Skip to main content

Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Fulcrum Therapeutics, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
110
+5 vs. Q3 2022
Shares held
50.6M
−1.55M (−3.0%) vs. Q3 2022
Total value
$368.5M
−$53.6M (−12.7%) vs. Q3 2022
New holders
22
47 more added
Sold out
17
25 more reduced

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 110 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ4 2022: $368.5M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q3 2022.

Institutions holding FULC in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.9,505,925$69.2M1.40%+2,505,925+35.8%Added
FMR LLC5,233,725$38.1M0.00%−2,571,917−32.9%Reduced
RTW Investments, LP4,993,279$36.4M0.74%+1,007,369+25.3%Added
Suvretta Capital Management, LLC4,274,803$31.1M1.31%+746,803+21.2%Added
BlackRock Inc.3,268,991$23.8M0.00%+496,647+17.9%Added
TRV GP IV, LLC2,343,154$17.1M7.25%00.0%Unchanged
Vanguard Group Inc2,120,623$15.4M0.00%+164,531+8.4%Added
Logos Global Management LP2,000,000$14.6M1.71%+50,000+2.6%Added
TRV GP III, LLC1,962,202$14.3M11.20%−2,000,000−50.5%Reduced
Cowen and Company, LLC1,361,169$9.91M1.05%−986,820−42.0%Reduced
Morgan Stanley1,173,611$8.54M0.00%−26,691−2.2%Reduced
Adage Capital Partners GP, L.L.C.1,120,000$8.15M0.02%−200,000−15.2%Reduced
Geode Capital Management, LLC855,832$6.23M0.00%+230,762+36.9%Added
Citadel Advisors LLC816,244$5.94M0.01%+174,112+27.1%Added
State Street Corp780,414$5.68M0.00%+54,897+7.6%Added
Deep Track Capital, LP768,607$5.60M0.24%−132,104−14.7%Reduced
Sofinnova Investments, Inc.631,411$4.60M0.28%−165,851−20.8%Reduced
Nantahala Capital Management, LLC500,000$3.64M0.33%+500,000New
VR Adviser, LLC447,326$3.26M0.55%−752,674−62.7%Reduced
Harvard Management Co Inc410,714$2.99M0.38%00.0%Unchanged
Northern Trust Corp390,476$2.84M0.00%+79,183+25.4%Added
Dimensional Fund Advisors LP386,832$2.82M0.00%+152,752+65.3%Added
Rock Springs Capital Management LP384,590$2.80M0.07%00.0%Unchanged
Norges Bank356,600$2.60M0.00%+356,600New
Goldman Sachs Group Inc315,428$2.30M0.00%−29,302−8.5%Reduced
Bessemer Group Inc286,988$2.09M0.01%+1,274+0.4%Added
Alphabet Inc.255,452$1.86M0.11%00.0%Unchanged
Nuveen Asset Management, LLC253,725$1.85M0.00%+95,519+60.4%Added
Parkman Healthcare Partners LLC206,866$1.51M0.40%−28,519−12.1%Reduced
Bank of New York Mellon Corp197,856$1.44M0.00%+65,383+49.4%Added
International Biotechnology Trust PLC193,741$1.41M0.44%00.0%Unchanged
Acuta Capital Partners, LLC185,000$1.35M0.83%−35,000−15.9%Reduced
JPMorgan Chase & Co184,686$1.34M0.00%−11,274−5.8%Reduced
D. E. Shaw & Co., Inc.176,146$1.28M0.00%+93,807+113.9%Added
Price T Rowe Associates Inc150,509$1.09M0.00%+105,904+237.4%Added
Fiduciary Trust Co136,555$994.1K0.02%+4,083+3.1%Added
Two Sigma Investments, LP133,019$968.4K0.00%+133,019New
State of Wisconsin Investment Board125,936$916.8K0.00%+62,249+97.7%Added
Charles Schwab Investment Management Inc114,887$836.4K0.00%+22,116+23.8%Added
Schonfeld Strategic Advisors LLC106,600$776.0K0.01%+40,000+60.1%Added
Man Group plc96,152$700.0K0.00%+10,394+12.1%Added
Swiss National Bank89,600$652.3K0.00%00.0%Unchanged
Susquehanna Fundamental Investments, LLC84,558$615.6K0.01%+26,758+46.3%Added
Two Sigma Advisers, LP64,000$465.9K0.00%+13,700+27.2%Added
