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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q3 2023

Institutional positions in Fulcrum Therapeutics, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
81
−6 vs. Q2 2023
Shares held
56.4M
+1.13M (+2.0%) vs. Q2 2023
Total value
$250.4M
+$68.0M (+37.3%) vs. Q2 2023
New holders
15
17 more added
Sold out
21
26 more reduced

1 institution that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 81 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ3 2023: $250.4M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q2 2023.

Institutions holding FULC in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.11,609,704$51.5M1.01%00.0%Unchanged
FMR LLC5,975,416$26.5M0.00%+421,676+7.6%Added
RTW Investments, LP5,818,804$25.8M0.55%−245,319−4.0%Reduced
Suvretta Capital Management, LLC5,718,881$25.4M1.37%00.0%Unchanged
Cowen and Company, LLC4,308,359$19.1M1.34%+1,191,363+38.2%Added
Vanguard Group Inc2,643,195$11.7M0.00%+17,166+0.7%Added
Adage Capital Partners GP, L.L.C.2,406,422$10.7M0.02%+100,000+4.3%Added
TRV GP IV, LLC2,343,154$10.4M3.92%00.0%Unchanged
BlackRock Inc.1,445,938$6.42M0.00%−68,487−4.5%Reduced
Jefferies Financial Group Inc.1,433,316$6.36M0.16%+1,433,316New
Citadel Advisors LLC1,254,184$5.57M0.01%−250,455−16.6%Reduced
Marshall Wace, LLP1,048,646$4.66M0.01%+1,031,246+5,926.7%Added
Millennium Management LLC1,004,682$4.46M0.00%+429,825+74.8%Added
Morgan Stanley911,871$4.05M0.00%−192,003−17.4%Reduced
Rock Springs Capital Management LP727,673$3.23M0.09%00.0%Unchanged
Simplify Asset Management Inc.570,519$2.53M0.42%−125,777−18.1%Reduced
Two Sigma Investments, LP562,123$2.50M0.01%−15,743−2.7%Reduced
Dimensional Fund Advisors LP561,998$2.50M0.00%+86,663+18.2%Added
Geode Capital Management, LLC534,503$2.37M0.00%−31,306−5.5%Reduced
Two Sigma Advisers, LP522,000$2.32M0.01%−73,300−12.3%Reduced
Vivo Capital, LLC520,000$2.31M0.29%−30,000−5.5%Reduced
Susquehanna International Group, LLP505,341$2.24M0.00%+258,113+104.4%Added
Bessemer Group Inc286,988$1.27M0.00%00.0%Unchanged
Jacobs Levy Equity Management, Inc265,506$1.18M0.01%+265,506New
Goldman Sachs Group Inc259,227$1.15M0.00%−128,505−33.1%Reduced
Alliancebernstein L.P.233,538$1.04M0.00%+233,538New
D. E. Shaw & Co., Inc.221,264$982.4K0.00%+75,042+51.3%Added
Alyeska Investment Group, L.P.202,148$897.5K0.01%00.0%Unchanged
Hudson Bay Capital Management LP196,488$872.4K0.01%+196,488New
State Street Corp183,147$813.2K0.00%−22,800−11.1%Reduced
RBF Capital, LLC154,100$684.2K0.05%00.0%Unchanged
Northern Trust Corp142,981$634.8K0.00%−446−0.3%Reduced
Bank of America Corp139,044$617.4K0.00%+6,806+5.1%Added
Fiduciary Trust Co136,555$606.3K0.01%00.0%Unchanged
Acuitas Investments, LLC134,811$598.6K0.35%−40.0%Reduced
Bridgeway Capital Management, LLC126,500$561.7K0.01%00.0%Unchanged
ClariVest Asset Management LLC104,400$464.0K0.03%+104,400New
Jump Financial, LLC91,790$407.5K0.02%+91,790New
Citigroup Inc89,189$396.0K0.00%+81,286+1,028.5%Added
Occudo Quantitative Strategies LP87,372$387.9K0.05%+87,372New
Denali Advisors LLC70,600$313.5K0.11%+70,600New
Bank of New York Mellon Corp61,190$271.7K0.00%−1,132−1.8%Reduced
DekaBank Deutsche Girozentrale60,000$268.0K0.00%+60,000New
Squarepoint Ops LLC58,900$261.5K0.00%−41,891−41.6%Reduced
