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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q1 2021

Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
365
No complete 13F data for Q4 2020
Shares held
123.5M
No complete 13F data for Q4 2020
Total value
$5.55B
No complete 13F data for Q4 2020

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2021: 365 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ1 2021: $5.55B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q1 2021

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc.

Livermore's 13F data starts with Q1 2021, so Q1 2021 has no change from the previous quarter.

Institutions holding IONS in Q1 2021
InstitutionSharesValue% of portfolioChange in sharesAction
MML Investors Services, LLC19,896$895.0K0.01%––
SG3 Management, LLC20,000$899.0K0.29%––
Jefferies Group LLC20,127$904.9K0.02%––
AtonRa Partners20,146$906.0K0.40%––
Grandfield & Dodd, LLC20,353$920.0K0.07%––
Natixis Advisors, L.P.20,604$926.0K0.00%––
Tanaka Capital Management Inc20,611$927.0K1.18%––
Schonfeld Strategic Advisors LLC21,101$948.0K0.01%––
Zurcher Kantonalbank (Zurich Cantonalbank)21,221$954.0K0.01%––
Truist Financial Corp21,664$974.0K0.00%––
British Columbia Investment Management Corp21,768$979.0K0.01%––
ProShare Advisors LLC22,135$995.0K0.00%––
Gyon Technologies Capital Management, LP22,376$1.01M0.44%––
Twinbeech Capital LP22,750$1.02M0.15%––
Kestra Advisory Services, LLC22,950$1.03M0.01%––
Handelsbanken Fonder AB23,011$1.03M0.01%––
Nomura Asset Management Co Ltd23,300$1.05M0.01%––
Gulf International Bank (UK) Ltd23,940$1.08M0.01%––
Profund Advisors LLC24,797$1.11M0.04%––
Utah Retirement Systems25,109$1.13M0.02%––
Stephens Inc25,156$1.13M0.02%––
Victory Capital Management Inc26,250$1.18M0.00%––
Eaton Vance Management26,470$1.19M0.00%––
Vestmark Advisory Solutions, Inc.26,509$1.19M0.11%––
Teacher Retirement System of Texas27,956$1.26M0.01%––
BNP Paribas Arbitrage, SA28,640$1.29M0.00%––
Group One Trading, L.P.28,911$1.30M0.03%––
UBS Group AG29,062$1.31M0.00%––
Engineers Gate Manager LP29,160$1.31M0.06%––
Korea Investment CORP29,900$1.34M0.00%––
First Foundation Advisors30,063$1.35M0.06%––
Macquarie Group Ltd30,457$1.37M0.00%––
SEI Investments Co27,462$1.38M0.00%––
Voya Investment Management LLC30,711$1.38M0.00%––
Russell Investments Group, Ltd.30,931$1.39M0.00%––
AMP Capital Investors Ltd31,333$1.41M0.01%––
Employees Retirement System of Texas32,409$1.46M0.02%––
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.32,510$1.46M0.01%––
Jane Street Group, LLC32,863$1.48M0.00%––
Seeyond33,701$1.51M0.15%––
Erste Asset Management GmbH34,500$1.54M0.04%––
Allianz Asset Management GmbH34,844$1.57M0.00%––
Raymond James Financial Services Advisors, Inc.35,529$1.60M0.00%––
Canada Pension Plan Investment Board36,762$1.65M0.00%––
Janney Montgomery Scott LLC36,812$1.66M0.01%––
Storebrand Asset Management AS37,353$1.68M0.01%––
Gateway Investment Advisers LLC37,600$1.69M0.02%––
Arizona State Retirement System38,299$1.72M0.02%––
NJ State Employees Deferred Compensation Plan42,000$1.89M0.27%––
Capital Counsel LLC42,080$1.89M0.11%––
Creative Planning44,179$1.99M0.00%––
Principal Financial Group Inc44,411$2.00M0.00%––
SG Americas Securities, LLC45,808$2.06M0.01%––
Shell Asset Management Co46,133$2.07M0.04%––
Treasurer of the State of North Carolina47,917$2.15M0.01%––
Pictet Asset Management Ltd49,000$2.20M0.00%––
Nisa Investment Advisors, LLC49,825$2.24M0.01%––
Connor, Clark & Lunn Investment Management Ltd.51,579$2.32M0.01%––
Skandinaviska Enskilda Banken AB (publ)54,493$2.45M0.02%––
Sabby Management, LLC54,688$2.46M1.81%––
Susquehanna Fundamental Investments, LLC54,804$2.46M0.04%––
LPL Financial LLC55,283$2.49M0.00%––
DnB Asset Management AS56,658$2.55M0.02%––
Great West Life Assurance Co57,476$2.57M0.01%––
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund57,500$2.58M0.02%––
Andra AP-fonden59,700$2.68M0.06%––
Asset Management One Co.,Ltd.60,617$2.73M0.01%––
Rafferty Asset Management, LLC62,884$2.83M0.02%––
Public Employees Retirement System of Ohio69,385$3.12M0.01%––
PFS Investments Inc.70,504$3.17M0.08%––
Guggenheim Capital LLC71,392$3.21M0.02%––
State of Wisconsin Investment Board72,205$3.25M0.01%––
Rhenman & Partners Asset Management AB75,000$3.37M0.24%––
Janus Henderson Group PLC76,644$3.45M0.00%––
Alliancebernstein L.P.77,300$3.48M0.00%––
Mitsubishi UFJ Trust & Banking Corp79,951$3.60M0.01%––
Amundi Asset Management US, Inc.82,126$3.69M0.00%––
Envestnet Asset Management Inc82,320$3.70M0.00%––
State of New Jersey Common Pension Fund D84,923$3.82M0.01%––
Edmond de Rothschild Holding S.A.86,250$3.88M0.11%––
Susquehanna International Group, LLP88,271$3.97M0.01%––
Barclays PLC98,771$4.44M0.00%––
Parkman Healthcare Partners LLC105,797$4.76M1.15%––
Wolverine Trading, LLC109,611$4.90M0.09%––
DekaBank Deutsche Girozentrale117,395$5.24M0.02%––
Thrivent Financial for Lutherans121,313$5.45M0.01%––
Majedie Asset Management Ltd121,699$5.47M0.40%––
Davenport & Co LLC124,738$5.61M0.05%––
Hudson Bay Capital Management LP130,400$5.86M0.08%––
Credit Suisse AG132,994$5.98M0.00%––
Rhumbline Advisers144,406$6.49M0.01%––
Sphera Funds Management Ltd.145,476$6.54M0.60%––
BLB&B Advisors, LLC156,620$7.04M0.55%––
Royal Bank of Canada159,614$7.18M0.00%––
Deutsche Bank AG160,567$7.22M0.00%––
Jacobs Levy Equity Management, Inc162,946$7.33M0.06%––
Sonora Investment Management, LLC163,923$7.37M0.58%––
State Board of Administration of Florida Retirement System168,973$7.60M0.02%––
Citadel Advisors LLC169,849$7.64M0.01%––
Van Eck Associates Corp169,992$7.64M0.02%––