Fulcrum Therapeutics, Inc.
FULC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001680581
In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.
13F holders, Q1 2022
Institutional positions in Fulcrum Therapeutics, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 108
- −1 vs. Q4 2021
- Shares held
- 39.5M
- +2.30M (+6.2%) vs. Q4 2021
- Total value
- $929.9M
- +$273.2M (+41.6%) vs. Q4 2021
- New holders
- 21
- 29 more added
- Sold out
- 22
- 38 more reduced
1 institution that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 154 | $291.3M |
| Q1 2026 | 169 | $550.1M |
| Q4 2025 | 172 | $762.7M |
| Q3 2025 | 129 | $494.9M |
| Q2 2025 | 122 | $374.5M |
| Q1 2025 | 117 | $147.8M |
| Q4 2024 | 119 | $243.4M |
| Q3 2024 | 130 | $196.4M |
| Q2 2024 | 121 | $402.0M |
| Q1 2024 | 126 | $569.7M |
| Q4 2023 | 101 | $412.3M |
| Q3 2023 | 81 | $250.4M |
| Q2 2023 | 88 | $183.2M |
| Q1 2023 | 116 | $172.2M |
| Q4 2022 | 110 | $368.5M |
| Q3 2022 | 105 | $422.1M |
| Q2 2022 | 102 | $196.6M |
| Q1 2022 | 108 | $929.9M |
| Q4 2021 | 110 | $657.3M |
| Q3 2021 | 101 | $1.03B |
| Q2 2021 | 67 | $280.8M |
| Q1 2021 | 68 | $317.0M |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 6,096,478 | $144.2M | 0.01% | +14,161+0.2% | Added |
| TRV GP III, LLC | 3,962,202 | $93.7M | 25.43% | 00.0% | Unchanged |
| RTW Investments, LP | 3,611,194 | $85.4M | 1.77% | −255,678−6.6% | Reduced |
| Cowen and Company, LLC | 3,453,371 | $81.7M | 8.23% | +3,453,371 | New |
| Suvretta Capital Management, LLC | 2,613,412 | $61.8M | 1.89% | +237,841+10.0% | Added |
| TRV GP IV, LLC | 2,343,154 | $55.4M | 20.30% | 00.0% | Unchanged |
| BlackRock Inc. | 2,228,610 | $52.7M | 0.00% | +20,532+0.9% | Added |
| Adage Capital Partners GP, L.L.C. | 1,950,000 | $46.1M | 0.09% | +230,000+13.4% | Added |
| Vanguard Group Inc | 1,503,821 | $35.6M | 0.00% | +35,162+2.4% | Added |
| Morgan Stanley | 1,108,424 | $26.2M | 0.00% | +1,018,874+1,137.8% | Added |
| Logos Global Management LP | 1,000,000 | $23.6M | 3.07% | +315,000+46.0% | Added |
| State Street Corp | 675,954 | $16.0M | 0.00% | −21,957−3.1% | Reduced |
| Deep Track Capital, LP | 650,000 | $15.4M | 0.99% | −100,000−13.3% | Reduced |
| D. E. Shaw & Co., Inc. | 547,404 | $12.9M | 0.02% | −304,744−35.8% | Reduced |
| Geode Capital Management, LLC | 530,137 | $12.5M | 0.00% | +32,132+6.5% | Added |
| Polar Capital Holdings Plc | 500,000 | $11.8M | 0.07% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 434,590 | $10.3M | 0.26% | −22,400−4.9% | Reduced |
| Harvard Management Co Inc | 410,714 | $9.71M | 0.98% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 325,000 | $7.69M | 0.03% | −180,655−35.7% | Reduced |
| Perceptive Advisors LLC | 294,118 | $6.96M | 0.14% | 00.0% | Unchanged |
| Bessemer Group Inc | 285,714 | $6.76M | 0.01% | −23,707−7.7% | Reduced |
| Dimensional Fund Advisors LP | 282,793 | $6.69M | 0.00% | +95,272+50.8% | Added |
| Northern Trust Corp | 256,926 | $6.08M | 0.00% | −6,147−2.3% | Reduced |
