Fulcrum Therapeutics, Inc.
FULC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001680581
In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Fulcrum Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 129
- +8 vs. Q2 2025
- Shares held
- 53.8M
- −604.5K (−1.1%) vs. Q2 2025
- Total value
- $494.9M
- +$120.4M (+32.2%) vs. Q2 2025
- New holders
- 26
- 40 more added
- Sold out
- 18
- 43 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 154 | $291.3M |
| Q1 2026 | 169 | $550.1M |
| Q4 2025 | 172 | $762.7M |
| Q3 2025 | 129 | $494.9M |
| Q2 2025 | 122 | $374.5M |
| Q1 2025 | 117 | $147.8M |
| Q4 2024 | 119 | $243.4M |
| Q3 2024 | 130 | $196.4M |
| Q2 2024 | 121 | $402.0M |
| Q1 2024 | 126 | $569.7M |
| Q4 2023 | 101 | $412.3M |
| Q3 2023 | 81 | $250.4M |
| Q2 2023 | 88 | $183.2M |
| Q1 2023 | 116 | $172.2M |
| Q4 2022 | 110 | $368.5M |
| Q3 2022 | 105 | $422.1M |
| Q2 2022 | 102 | $196.6M |
| Q1 2022 | 108 | $929.9M |
| Q4 2021 | 110 | $657.3M |
| Q3 2021 | 101 | $1.03B |
| Q2 2021 | 67 | $280.8M |
| Q1 2021 | 68 | $317.0M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Essential Partners LLC | 1 | $9 | 0.00% | +1 | New |
| Clearstead Advisors, LLC | 4 | $37 | 0.00% | +4 | New |
| True Wealth Design, LLC | 16 | $148 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 28 | $258 | 0.00% | +2+7.7% | Added |
| Advisor Group Holdings, Inc. | 90 | $828 | 0.00% | 00.0% | Unchanged |
| Rialto Wealth Management, LLC | 159 | $1.46K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 204 | $1.88K | 0.00% | −14−6.4% | Reduced |
| CWM, LLC | 199 | $2.00K | 0.00% | +14+7.6% | Added |
| UMA Financial Services, Inc. | 283 | $2.60K | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 322 | $2.96K | 0.00% | +322 | New |
| Federated Hermes, Inc. | 328 | $3.02K | 0.00% | +328 | New |
| Rise Advisors, LLC | 348 | $3.20K | 0.00% | 00.0% | Unchanged |
| National Bank of Canada | 428 | $3.94K | 0.00% | −45−9.5% | Reduced |
| Citigroup Inc | 718 | $6.61K | 0.00% | −20,298−96.6% | Reduced |
| The PNC Financial Services Group, Inc. | 1,417 | $13.0K | 0.00% | −32−2.2% | Reduced |
| Versant Capital Management, Inc | 1,800 | $16.6K | 0.00% | +1,800 | New |
| Tower Research Capital LLC (TRC) | 1,910 | $17.6K | 0.00% | −4,467−70.0% | Reduced |
| IFP Advisors, Inc | 1,976 | $18.2K | 0.00% | +368+22.9% | Added |
| Amalgamated Bank | 2,147 | $20.0K | 0.00% | 00.0% | Unchanged |
| Macquarie Group Ltd | 2,495 | $23.0K | 0.00% | +2,495 | New |
| Sterling Capital Management LLC | 2,746 | $25.3K | 0.00% | +1,407+105.1% | Added |
| Clear Street Markets LLC | 2,917 | $26.8K | 0.01% | +2,917 | New |
| California State Teachers Retirement System | 3,334 | $30.7K | 0.00% | +2+0.1% | Added |
| Ameritas Investment Partners, Inc. | 3,598 | $33.1K | 0.00% | −2,481−40.8% | Reduced |
| Quarry LP | 3,774 | $34.7K | 0.01% | +3,774 | New |
