Fulcrum Therapeutics, Inc.
FULC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001680581
In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Fulcrum Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 122
- +5 vs. Q1 2025
- Shares held
- 54.4M
- +3.03M (+5.9%) vs. Q1 2025
- Total value
- $374.5M
- +$226.7M (+153.4%) vs. Q1 2025
- New holders
- 24
- 34 more added
- Sold out
- 19
- 46 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 154 | $291.3M |
| Q1 2026 | 169 | $550.1M |
| Q4 2025 | 172 | $762.7M |
| Q3 2025 | 129 | $494.9M |
| Q2 2025 | 122 | $374.5M |
| Q1 2025 | 117 | $147.8M |
| Q4 2024 | 119 | $243.4M |
| Q3 2024 | 130 | $196.4M |
| Q2 2024 | 121 | $402.0M |
| Q1 2024 | 126 | $569.7M |
| Q4 2023 | 101 | $412.3M |
| Q3 2023 | 81 | $250.4M |
| Q2 2023 | 88 | $183.2M |
| Q1 2023 | 116 | $172.2M |
| Q4 2022 | 110 | $368.5M |
| Q3 2022 | 105 | $422.1M |
| Q2 2022 | 102 | $196.6M |
| Q1 2022 | 108 | $929.9M |
| Q4 2021 | 110 | $657.3M |
| Q3 2021 | 101 | $1.03B |
| Q2 2021 | 67 | $280.8M |
| Q1 2021 | 68 | $317.0M |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 10,229,099 | $70.4M | 1.19% | 00.0% | Unchanged |
| TCG Crossover Management, LLC | 5,250,000 | $36.1M | 4.13% | 00.0% | Unchanged |
| Suvretta Capital Management, LLC | 5,082,900 | $35.0M | 1.32% | +15,506+0.3% | Added |
| Adage Capital Partners GP, L.L.C. | 4,589,000 | $31.6M | 0.05% | +1,589,000+53.0% | Added |
| BlackRock, Inc. | 4,379,023 | $30.1M | 0.00% | −331,674−7.0% | Reduced |
| Nantahala Capital Management, LLC | 4,288,299 | $29.5M | 2.09% | −534,394−11.1% | Reduced |
| Vanguard Group Inc | 3,146,443 | $21.6M | 0.00% | −73,935−2.3% | Reduced |
| Dimensional Fund Advisors LP | 1,372,637 | $9.44M | 0.00% | −34,412−2.4% | Reduced |
| Balyasny Asset Management LLC | 1,338,214 | $9.21M | 0.02% | +1,338,214 | New |
| State Street Corp | 1,218,366 | $8.38M | 0.00% | −34,074−2.7% | Reduced |
| Geode Capital Management, LLC | 1,193,138 | $8.21M | 0.00% | −38,237−3.1% | Reduced |
| D. E. Shaw & Co., Inc. | 1,176,711 | $8.10M | 0.01% | +596,050+102.7% | Added |
| Goldman Sachs Group Inc | 1,143,536 | $7.87M | 0.00% | +740,936+184.0% | Added |
| Woodline Partners LP | 897,617 | $6.18M | 0.03% | 00.0% | Unchanged |
| Northern Trust Corp | 611,536 | $4.21M | 0.00% | −29,411−4.6% | Reduced |
| Acadian Asset Management LLC | 563,380 | $3.87M | 0.01% | +218,819+63.5% | Added |
| Point72 Asset Management, L.P. | 498,219 | $3.43M | 0.01% | +498,219 | New |
| Invesco Ltd. | 470,333 | $3.24M | 0.00% | +384,566+448.4% | Added |
| Exome Asset Management LLC | 444,949 | $3.06M | 2.52% | −244,188−35.4% | Reduced |
| Ikarian Capital, LLC | 428,521 | $2.95M | 0.98% | +228,425+114.2% | Added |
| Charles Schwab Investment Management Inc | 387,782 | $2.67M | 0.00% | +6,423+1.7% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 342,547 | $2.36M | 0.01% | +124,798+57.3% | Added |
| Morgan Stanley | 314,410 | $2.16M | 0.00% | +28,811+10.1% | Added |