| Alphabet Inc. | 255,452 | $6.04M | 0.20% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 237,642 | $5.62M | 0.00% | +152,759+180.0% | Added |
| Monashee Investment Management LLC | 236,991 | $5.60M | 1.62% | −36,054−13.2% | Reduced |
| Sofinnova Investments, Inc. | 229,509 | $5.43M | 0.46% | −388,161−62.8% | Reduced |
| Invesco Ltd. | 223,460 | $5.28M | 0.00% | +115,993+107.9% | Added |
| Paradigm Biocapital Advisors LP | 212,961 | $5.04M | 1.33% | +212,961 | New |
| Nuveen Asset Management, LLC | 291,332 | $4.97M | 0.00% | −88,314−23.3% | Reduced |
| JPMorgan Chase & Co | 200,386 | $4.74M | 0.00% | −2,487−1.2% | Reduced |
| Acuta Capital Partners, LLC | 200,000 | $4.73M | 2.25% | 00.0% | Unchanged |
| Lord, Abbett & Co. LLC | 188,651 | $4.46M | 0.01% | +3,417+1.8% | Added |
| Parkman Healthcare Partners LLC | 164,453 | $3.89M | 1.14% | −85,653−34.2% | Reduced |
| Opaleye Management Inc. | 136,000 | $3.22M | 1.00% | +136,000 | New |
| Fiduciary Trust Co | 132,472 | $3.13M | 0.06% | 00.0% | Unchanged |
| First Manhattan Co | 116,622 | $2.76M | 0.01% | +116,622 | New |
| Citadel Advisors LLC | 112,203 | $2.65M | 0.00% | −58,758−34.4% | Reduced |
| Bank of New York Mellon Corp | 100,639 | $2.38M | 0.00% | −310.0% | Reduced |
| Norges Bank | 87,100 | $2.06M | 0.00% | +87,100 | New |
| Two Sigma Advisers, LP | 85,500 | $2.02M | 0.01% | −293,600−77.4% | Reduced |
| Tekla Capital Management LLC | 77,293 | $1.83M | 0.06% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 72,209 | $1.71M | 0.00% | +1,724+2.4% | Added |
| Cinctive Capital Management LP | 66,120 | $1.56M | 0.07% | +30,000+83.1% | Added |
| Swiss National Bank | 62,400 | $1.48M | 0.00% | +6,200+11.0% | Added |
| Fred Alger Management, LLC | 48,921 | $1.16M | 0.00% | +48,921 | New |
| Schonfeld Strategic Advisors LLC | 39,600 | $936.0K | 0.01% | +4,100+11.5% | Added |
| International Biotechnology Trust PLC | 82,741 | $833.0K | 0.37% | +21,741+35.6% | Added |
| Country Trust Bank | 35,186 | $832.0K | 0.02% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 34,900 | $825.0K | 0.00% | −22,400−39.1% | Reduced |
| California State Teachers Retirement System | 34,642 | $819.0K | 0.00% | −2,062−5.6% | Reduced |
| Rhumbline Advisers | 34,115 | $807.0K | 0.00% | +2,408+7.6% | Added |
| Squarepoint Ops LLC | 30,369 | $718.0K | 0.01% | +11,140+57.9% | Added |
| Citigroup Inc | 29,228 | $691.0K | 0.00% | −11,205−27.7% | Reduced |
| Panagora Asset Management Inc | 28,646 | $677.0K | 0.00% | +106+0.4% | Added |
| Brandywine Managers, LLC | 26,127 | $618.0K | 1.07% | +847+3.4% | Added |
| Deutsche Bank AG | 25,299 | $598.0K | 0.00% | −2,088−7.6% | Reduced |
| Price T Rowe Associates Inc | 25,205 | $596.0K | 0.00% | −109,550−81.3% | Reduced |
| Barclays PLC | 23,380 | $553.0K | 0.00% | +23,380 | New |
| Alliancebernstein L.P. | 21,600 | $511.0K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 18,601 | $440.0K | 0.00% | +16+0.1% | Added |
