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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Fulcrum Therapeutics, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
126
+25 vs. Q4 2023
Shares held
60.4M
−705.2K (−1.2%) vs. Q4 2023
Total value
$569.7M
+$157.4M (+38.2%) vs. Q4 2023
New holders
36
33 more added
Sold out
11
29 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 126 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ1 2024: $569.7M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q4 2023.

Institutions holding FULC in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.11,609,704$109.6M1.39%00.0%Unchanged
RTW Investments, LP5,845,956$55.2M0.81%+376,000+6.9%Added
FMR LLC5,364,665$50.6M0.00%−319,950−5.6%Reduced
Cowen and Company, LLC3,713,934$35.1M1.37%+240,000+6.9%Added
Suvretta Capital Management, LLC2,848,486$26.9M1.13%−2,670,395−48.4%Reduced
Vanguard Group Inc2,538,665$24.0M0.00%+18,681+0.7%Added
TRV GP IV, LLC2,343,154$22.1M10.72%00.0%Unchanged
BlackRock Inc.1,541,209$14.5M0.00%−20,657−1.3%Reduced
Citadel Advisors LLC1,325,379$12.5M0.01%−78,494−5.6%Reduced
Dimensional Fund Advisors LP1,304,812$12.3M0.00%+329,533+33.8%Added
Morgan Stanley1,157,137$10.9M0.00%−61,922−5.1%Reduced
Jefferies Financial Group Inc.1,151,726$10.9M0.22%−281,590−19.6%Reduced
MPM Oncology Impact Management LP1,137,108$10.7M1.73%+1,137,108New
Adage Capital Partners GP, L.L.C.1,106,422$10.4M0.02%−400,000−26.6%Reduced
Millennium Management LLC897,461$8.47M0.01%+459,958+105.1%Added
Deutsche Bank AG823,098$7.77M0.00%00.0%Unchanged
Goldman Sachs Group Inc810,270$7.65M0.00%−61,233−7.0%Reduced
Propel Bio Management, LLC750,000$7.08M4.12%00.0%Unchanged
Rock Springs Capital Management LP727,673$6.87M0.17%00.0%Unchanged
Qube Research & Technologies Ltd723,163$6.83M0.01%+480,255+197.7%Added
Vestal Point Capital, LP695,000$6.56M0.54%−330,000−32.2%Reduced
Simplify Asset Management Inc.676,031$6.38M0.61%+112,706+20.0%Added
D. E. Shaw & Co., Inc.625,176$5.90M0.01%+127,497+25.6%Added
Geode Capital Management, LLC563,458$5.32M0.00%+10,228+1.8%Added
Susquehanna International Group, LLP560,992$5.30M0.01%−105,601−15.8%Reduced
Affinity Asset Advisors, LLC550,339$5.20M0.84%+425,339+340.3%Added
Jane Street Group, LLC535,062$5.05M0.01%+188,212+54.3%Added
Invesco Ltd.496,679$4.69M0.00%+20,473+4.3%Added
Two Sigma Advisers, LP420,200$3.97M0.01%−76,000−15.3%Reduced
StemPoint Capital LP407,108$3.84M1.03%+30,535+8.1%Added
Silverarc Capital Management, LLC398,436$3.76M1.05%+398,436New
ADAR1 Capital Management, LLC339,825$3.21M0.88%−297,580−46.7%Reduced
Caption Management, LLC315,460$2.98M0.33%+315,460New
Bessemer Group Inc286,988$2.71M0.00%00.0%Unchanged
Standard Life Aberdeen plc256,888$2.43M0.00%00.0%Unchanged
State Street Corp256,861$2.42M0.00%+73,714+40.2%Added
Marshall Wace, LLP225,573$2.13M0.00%−279,529−55.3%Reduced
Point72 Asset Management, L.P.223,400$2.11M0.01%+223,400New
Mass General Brigham, Inc205,356$1.94M3.39%+205,356New
Alyeska Investment Group, L.P.202,148$1.91M0.01%00.0%Unchanged
Alliancebernstein L.P.186,965$1.76M0.00%−52,493−21.9%Reduced
Citigroup Inc178,564$1.69M0.00%−106,734−37.4%Reduced
Two Sigma Investments, LP175,224$1.65M0.00%−86,528−33.1%Reduced
Wellington Management Group LLP172,660$1.63M0.00%+172,660New
