Fulcrum Therapeutics, Inc.
FULC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001680581
In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Fulcrum Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 129
- +8 vs. Q2 2025
- Shares held
- 53.8M
- −604.5K (−1.1%) vs. Q2 2025
- Total value
- $494.9M
- +$120.4M (+32.2%) vs. Q2 2025
- New holders
- 26
- 40 more added
- Sold out
- 18
- 43 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 154 | $291.3M |
| Q1 2026 | 169 | $550.1M |
| Q4 2025 | 172 | $762.7M |
| Q3 2025 | 129 | $494.9M |
| Q2 2025 | 122 | $374.5M |
| Q1 2025 | 117 | $147.8M |
| Q4 2024 | 119 | $243.4M |
| Q3 2024 | 130 | $196.4M |
| Q2 2024 | 121 | $402.0M |
| Q1 2024 | 126 | $569.7M |
| Q4 2023 | 101 | $412.3M |
| Q3 2023 | 81 | $250.4M |
| Q2 2023 | 88 | $183.2M |
| Q1 2023 | 116 | $172.2M |
| Q4 2022 | 110 | $368.5M |
| Q3 2022 | 105 | $422.1M |
| Q2 2022 | 102 | $196.6M |
| Q1 2022 | 108 | $929.9M |
| Q4 2021 | 110 | $657.3M |
| Q3 2021 | 101 | $1.03B |
| Q2 2021 | 67 | $280.8M |
| Q1 2021 | 68 | $317.0M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 10,229,099 | $94.1M | 1.16% | 00.0% | Unchanged |
| Suvretta Capital Management, LLC | 5,381,000 | $49.5M | 1.50% | +298,100+5.9% | Added |
| TCG Crossover Management, LLC | 5,250,000 | $48.3M | 2.38% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 4,670,784 | $43.0M | 2.65% | +382,485+8.9% | Added |
| BlackRock, Inc. | 3,706,750 | $34.1M | 0.00% | −672,273−15.4% | Reduced |
| Vanguard Group Inc | 2,999,464 | $27.6M | 0.00% | −146,979−4.7% | Reduced |
| Adage Capital Partners GP, L.L.C. | 2,432,000 | $22.4M | 0.04% | −2,157,000−47.0% | Reduced |
| Balyasny Asset Management LLC | 1,450,480 | $13.3M | 0.03% | +112,266+8.4% | Added |
| D. E. Shaw & Co., Inc. | 1,449,423 | $13.3M | 0.01% | +272,712+23.2% | Added |
| Dimensional Fund Advisors LP | 1,299,308 | $12.0M | 0.00% | −73,329−5.3% | Reduced |
| Ikarian Capital, LLC | 1,289,225 | $11.9M | 2.69% | +860,704+200.9% | Added |
| State Street Corp | 1,063,207 | $9.78M | 0.00% | −155,159−12.7% | Reduced |
| Geode Capital Management, LLC | 1,004,051 | $9.24M | 0.00% | −189,087−15.8% | Reduced |
| Royal Bank of Canada | 1,000,849 | $9.21M | 0.00% | +996,632+23,633.7% | Added |
| Citadel Advisors LLC | 854,556 | $7.86M | 0.01% | +688,322+414.1% | Added |
| Boothbay Fund Management, LLC | 678,414 | $6.24M | 0.16% | +537,036+379.9% | Added |
| Goldman Sachs Group Inc | 586,351 | $5.39M | 0.00% | −557,185−48.7% | Reduced |
| Northern Trust Corp | 568,322 | $5.23M | 0.00% | −43,214−7.1% | Reduced |
| Acadian Asset Management LLC | 540,641 | $4.97M | 0.01% | −22,739−4.0% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 384,138 | $3.53M | 0.01% | +41,591+12.1% | Added |
| Schonfeld Strategic Advisors LLC | 366,303 | $3.37M | 0.02% | +161,903+79.2% | Added |
| ADAR1 Capital Management, LLC | 341,612 | $3.14M | 0.31% | +288,263+540.3% | Added |
| Charles Schwab Investment Management Inc | 333,483 | $3.07M | 0.00% | −54,299−14.0% | Reduced |
