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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Fulcrum Therapeutics, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
116
+6 vs. Q4 2022
Shares held
60.4M
+9.78M (+19.3%) vs. Q4 2022
Total value
$172.2M
−$196.3M (−53.3%) vs. Q4 2022
New holders
27
51 more added
Sold out
21
22 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 116 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ1 2023: $172.2M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q4 2022.

Institutions holding FULC in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.11,609,704$33.1M0.75%+2,103,779+22.1%Added
FMR LLC6,156,328$17.5M0.00%+922,603+17.6%Added
RTW Investments, LP5,511,839$15.7M0.33%+518,560+10.4%Added
Suvretta Capital Management, LLC5,177,710$14.8M0.71%+902,907+21.1%Added
BlackRock Inc.4,183,738$11.9M0.00%+914,747+28.0%Added
Vanguard Group Inc2,878,491$8.20M0.00%+757,868+35.7%Added
Point72 Asset Management, L.P.2,643,672$7.53M0.03%+2,643,672New
TRV GP IV, LLC2,343,154$6.68M4.77%00.0%Unchanged
Cowen and Company, LLC2,176,045$6.20M0.73%+814,876+59.9%Added
Adage Capital Partners GP, L.L.C.1,806,422$5.15M0.01%+686,422+61.3%Added
VR Adviser, LLC1,307,094$3.73M0.73%+859,768+192.2%Added
Morgan Stanley1,162,368$3.31M0.00%−11,243−1.0%Reduced
Cormorant Asset Management, LP1,081,490$3.08M0.20%+1,081,490New
Geode Capital Management, LLC1,062,634$3.03M0.00%+206,802+24.2%Added
State Street Corp965,588$2.75M0.00%+185,174+23.7%Added
Dimensional Fund Advisors LP754,886$2.15M0.00%+368,054+95.1%Added
Rock Springs Capital Management LP727,673$2.07M0.05%+343,083+89.2%Added
Two Sigma Investments, LP649,810$1.85M0.01%+516,791+388.5%Added
Simplify Asset Management Inc.639,118$1.82M0.33%+639,118New
Millennium Management LLC620,559$1.77M0.00%+620,559New
Vivo Capital, LLC550,000$1.57M0.12%+550,000New
Northern Trust Corp451,952$1.29M0.00%+61,476+15.7%Added
Harvard Management Co Inc410,714$1.17M0.12%00.0%Unchanged
Norges Bank410,500$1.17M0.00%+53,900+15.1%Added
Renaissance Technologies LLC390,100$1.11M0.00%+390,100New
Squarepoint Ops LLC319,711$911.2K0.01%+319,711New
Goldman Sachs Group Inc297,811$848.8K0.00%−17,617−5.6%Reduced
Nuveen Asset Management, LLC288,737$823.0K0.00%+35,012+13.8%Added
Bessemer Group Inc286,988$818.0K0.00%00.0%Unchanged
Two Sigma Advisers, LP262,600$748.4K0.00%+198,600+310.3%Added
Bank of New York Mellon Corp212,201$604.8K0.00%+14,345+7.3%Added
Citadel Advisors LLC209,459$597.0K0.00%−606,785−74.3%Reduced
JPMorgan Chase & Co190,269$543.0K0.00%+5,583+3.0%Added
Alyeska Investment Group, L.P.152,148$433.6K0.00%+152,148New
Graham Capital Management, L.P.146,979$418.9K0.01%+125,626+588.3%Added
Charles Schwab Investment Management Inc141,311$402.7K0.00%+26,424+23.0%Added
Fiduciary Trust Co136,555$389.2K0.01%00.0%Unchanged
XTX Topco Ltd123,768$352.7K0.07%+88,886+254.8%Added
Marshall Wace, LLP121,000$344.9K0.00%+105,474+679.3%Added
State of Wisconsin Investment Board94,770$270.1K0.00%−31,166−24.7%Reduced
Candriam Luxembourg S.C.A.101,337$265.8K0.00%+101,337New
Swiss National Bank86,500$246.5K0.00%−3,100−3.5%Reduced
Rhumbline Advisers75,507$215.0K0.00%+15,777+26.4%Added
Cubist Systematic Strategies, LLC65,076$185.5K0.00%+34,374+112.0%Added
UBS Oconnor LLC62,274$177.5K0.00%+62,274New
