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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Fulcrum Therapeutics, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
121
−5 vs. Q1 2024
Shares held
64.8M
+4.43M (+7.3%) vs. Q1 2024
Total value
$402.0M
−$167.7M (−29.4%) vs. Q1 2024
New holders
31
46 more added
Sold out
36
25 more reduced

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 121 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ2 2024: $402.0M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q1 2024.

Institutions holding FULC in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.11,609,704$72.0M0.95%00.0%Unchanged
RTW Investments, LP5,845,956$36.2M0.56%00.0%Unchanged
FMR LLC5,329,946$33.0M0.00%−34,719−0.6%Reduced
BlackRock Inc.4,798,522$29.8M0.00%+3,257,313+211.3%Added
Vanguard Group Inc3,071,143$19.0M0.00%+532,478+21.0%Added
Cowen and Company, LLC2,964,127$18.4M0.51%−749,807−20.2%Reduced
Suvretta Capital Management, LLC2,541,046$15.8M0.64%−307,440−10.8%Reduced
TRV GP IV, LLC2,343,154$14.5M7.18%00.0%Unchanged
Citadel Advisors LLC1,777,112$11.0M0.01%+451,733+34.1%Added
Dimensional Fund Advisors LP1,480,926$9.18M0.00%+176,114+13.5%Added
MPM Oncology Impact Management LP1,444,851$8.96M1.39%+307,743+27.1%Added
Jefferies Financial Group Inc.1,433,316$8.89M0.17%+281,590+24.4%Added
Geode Capital Management, LLC1,307,377$8.11M0.00%+743,919+132.0%Added
Morgan Stanley1,234,813$7.66M0.00%+77,676+6.7%Added
Vestal Point Capital, LP1,160,000$7.19M0.54%+465,000+66.9%Added
State Street Corp1,041,274$6.46M0.00%+784,413+305.4%Added
Deutsche Bank AG849,193$5.26M0.00%+26,095+3.2%Added
Propel Bio Management, LLC750,000$4.65M3.02%00.0%Unchanged
Rock Springs Capital Management LP727,673$4.51M0.14%00.0%Unchanged
StemPoint Capital LP696,464$4.32M1.27%+289,356+71.1%Added
Simplify Asset Management Inc.674,832$4.18M0.37%−1,199−0.2%Reduced
D. E. Shaw & Co., Inc.591,785$3.67M0.01%−33,391−5.3%Reduced
Two Sigma Advisers, LP563,500$3.49M0.01%+143,300+34.1%Added
Goldman Sachs Group Inc560,492$3.48M0.00%−249,778−30.8%Reduced
Qube Research & Technologies Ltd553,307$3.43M0.01%−169,856−23.5%Reduced
Caption Management, LLC525,300$3.26M0.35%+209,840+66.5%Added
Two Sigma Investments, LP509,688$3.16M0.01%+334,464+190.9%Added
Woodline Partners LP501,301$3.11M0.03%+501,301New
Assenagon Asset Management S.A.497,456$3.08M0.01%+497,456New
Millennium Management LLC402,749$2.50M0.00%−494,712−55.1%Reduced
Silverarc Capital Management, LLC398,436$2.47M0.61%00.0%Unchanged
ADAR1 Capital Management, LLC368,369$2.28M0.46%+28,544+8.4%Added
Marshall Wace, LLP333,161$2.07M0.00%+107,588+47.7%Added
Exome Asset Management LLC302,700$1.88M1.67%+302,700New
Adage Capital Partners GP, L.L.C.300,000$1.86M0.00%−806,422−72.9%Reduced
Bessemer Group Inc286,988$1.78M0.00%00.0%Unchanged
Opaleye Management Inc.285,000$1.77M0.40%+155,000+119.2%Added
Standard Life Aberdeen plc256,888$1.59M0.00%00.0%Unchanged
Alliancebernstein L.P.222,982$1.38M0.00%+36,017+19.3%Added
Mass General Brigham, Inc205,356$1.27M6.20%00.0%Unchanged
Alyeska Investment Group, L.P.202,148$1.25M0.01%00.0%Unchanged
UBS Group AG190,551$1.18M0.00%+117,783+161.9%Added
Bank of New York Mellon Corp186,727$1.16M0.00%+186,727New
Wellington Management Group LLP182,729$1.13M0.00%+10,069+5.8%Added
