Fulcrum Therapeutics, Inc.

FULC

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001680581

SEC filings (opens in a new tab)

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

Q3 2025 vs. Q2 2025

How the institutions holding Fulcrum Therapeutics, Inc. changed between Q2 2025 and Q3 2025.

All holders in Q3 2025 All holders in Q2 2025

13F holders of FULC: Q2 2025 compared with Q3 2025
Measure	Q2 2025	Of which not filed for Q3 2025	Q3 2025	Change
Holders	122	1	129	+8
Shares	54.4M	5.00K	53.8M	−604.5K (−1.1%)
Value	$374.5M	$34.0K	$494.9M	+$120.4M (+32.2%)

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (26)

Institutions that held Fulcrum Therapeutics, Inc. at the end of Q3 2025 but not at the end of Q2 2025.

Institutions new to FULC in Q3 2025
Institution	Shares	Value	% of portfolio
Braidwell LP	219,488	$2.02M	0.06%
HRT Financial LP	124,924	$1.15M	0.00%
Ameriprise Financial Inc	124,666	$1.15M	0.00%
Campbell & CO Investment Adviser LLC	102,470	$942.7K	0.07%
Principal Financial Group Inc	66,550	$612.3K	0.00%
Fox Run Management, L.L.C.	50,791	$467.3K	0.07%
Quest Partners LLC	35,375	$325.4K	0.02%
Quantinno Capital Management LP	24,649	$226.8K	0.00%
PharVision Advisers, LLC	23,868	$219.6K	0.12%
Trexquant Investment LP	21,015	$193.3K	0.00%
Algert Global LLC	16,550	$152.3K	0.00%
Winton Group Ltd	16,212	$149.2K	0.01%
Brevan Howard Capital Management LP	15,303	$140.8K	0.00%
State of Wisconsin Investment Board	13,666	$125.7K	0.00%
Sanctuary Advisors, LLC	13,154	$121.0K	0.00%
Y-Intercept (Hong Kong) Ltd	11,272	$103.7K	0.00%
Assetmark, Inc	9,611	$88.4K	0.00%
Quarry LP	3,774	$34.7K	0.01%
Clear Street Markets LLC	2,917	$26.8K	0.01%
Macquarie Group Ltd	2,495	$23.0K	0.00%
Versant Capital Management, Inc	1,800	$16.6K	0.00%
Federated Hermes, Inc.	328	$3.02K	0.00%
Optiver Holding B.V.	322	$2.96K	0.00%
Clearstead Advisors, LLC	4	$37	0.00%
Essential Partners LLC	1	$9	0.00%
Summit Wealth Group LLC	533	–	–

Sold out (18)

Institutions that held Fulcrum Therapeutics, Inc. at the end of Q2 2025 and filed for Q3 2025 without it.

Institutions that sold out of FULC in Q3 2025
Institution	Shares, Q2 2025	Value, Q2 2025
Woodline Partners LP	897,617	$6.18M
Point72 Asset Management, L.P.	498,219	$3.43M
Catalio Capital Management, LP	188,304	$1.30M
Two Sigma Investments, LP	58,965	$405.7K
Integrated Quantitative Investments LLC	41,106	$282.8K
Allostery Investments LP	40,353	$277.6K
PDT Partners, LLC	27,280	$187.7K
Sherbrooke Park Advisers LLC	27,201	$187.1K
AQR Capital Management LLC	18,053	$124.2K
Evergreen Capital Management LLC	16,502	$113.5K
Voya Investment Management LLC	15,411	$106.0K
Prudential Financial Inc	14,540	$100.0K
Los Angeles Capital Management LLC	13,465	$92.6K
ProShare Advisors LLC	10,951	$75.3K
Skopos Labs, Inc.	6,281	$43.2K
Point72 Asia (Singapore) Pte. Ltd.	3,031	$20.9K
Point72 (DIFC) Ltd	2,665	$18.3K
US Bancorp	1,911	$13.1K

Not filed for Q3 2025 yet (1)

Institutions that held Fulcrum Therapeutics, Inc. at the end of Q2 2025 and haven't filed a 13F for Q3 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding FULC in Q2 2025 that haven't filed for Q3 2025
Institution	Shares, Q2 2025	Value, Q2 2025
PrairieView Partners, LLC	5,000	$34.0K