Susquehanna International Group, LLP59,067$168.3K0.00%+59,067New
Tekla Capital Management LLC58,537$166.8K0.01%00.0%Unchanged
Alliancebernstein L.P.55,900$159.3K0.00%+13,100+30.6%Added
California State Teachers Retirement System54,299$154.8K0.00%+3,975+7.9%Added
Credit Suisse AG52,062$148.4K0.00%+8,242+18.8%Added
Cornercap Investment Counsel Inc44,078$125.6K0.02%+9,192+26.3%Added
Voya Investment Management LLC43,286$123.4K0.00%+8,415+24.1%Added
Bank of America Corp42,370$120.8K0.00%−15,263−26.5%Reduced
Susquehanna Fundamental Investments, LLC41,534$118.4K0.00%−43,024−50.9%Reduced
Alps Advisors Inc40,692$116.0K0.00%+5,334+15.1%Added
Occudo Quantitative Strategies LP39,239$111.8K0.01%+13,231+50.9%Added
Price T Rowe Associates Inc36,461$104.0K0.00%−114,048−75.8%Reduced
Stifel Financial Corp34,100$97.2K0.00%−200−0.6%Reduced
Mirae Asset Global Investments Co., Ltd.32,274$92.0K0.00%+18,704+137.8%Added
Deutsche Bank AG31,733$90.4K0.00%+12,965+69.1%Added
Virtu Financial LLC31,104$89.0K0.01%+31,104New
Country Trust Bank30,186$86.0K0.00%00.0%Unchanged
Engineers Gate Manager LP29,822$85.0K0.00%+29,822New
Y-Intercept (Hong Kong) Ltd29,663$84.5K0.01%+29,663New
PDT Partners, LLC28,603$81.5K0.01%−12,800−30.9%Reduced
MetLife Investment Management27,689$78.9K0.00%+8,799+46.6%Added
Barclays PLC27,253$77.7K0.00%+15,561+133.1%Added
Brandywine Managers, LLC26,127$74.5K0.05%00.0%Unchanged
UBS Asset Management Americas Inc25,699$73.2K0.00%+10,899+73.6%Added
SG Americas Securities, LLC24,951$71.0K0.00%+8,918+55.6%Added
American International Group, Inc.24,899$71.0K0.00%+4,301+20.9%Added
Panagora Asset Management Inc22,299$63.6K0.00%−937−4.0%Reduced
Nantahala Capital Management, LLC21,370$60.9K0.01%−478,630−95.7%Reduced
American Century Companies Inc20,203$57.2K0.00%+20,203New
Blackstone Group Inc.19,216$54.8K0.00%00.0%Unchanged
Janus Henderson Group PLC18,972$54.0K0.00%+18,972New
Old Well Partners, LLC17,300$49.3K0.04%00.0%Unchanged
Manufacturers Life Insurance Company, The17,020$48.5K0.00%00.0%Unchanged
New York State Common Retirement Fund15,843$45.2K0.00%−2,821−15.1%Reduced
D. E. Shaw & Co., Inc.15,323$43.7K0.00%−160,823−91.3%Reduced
Principal Financial Group Inc15,292$43.6K0.00%+2,471+19.3%Added
Alphabet Inc.14,262$40.6K0.00%−241,190−94.4%Reduced
Jane Street Group, LLC14,254$40.6K0.00%+2,567+22.0%Added
Landscape Capital Management, L.L.C.13,740$39.2K0.01%+2,626+23.6%Added
Corton Capital Inc.13,441$38.3K0.03%+1,876+16.2%Added
Invesco Ltd.12,469$35.5K0.00%−509−3.9%Reduced
Teacher Retirement System of Texas12,349$35.0K0.00%+12,349New
Quantamental Technologies LLC12,155$34.6K0.02%+12,155New
Verition Fund Management LLC11,772$33.5K0.00%+11,772New
Arizona State Retirement System11,614$33.1K0.00%+906+8.5%Added
Delphia (USA) Inc.10,895$31.1K0.04%+270+2.5%Added
Zurcher Kantonalbank (Zurich Cantonalbank)10,449$29.8K0.00%+7,794+293.6%Added
ProShare Advisors LLC10,347$29.5K0.00%+10,347New
Wells Fargo & Company9,766$27.8K0.00%+6,571+205.7%Added
Legal & General Group Plc9,496$27.1K0.00%−4,429−31.8%Reduced
Bank Julius Baer & Co. Ltd, Zurich8,500$24.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)5,920$17.0K0.00%+4,096+224.6%Added
Amalgamated Bank5,054$14.0K0.00%−670−11.7%Reduced
Point72 Middle East FZE4,311$12.3K0.00%+4,311New
PrairieView Partners, LLC3,600$10.0K0.00%00.0%Unchanged