Fulcrum Therapeutics, Inc.
FULC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001680581
In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Fulcrum Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 129
- +8 vs. Q2 2025
- Shares held
- 53.8M
- −604.5K (−1.1%) vs. Q2 2025
- Total value
- $494.9M
- +$120.4M (+32.2%) vs. Q2 2025
- New holders
- 26
- 40 more added
- Sold out
- 18
- 43 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 154 | $291.3M |
| Q1 2026 | 169 | $550.1M |
| Q4 2025 | 172 | $762.7M |
| Q3 2025 | 129 | $494.9M |
| Q2 2025 | 122 | $374.5M |
| Q1 2025 | 117 | $147.8M |
| Q4 2024 | 119 | $243.4M |
| Q3 2024 | 130 | $196.4M |
| Q2 2024 | 121 | $402.0M |
| Q1 2024 | 126 | $569.7M |
| Q4 2023 | 101 | $412.3M |
| Q3 2023 | 81 | $250.4M |
| Q2 2023 | 88 | $183.2M |
| Q1 2023 | 116 | $172.2M |
| Q4 2022 | 110 | $368.5M |
| Q3 2022 | 105 | $422.1M |
| Q2 2022 | 102 | $196.6M |
| Q1 2022 | 108 | $929.9M |
| Q4 2021 | 110 | $657.3M |
| Q3 2021 | 101 | $1.03B |
| Q2 2021 | 67 | $280.8M |
| Q1 2021 | 68 | $317.0M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Renaissance Technologies LLC | 248,200 | $2.28M | 0.00% | +169,700+216.2% | Added |
| Deutsche Bank AG | 285,329 | $2.63M | 0.00% | +6,078+2.2% | Added |
| Bessemer Group Inc | 286,988 | $2.64M | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 301,157 | $2.77M | 0.00% | +165,952+122.7% | Added |
| Jane Street Group, LLC | 321,520 | $2.96M | 0.00% | +304,093+1,745.0% | Added |
| Charles Schwab Investment Management Inc | 333,483 | $3.07M | 0.00% | −54,299−14.0% | Reduced |
| ADAR1 Capital Management, LLC | 341,612 | $3.14M | 0.31% | +288,263+540.3% | Added |
| Schonfeld Strategic Advisors LLC | 366,303 | $3.37M | 0.02% | +161,903+79.2% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 384,138 | $3.53M | 0.01% | +41,591+12.1% | Added |
| Acadian Asset Management LLC | 540,641 | $4.97M | 0.01% | −22,739−4.0% | Reduced |
| Northern Trust Corp | 568,322 | $5.23M | 0.00% | −43,214−7.1% | Reduced |
| Goldman Sachs Group Inc | 586,351 | $5.39M | 0.00% | −557,185−48.7% | Reduced |
| Boothbay Fund Management, LLC | 678,414 | $6.24M | 0.16% | +537,036+379.9% | Added |
| Citadel Advisors LLC | 854,556 | $7.86M | 0.01% | +688,322+414.1% | Added |
| Royal Bank of Canada | 1,000,849 | $9.21M | 0.00% | +996,632+23,633.7% | Added |
| Geode Capital Management, LLC | 1,004,051 | $9.24M | 0.00% | −189,087−15.8% | Reduced |
| State Street Corp | 1,063,207 | $9.78M | 0.00% | −155,159−12.7% | Reduced |
| Ikarian Capital, LLC | 1,289,225 | $11.9M | 2.69% | +860,704+200.9% | Added |
| Dimensional Fund Advisors LP | 1,299,308 | $12.0M | 0.00% | −73,329−5.3% | Reduced |
| D. E. Shaw & Co., Inc. | 1,449,423 | $13.3M | 0.01% | +272,712+23.2% | Added |
| Balyasny Asset Management LLC | 1,450,480 | $13.3M | 0.03% | +112,266+8.4% | Added |
| Adage Capital Partners GP, L.L.C. | 2,432,000 | $22.4M | 0.04% | −2,157,000−47.0% | Reduced |
| Vanguard Group Inc | 2,999,464 | $27.6M | 0.00% | −146,979−4.7% | Reduced |
| BlackRock, Inc. | 3,706,750 | $34.1M | 0.00% | −672,273−15.4% | Reduced |
| Nantahala Capital Management, LLC | 4,670,784 | $43.0M | 2.65% | +382,485+8.9% | Added |
| TCG Crossover Management, LLC | 5,250,000 | $48.3M | 2.38% | 00.0% | Unchanged |
| Suvretta Capital Management, LLC | 5,381,000 | $49.5M | 1.50% | +298,100+5.9% | Added |
| Ra Capital Management, L.P. | 10,229,099 | $94.1M | 1.16% | 00.0% | Unchanged |
| Summit Wealth Group LLC | 533 | – | – | +533 | New |
| Woodline Partners LP | 0 | $0 | 0.00% | −897,617−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −498,219−100.0% | Sold out |
| Catalio Capital Management, LP | 0 | $0 | 0.00% | −188,304−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −58,965−100.0% | Sold out |
| Integrated Quantitative Investments LLC | 0 | $0 | 0.00% | −41,106−100.0% | Sold out |
| Allostery Investments LP | 0 | $0 | 0.00% | −40,353−100.0% | Sold out |
| PDT Partners, LLC | 0 | $0 | 0.00% | −27,280−100.0% | Sold out |
| Sherbrooke Park Advisers LLC | 0 | $0 | 0.00% | −27,201−100.0% | Sold out |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −18,053−100.0% | Sold out |
| Evergreen Capital Management LLC | 0 | $0 | 0.00% | −16,502−100.0% | Sold out |
| Voya Investment Management LLC | 0 | $0 | 0.00% | −15,411−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −14,540−100.0% | Sold out |
| Los Angeles Capital Management LLC | 0 | $0 | 0.00% | −13,465−100.0% | Sold out |
| ProShare Advisors LLC | 0 | $0 | 0.00% | −10,951−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −6,281−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | $0 | 0.00% | −3,031−100.0% | Sold out |
| Point72 (DIFC) Ltd | 0 | $0 | 0.00% | −2,665−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −1,911−100.0% | Sold out |
| PrairieView Partners, LLC | – | – | – | – | Not filed |