Rhumbline Advisers59,730$435.0K0.00%+9,003+17.7%Added
J. Goldman & Co LP59,100$430.2K0.03%−89,400−60.2%Reduced
Tekla Capital Management LLC58,537$426.1K0.02%+58,537New
Bank of America Corp57,633$419.6K0.00%+27,815+93.3%Added
California State Teachers Retirement System50,324$366.4K0.00%+4,293+9.3%Added
Credit Suisse AG43,820$319.0K0.00%+21,230+94.0%Added
Alliancebernstein L.P.42,800$311.6K0.00%+5,200+13.8%Added
PDT Partners, LLC41,403$301.4K0.05%+41,403New
Bridgeway Capital Management, LLC40,000$291.2K0.01%−35,000−46.7%Reduced
Alps Advisors Inc35,358$257.4K0.00%+35,358New
Cornercap Investment Counsel Inc34,886$254.0K0.04%+34,886New
XTX Topco Ltd34,882$253.9K0.05%+34,882New
Voya Investment Management LLC34,871$253.9K0.00%+7,962+29.6%Added
Stifel Financial Corp34,300$249.7K0.00%+1,700+5.2%Added
Cubist Systematic Strategies, LLC30,702$223.5K0.00%−5,839−16.0%Reduced
Country Trust Bank30,186$219.8K0.01%00.0%Unchanged
Brandywine Managers, LLC26,127$190.2K0.66%00.0%Unchanged
Occudo Quantitative Strategies LP26,008$189.3K0.02%−6,636−20.3%Reduced
Panagora Asset Management Inc23,236$169.2K0.00%−5,825−20.0%Reduced
Graham Capital Management, L.P.21,353$155.4K0.01%+21,353New
Ameriprise Financial Inc20,994$153.0K0.00%+330+1.6%Added
American International Group, Inc.20,598$150.0K0.00%+4,386+27.1%Added
Blackstone Group Inc.19,216$139.9K0.00%+19,216New
MetLife Investment Management18,890$137.5K0.00%00.0%Unchanged
Deutsche Bank AG18,768$136.6K0.00%−4,962−20.9%Reduced
New York State Common Retirement Fund18,664$135.9K0.00%+40.0%Added
Old Well Partners, LLC17,300$125.9K0.11%+17,300New
Manufacturers Life Insurance Company, The17,020$123.9K0.00%+2,009+13.4%Added
SG Americas Securities, LLC16,033$117.0K0.00%+4,198+35.5%Added
Alpine Global Management, LLC16,073$117.0K0.04%+16,073New
Marshall Wace, LLP15,526$113.0K0.00%−4,589−22.8%Reduced
UBS Asset Management Americas Inc14,800$107.7K0.00%00.0%Unchanged
Legal & General Group Plc13,925$101.4K0.00%+1,066+8.3%Added
Mirae Asset Global Investments Co., Ltd.13,570$98.8K0.00%+18+0.1%Added
Invesco Ltd.12,978$94.5K0.00%+1,737+15.5%Added
Principal Financial Group Inc12,821$93.3K0.00%+12,821New
Barclays PLC11,692$85.1K0.00%+10,244+707.5%Added
Jane Street Group, LLC11,687$85.1K0.00%+11,687New
Corton Capital Inc.11,565$84.2K0.07%+11,565New
Landscape Capital Management, L.L.C.11,114$80.9K0.01%+11,114New
Arizona State Retirement System10,708$78.0K0.00%+428+4.2%Added
Delphia (USA) Inc.10,625$77.3K0.09%+10,625New
Bank Julius Baer & Co. Ltd, Zurich8,500$62.0K0.00%+134+1.6%Added
Royal Bank of Canada7,651$56.0K0.00%+7,216+1,658.9%Added
Ameritas Investment Partners, Inc.3,342$42.2K0.00%+1,300+63.7%Added
Amalgamated Bank5,724$42.0K0.00%+1,696+42.1%Added
UBS Group AG3,789$27.6K0.00%+3,789New
PrairieView Partners, LLC3,600$26.0K0.00%00.0%Unchanged
Wells Fargo & Company3,195$23.3K0.00%−2,358−42.5%Reduced
SVB Financial Group22,422$22.4K0.06%+22,422New
Zurcher Kantonalbank (Zurich Cantonalbank)2,655$19.3K0.00%00.0%Unchanged
Metropolitan Life Insurance Co2,078$15.1K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,824$13.0K0.00%−289−13.7%Reduced
Citigroup Inc1,753$12.8K0.00%−167−8.7%Reduced
Nisa Investment Advisors, LLC1,652$12.0K0.00%+509+44.5%Added
SOA Wealth Advisors, LLC.800$5.82K0.00%+800New