| Nisa Investment Advisors, LLC | 4,281 | $39.4K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 5,760 | $53.0K | 0.00% | +141+2.5% | Added |
| BIT Capital GmbH | 6,090 | $56.0K | 0.00% | +1,258+26.0% | Added |
| Farther Finance Advisors, LLC | 7,112 | $65.4K | 0.00% | +3,697+108.3% | Added |
| FMR LLC | 7,350 | $67.6K | 0.00% | +383+5.5% | Added |
| Assetmark, Inc | 9,611 | $88.4K | 0.00% | +9,611 | New |
| Martingale Asset Management L P | 10,563 | $97.2K | 0.00% | −80,452−88.4% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 11,272 | $103.7K | 0.00% | +11,272 | New |
| Simplex Trading, LLC | 12,800 | $117.0K | 0.00% | −96,565−88.3% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 12,843 | $118.2K | 0.00% | +368+2.9% | Added |
| New York State Common Retirement Fund | 13,100 | $120.5K | 0.00% | 00.0% | Unchanged |
| Sanctuary Advisors, LLC | 13,154 | $121.0K | 0.00% | +13,154 | New |
| JustInvest LLC | 13,168 | $121.1K | 0.00% | +225+1.7% | Added |
| State of Wisconsin Investment Board | 13,666 | $125.7K | 0.00% | +13,666 | New |
| Russell Investments Group, Ltd. | 13,731 | $126.3K | 0.00% | +4,423+47.5% | Added |
| Manufacturers Life Insurance Company, The | 13,948 | $128.3K | 0.00% | −5,939−29.9% | Reduced |
| Alphabet Inc. | 14,262 | $131.2K | 0.01% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 14,274 | $131.3K | 0.00% | +8,275+137.9% | Added |
| Creative Planning | 14,354 | $132.1K | 0.00% | −2,585−15.3% | Reduced |
| Brevan Howard Capital Management LP | 15,303 | $140.8K | 0.00% | +15,303 | New |
| Winton Group Ltd | 16,212 | $149.2K | 0.01% | +16,212 | New |
| Legal & General Group Plc | 16,373 | $150.6K | 0.00% | −1,088−6.2% | Reduced |
| Algert Global LLC | 16,550 | $152.3K | 0.00% | +16,550 | New |
| Intech Investment Management LLC | 17,244 | $158.6K | 0.00% | −10,814−38.5% | Reduced |
| Squarepoint Ops LLC | 17,826 | $164.0K | 0.00% | +4,151+30.4% | Added |
| JPMorgan Chase & Co | 18,069 | $166.2K | 0.00% | −8,093−30.9% | Reduced |
| Matisse Capital | 18,630 | $171.4K | 0.08% | −7,470−28.6% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 20,006 | $184.1K | 0.00% | −9,427−32.0% | Reduced |
| Trexquant Investment LP | 21,015 | $193.3K | 0.00% | +21,015 | New |
| PharVision Advisers, LLC | 23,868 | $219.6K | 0.12% | +23,868 | New |
| Quantinno Capital Management LP | 24,649 | $226.8K | 0.00% | +24,649 | New |
| MetLife Investment Management | 25,895 | $238.2K | 0.00% | −6,650−20.4% | Reduced |
| Bailard, Inc. | 26,881 | $247.3K | 0.01% | 00.0% | Unchanged |
| Prelude Capital Management, LLC | 28,832 | $265.3K | 0.02% | −114,297−79.9% | Reduced |
| LMR Partners LLP | 30,000 | $276.0K | 0.00% | −20,000−40.0% | Reduced |
| Country Trust Bank | 30,041 | $276.4K | 0.01% | −145−0.5% | Reduced |
| Graham Capital Management, L.P. | 30,486 | $280.5K | 0.01% | +18,434+153.0% | Added |
| Two Sigma Advisers, LP | 31,500 | $289.8K | 0.00% | −50,600−61.6% | Reduced |