Cubist Systematic Strategies, LLC171,507$1.62M0.02%+171,507New
Susquehanna Portfolio Strategies, LLC168,775$1.59M0.04%00.0%Unchanged
JPMorgan Chase & Co158,935$1.50M0.00%+147,495+1,289.3%Added
CIBC World Markets Corp150,000$1.42M0.01%+150,000New
HSBC Holdings PLC149,627$1.41M0.00%+149,627New
Laurion Capital Management LP144,721$1.37M0.04%00.0%Unchanged
RBF Capital, LLC140,000$1.32M0.07%00.0%Unchanged
Fiduciary Trust Co136,555$1.29M0.02%00.0%Unchanged
Northern Trust Corp136,433$1.29M0.00%−8,532−5.9%Reduced
Opaleye Management Inc.130,000$1.23M0.27%00.0%Unchanged
HRT Financial LP123,408$1.16M0.01%+123,408New
Man Group plc102,226$965.0K0.00%+7,609+8.0%Added
Landscape Capital Management, L.L.C.94,775$894.7K0.08%+30,021+46.4%Added
American Century Companies Inc92,204$870.4K0.00%+27,581+42.7%Added
Point72 Asia (Singapore) Pte. Ltd.89,547$845.3K0.22%+89,547New
Bridgeway Capital Management, LLC88,564$836.0K0.02%−37,936−30.0%Reduced
Brevan Howard Capital Management LP88,483$835.3K0.08%+88,483New
Stifel Financial Corp85,014$802.5K0.00%+13,559+19.0%Added
Commonwealth Equity Services, LLC83,428$788.0K0.00%−13,000−13.5%Reduced
UBS Group AG72,768$686.9K0.00%+42,585+141.1%Added
Barclays PLC71,515$675.1K0.00%+3,330+4.9%Added
Gilder Gagnon Howe & Co LLC65,600$619.3K0.01%+65,600New
Bank of America Corp61,653$582.0K0.00%−125,819−67.1%Reduced
DekaBank Deutsche Girozentrale60,000$568.0K0.00%00.0%Unchanged
Squarepoint Ops LLC54,560$515.0K0.00%+54,560New
Y-Intercept (Hong Kong) Ltd54,416$513.7K0.04%+37,998+231.4%Added
PDT Partners, LLC49,518$467.4K0.04%+49,518New
Trexquant Investment LP47,222$445.8K0.01%+47,222New
Marathon Trading Investment Management LLC45,000$424.8K0.17%+45,000New
Alps Advisors Inc43,682$412.4K0.00%+3,828+9.6%Added
Centiva Capital, LP43,080$406.7K0.02%+43,080New
Acuitas Investments, LLC33,224$313.6K0.16%−101,626−75.4%Reduced
Jump Financial, LLC30,844$291.2K0.01%+30,844New
Simplex Trading, LLC30,739$290.0K0.01%+30,739New
Country Trust Bank30,186$285.0K0.01%00.0%Unchanged
Schonfeld Strategic Advisors LLC29,169$275.4K0.00%−403,364−93.3%Reduced
Denali Advisors LLC27,100$255.8K0.08%−30,700−53.1%Reduced
Brandywine Managers, LLC26,127$246.6K0.24%00.0%Unchanged
Brown Wealth Management, LLC25,000$236.0K0.10%00.0%Unchanged
Franklin Resources Inc24,821$234.3K0.00%00.0%Unchanged
Charles Schwab Investment Management Inc24,485$231.1K0.00%00.0%Unchanged
Wolverine Trading, LLC23,579$222.6K0.00%+9,832+71.5%Added
ExodusPoint Capital Management, LP21,419$202.0K0.00%−30,245−58.5%Reduced
Group One Trading, L.P.20,853$196.9K0.01%+494+2.4%Added
Jacobs Levy Equity Management, Inc20,472$193.3K0.00%−101,658−83.2%Reduced
Blackstone Group Inc.19,216$181.4K0.00%00.0%Unchanged
Polymer Capital Management (HK) LTD18,874$178.2K0.04%+18,874New
LMR Partners LLP17,539$165.6K0.00%+17,539New
Principal Financial Group Inc16,233$153.2K0.00%−1,760−9.8%Reduced
Price T Rowe Associates Inc15,900$151.0K0.00%00.0%Unchanged
Balyasny Asset Management LLC15,709$148.3K0.00%−89,470−85.1%Reduced
Gsa Capital Partners LLP15,162$143.0K0.01%+15,162New
CTC Alternative Strategies, Ltd.14,700$138.8K0.09%+14,700New
Alphabet Inc.14,262$134.6K0.01%00.0%Unchanged
Algert Global LLC13,670$129.0K0.01%−12,160−47.1%Reduced
XTX Topco Ltd13,154$124.2K0.02%+13,154New