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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q1 2021

Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
365
No complete 13F data for Q4 2020
Shares held
123.5M
No complete 13F data for Q4 2020
Total value
$5.55B
No complete 13F data for Q4 2020

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2021: 365 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ1 2021: $5.55B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q1 2021

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc.

Livermore's 13F data starts with Q1 2021, so Q1 2021 has no change from the previous quarter.

Institutions holding IONS in Q1 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Spire Wealth Management2,504$108.0K0.00%––
Banque Cantonale Vaudoise2,800$126.0K0.01%––
NEXT Financial Group, Inc2,817$127.0K0.01%––
Parallel Advisors, LLC2,962$133.0K0.01%––
Advisors Asset Management, Inc.3,208$144.2K0.00%––
E. Ohman J:or Asset Management AB3,400$152.9K0.01%––
Caldwell Trust Co4,000$179.8K0.03%––
Semmax Financial Advisors Inc.4,028$181.0K0.06%––
Credit Agricole S A4,210$189.0K0.01%––
IBM Retirement Fund4,462$201.0K0.01%––
Global Retirement Partners, LLC4,611$207.0K0.02%––
Geneos Wealth Management Inc.5,127$219.0K0.01%––
Robeco Institutional Asset Management B.V.5,038$227.0K0.00%––
Buckingham Strategic Wealth, LLC5,078$228.0K0.01%––
CIBC Asset Management Inc5,140$231.0K0.00%––
Nordea Investment Management AB5,156$231.0K0.00%––
Standard Life Aberdeen plc5,197$234.0K0.00%––
Brown Advisory Securities, LLC5,475$246.0K0.04%––
Natixis5,659$254.0K0.00%––
Icon Wealth Partners, LLC5,671$255.0K0.03%––
Argent Trust Co5,736$258.0K0.02%––
Cresset Asset Management, LLC5,728$258.0K0.00%––
Daiwa Securities Group Inc.5,776$260.0K0.00%––
ProVise Management Group, LLC5,804$261.0K0.03%––
Metropolitan Life Insurance Co6,015$270.4K0.00%––
Illinois Municipal Retirement Fund6,118$275.0K0.01%––
TD Ameritrade Investment Management, LLC5,000$283.0K0.00%––
Commerce Bank6,476$291.0K0.00%––
Xponance, Inc.6,803$306.0K0.01%––
Bridgefront Capital, LLC6,798$306.0K0.10%––
ETF Managers Group, LLC6,975$312.0K0.01%––
Mitchell & Pahl Private Wealth, LLC7,005$315.0K0.24%––
Baird Financial Group, Inc.7,027$316.0K0.00%––
Cowen and Company, LLC7,081$318.0K0.02%––
Brandywine Managers, LLC7,085$319.0K0.42%––
Hussman Strategic Advisors, Inc.7,200$324.0K0.07%––
Wealthcare Advisory Partners LLC7,209$324.0K0.02%––
Sumitomo Mitsui DS Asset Management Company, Ltd7,251$326.0K0.01%––
Steward Partners Investment Advisory, LLC7,342$330.1K0.01%––
Keybank National Association7,500$337.0K0.00%––
FDx Advisors, Inc.7,718$347.0K0.01%––
Meiji Yasuda Asset Management Co Ltd.7,730$348.0K0.03%––
Northeast Financial Consultants Inc7,740$348.0K0.03%––
Mirae Asset Global Investments Co., Ltd.7,772$350.0K0.00%––
Magnetar Financial LLC7,865$354.0K0.00%––
Kennedy Capital Management, Inc.8,008$360.0K0.01%––
Horizon Kinetics Asset Management LLC8,000$360.0K0.01%––
D. E. Shaw & Co., Inc.8,106$364.0K0.00%––
Carolinas Wealth Consulting LLC8,187$368.0K0.09%––
NewEdge Wealth, LLC8,224$370.0K0.04%––
USS Investment Management Ltd8,363$376.0K0.00%––
The PNC Financial Services Group, Inc.9,358$420.0K0.00%––
HighTower Advisors, LLC9,519$426.0K0.00%––
Prudential Financial Inc9,518$428.0K0.00%––
Fifth Third Bancorp9,558$430.0K0.00%––
CSS LLC9,605$432.0K0.02%––
Mackenzie Financial Corp9,783$440.0K0.00%––
Quantitative Investment Management, LLC9,931$446.0K0.04%––
Maryland State Retirement & Pension System9,956$448.0K0.02%––
Wrapmanager Inc10,512$473.0K0.13%––
Westpac Banking Corp10,594$476.3K0.01%––
Echo Street Capital Management LLC10,613$477.0K0.00%––
Nicollet Investment Management, Inc.10,811$486.0K0.21%––
Oppenheimer Asset Management Inc.10,936$491.0K0.01%––
Plancorp, LLC11,100$499.0K0.11%––
Blair William & Co11,164$502.0K0.00%––
KBC Group NV11,511$518.0K0.00%––
Bokf, NA11,710$526.0K0.01%––
Panagora Asset Management Inc12,145$546.0K0.00%––
Reynders McVeigh Capital Management, LLC12,174$547.0K0.04%––
Tower Research Capital LLC (TRC)12,323$554.0K0.01%––
Berkshire Asset Management LLC12,348$555.0K0.04%––
Voya Financial Advisors, Inc.12,433$556.0K0.02%––
Ritholtz Wealth Management12,501$562.0K0.05%––
Virtus ETF Advisers LLC13,084$588.0K0.25%––
Migdal Insurance & Financial Holdings Ltd.13,305$598.0K0.01%––
US Bancorp13,586$610.0K0.00%––
National Asset Management, Inc.12,998$616.0K0.02%––
North Star Asset Management Inc13,753$618.0K0.04%––
NN Investment Partners Holdings N.V.14,118$635.0K0.00%––
Nissay Asset Management Corp14,204$639.0K0.01%––
Virtu Financial LLC14,360$646.0K0.05%––
HSBC Holdings PLC14,415$648.0K0.00%––
Ameriprise Financial Inc14,478$652.0K0.00%––
Castle Rock Wealth Management, LLC15,593$662.0K0.27%––
Cambridge Investment Research Advisors, Inc.14,877$669.0K0.00%––
Comerica Bank15,696$670.0K0.00%––
Optimal Asset Management, Inc.15,118$680.0K0.09%––
Lincoln National Corp15,465$695.0K0.02%––
IFM Investors Pty Ltd15,830$712.0K0.02%––
Advisor Group Holdings, Inc.15,966$720.0K0.00%––
Arden Trust Co16,506$742.0K0.12%––
Emerald Advisers, LLC17,621$792.0K0.03%––
Alexandria Capital, LLC17,762$799.0K0.08%––
Toronto Dominion Bank17,977$808.0K0.00%––
Private Advisor Group, LLC18,042$811.0K0.01%––
Commonwealth Equity Services, LLC18,136$815.0K0.00%––
Public Employees Retirement Association of Colorado19,604$881.0K0.00%––
Squarepoint Ops LLC19,587$881.0K0.01%––
Amalgamated Bank19,666$884.0K0.03%––