Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2021
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 338
- −24 vs. Q1 2021
- Shares held
- 124.4M
- +2.62M (+2.2%) vs. Q1 2021
- Total value
- $4.96B
- −$516.2M (−9.4%) vs. Q1 2021
- New holders
- 51
- 116 more added
- Sold out
- 75
- 103 more reduced
3 institutions that held it in Q1 2021 haven't filed for Q2 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2021
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Dimensional Fund Advisors LP | 410,217 | $16.4M | 0.01% | −47,064−10.3% | Reduced |
| Eversept Partners, LP | 442,000 | $17.6M | 1.63% | +442,000 | New |
| Altrinsic Global Advisors LLC | 456,226 | $18.2M | 0.55% | +15,172+3.4% | Added |
| Royal Bank of Canada | 484,966 | $19.3M | 0.01% | +325,352+203.8% | Added |
| Nikko Asset Management Americas, Inc. | 508,374 | $20.4M | 0.08% | +10,118+2.0% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 524,326 | $20.9M | 0.01% | −376,975−41.8% | Reduced |
| Two Sigma Advisers, LP | 525,811 | $21.0M | 0.06% | −188,600−26.4% | Reduced |
| Morgan Stanley | 527,609 | $21.0M | 0.00% | −40,058−7.1% | Reduced |
| Bank of New York Mellon Corp | 540,529 | $21.6M | 0.00% | −4,569−0.8% | Reduced |
| Pinnacle Associates Ltd | 541,342 | $21.6M | 0.39% | +28,218+5.5% | Added |
| Citadel Advisors LLC | 545,480 | $21.8M | 0.02% | +375,631+221.2% | Added |
| Candriam Luxembourg S.C.A. | 552,566 | $22.0M | 0.15% | +305,612+123.8% | Added |
| Northern Trust Corp | 671,573 | $26.8M | 0.00% | −169,572−20.2% | Reduced |
| Goldman Sachs Group Inc | 679,429 | $27.1M | 0.01% | −65,481−8.8% | Reduced |
| Charles Schwab Investment Management Inc | 713,960 | $28.5M | 0.01% | +17,464+2.5% | Added |
| Bank of America Corp | 717,497 | $28.6M | 0.00% | +25,914+3.7% | Added |
| Nuveen Asset Management, LLC | 723,101 | $28.8M | 0.01% | −226,136−23.8% | Reduced |
| Renaissance Technologies LLC | 776,414 | $31.0M | 0.04% | +189,000+32.2% | Added |
| Millennium Management LLC | 795,842 | $31.7M | 0.04% | +164,578+26.1% | Added |
| Wells Fargo & Company | 841,431 | $33.6M | 0.01% | −315,568−27.3% | Reduced |
| Norges Bank | 896,289 | $35.8M | 0.01% | +88,801+11.0% | Added |
| Woodline Partners LP | 963,788 | $38.4M | 0.72% | +487,897+102.5% | Added |
| Point72 Asset Management, L.P. | 976,900 | $39.0M | 0.19% | +976,900 | New |
| Jacobs Levy Equity Management, Inc | 1,084,422 | $43.3M | 0.29% | +921,476+565.5% | Added |
| Swedbank AB | 1,117,275 | $44.6M | 0.08% | −3,792−0.3% | Reduced |
| Rockefeller Capital Management L.P. | 1,324,611 | $52.8M | 0.30% | +590,632+80.5% | Added |
| First Trust Advisors LP | 1,522,449 | $60.7M | 0.07% | +354,640+30.4% | Added |
| Geode Capital Management, LLC | 1,762,540 | $70.3M | 0.01% | +33,394+1.9% | Added |
| Camber Capital Management LP | 2,000,000 | $79.8M | 3.13% | +1,000,000+100.0% | Added |
| JPMorgan Chase & Co | 2,275,706 | $90.8M | 0.01% | +312,483+15.9% | Added |
| State Street Corp | 3,230,951 | $128.9M | 0.01% | −178,620−5.2% | Reduced |
| Clearbridge Investments, LLC | 6,815,601 | $271.9M | 0.19% | −587,366−7.9% | Reduced |
| BlackRock Inc. | 8,179,666 | $326.3M | 0.01% | −1,628,896−16.6% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 8,907,733 | $355.3M | 0.66% | +3,765,462+73.2% | Added |
| Bellevue Group AG | 9,930,245 | $396.1M | 3.87% | +946,011+10.5% | Added |
| Price T Rowe Associates Inc | 12,258,827 | $489.0M | 0.05% | −321,229−2.6% | Reduced |
| Vanguard Group Inc | 12,655,829 | $504.8M | 0.01% | +51,680+0.4% | Added |
| FMR LLC | 21,144,455 | $843.5M | 0.07% | +50,559+0.2% | Added |
| BVF Inc | 0 | $0 | 0.00% | −1,364,461−100.0% | Sold out |
| Farallon Capital Management, L.L.C. | 0 | $0 | 0.00% | −630,500−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −427,990−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −319,539−100.0% | Sold out |
| AXA S.A. | 0 | $0 | 0.00% | −192,629−100.0% | Sold out |
| Sphera Funds Management Ltd. | 0 | $0 | 0.00% | −145,476−100.0% | Sold out |
| Edmond de Rothschild Holding S.A. | 0 | $0 | 0.00% | −86,250−100.0% | Sold out |
| Janus Henderson Group PLC | 0 | $0 | 0.00% | −76,644−100.0% | Sold out |
