Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2021
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 326
- −9 vs. Q2 2021
- Shares held
- 121.7M
- −2.53M (−2.0%) vs. Q2 2021
- Total value
- $4.08B
- −$872.0M (−17.6%) vs. Q2 2021
- New holders
- 38
- 108 more added
- Sold out
- 47
- 103 more reduced
3 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2021
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Fifth Third Bancorp | 2,626 | $88.0K | 0.00% | +72+2.8% | Added |
| American International Group, Inc. | 2,660 | $89.0K | 0.00% | −208−7.3% | Reduced |
| Advisors Asset Management, Inc. | 3,164 | $106.0K | 0.00% | −15−0.5% | Reduced |
| Carolinas Wealth Consulting LLC | 3,187 | $107.0K | 0.02% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 3,356 | $113.0K | 0.00% | +244+7.8% | Added |
| Semmax Financial Advisors Inc. | 3,431 | $115.0K | 0.04% | −355−9.4% | Reduced |
| Caldwell Trust Co | 4,000 | $134.2K | 0.02% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 4,253 | $143.0K | 0.00% | +163+4.0% | Added |
| Agf Investments Inc. | 4,800 | $161.0K | 0.00% | −438−8.4% | Reduced |
| Geneos Wealth Management Inc. | 4,838 | $162.0K | 0.01% | +134+2.8% | Added |
| Leonteq Securities AG | 5,479 | $183.8K | 0.01% | +2,282+71.4% | Added |
| Global Retirement Partners, LLC | 5,784 | $194.0K | 0.02% | +471+8.9% | Added |
| Assenagon Asset Management S.A. | 6,022 | $202.0K | 0.00% | +6,022 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 6,244 | $209.0K | 0.00% | −124−1.9% | Reduced |
| Nisa Investment Advisors, LLC | 6,249 | $210.0K | 0.00% | −1,534−19.7% | Reduced |
| Prudential Financial Inc | 5,763 | $214.0K | 0.00% | +611+11.9% | Added |
| Mirae Asset Global Investments Co., Ltd. | 6,599 | $221.0K | 0.00% | +6,599 | New |
| Mitchell & Pahl Private Wealth, LLC | 6,888 | $231.0K | 0.17% | −48−0.7% | Reduced |
| Great West Life Assurance Co | 6,922 | $234.0K | 0.00% | −26,244−79.1% | Reduced |
| Fox Run Management, L.L.C. | 7,341 | $246.0K | 0.15% | +7,341 | New |
| FDx Advisors, Inc. | 7,507 | $252.0K | 0.01% | −869−10.4% | Reduced |
| Northeast Financial Consultants Inc | 7,740 | $260.0K | 0.02% | 00.0% | Unchanged |
| Horizon Kinetics Asset Management LLC | 8,000 | $268.0K | 0.01% | 00.0% | Unchanged |
| Kennedy Capital Management, Inc. | 8,064 | $270.0K | 0.01% | −265−3.2% | Reduced |
| ExodusPoint Capital Management, LP | 8,173 | $274.0K | 0.00% | +8,173 | New |
| Brandywine Managers, LLC | 8,460 | $284.0K | 0.30% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 8,799 | $294.0K | 0.00% | −548−5.9% | Reduced |
| Metropolitan Life Insurance Co | 8,880 | $297.8K | 0.00% | −293−3.2% | Reduced |
| KBC Group NV | 8,912 | $299.0K | 0.00% | −2,899−24.5% | Reduced |
| Baird Financial Group, Inc. | 8,949 | $300.0K | 0.00% | +1,553+21.0% | Added |
| Regions Financial Corp | 9,423 | $316.0K | 0.00% | 00.0% | Unchanged |
| Walleye Trading LLC | 9,619 | $323.0K | 0.01% | +9,619 | New |
| Bard Financial Services, Inc. | 9,725 | $326.0K | 0.03% | +9,725 | New |
| Mackenzie Financial Corp | 9,783 | $328.0K | 0.00% | 00.0% | Unchanged |
| HighTower Advisors, LLC | 9,857 | $334.0K | 0.00% | +554+6.0% | Added |
| Maryland State Retirement & Pension System | 9,956 | $336.0K | 0.01% | 00.0% | Unchanged |
| Wrapmanager Inc | 10,324 | $346.0K | 0.09% | −259−2.4% | Reduced |
| Nicollet Investment Management, Inc. | 10,501 | $352.0K | 0.15% | −30.0% | Reduced |
| Comerica Bank | 11,830 | $360.0K | 0.00% | −3,761−24.1% | Reduced |
| Oppenheimer Asset Management Inc. | 10,882 | $365.0K | 0.01% | +165+1.5% | Added |
| Ameriprise Financial Inc | 10,899 | $366.0K | 0.00% | +974+9.8% | Added |
| Plancorp, LLC | 11,134 | $373.0K | 0.03% | +14+0.1% | Added |
| National Asset Management, Inc. | 11,018 | $379.0K | 0.01% | −188−1.7% | Reduced |
| Brookstone Capital Management | 11,397 | $382.0K | 0.01% | +11,397 | New |
| Koss-Olinger Consulting, LLC | 11,432 | $383.0K | 0.06% | +11,432 | New |
| Dynamic Technology Lab Private Ltd | 11,500 | $386.0K | 0.05% | +11,500 | New |
| Virginia Retirement Systems Et Al | 11,700 | $392.0K | 0.00% | +11,700 | New |
