Fulcrum Therapeutics, Inc.
FULC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001680581
In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Fulcrum Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 169
- −1 vs. Q4 2025
- Shares held
- 71.7M
- +7.83M (+12.3%) vs. Q4 2025
- Total value
- $550.1M
- −$172.3M (−23.9%) vs. Q4 2025
- New holders
- 37
- 74 more added
- Sold out
- 38
- 38 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 154 | $291.3M |
| Q1 2026 | 169 | $550.1M |
| Q4 2025 | 172 | $762.7M |
| Q3 2025 | 129 | $494.9M |
| Q2 2025 | 122 | $374.5M |
| Q1 2025 | 117 | $147.8M |
| Q4 2024 | 119 | $243.4M |
| Q3 2024 | 130 | $196.4M |
| Q2 2024 | 121 | $402.0M |
| Q1 2024 | 126 | $569.7M |
| Q4 2023 | 101 | $412.3M |
| Q3 2023 | 81 | $250.4M |
| Q2 2023 | 88 | $183.2M |
| Q1 2023 | 116 | $172.2M |
| Q4 2022 | 110 | $368.5M |
| Q3 2022 | 105 | $422.1M |
| Q2 2022 | 102 | $196.6M |
| Q1 2022 | 108 | $929.9M |
| Q4 2021 | 110 | $657.3M |
| Q3 2021 | 101 | $1.03B |
| Q2 2021 | 67 | $280.8M |
| Q1 2021 | 68 | $317.0M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Suvretta Capital Management, LLC | 6,561,111 | $50.3M | 1.36% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 6,053,960 | $46.4M | 0.49% | 00.0% | Unchanged |
| BlackRock, Inc. | 5,390,593 | $41.3M | 0.00% | +1,126,832+26.4% | Added |
| TCG Crossover Management, LLC | 5,250,000 | $40.3M | 1.15% | 00.0% | Unchanged |
| Braidwell LP | 3,134,922 | $24.0M | 0.80% | +73,700+2.4% | Added |
| Nantahala Capital Management, LLC | 3,050,040 | $23.4M | 1.46% | −1,243,306−29.0% | Reduced |
| Vanguard Capital Management LLC | 2,692,948 | $20.7M | 0.00% | +2,692,948 | New |
| Siren, L.L.C. | 2,350,000 | $18.0M | 0.50% | +400,000+20.5% | Added |
| First Turn Management, LLC | 2,256,109 | $17.3M | 1.93% | +363,426+19.2% | Added |
| Standard Life Aberdeen plc | 2,211,953 | $17.0M | 0.03% | +957,926+76.4% | Added |
| Point72 Asset Management, L.P. | 2,074,855 | $15.9M | 0.03% | −323,377−13.5% | Reduced |
| GSK plc | 1,785,714 | $13.7M | 2.29% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 1,779,946 | $13.7M | 0.03% | +809,507+83.4% | Added |
| Jones Hill Capital LP | 1,771,926 | $13.6M | 2.91% | +1,771,926 | New |
| D. E. Shaw & Co., Inc. | 1,623,281 | $12.5M | 0.01% | −290,474−15.2% | Reduced |
| State Street Corp | 1,549,851 | $11.9M | 0.00% | +544,506+54.2% | Added |
| Geode Capital Management, LLC | 1,486,542 | $11.4M | 0.00% | +380,729+34.4% | Added |
| Alyeska Investment Group, L.P. | 1,328,449 | $10.2M | 0.03% | +1,328,449 | New |
| Citadel Advisors LLC | 1,292,486 | $9.91M | 0.01% | +85,482+7.1% | Added |
| Assenagon Asset Management S.A. | 1,193,873 | $9.16M | 0.01% | +1,193,873 | New |
| Dimensional Fund Advisors LP | 1,130,281 | $8.66M | 0.00% | +79,157+7.5% | Added |
| Vestal Point Capital, LP | 1,100,000 | $8.44M | 0.24% | +150,000+15.8% | Added |
| Ikarian Capital, LLC | 1,049,161 | $8.05M | 1.15% | −326,311−23.7% | Reduced |