| Credit Suisse AG | 18,156 | $429.0K | 0.00% | −596−3.2% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 17,797 | $421.0K | 0.00% | +1,055+6.3% | Added |
| Ensign Peak Advisors, Inc | 17,200 | $407.0K | 0.00% | +2,230+14.9% | Added |
| Nisa Investment Advisors, LLC | 17,200 | $407.0K | 0.00% | +14,840+628.8% | Added |
| Two Sigma Investments, LP | 16,900 | $400.0K | 0.00% | −504,090−96.8% | Reduced |
| Simplex Trading, LLC | 16,627 | $393.0K | 0.01% | +16,627 | New |
| Legal & General Group Plc | 16,328 | $385.0K | 0.00% | −1,930−10.6% | Reduced |
| MetLife Investment Management | 15,001 | $354.8K | 0.00% | +5,446+57.0% | Added |
| Jane Street Group, LLC | 14,958 | $354.0K | 0.00% | −16,281−52.1% | Reduced |
| Bank of America Corp | 14,831 | $351.0K | 0.00% | −13,133−47.0% | Reduced |
| UBS Asset Management Americas Inc | 14,800 | $350.0K | 0.00% | +14,800 | New |
| Wells Fargo & Company | 14,053 | $332.0K | 0.00% | −8,765−38.4% | Reduced |
| American International Group, Inc. | 13,645 | $323.0K | 0.00% | −961−6.6% | Reduced |
| Victory Capital Management Inc | 28,907 | $278.0K | 0.00% | +28,907 | New |
| Manufacturers Life Insurance Company, The | 11,572 | $273.7K | 0.00% | −2,769−19.3% | Reduced |
| Voya Investment Management LLC | 11,378 | $269.0K | 0.00% | +1,297+12.9% | Added |
| Cubist Systematic Strategies, LLC | 10,887 | $257.0K | 0.00% | −14,037−56.3% | Reduced |
| Corton Capital Inc. | 9,912 | $234.0K | 0.10% | +9,912 | New |
| Virtus ETF Advisers LLC | 9,496 | $225.0K | 0.10% | −563−5.6% | Reduced |
| Blackstone Group Inc. | 9,500 | $225.0K | 0.00% | +9,500 | New |
| ProShare Advisors LLC | 9,351 | $221.0K | 0.00% | −2,361−20.2% | Reduced |
| Bank Julius Baer & Co. Ltd, Zurich | 8,500 | $201.0K | 0.00% | 00.0% | Unchanged |
| Belvedere Trading LLC | 15,785 | $201.0K | 0.14% | +15,785 | New |
| STRS Ohio | 6,800 | $160.0K | 0.00% | −1,000−12.8% | Reduced |
| Allspring Global Investments Holdings, LLC | 5,277 | $124.0K | 0.00% | −595−10.1% | Reduced |
| Quantbot Technologies LP | 4,600 | $108.0K | 0.01% | +4,600 | New |
| SG Americas Securities, LLC | 4,289 | $101.0K | 0.00% | −7,563−63.8% | Reduced |
| Caption Management, LLC | 4,187 | $99.0K | 0.01% | +4,187 | New |
| Denali Advisors LLC | 3,900 | $92.0K | 0.04% | 00.0% | Unchanged |
| Amalgamated Bank | 3,324 | $79.0K | 0.00% | +3,324 | New |
| Amalgamated Financial Corp. | 3,324 | $79.0K | 0.00% | +3,324 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 2,655 | $63.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 2,042 | $48.0K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 1,783 | $42.2K | 0.00% | −5,446−75.3% | Reduced |
| Royal Bank of Canada | 1,696 | $40.0K | 0.00% | −2,887−63.0% | Reduced |
| UBS Group AG | 1,469 | $35.0K | 0.00% | +644+78.1% | Added |
| Cutler Group LP | 900 | $21.0K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 790 | $19.0K | 0.00% | +790 | New |
| Lindbrook Capital, LLC | 799 | $19.0K | 0.00% | +799 | New |