Fulcrum Therapeutics, Inc.
FULC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001680581
In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Fulcrum Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 117
- −1 vs. Q4 2024
- Shares held
- 51.4M
- −189.6K (−0.4%) vs. Q4 2024
- Total value
- $147.8M
- −$94.8M (−39.1%) vs. Q4 2024
- New holders
- 18
- 31 more added
- Sold out
- 19
- 43 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 154 | $291.3M |
| Q1 2026 | 169 | $550.1M |
| Q4 2025 | 172 | $762.7M |
| Q3 2025 | 129 | $494.9M |
| Q2 2025 | 122 | $374.5M |
| Q1 2025 | 117 | $147.8M |
| Q4 2024 | 119 | $243.4M |
| Q3 2024 | 130 | $196.4M |
| Q2 2024 | 121 | $402.0M |
| Q1 2024 | 126 | $569.7M |
| Q4 2023 | 101 | $412.3M |
| Q3 2023 | 81 | $250.4M |
| Q2 2023 | 88 | $183.2M |
| Q1 2023 | 116 | $172.2M |
| Q4 2022 | 110 | $368.5M |
| Q3 2022 | 105 | $422.1M |
| Q2 2022 | 102 | $196.6M |
| Q1 2022 | 108 | $929.9M |
| Q4 2021 | 110 | $657.3M |
| Q3 2021 | 101 | $1.03B |
| Q2 2021 | 67 | $280.8M |
| Q1 2021 | 68 | $317.0M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 10,229,099 | $29.5M | 0.49% | 00.0% | Unchanged |
| TCG Crossover Management, LLC | 5,250,000 | $15.1M | 2.06% | 00.0% | Unchanged |
| Suvretta Capital Management, LLC | 5,067,394 | $14.6M | 0.59% | +1,728,928+51.8% | Added |
| Nantahala Capital Management, LLC | 4,822,693 | $13.9M | 1.15% | +42,985+0.9% | Added |
| BlackRock, Inc. | 4,710,697 | $13.6M | 0.00% | −458,732−8.9% | Reduced |
| Vanguard Group Inc | 3,220,378 | $9.27M | 0.00% | −29,229−0.9% | Reduced |
| Adage Capital Partners GP, L.L.C. | 3,000,000 | $8.64M | 0.02% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 1,407,049 | $4.05M | 0.00% | −11,641−0.8% | Reduced |
| State Street Corp | 1,252,440 | $3.61M | 0.00% | +7,121+0.6% | Added |
| Geode Capital Management, LLC | 1,231,375 | $3.55M | 0.00% | −63,140−4.9% | Reduced |
| Woodline Partners LP | 897,617 | $2.59M | 0.02% | −512,903−36.4% | Reduced |
| Exome Asset Management LLC | 689,137 | $1.98M | 1.78% | +405,538+143.0% | Added |
| Northern Trust Corp | 640,947 | $1.85M | 0.00% | −69,374−9.8% | Reduced |
| D. E. Shaw & Co., Inc. | 580,661 | $1.67M | 0.00% | −2,542−0.4% | Reduced |
| ADAR1 Capital Management, LLC | 490,532 | $1.41M | 0.27% | +294,284+150.0% | Added |
| Goldman Sachs Group Inc | 402,600 | $1.16M | 0.00% | −139,658−25.8% | Reduced |
| Renaissance Technologies LLC | 401,100 | $1.16M | 0.00% | +401,100 | New |
| Charles Schwab Investment Management Inc | 381,359 | $1.10M | 0.00% | −144,686−27.5% | Reduced |
| Citadel Advisors LLC | 374,256 | $1.08M | 0.00% | +40,933+12.3% | Added |
| Acadian Asset Management LLC | 344,561 | $989.0K | 0.00% | +308,854+865.0% | Added |
| Bessemer Group Inc | 286,988 | $827.0K | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 285,599 | $822.5K | 0.00% | −1,246,133−81.4% | Reduced |
| Deutsche Bank AG | 279,812 | $805.9K | 0.00% | −5,679−2.0% | Reduced |