| HAP Trading, LLC | 11,877 | $398.0K | 0.03% | +11,877 | New |
| SEI Investments Co | 13,957 | $401.0K | 0.00% | −95−0.7% | Reduced |
| Virtus ETF Advisers LLC | 12,102 | $406.0K | 0.18% | −1,110−8.4% | Reduced |
| Bank of Nova Scotia | 12,315 | $413.0K | 0.00% | −1,220−9.0% | Reduced |
| Cetera Advisor Networks LLC | 12,552 | $421.0K | 0.01% | +4,335+52.8% | Added |
| Shell Asset Management Co | 12,603 | $423.0K | 0.01% | −566−4.3% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 12,817 | $430.0K | 0.00% | 00.0% | Unchanged |
| Cowen and Company, LLC | 12,843 | $431.0K | 0.02% | −14,865−53.6% | Reduced |
| Berkshire Asset Management LLC | 13,060 | $438.0K | 0.03% | +1,661+14.6% | Added |
| Trexquant Investment LP | 13,297 | $446.0K | 0.04% | +13,297 | New |
| Victory Capital Management Inc | 13,339 | $447.0K | 0.00% | −877−6.2% | Reduced |
| JustInvest LLC | 13,544 | $454.0K | 0.04% | +13,544 | New |
| North Star Asset Management Inc | 13,680 | $459.0K | 0.03% | −73−0.5% | Reduced |
| Janus Henderson Group PLC | 13,748 | $461.0K | 0.00% | +13,748 | New |
| Lincoln National Corp | 14,270 | $479.0K | 0.01% | −800−5.3% | Reduced |
| Blair William & Co | 14,514 | $487.0K | 0.00% | +4,226+41.1% | Added |
| Xponance, Inc. | 14,572 | $489.0K | 0.01% | −654−4.3% | Reduced |
| Creative Planning | 14,915 | $500.0K | 0.00% | +1,595+12.0% | Added |
| Optimal Asset Management, Inc. | 15,118 | $507.0K | 0.06% | 00.0% | Unchanged |
| Walleye Capital LLC | 15,470 | $519.0K | 0.02% | +15,470 | New |
| Brown Advisory Securities, LLC | 15,500 | $521.0K | 0.15% | +2,000+14.8% | Added |
| AGF Investments LLC | 15,936 | $534.0K | 0.05% | −1,353−7.8% | Reduced |
| Arden Trust Co | 16,097 | $540.0K | 0.09% | +104+0.7% | Added |
| Castle Rock Wealth Management, LLC | 15,593 | $544.0K | 0.19% | 00.0% | Unchanged |
| US Bancorp | 16,383 | $550.0K | 0.00% | +2,375+17.0% | Added |
| Tanaka Capital Management Inc | 16,661 | $559.0K | 0.80% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 16,672 | $559.0K | 0.03% | +16,672 | New |
| Emerald Advisers, LLC | 16,815 | $564.0K | 0.02% | −806−4.6% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 16,867 | $566.0K | 0.00% | −2,407−12.5% | Reduced |
| State of Wisconsin Investment Board | 17,579 | $590.0K | 0.00% | +830+5.0% | Added |
| Natixis Advisors, L.P. | 17,728 | $595.0K | 0.00% | −1,136−6.0% | Reduced |
| Alexandria Capital, LLC | 18,362 | $616.0K | 0.06% | +65+0.4% | Added |
| Advisor Group Holdings, Inc. | 18,441 | $619.0K | 0.00% | −2,462−11.8% | Reduced |
| SG3 Management, LLC | 18,500 | $620.0K | 0.22% | −53,800−74.4% | Reduced |
| Public Employees Retirement Association of Colorado | 19,604 | $658.0K | 0.00% | 00.0% | Unchanged |
| Allianz Asset Management GmbH | 19,710 | $661.0K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 19,721 | $661.0K | 0.00% | +8,472+75.3% | Added |
| Teacher Retirement System of Texas | 19,760 | $663.0K | 0.00% | +2,242+12.8% | Added |
| Campbell & CO Investment Adviser LLC | 19,896 | $667.0K | 0.22% | +19,896 | New |
| Vestmark Advisory Solutions, Inc. | 20,033 | $672.0K | 0.05% | +146+0.7% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 20,878 | $700.0K | 0.00% | −11,415−35.3% | Reduced |
| Stephens Inc | 21,141 | $709.0K | 0.01% | −4,497−17.5% | Reduced |
| Oppenheimer & Co Inc | 21,127 | $709.0K | 0.01% | −221−1.0% | Reduced |
| Grandfield & Dodd, LLC | 21,691 | $730.0K | 0.05% | +638+3.0% | Added |
| Sphera Funds Management Ltd. | 22,000 | $738.0K | 0.07% | +22,000 | New |
| Profund Advisors LLC | 22,891 | $768.0K | 0.03% | −1,167−4.9% | Reduced |
| Algert Global LLC | 23,474 | $787.0K | 0.10% | +23,474 | New |
| Handelsbanken Fonder AB | 24,411 | $819.0K | 0.00% | 00.0% | Unchanged |
| MML Investors Services, LLC | 24,614 | $826.0K | 0.01% | +1,828+8.0% | Added |
| Utah Retirement Systems | 25,309 | $849.0K | 0.01% | −1,400−5.2% | Reduced |
| Amalgamated Bank | 25,401 | $852.0K | 0.01% | −1,532−5.7% | Reduced |
| BNP Paribas Arbitrage, SA | 25,732 | $863.1K | 0.00% | +4,465+21.0% | Added |
| Eaton Vance Management | 26,874 | $885.0K | 0.00% | −200−0.7% | Reduced |