| Asset Management One Co.,Ltd. | 0 | $0 | 0.00% | −60,617−100.0% | Sold out |
| Andra AP-fonden | 0 | $0 | 0.00% | −59,700−100.0% | Sold out |
| Fjarde Ap-Fonden /Fourth Swedish National Pension Fund | 0 | $0 | 0.00% | −57,500−100.0% | Sold out |
| DnB Asset Management AS | 0 | $0 | 0.00% | −56,658−100.0% | Sold out |
| Connor, Clark & Lunn Investment Management Ltd. | 0 | $0 | 0.00% | −51,579−100.0% | Sold out |
| Canada Pension Plan Investment Board | 0 | $0 | 0.00% | −36,762−100.0% | Sold out |
| AMP Capital Investors Ltd | 0 | $0 | 0.00% | −31,333−100.0% | Sold out |
| Korea Investment CORP | 0 | $0 | 0.00% | −29,900−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −29,160−100.0% | Sold out |
| Gulf International Bank (UK) Ltd | 0 | $0 | 0.00% | −23,940−100.0% | Sold out |
| Twinbeech Capital LP | 0 | $0 | 0.00% | −22,750−100.0% | Sold out |
| Gyon Technologies Capital Management, LP | 0 | $0 | 0.00% | −22,376−100.0% | Sold out |
| British Columbia Investment Management Corp | 0 | $0 | 0.00% | −21,768−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −21,101−100.0% | Sold out |
| AtonRa Partners | 0 | $0 | 0.00% | −20,146−100.0% | Sold out |
| Toronto Dominion Bank | 0 | $0 | 0.00% | −17,977−100.0% | Sold out |
| IFM Investors Pty Ltd | 0 | $0 | 0.00% | −15,830−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −14,360−100.0% | Sold out |
| Nissay Asset Management Corp | 0 | $0 | 0.00% | −14,204−100.0% | Sold out |
| NN Investment Partners Holdings N.V. | 0 | $0 | 0.00% | −14,118−100.0% | Sold out |
| Migdal Insurance & Financial Holdings Ltd. | 0 | $0 | 0.00% | −13,305−100.0% | Sold out |
| Ritholtz Wealth Management | 0 | $0 | 0.00% | −12,501−100.0% | Sold out |
| Voya Financial Advisors, Inc. | 0 | $0 | 0.00% | −12,433−100.0% | Sold out |
| Reynders McVeigh Capital Management, LLC | 0 | $0 | 0.00% | −12,174−100.0% | Sold out |
| Echo Street Capital Management LLC | 0 | $0 | 0.00% | −10,613−100.0% | Sold out |
| Westpac Banking Corp | 0 | $0 | 0.00% | −10,594−100.0% | Sold out |
| Quantitative Investment Management, LLC | 0 | $0 | 0.00% | −9,931−100.0% | Sold out |
| CSS LLC | 0 | $0 | 0.00% | −9,605−100.0% | Sold out |
| NewEdge Wealth, LLC | 0 | $0 | 0.00% | −8,224−100.0% | Sold out |
| Magnetar Financial LLC | 0 | $0 | 0.00% | −7,865−100.0% | Sold out |
| Mirae Asset Global Investments Co., Ltd. | 0 | $0 | 0.00% | −7,772−100.0% | Sold out |
| Meiji Yasuda Asset Management Co Ltd. | 0 | $0 | 0.00% | −7,730−100.0% | Sold out |
| Keybank National Association | 0 | $0 | 0.00% | −7,500−100.0% | Sold out |
| Sumitomo Mitsui DS Asset Management Company, Ltd | 0 | $0 | 0.00% | −7,251−100.0% | Sold out |
| ETF Managers Group, LLC | 0 | $0 | 0.00% | −6,975−100.0% | Sold out |
| Bridgefront Capital, LLC | 0 | $0 | 0.00% | −6,798−100.0% | Sold out |
| TD Ameritrade Investment Management, LLC | 0 | $0 | 0.00% | −5,000−100.0% | Sold out |
| Illinois Municipal Retirement Fund | 0 | $0 | 0.00% | −6,118−100.0% | Sold out |
| Argent Trust Co | 0 | $0 | 0.00% | −5,736−100.0% | Sold out |
| Cresset Asset Management, LLC | 0 | $0 | 0.00% | −5,728−100.0% | Sold out |
| Standard Life Aberdeen plc | 0 | $0 | 0.00% | −5,197−100.0% | Sold out |
| Nordea Investment Management AB | 0 | $0 | 0.00% | −5,156−100.0% | Sold out |
| Robeco Institutional Asset Management B.V. | 0 | $0 | 0.00% | −5,038−100.0% | Sold out |
| IBM Retirement Fund | 0 | $0 | 0.00% | −4,462−100.0% | Sold out |
| E. Ohman J:or Asset Management AB | 0 | $0 | 0.00% | −3,400−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −2,378−100.0% | Sold out |
| First Quadrant L P | 0 | $0 | 0.00% | −2,082−100.0% | Sold out |
| Livforsakringsbolaget Skandia, Omsesidigt | 0 | $0 | 0.00% | −1,500−100.0% | Sold out |
| Pacer Advisors, Inc. | 0 | $0 | 0.00% | −1,471−100.0% | Sold out |
| STRS Ohio | 0 | $0 | 0.00% | −1,454−100.0% | Sold out |
| Federation des caisses Desjardins du Quebec | 0 | $0 | 0.00% | −1,271−100.0% | Sold out |
| Archer Investment Corp | 0 | $0 | 0.00% | −917−100.0% | Sold out |
| Sowell Financial Services LLC | 0 | $0 | 0.00% | −1,059−100.0% | Sold out |
| Allred Capital Management, LLC | 0 | $0 | 0.00% | −771−100.0% | Sold out |