| Qube Research & Technologies Ltd | 974,739 | $7.48M | 0.01% | +582,250+148.3% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 736,684 | $5.65M | 0.01% | +154,307+26.5% | Added |
| Acadian Asset Management LLC | 727,315 | $5.57M | 0.01% | −9,425−1.3% | Reduced |
| Vanguard Portfolio Management LLC | 599,379 | $4.60M | 0.00% | +599,379 | New |
| Goldman Sachs Group Inc | 571,909 | $4.39M | 0.00% | +248,030+76.6% | Added |
| AQR Capital Management LLC | 543,165 | $4.17M | 0.00% | +527,663+3,403.8% | Added |
| Northern Trust Corp | 472,985 | $3.63M | 0.00% | −79,235−14.3% | Reduced |
| Trexquant Investment LP | 453,529 | $3.48M | 0.03% | +97,982+27.6% | Added |
| Charles Schwab Investment Management Inc | 426,869 | $3.27M | 0.00% | +37,973+9.8% | Added |
| Silverarc Capital Management, LLC | 419,949 | $3.22M | 0.38% | +25,299+6.4% | Added |
| Adage Capital Partners GP, L.L.C. | 400,000 | $3.07M | 0.00% | −1,300,000−76.5% | Reduced |
| Jump Financial, LLC | 369,805 | $2.84M | 0.04% | +277,605+301.1% | Added |
| Millennium Management LLC | 356,471 | $2.73M | 0.00% | +302,040+554.9% | Added |
| Vanguard Fiduciary Trust Co | 329,884 | $2.53M | 0.00% | +329,884 | New |
| UBS Group AG | 315,185 | $2.42M | 0.00% | +212,218+206.1% | Added |
| Jane Street Group, LLC | 310,417 | $2.38M | 0.00% | −183,333−37.1% | Reduced |
| Boothbay Fund Management, LLC | 303,988 | $2.33M | 0.05% | −213,538−41.3% | Reduced |
| Bessemer Group Inc | 286,988 | $2.20M | 0.00% | 00.0% | Unchanged |
| Panagora Asset Management Inc | 243,565 | $1.87M | 0.01% | +243,565 | New |
| DAFNA Capital Management LLC | 205,000 | $1.57M | 0.36% | +205,000 | New |
| Squarepoint Ops LLC | 175,944 | $1.35M | 0.00% | +110,092+167.2% | Added |
| Morgan Stanley | 173,337 | $1.33M | 0.00% | +7,714+4.7% | Added |
| American Century Companies Inc | 156,242 | $1.20M | 0.00% | −1,430−0.9% | Reduced |
| State of Wisconsin Investment Board | 154,435 | $1.18M | 0.00% | +67,936+78.5% | Added |
| Y-Intercept (Hong Kong) Ltd | 153,344 | $1.18M | 0.02% | +86,628+129.8% | Added |
| Bank of New York Mellon Corp | 149,942 | $1.15M | 0.00% | +33,036+28.3% | Added |
| Two Sigma Investments, LP | 139,000 | $1.07M | 0.00% | +139,000 | New |
| Gsa Capital Partners LLP | 136,664 | $1.05M | 0.07% | +36,955+37.1% | Added |
| Fiduciary Trust Co | 136,555 | $1.05M | 0.01% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 130,560 | $1.00M | 0.06% | −1,123,189−89.6% | Reduced |
| Nuveen, LLC | 129,618 | $994.2K | 0.00% | +17,415+15.5% | Added |
| Bank of America Corp | 126,559 | $970.7K | 0.00% | −104,618−45.3% | Reduced |
| Engineers Gate Manager LP | 126,109 | $967.3K | 0.01% | +126,109 | New |
| Wellington Management Group LLP | 118,600 | $909.7K | 0.00% | −27,827−19.0% | Reduced |
| Simplify Asset Management Inc. | 115,994 | $889.7K | 0.01% | −43,680−27.4% | Reduced |
| Invesco Ltd. | 111,125 | $852.3K | 0.00% | −306,064−73.4% | Reduced |
| Susquehanna International Group, LLP | 101,336 | $777.2K | 0.00% | +13,406+15.2% | Added |