| Jane Street Group, LLC | 321,520 | $2.96M | 0.00% | +304,093+1,745.0% | Added |
| UBS Group AG | 301,157 | $2.77M | 0.00% | +165,952+122.7% | Added |
| Bessemer Group Inc | 286,988 | $2.64M | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 285,329 | $2.63M | 0.00% | +6,078+2.2% | Added |
| Renaissance Technologies LLC | 248,200 | $2.28M | 0.00% | +169,700+216.2% | Added |
| Morgan Stanley | 243,835 | $2.24M | 0.00% | −70,575−22.4% | Reduced |
| Braidwell LP | 219,488 | $2.02M | 0.06% | +219,488 | New |
| Wellington Management Group LLP | 179,358 | $1.65M | 0.00% | +52,956+41.9% | Added |
| American Century Companies Inc | 152,244 | $1.40M | 0.00% | +19,895+15.0% | Added |
| Millennium Management LLC | 150,867 | $1.39M | 0.00% | +45,174+42.7% | Added |
| Bank of America Corp | 147,211 | $1.35M | 0.00% | +101,222+220.1% | Added |
| Standard Life Aberdeen plc | 137,961 | $1.27M | 0.00% | +79,265+135.0% | Added |
| Fiduciary Trust Co | 136,555 | $1.26M | 0.01% | 00.0% | Unchanged |
| J. Goldman & Co LP | 135,000 | $1.24M | 0.05% | +67,500+100.0% | Added |
| HRT Financial LP | 124,924 | $1.15M | 0.00% | +124,924 | New |
| Ameriprise Financial Inc | 124,666 | $1.15M | 0.00% | +124,666 | New |
| Invesco Ltd. | 123,872 | $1.14M | 0.00% | −346,461−73.7% | Reduced |
| Bank of New York Mellon Corp | 119,158 | $1.10M | 0.00% | −17,842−13.0% | Reduced |
| Gsa Capital Partners LLP | 116,068 | $1.07M | 0.09% | +83,505+256.4% | Added |
| Nuveen, LLC | 112,203 | $1.03M | 0.00% | −12,520−10.0% | Reduced |
| Susquehanna Fundamental Investments, LLC | 111,582 | $1.03M | 0.04% | 00.0% | Unchanged |
| Campbell & CO Investment Adviser LLC | 102,470 | $942.7K | 0.07% | +102,470 | New |
| Exome Asset Management LLC | 98,799 | $909.0K | 0.60% | −346,150−77.8% | Reduced |
| Bridgeway Capital Management, LLC | 95,400 | $877.7K | 0.02% | −2,200−2.3% | Reduced |
| Barclays PLC | 89,616 | $824.5K | 0.00% | −22,447−20.0% | Reduced |
| Commonwealth Equity Services, LLC | 83,428 | $768.0K | 0.00% | 00.0% | Unchanged |
| Simplify Asset Management Inc. | 83,234 | $765.8K | 0.02% | +10,080+13.8% | Added |
| RBF Capital, LLC | 80,506 | $740.7K | 0.03% | 00.0% | Unchanged |
| STRS Ohio | 77,900 | $716.7K | 0.00% | +2,800+3.7% | Added |
| Alliancebernstein L.P. | 74,590 | $686.2K | 0.00% | 00.0% | Unchanged |
| Jacobs Levy Equity Management, Inc | 70,015 | $644.1K | 0.00% | −22,455−24.3% | Reduced |
| Rhumbline Advisers | 69,372 | $638.2K | 0.00% | −13,878−16.7% | Reduced |
| Principal Financial Group Inc | 66,550 | $612.3K | 0.00% | +66,550 | New |
| DekaBank Deutsche Girozentrale | 60,000 | $611.0K | 0.00% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 65,892 | $607.0K | 0.00% | −3,136−4.5% | Reduced |
| Franklin Resources Inc | 60,022 | $552.2K | 0.00% | 00.0% | Unchanged |
| Acuta Capital Partners, LLC | 57,141 | $525.7K | 0.54% | −2,509−4.2% | Reduced |
| Susquehanna International Group, LLP | 53,571 | $492.9K | 0.00% | −45,919−46.2% | Reduced |
