduced |
| Lazard Asset Management LLC | 5,625 | $207.0K | 0.00% | +568+11.2% | Added |
| First Republic Investment Management, Inc. | 6,016 | $223.0K | 0.00% | −90−1.5% | Reduced |
| JustInvest LLC | 6,083 | $225.0K | 0.01% | +487+8.7% | Added |
| Parametrica Management Ltd | 6,165 | $228.0K | 0.25% | +6,165 | New |
| Walleye Capital LLC | 6,369 | $236.0K | 0.01% | +6,369 | New |
| First Foundation Advisors | 6,412 | $237.0K | 0.01% | −22,718−78.0% | Reduced |
| Two Sigma Securities, LLC | 6,573 | $243.0K | 0.04% | +6,573 | New |
| Old Mission Capital LLC | 6,582 | $244.0K | 0.01% | +6,582 | New |
| Great West Life Assurance Co | 6,720 | $248.0K | 0.00% | +115+1.7% | Added |
| Baird Financial Group, Inc. | 6,897 | $255.0K | 0.00% | −3,396−33.0% | Reduced |
| Aristides Capital LLC | 6,891 | $255.0K | 0.20% | 00.0% | Unchanged |
| Virtus ETF Advisers LLC | 6,925 | $256.0K | 0.09% | −5,371−43.7% | Reduced |
| Northwestern Mutual Wealth Management Co | 6,979 | $258.0K | 0.00% | +4,716+208.4% | Added |
| Stonegate Investment Group, LLC | 7,055 | $261.0K | 0.01% | +681+10.7% | Added |
| Tanaka Capital Management Inc | 7,112 | $263.0K | 0.86% | −1,435−16.8% | Reduced |
| NewEdge Wealth, LLC | 7,315 | $271.0K | 0.01% | +7,315 | New |
| American Century Companies Inc | 7,355 | $272.0K | 0.00% | +1,761+31.5% | Added |
| Utah Retirement Systems | 7,400 | $274.0K | 0.00% | 00.0% | Unchanged |
| Commerce Bank | 7,431 | $275.0K | 0.00% | −567−7.1% | Reduced |
| Martingale Asset Management L P | 7,405 | $275.0K | 0.01% | 00.0% | Unchanged |
| Prelude Capital Management, LLC | 7,428 | $275.0K | 0.01% | +7,428 | New |
| IFP Advisors, Inc | 5,789 | $279.0K | 0.01% | −3,373−36.8% | Reduced |
| Toroso Investments, LLC | 7,607 | $282.0K | 0.01% | +2,030+36.4% | Added |
| Northeast Financial Consultants Inc | 7,740 | $287.0K | 0.02% | 00.0% | Unchanged |
| Horizon Kinetics Asset Management LLC | 8,000 | $296.0K | 0.01% | 00.0% | Unchanged |
| Independent Financial Group, LLC | 8,125 | $300.8K | 0.03% | −365−4.3% | Reduced |
| MetLife Investment Management | 8,287 | $306.8K | 0.00% | −292−3.4% | Reduced |
| Corton Capital Inc. | 8,398 | $311.0K | 0.29% | −411−4.7% | Reduced |
| National Asset Management, Inc. | 8,402 | $312.0K | 0.01% | −696−7.7% | Reduced |
| Brandywine Managers, LLC | 8,460 | $313.0K | 0.77% | 00.0% | Unchanged |
| Nicollet Investment Management, Inc. | 8,442 | $313.0K | 0.17% | +173+2.1% | Added |
| Bayesian Capital Management, LP | 9,063 | $336.0K | 0.06% | +9,063 | New |
| Delphia (USA) Inc. | 9,311 | $345.0K | 0.24% | +3,095+49.8% | Added |
| HighTower Advisors, LLC | 9,488 | $349.0K | 0.00% | +376+4.1% | Added |
| Verition Fund Management LLC | 9,531 | $353.0K | 0.01% | +9,531 | New |
| Wrapmanager Inc | 9,551 | $354.0K | 0.11% | −163−1.7% | Reduced |
| Brown Advisory Inc | 9,630 | $357.0K | 0.00% | +9,630 | New |
| Bridgewater Associates, LP | 9,779 | $362.0K | 0.00% | +2,578+35.8% | Added |
| Rockefeller Capital Management L.P. | 9,851 | $363.0K | 0.00% | −1,405−12.5% | Reduced |
| Maryland State Retirement & Pension System | 9,956 | $369.0K | 0.01% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 9,982 | $370.0K | 0.00% | +320+3.3% | Added |
| Waddell & Associates, LLC | 10,042 | $372.0K | 0.08% | +10,042 | New |
| SEI Investments Co | 10,626 | $392.0K | 0.00% | −392−3.6% | Reduced |
| Oppenheimer Asset Management Inc. | 10,903 | $403.0K | 0.01% | −92−0.8% | Reduced |
| Neuberger Berman Group LLC | 11,086 | $410.0K | 0.00% | +11,086 | New |
| Cambridge Investment Research Advisors, Inc. | 11,122 | $412.0K | 0.00% | +655+6.3% | Added |