| Barclays PLC | 88,458 | $678.5K | 0.00% | −44,083−33.3% | Reduced |
| Price T Rowe Associates Inc | 80,169 | $615.0K | 0.00% | +16,409+25.7% | Added |
| Russell Investments Group, Ltd. | 79,157 | $607.1K | 0.00% | +75,583+2,114.8% | Added |
| XTX Topco Ltd | 71,603 | $549.2K | 0.01% | +19,801+38.2% | Added |
| RBF Capital, LLC | 70,000 | $536.9K | 0.03% | −10,506−13.0% | Reduced |
| Atom Investors LP | 69,155 | $530.4K | 0.04% | +8,560+14.1% | Added |
| Rhumbline Advisers | 66,175 | $507.6K | 0.00% | +10,462+18.8% | Added |
| Creative Planning | 64,089 | $491.6K | 0.00% | +41,985+189.9% | Added |
| FMR LLC | 61,041 | $468.2K | 0.00% | +53,350+693.7% | Added |
| HSBC Holdings PLC | 58,636 | $441.5K | 0.00% | +15,374+35.5% | Added |
| Franklin Resources Inc | 54,666 | $419.3K | 0.00% | +10,417+23.5% | Added |
| Group One Trading, L.P. | 53,756 | $412.3K | 0.01% | +19,006+54.7% | Added |
| Alliancebernstein L.P. | 34,570 | $391.0K | 0.00% | +19,300+126.4% | Added |
| Burkehill Global Management, LP | 50,000 | $383.5K | 0.02% | 00.0% | Unchanged |
| STRS Ohio | 49,300 | $378.1K | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 48,828 | $374.5K | 0.00% | −238,268−83.0% | Reduced |
| Man Group plc | 46,119 | $353.7K | 0.00% | +30,866+202.4% | Added |
| EntryPoint Capital, LLC | 45,248 | $347.1K | 0.10% | +30,172+200.1% | Added |
| Graham Capital Management, L.P. | 42,741 | $327.8K | 0.01% | −5,723−11.8% | Reduced |
| Marex Group plc | 42,000 | $322.1K | 0.00% | +42,000 | New |
| Simplex Trading, LLC | 41,940 | $321.7K | 0.01% | +33,926+423.3% | Added |
| Commonwealth Equity Services, LLC | 40,290 | $309.0K | 0.00% | +290+0.7% | Added |
| BIT Capital GmbH | 40,000 | $306.8K | 0.02% | +40,000 | New |
| Matisse Capital | 39,649 | $304.1K | 0.13% | +26,189+194.6% | Added |
| Brevan Howard Capital Management LP | 39,444 | $302.5K | 0.00% | −9,456−19.3% | Reduced |
| Vanguard Global Advisers, LLC | 38,519 | $295.4K | 0.00% | +38,519 | New |
| Seven Fleet Capital Management LP | 38,100 | $292.2K | 0.09% | +38,100 | New |
| MetLife Investment Management | 33,164 | $254.4K | 0.00% | +10,450+46.0% | Added |
| Algert Global LLC | 33,050 | $253.5K | 0.00% | +33,050 | New |
| Woodline Partners LP | 30,793 | $236.2K | 0.00% | 00.0% | Unchanged |
| Country Trust Bank | 30,041 | $230.4K | 0.00% | 00.0% | Unchanged |
| LMR Partners LLP | 30,000 | $230.1K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 28,080 | $215.4K | 0.00% | +8,058+40.2% | Added |
| Pale Fire Capital SE | 26,100 | $200.2K | 0.02% | +26,100 | New |
| Quantinno Capital Management LP | 25,669 | $196.9K | 0.00% | −3,595−12.3% | Reduced |
| JPMorgan Chase & Co | 29,792 | $196.0K | 0.00% | +9,003+43.3% | Added |
| Citigroup Inc | 23,435 | $179.7K | 0.00% | −43,667−65.1% | Reduced |
| Mariner, LLC | 23,260 | $178.4K | 0.00% | +23,260 | New |
| ExodusPoint Capital Management, LP | 23,172 | $177.7K | 0.00% | +23,172 | New |
| Wells Fargo & Company | 22,551 | $173.0K | 0.00% | −143,844−86.4% | Reduced |