| Bessemer Group Inc | 286,988 | $1.98M | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 279,251 | $1.92M | 0.00% | −561−0.2% | Reduced |
| Schonfeld Strategic Advisors LLC | 204,400 | $1.41M | 0.01% | +204,400 | New |
| Catalio Capital Management, LP | 188,304 | $1.30M | 0.27% | −13,835−6.8% | Reduced |
| Citadel Advisors LLC | 166,234 | $1.14M | 0.00% | −208,022−55.6% | Reduced |
| Prelude Capital Management, LLC | 143,129 | $984.7K | 0.10% | −49,078−25.5% | Reduced |
| Boothbay Fund Management, LLC | 141,378 | $972.7K | 0.03% | +81,845+137.5% | Added |
| Bank of New York Mellon Corp | 137,000 | $942.6K | 0.00% | −6,588−4.6% | Reduced |
| Fiduciary Trust Co | 136,555 | $939.5K | 0.01% | 00.0% | Unchanged |
| UBS Group AG | 135,205 | $930.2K | 0.00% | +63,285+88.0% | Added |
| American Century Companies Inc | 132,349 | $910.6K | 0.00% | +8,638+7.0% | Added |
| Wellington Management Group LLP | 126,402 | $869.6K | 0.00% | +126,402 | New |
| Nuveen, LLC | 124,723 | $858.1K | 0.00% | −28,269−18.5% | Reduced |
| Barclays PLC | 112,063 | $771.0K | 0.00% | +29,606+35.9% | Added |
| Susquehanna Fundamental Investments, LLC | 111,582 | $767.7K | 0.02% | −39,061−25.9% | Reduced |
| Simplex Trading, LLC | 109,365 | $752.0K | 0.02% | +106,339+3,514.2% | Added |
| Millennium Management LLC | 105,693 | $727.2K | 0.00% | +65,001+159.7% | Added |
| Susquehanna International Group, LLP | 99,490 | $684.5K | 0.00% | +34,650+53.4% | Added |
| Bridgeway Capital Management, LLC | 97,600 | $671.5K | 0.02% | 00.0% | Unchanged |
| Jacobs Levy Equity Management, Inc | 92,470 | $636.2K | 0.00% | −55,184−37.4% | Reduced |
| Martingale Asset Management L P | 91,015 | $626.2K | 0.02% | +91,015 | New |
| DekaBank Deutsche Girozentrale | 60,000 | $616.0K | 0.00% | 00.0% | Unchanged |
| Commonwealth Equity Services, LLC | 83,428 | $574.0K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 83,250 | $572.8K | 0.00% | −5,743−6.5% | Reduced |
| Two Sigma Advisers, LP | 82,100 | $564.8K | 0.00% | −195,700−70.4% | Reduced |
| RBF Capital, LLC | 80,506 | $553.9K | 0.03% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 78,500 | $540.1K | 0.00% | −322,600−80.4% | Reduced |
| STRS Ohio | 75,100 | $516.7K | 0.00% | −16,100−17.7% | Reduced |
| Alliancebernstein L.P. | 74,590 | $513.2K | 0.00% | +9,000+13.7% | Added |
| Simplify Asset Management Inc. | 73,154 | $503.3K | 0.03% | −7,980−9.8% | Reduced |
| Price T Rowe Associates Inc | 69,028 | $475.0K | 0.00% | −1,140−1.6% | Reduced |
| J. Goldman & Co LP | 67,500 | $464.4K | 0.01% | +47,250+233.3% | Added |
| Franklin Resources Inc | 60,022 | $413.0K | 0.00% | +35,201+141.8% | Added |
| Acuta Capital Partners, LLC | 59,650 | $410.4K | 0.57% | +59,650 | New |
| Two Sigma Investments, LP | 58,965 | $405.7K | 0.00% | −91,309−60.8% | Reduced |
| Standard Life Aberdeen plc | 58,696 | $403.8K | 0.00% | +58,696 | New |
| ADAR1 Capital Management, LLC | 53,349 | $367.0K | 0.06% | −437,183−89.1% | Reduced |
| HSBC Holdings PLC | 49,536 | $356.9K | 0.00% | −25,425−33.9% | Reduced |