| Hanseatic Management Services Inc | 11,222 | $415.0K | 0.94% | +11,222 | New |
| Plancorp, LLC | 11,235 | $416.0K | 0.03% | +23+0.2% | Added |
| Campbell & CO Investment Adviser LLC | 11,299 | $418.0K | 0.11% | +11,299 | New |
| Ameriprise Financial Inc | 11,384 | $421.0K | 0.00% | −1,298−10.2% | Reduced |
| Stephens Inc | 11,644 | $431.0K | 0.01% | −908−7.2% | Reduced |
| Man Group plc | – | $442.0K | 0.00% | – | New |
| Strategic Wealth Advisors Group, LLC | 12,090 | $445.0K | 0.02% | −9,394−43.7% | Reduced |
| Arden Trust Co | 12,192 | $451.0K | 0.10% | −126−1.0% | Reduced |
| Teza Capital Management LLC | 12,225 | $453.0K | 0.17% | +4,707+62.6% | Added |
| Comerica Bank | 11,684 | $459.0K | 0.00% | −71−0.6% | Reduced |
| E Fund Management Co., Ltd. | 12,597 | $466.0K | 0.04% | +4,263+51.2% | Added |
| Creative Planning | 12,729 | $471.0K | 0.00% | −29−0.2% | Reduced |
| Point72 Asset Management, L.P. | 13,185 | $488.0K | 0.00% | +13,185 | New |
| Lincoln National Corp | 13,261 | $491.0K | 0.01% | 00.0% | Unchanged |
| ProShare Advisors LLC | 13,367 | $495.0K | 0.00% | −4,534−25.3% | Reduced |
| Victory Capital Management Inc | 13,546 | $501.0K | 0.00% | +1,721+14.6% | Added |
| North Star Asset Management Inc | 13,680 | $506.0K | 0.03% | 00.0% | Unchanged |
| Shell Asset Management Co | 14,216 | $526.0K | 0.02% | +3,194+29.0% | Added |
| Vontobel Holding Ltd. | 14,210 | $534.0K | 0.01% | −505−3.4% | Reduced |
| Oppenheimer & Co Inc | 14,560 | $539.0K | 0.01% | −2,000−12.1% | Reduced |
| Blair William & Co | 14,607 | $541.0K | 0.00% | −121−0.8% | Reduced |
| Xponance, Inc. | 15,418 | $571.0K | 0.01% | +520+3.5% | Added |
| Castle Rock Wealth Management, LLC | 15,593 | $573.0K | 0.29% | 00.0% | Unchanged |
| Natixis Advisors, L.P. | 15,830 | $586.0K | 0.00% | −31−0.2% | Reduced |
| Fox Run Management, L.L.C. | 15,947 | $590.0K | 0.29% | +6,893+76.1% | Added |
| Profund Advisors LLC | 16,203 | $600.0K | 0.04% | −1,389−7.9% | Reduced |
| Engineers Gate Manager LP | 16,703 | $618.0K | 0.02% | +6,835+69.3% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 16,734 | $619.0K | 0.00% | −1,514−8.3% | Reduced |
| Cetera Advisor Networks LLC | 17,276 | $640.0K | 0.01% | +1,295+8.1% | Added |
| US Bancorp | 17,323 | $641.0K | 0.00% | −4,135−19.3% | Reduced |
| Advisor Group Holdings, Inc. | 17,424 | $646.0K | 0.00% | −2,142−10.9% | Reduced |
| AtonRa Partners | 18,146 | $672.0K | 0.62% | +18,146 | New |
| Dynamic Technology Lab Private Ltd | 18,310 | $678.0K | 0.08% | +18,310 | New |
| Handelsbanken Fonder AB | 18,511 | $685.0K | 0.00% | +4,800+35.0% | Added |
| Public Employees Retirement Association of Colorado | 19,604 | $726.0K | 0.00% | 00.0% | Unchanged |
| Teacher Retirement System of Texas | 20,265 | $750.0K | 0.01% | −5,947−22.7% | Reduced |
| Global Retirement Partners, LLC | 20,431 | $756.0K | 0.06% | +90+0.4% | Added |
| Ziegler Capital Management, LLC | 20,779 | $769.0K | 0.03% | +20,779 | New |
| Skandinaviska Enskilda Banken AB (publ) | 20,878 | $773.0K | 0.01% | 00.0% | Unchanged |
| Truist Financial Corp | 22,364 | $828.0K | 0.00% | −8,906−28.5% | Reduced |
| Storebrand Asset Management AS | 22,462 | $831.5K | 0.00% | 00.0% | Unchanged |
| Allianz Asset Management GmbH | 22,497 | $833.0K | 0.00% | −59,333−72.5% | Reduced |
| Virtu Financial LLC | 22,794 | $844.0K | 0.07% | +22,794 | New |
| Kestra Advisory Services, LLC | 22,831 | $845.0K | 0.01% | −786−3.3% | Reduced |
| Janus Henderson Group PLC | 23,207 | $858.0K | 0.00% | −2,516−9.8% | Reduced |
| Vestmark Advisory Solutions, Inc. | 23,595 | $874.0K | 0.05% | +4,434+23.1% | Added |