| HSBC Holdings PLC | 53,806 | $474.0K | 0.00% | +4,270+8.6% | Added |
| Fox Run Management, L.L.C. | 50,791 | $467.3K | 0.07% | +50,791 | New |
| Quest Partners LLC | 35,375 | $325.4K | 0.02% | +35,375 | New |
| Wells Fargo & Company | 32,507 | $299.1K | 0.00% | −1,241−3.7% | Reduced |
| Two Sigma Advisers, LP | 31,500 | $289.8K | 0.00% | −50,600−61.6% | Reduced |
| Graham Capital Management, L.P. | 30,486 | $280.5K | 0.01% | +18,434+153.0% | Added |
| Country Trust Bank | 30,041 | $276.4K | 0.01% | −145−0.5% | Reduced |
| LMR Partners LLP | 30,000 | $276.0K | 0.00% | −20,000−40.0% | Reduced |
| Prelude Capital Management, LLC | 28,832 | $265.3K | 0.02% | −114,297−79.9% | Reduced |
| Bailard, Inc. | 26,881 | $247.3K | 0.01% | 00.0% | Unchanged |
| MetLife Investment Management | 25,895 | $238.2K | 0.00% | −6,650−20.4% | Reduced |
| Quantinno Capital Management LP | 24,649 | $226.8K | 0.00% | +24,649 | New |
| PharVision Advisers, LLC | 23,868 | $219.6K | 0.12% | +23,868 | New |
| Trexquant Investment LP | 21,015 | $193.3K | 0.00% | +21,015 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 20,006 | $184.1K | 0.00% | −9,427−32.0% | Reduced |
| Matisse Capital | 18,630 | $171.4K | 0.08% | −7,470−28.6% | Reduced |
| JPMorgan Chase & Co | 18,069 | $166.2K | 0.00% | −8,093−30.9% | Reduced |
| Squarepoint Ops LLC | 17,826 | $164.0K | 0.00% | +4,151+30.4% | Added |
| Intech Investment Management LLC | 17,244 | $158.6K | 0.00% | −10,814−38.5% | Reduced |
| Algert Global LLC | 16,550 | $152.3K | 0.00% | +16,550 | New |
| Legal & General Group Plc | 16,373 | $150.6K | 0.00% | −1,088−6.2% | Reduced |
| Winton Group Ltd | 16,212 | $149.2K | 0.01% | +16,212 | New |
| Brevan Howard Capital Management LP | 15,303 | $140.8K | 0.00% | +15,303 | New |
| Creative Planning | 14,354 | $132.1K | 0.00% | −2,585−15.3% | Reduced |
| BNP Paribas Arbitrage, SA | 14,274 | $131.3K | 0.00% | +8,275+137.9% | Added |
| Alphabet Inc. | 14,262 | $131.2K | 0.01% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 13,948 | $128.3K | 0.00% | −5,939−29.9% | Reduced |
| Russell Investments Group, Ltd. | 13,731 | $126.3K | 0.00% | +4,423+47.5% | Added |
| State of Wisconsin Investment Board | 13,666 | $125.7K | 0.00% | +13,666 | New |
| JustInvest LLC | 13,168 | $121.1K | 0.00% | +225+1.7% | Added |
| Sanctuary Advisors, LLC | 13,154 | $121.0K | 0.00% | +13,154 | New |
| New York State Common Retirement Fund | 13,100 | $120.5K | 0.00% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 12,843 | $118.2K | 0.00% | +368+2.9% | Added |
| Simplex Trading, LLC | 12,800 | $117.0K | 0.00% | −96,565−88.3% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 11,272 | $103.7K | 0.00% | +11,272 | New |
| Martingale Asset Management L P | 10,563 | $97.2K | 0.00% | −80,452−88.4% | Reduced |
| Assetmark, Inc | 9,611 | $88.4K | 0.00% | +9,611 | New |
| FMR LLC | 7,350 | $67.6K | 0.00% | +383+5.5% | Added |
| Farther Finance Advisors, LLC | 7,112 | $65.4K | 0.00% | +3,697+108.3% | Added |