Renaissance Technologies LLC52,734$234.0K0.00%−292,076−84.7%Reduced
MYDA Advisors LLC50,000$222.0K0.08%00.0%Unchanged
XTX Topco Ltd38,918$172.8K0.03%−44,248−53.2%Reduced
Jane Street Group, LLC38,501$170.9K0.00%−27,792−41.9%Reduced
American Century Companies Inc36,939$164.0K0.00%+8,522+30.0%Added
Algert Global LLC31,010$137.7K0.01%+31,010New
Country Trust Bank30,186$134.0K0.00%00.0%Unchanged
Franklin Resources Inc28,356$125.9K0.00%00.0%Unchanged
Landscape Capital Management, L.L.C.28,252$125.4K0.02%+28,252New
Marquette Asset Management, LLC27,867$123.7K0.03%00.0%Unchanged
Stifel Financial Corp27,688$122.9K0.00%+2,200+8.6%Added
Brandywine Managers, LLC26,127$116.0K0.20%00.0%Unchanged
Simplex Trading, LLC25,424$112.0K0.00%+24,976+5,575.0%Added
Brown Wealth Management, LLC25,000$111.0K0.05%+25,000New
Charles Schwab Investment Management Inc24,485$108.7K0.00%00.0%Unchanged
Blackstone Group Inc.19,216$85.3K0.00%00.0%Unchanged
Verition Fund Management LLC19,212$85.3K0.00%−40,337−67.7%Reduced
Principal Financial Group Inc18,749$83.2K0.00%+1,687+9.9%Added
Price T Rowe Associates Inc15,900$71.0K0.00%−5,300−25.0%Reduced
Alphabet Inc.14,262$63.3K0.00%00.0%Unchanged
Qube Research & Technologies Ltd13,066$58.0K0.00%+13,066New
Graham Capital Management, L.P.11,845$52.6K0.00%−20,103−62.9%Reduced
UBS Group AG11,157$49.5K0.00%−20,602−64.9%Reduced
JPMorgan Chase & Co10,899$48.4K0.00%+9,585+729.5%Added
Centiva Capital, LP10,747$47.7K0.00%+10,747New
Group One Trading, L.P.6,773$30.1K0.00%+6,773New
Tower Research Capital LLC (TRC)5,247$23.3K0.00%−5,773−52.4%Reduced
PrairieView Partners, LLC5,000$22.0K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)2,023$8.98K0.00%−668−24.8%Reduced
Rhumbline Advisers1,657$7.36K0.00%−3,134−65.4%Reduced
China Universal Asset Management Co., Ltd.1,594$7.08K0.00%+784+96.8%Added
Nisa Investment Advisors, LLC1,542$6.85K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC790$3.51K0.00%00.0%Unchanged
National Bank of Canada460$1.86K0.00%00.0%Unchanged
Wells Fargo & Company361$1.60K0.00%−604−62.6%Reduced
Daiwa Securities Group Inc.138$1.00K0.00%00.0%Unchanged
Royal Bank of Canada10$00.00%00.0%Unchanged
Point72 Asset Management, L.P.0$00.00%−1,899,968−100.0%Sold out
Woodline Partners LP0$00.00%−596,695−100.0%Sold out
Harvard Management Co Inc0$00.00%−341,972−100.0%Sold out
Barclays PLC0$00.00%−144,983−100.0%Sold out
Opaleye Management Inc.0$00.00%−143,600−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−117,000−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−61,587−100.0%Sold out
Ergoteles LLC0$00.00%−40,800−100.0%Sold out
Laurion Capital Management LP0$00.00%−33,645−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−32,760−100.0%Sold out
Point72 Middle East FZE0$00.00%−32,145−100.0%Sold out
Old Mission Capital LLC0$00.00%−23,900−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−22,594−100.0%Sold out
UBS Asset Management Americas Inc0$00.00%−25,699−100.0%Sold out
Nantahala Capital Management, LLC0$00.00%−21,370−100.0%Sold out
Quantamental Technologies LLC0$00.00%−11,855−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−11,171−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−11,087−100.0%Sold out
DRW Securities, LLC0$00.00%−11,000−100.0%Sold out