Charles Schwab Investment Management Inc175,983$1.09M0.00%+151,498+618.7%Added
Nuveen Asset Management, LLC169,549$1.05M0.00%+169,549New
Jane Street Group, LLC168,244$1.04M0.00%−366,818−68.6%Reduced
Northern Trust Corp166,894$1.03M0.00%+30,461+22.3%Added
Eversept Partners, LP152,965$948.4K0.07%+152,965New
ExodusPoint Capital Management, LP150,505$933.0K0.01%+129,086+602.7%Added
Fiduciary Trust Co136,555$846.6K0.01%00.0%Unchanged
Gsa Capital Partners LLP135,221$838.0K0.06%+120,059+791.8%Added
RBF Capital, LLC125,000$775.0K0.05%−15,000−10.7%Reduced
American Century Companies Inc104,371$647.1K0.00%+12,167+13.2%Added
Jump Financial, LLC94,181$583.9K0.01%+63,337+205.3%Added
DekaBank Deutsche Girozentrale60,000$568.0K0.00%00.0%Unchanged
Rhumbline Advisers91,432$566.9K0.00%+89,775+5,417.9%Added
Stifel Financial Corp87,607$543.2K0.00%+2,593+3.1%Added
Commonwealth Equity Services, LLC84,428$523.0K0.00%+1,000+1.2%Added
Susquehanna International Group, LLP81,595$505.9K0.00%−479,397−85.5%Reduced
Susquehanna Portfolio Strategies, LLC81,217$503.5K0.02%−87,558−51.9%Reduced
Trexquant Investment LP70,506$437.1K0.01%+23,284+49.3%Added
Bank of America Corp69,886$433.3K0.00%+8,233+13.4%Added
Alpine Global Management, LLC59,983$371.9K0.06%+59,983New
Group One Trading, L.P.59,395$368.2K0.01%+38,542+184.8%Added
Simplex Trading, LLC57,133$354.0K0.01%+26,394+85.9%Added
Alps Advisors Inc48,479$300.6K0.00%+4,797+11.0%Added
Algert Global LLC41,303$256.1K0.01%+27,633+202.1%Added
Price T Rowe Associates Inc35,712$222.0K0.00%+19,812+124.6%Added
Corebridge Financial, Inc.33,383$207.3K0.00%+33,383New
JPMorgan Chase & Co33,041$204.9K0.00%−125,894−79.2%Reduced
Bank of Montreal32,282$204.3K0.00%+32,282New
Invesco Ltd.31,043$192.5K0.00%−465,636−93.7%Reduced
Country Trust Bank30,186$187.2K0.00%00.0%Unchanged
Prelude Capital Management, LLC28,100$174.2K0.01%+28,100New
Semanteon Capital Management, LP26,658$165.3K0.12%+26,658New
Barclays PLC26,576$164.8K0.00%−44,939−62.8%Reduced
Corton Capital Inc.26,172$162.3K0.09%+13,719+110.2%Added
Quest Partners LLC26,164$162.2K0.02%+26,164New
SG Americas Securities, LLC26,093$162.0K0.00%+13,887+113.8%Added
Brandywine Managers, LLC26,127$162.0K0.17%00.0%Unchanged
Wells Fargo & Company25,120$155.7K0.00%+24,733+6,391.0%Added
New York State Common Retirement Fund25,100$155.6K0.00%+25,100New
Franklin Resources Inc24,821$153.9K0.00%00.0%Unchanged
Squarepoint Ops LLC24,517$152.0K0.00%−30,043−55.1%Reduced
Manufacturers Life Insurance Company, The24,480$151.8K0.00%+24,480New
Citigroup Inc22,791$141.3K0.00%−155,773−87.2%Reduced
Voya Investment Management LLC21,154$131.2K0.00%+21,154New
Los Angeles Capital Management LLC21,038$130.4K0.00%+21,038New
Engineers Gate Manager LP19,860$123.1K0.00%+19,860New
Aigen Investment Management, LP19,311$119.7K0.02%+19,311New
Caxton Associates LP18,875$117.0K0.00%+18,875New
Aquatic Capital Management LLC17,300$107.3K0.00%+8,300+92.2%Added
Tower Research Capital LLC (TRC)16,324$101.2K0.00%+6,473+65.7%Added
MetLife Investment Management15,898$98.6K0.00%+15,898New
Alphabet Inc.14,262$88.4K0.00%00.0%Unchanged
Quantbot Technologies LP14,029$87.0K0.00%+14,029New
Renaissance Technologies LLC13,257$82.2K0.00%+13,257New
Virtus ETF Advisers LLC11,606$72.0K0.04%+11,606New
Balyasny Asset Management LLC11,367$70.5K0.00%−4,342−27.6%Reduced