| Two Sigma Advisers, LP | 277,800 | $800.1K | 0.00% | −65,800−19.2% | Reduced |
| Shay Capital LLC | 224,305 | $646.0K | 0.19% | −77,159−25.6% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 217,749 | $627.1K | 0.00% | −149,845−40.8% | Reduced |
| JPMorgan Chase & Co | 209,893 | $604.5K | 0.00% | +130,773+165.3% | Added |
| Catalio Capital Management, LP | 202,139 | $582.2K | 0.14% | +202,139 | New |
| Ikarian Capital, LLC | 200,096 | $576.3K | 0.19% | 00.0% | Unchanged |
| Prelude Capital Management, LLC | 192,207 | $553.6K | 0.06% | +106,122+123.3% | Added |
| Graham Capital Management, L.P. | 166,243 | $478.8K | 0.02% | +21,301+14.7% | Added |
| Nuveen, LLC | 152,992 | $440.6K | 0.00% | +152,992 | New |
| Susquehanna Fundamental Investments, LLC | 150,643 | $433.9K | 0.01% | −62,570−29.3% | Reduced |
| Two Sigma Investments, LP | 150,274 | $432.8K | 0.00% | −19,268−11.4% | Reduced |
| Jacobs Levy Equity Management, Inc | 147,654 | $425.2K | 0.00% | +147,654 | New |
| Bank of New York Mellon Corp | 143,588 | $413.5K | 0.00% | +1,715+1.2% | Added |
| Fiduciary Trust Co | 136,555 | $393.3K | 0.01% | 00.0% | Unchanged |
| American Century Companies Inc | 123,711 | $356.3K | 0.00% | +3,100+2.6% | Added |
| Jane Street Group, LLC | 117,816 | $339.3K | 0.00% | +72,657+160.9% | Added |
| Bridgeway Capital Management, LLC | 97,600 | $281.1K | 0.01% | −42,400−30.3% | Reduced |
| Matisse Capital | 96,717 | $278.5K | 0.15% | −31,728−24.7% | Reduced |
| STRS Ohio | 91,200 | $262.7K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 88,993 | $256.3K | 0.00% | +386+0.4% | Added |
| Invesco Ltd. | 85,767 | $247.0K | 0.00% | +55,791+186.1% | Added |
| Commonwealth Equity Services, LLC | 83,428 | $240.0K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 82,457 | $237.5K | 0.00% | −39,613−32.5% | Reduced |
| Simplify Asset Management Inc. | 81,134 | $233.7K | 0.01% | +420+0.5% | Added |
| RBF Capital, LLC | 80,506 | $231.9K | 0.01% | 00.0% | Unchanged |
| HSBC Holdings PLC | 74,961 | $218.5K | 0.00% | −998−1.3% | Reduced |
| UBS Group AG | 71,920 | $207.1K | 0.00% | −5,472−7.1% | Reduced |
| Price T Rowe Associates Inc | 70,168 | $203.0K | 0.00% | +17,800+34.0% | Added |
| Alliancebernstein L.P. | 65,590 | $188.9K | 0.00% | 00.0% | Unchanged |
| Verition Fund Management LLC | 65,388 | $188.3K | 0.00% | −1,655−2.5% | Reduced |
| Susquehanna International Group, LLP | 64,840 | $186.7K | 0.00% | +24,063+59.0% | Added |
| Boothbay Fund Management, LLC | 59,533 | $171.5K | 0.01% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 57,070 | $164.4K | 0.00% | +57,070 | New |
| Bank of America Corp | 56,135 | $161.7K | 0.00% | −35,731−38.9% | Reduced |
| Sherbrooke Park Advisers LLC | 55,342 | $159.4K | 0.07% | +10,185+22.6% | Added |
| HRT Financial LP | 50,490 | $145.0K | 0.00% | −17,579−25.8% | Reduced |
| XTX Topco Ltd | 49,878 | $143.6K | 0.01% | +49,878 | New |
| Intech Investment Management LLC | 45,689 | $131.6K | 0.00% | +15,190+49.8% | Added |