| Wells Fargo & Company | 32,507 | $299.1K | 0.00% | −1,241−3.7% | Reduced |
| Quest Partners LLC | 35,375 | $325.4K | 0.02% | +35,375 | New |
| Fox Run Management, L.L.C. | 50,791 | $467.3K | 0.07% | +50,791 | New |
| HSBC Holdings PLC | 53,806 | $474.0K | 0.00% | +4,270+8.6% | Added |
| Susquehanna International Group, LLP | 53,571 | $492.9K | 0.00% | −45,919−46.2% | Reduced |
| Acuta Capital Partners, LLC | 57,141 | $525.7K | 0.54% | −2,509−4.2% | Reduced |
| Franklin Resources Inc | 60,022 | $552.2K | 0.00% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 65,892 | $607.0K | 0.00% | −3,136−4.5% | Reduced |
| DekaBank Deutsche Girozentrale | 60,000 | $611.0K | 0.00% | 00.0% | Unchanged |
| Principal Financial Group Inc | 66,550 | $612.3K | 0.00% | +66,550 | New |
| Rhumbline Advisers | 69,372 | $638.2K | 0.00% | −13,878−16.7% | Reduced |
| Jacobs Levy Equity Management, Inc | 70,015 | $644.1K | 0.00% | −22,455−24.3% | Reduced |
| Alliancebernstein L.P. | 74,590 | $686.2K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 77,900 | $716.7K | 0.00% | +2,800+3.7% | Added |
| RBF Capital, LLC | 80,506 | $740.7K | 0.03% | 00.0% | Unchanged |
| Simplify Asset Management Inc. | 83,234 | $765.8K | 0.02% | +10,080+13.8% | Added |
| Commonwealth Equity Services, LLC | 83,428 | $768.0K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 89,616 | $824.5K | 0.00% | −22,447−20.0% | Reduced |
| Bridgeway Capital Management, LLC | 95,400 | $877.7K | 0.02% | −2,200−2.3% | Reduced |
| Exome Asset Management LLC | 98,799 | $909.0K | 0.60% | −346,150−77.8% | Reduced |
| Campbell & CO Investment Adviser LLC | 102,470 | $942.7K | 0.07% | +102,470 | New |
| Susquehanna Fundamental Investments, LLC | 111,582 | $1.03M | 0.04% | 00.0% | Unchanged |
| Nuveen, LLC | 112,203 | $1.03M | 0.00% | −12,520−10.0% | Reduced |
| Gsa Capital Partners LLP | 116,068 | $1.07M | 0.09% | +83,505+256.4% | Added |
| Bank of New York Mellon Corp | 119,158 | $1.10M | 0.00% | −17,842−13.0% | Reduced |
| Invesco Ltd. | 123,872 | $1.14M | 0.00% | −346,461−73.7% | Reduced |
| Ameriprise Financial Inc | 124,666 | $1.15M | 0.00% | +124,666 | New |
| HRT Financial LP | 124,924 | $1.15M | 0.00% | +124,924 | New |
| J. Goldman & Co LP | 135,000 | $1.24M | 0.05% | +67,500+100.0% | Added |
| Fiduciary Trust Co | 136,555 | $1.26M | 0.01% | 00.0% | Unchanged |
| Standard Life Aberdeen plc | 137,961 | $1.27M | 0.00% | +79,265+135.0% | Added |
| Bank of America Corp | 147,211 | $1.35M | 0.00% | +101,222+220.1% | Added |
| Millennium Management LLC | 150,867 | $1.39M | 0.00% | +45,174+42.7% | Added |
| American Century Companies Inc | 152,244 | $1.40M | 0.00% | +19,895+15.0% | Added |
| Wellington Management Group LLP | 179,358 | $1.65M | 0.00% | +52,956+41.9% | Added |
| Braidwell LP | 219,488 | $2.02M | 0.06% | +219,488 | New |
| Morgan Stanley | 243,835 | $2.24M | 0.00% | −70,575−22.4% | Reduced |