| LMR Partners LLP | 50,000 | $344.0K | 0.01% | +50,000 | New |
| Bank of America Corp | 45,989 | $316.4K | 0.00% | −10,146−18.1% | Reduced |
| Integrated Quantitative Investments LLC | 41,106 | $282.8K | 0.08% | +41,106 | New |
| Allostery Investments LP | 40,353 | $277.6K | 3.54% | +40,353 | New |
| Wells Fargo & Company | 33,748 | $232.2K | 0.00% | +3,228+10.6% | Added |
| Gsa Capital Partners LLP | 32,563 | $224.0K | 0.02% | +32,563 | New |
| MetLife Investment Management | 32,545 | $223.9K | 0.00% | +15,010+85.6% | Added |
| Country Trust Bank | 30,186 | $207.7K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 29,433 | $202.5K | 0.00% | −2,159−6.8% | Reduced |
| Intech Investment Management LLC | 28,058 | $193.0K | 0.00% | −17,631−38.6% | Reduced |
| PDT Partners, LLC | 27,280 | $187.7K | 0.01% | +27,280 | New |
| Sherbrooke Park Advisers LLC | 27,201 | $187.1K | 0.08% | −28,141−50.8% | Reduced |
| Bailard, Inc. | 26,881 | $184.9K | 0.00% | +26,881 | New |
| JPMorgan Chase & Co | 26,162 | $180.0K | 0.00% | −183,731−87.5% | Reduced |
| Matisse Capital | 26,100 | $179.6K | 0.08% | −70,617−73.0% | Reduced |
| Citigroup Inc | 21,016 | $144.6K | 0.00% | −16,813−44.4% | Reduced |
| Manufacturers Life Insurance Company, The | 19,887 | $136.8K | 0.00% | −2,524−11.3% | Reduced |
| AQR Capital Management LLC | 18,053 | $124.2K | 0.00% | +445+2.5% | Added |
| Legal & General Group Plc | 17,461 | $120.1K | 0.00% | +12,173+230.2% | Added |
| Jane Street Group, LLC | 17,427 | $119.9K | 0.00% | −100,389−85.2% | Reduced |
| Creative Planning | 16,939 | $116.5K | 0.00% | +16,939 | New |
| Evergreen Capital Management LLC | 16,502 | $113.5K | 0.00% | +16,502 | New |
| Voya Investment Management LLC | 15,411 | $106.0K | 0.00% | −3,137−16.9% | Reduced |
| Prudential Financial Inc | 14,540 | $100.0K | 0.00% | −8,185−36.0% | Reduced |
| Alphabet Inc. | 14,262 | $98.1K | 0.00% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 13,675 | $94.1K | 0.00% | +13,675 | New |
| Los Angeles Capital Management LLC | 13,465 | $92.6K | 0.00% | +13,465 | New |
| New York State Common Retirement Fund | 13,100 | $90.1K | 0.00% | 00.0% | Unchanged |
| JustInvest LLC | 12,943 | $89.0K | 0.00% | +2,677+26.1% | Added |
| Police & Firemen's Retirement System of New Jersey | 12,475 | $85.8K | 0.00% | 00.0% | Unchanged |
| Graham Capital Management, L.P. | 12,052 | $82.9K | 0.00% | −154,191−92.8% | Reduced |
| ProShare Advisors LLC | 10,951 | $75.3K | 0.00% | −706−6.1% | Reduced |
| Russell Investments Group, Ltd. | 9,308 | $64.0K | 0.00% | +9,092+4,209.3% | Added |
| FMR LLC | 6,967 | $47.9K | 0.00% | +2,649+61.3% | Added |
| Tower Research Capital LLC (TRC) | 6,377 | $43.9K | 0.00% | −1,955−23.5% | Reduced |
| Skopos Labs, Inc. | 6,281 | $43.2K | 0.01% | −5,909−48.5% | Reduced |
| Ameritas Investment Partners, Inc. | 6,079 | $41.8K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 5,999 | $41.3K | 0.00% | −9,587−61.5% | Reduced |
| Group One Trading, L.P. | 5,619 | $38.7K | 0.00% | −1,173−17.3% | Reduced |