| Millennium Management LLC | 40,692 | $117.2K | 0.00% | −35,431−46.5% | Reduced |
| Citigroup Inc | 37,829 | $108.9K | 0.00% | −11,893−23.9% | Reduced |
| Algert Global LLC | 36,147 | $104.1K | 0.00% | +2,030+6.0% | Added |
| Y-Intercept (Hong Kong) Ltd | 32,086 | $92.4K | 0.01% | +32,086 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 31,592 | $91.0K | 0.00% | −4,009−11.3% | Reduced |
| Wells Fargo & Company | 30,520 | $87.9K | 0.00% | −3,744−10.9% | Reduced |
| Country Trust Bank | 30,186 | $86.9K | 0.00% | 00.0% | Unchanged |
| Corebridge Financial, Inc. | 26,381 | $76.0K | 0.00% | −4,469−14.5% | Reduced |
| SG Americas Securities, LLC | 25,375 | $73.0K | 0.00% | −5,067−16.6% | Reduced |
| Franklin Resources Inc | 24,821 | $71.5K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 22,725 | $65.4K | 0.00% | +50+0.2% | Added |
| Manufacturers Life Insurance Company, The | 22,411 | $64.5K | 0.00% | −1,059−4.5% | Reduced |
| Zacks Investment Management | 20,999 | $60.5K | 0.00% | 00.0% | Unchanged |
| J. Goldman & Co LP | 20,250 | $58.3K | 0.00% | 00.0% | Unchanged |
| Voya Investment Management LLC | 18,548 | $53.4K | 0.00% | −1,340−6.7% | Reduced |
| AQR Capital Management LLC | 17,608 | $50.7K | 0.00% | −28,033−61.4% | Reduced |
| MetLife Investment Management | 17,535 | $50.5K | 0.00% | −22,572−56.3% | Reduced |
| BNP Paribas Arbitrage, SA | 15,586 | $44.9K | 0.00% | +7,572+94.5% | Added |
| Alphabet Inc. | 14,262 | $41.1K | 0.00% | 00.0% | Unchanged |
| Virtu Financial LLC | 13,564 | $39.0K | 0.00% | +13,564 | New |
| New York State Common Retirement Fund | 13,100 | $37.7K | 0.00% | 00.0% | Unchanged |
| Jain Global LLC | 13,051 | $37.6K | 0.00% | −2,358−15.3% | Reduced |
| Engineers Gate Manager LP | 12,519 | $36.1K | 0.00% | +12,519 | New |
| Police & Firemen's Retirement System of New Jersey | 12,475 | $35.9K | 0.00% | 00.0% | Unchanged |
| Skopos Labs, Inc. | 12,190 | $35.1K | 0.01% | +8,254+209.7% | Added |
| CIBC World Markets Corp | 11,949 | $34.4K | 0.00% | +11,949 | New |
| ProShare Advisors LLC | 11,657 | $33.6K | 0.00% | −5,818−33.3% | Reduced |
| Jump Financial, LLC | 10,550 | $30.4K | 0.00% | +10,550 | New |
| JustInvest LLC | 10,266 | $29.6K | 0.00% | +10,266 | New |
| Tower Research Capital LLC (TRC) | 8,332 | $24.0K | 0.00% | +4,357+109.6% | Added |
| Group One Trading, L.P. | 6,792 | $19.6K | 0.00% | −22,697−77.0% | Reduced |
| Ameritas Investment Partners, Inc. | 6,079 | $17.5K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 5,288 | $15.2K | 0.00% | −1,232−18.9% | Reduced |
| PrairieView Partners, LLC | 5,000 | $14.0K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 4,496 | $12.9K | 0.00% | 00.0% | Unchanged |
| FMR LLC | 4,318 | $12.4K | 0.00% | −86,147−95.2% | Reduced |
| Nisa Investment Advisors, LLC | 4,015 | $11.6K | 0.00% | +2,348+140.9% | Added |
| IFP Advisors, Inc | 2,812 | $8.10K | 0.00% | +518+22.6% | Added |
| Simplex Trading, LLC | 3,026 | $8.00K | 0.00% | −7,429−71.1% | Reduced |