Fulcrum Therapeutics, Inc.
FULC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001680581
In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Fulcrum Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 119
- −9 vs. Q3 2024
- Shares held
- 51.7M
- −2.97M (−5.4%) vs. Q3 2024
- Total value
- $243.4M
- +$47.8M (+24.4%) vs. Q3 2024
- New holders
- 24
- 33 more added
- Sold out
- 33
- 40 more reduced
2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 154 | $291.3M |
| Q1 2026 | 169 | $550.1M |
| Q4 2025 | 172 | $762.7M |
| Q3 2025 | 129 | $494.9M |
| Q2 2025 | 122 | $374.5M |
| Q1 2025 | 117 | $147.8M |
| Q4 2024 | 119 | $243.4M |
| Q3 2024 | 130 | $196.4M |
| Q2 2024 | 121 | $402.0M |
| Q1 2024 | 126 | $569.7M |
| Q4 2023 | 101 | $412.3M |
| Q3 2023 | 81 | $250.4M |
| Q2 2023 | 88 | $183.2M |
| Q1 2023 | 116 | $172.2M |
| Q4 2022 | 110 | $368.5M |
| Q3 2022 | 105 | $422.1M |
| Q2 2022 | 102 | $196.6M |
| Q1 2022 | 108 | $929.9M |
| Q4 2021 | 110 | $657.3M |
| Q3 2021 | 101 | $1.03B |
| Q2 2021 | 67 | $280.8M |
| Q1 2021 | 68 | $317.0M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 10,229,099 | $48.1M | 0.64% | 00.0% | Unchanged |
| TCG Crossover Management, LLC | 5,250,000 | $24.7M | 2.41% | 00.0% | Unchanged |
| BlackRock, Inc. | 5,169,429 | $24.3M | 0.00% | −537,098−9.4% | Reduced |
| Nantahala Capital Management, LLC | 4,779,708 | $22.5M | 1.57% | +1,7960.0% | Added |
| Suvretta Capital Management, LLC | 3,338,466 | $15.7M | 0.58% | +2,155,675+182.3% | Added |
| Vanguard Group Inc | 3,249,607 | $15.3M | 0.00% | −24,985−0.8% | Reduced |
| Adage Capital Partners GP, L.L.C. | 3,000,000 | $14.1M | 0.02% | +1,000,000+50.0% | Added |
| Morgan Stanley | 1,531,732 | $7.20M | 0.00% | +1,181,047+336.8% | Added |
| Dimensional Fund Advisors LP | 1,418,690 | $6.67M | 0.00% | −4,805−0.3% | Reduced |
| Woodline Partners LP | 1,410,520 | $6.63M | 0.04% | +739,713+110.3% | Added |
| Geode Capital Management, LLC | 1,294,515 | $6.09M | 0.00% | −26,347−2.0% | Reduced |
| State Street Corp | 1,245,319 | $5.85M | 0.00% | −434,910−25.9% | Reduced |
| Northern Trust Corp | 710,321 | $3.34M | 0.00% | +142,578+25.1% | Added |
| D. E. Shaw & Co., Inc. | 583,203 | $2.74M | 0.00% | −174,528−23.0% | Reduced |
| Goldman Sachs Group Inc | 542,258 | $2.55M | 0.00% | −385,703−41.6% | Reduced |
| Charles Schwab Investment Management Inc | 526,045 | $2.47M | 0.00% | −43,140−7.6% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 367,594 | $1.73M | 0.01% | +234,810+176.8% | Added |
| Two Sigma Advisers, LP | 343,600 | $1.61M | 0.00% | −38,600−10.1% | Reduced |
| Citadel Advisors LLC | 333,323 | $1.57M | 0.00% | −1,015,470−75.3% | Reduced |
| Shay Capital LLC | 301,464 | $1.42M | 0.35% | +12,227+4.2% | Added |
| Bessemer Group Inc | 286,988 | $1.35M | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 285,491 | $1.34M | 0.00% | −424−0.1% | Reduced |
| Exome Asset Management LLC | 283,599 | $1.33M | 1.00% | +283,599 | New |
| Perceptive Advisors LLC | 238,000 | $1.12M | 0.03% | +238,000 | New |
| Susquehanna Fundamental Investments, LLC | 213,213 | $1.00M | 0.02% | +213,213 | New |
| Ikarian Capital, LLC | 200,096 | $940.5K | 0.27% | +125,096+166.8% | Added |
| ADAR1 Capital Management, LLC | 196,248 | $922.4K | 0.19% | +140,446+251.7% | Added |
| Wellington Management Group LLP | 172,158 | $809.1K | 0.00% | −4,003−2.3% | Reduced |
| Nuveen Asset Management, LLC | 169,549 | $796.9K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 169,542 | $796.8K | 0.00% | −102,565−37.7% | Reduced |
| Graham Capital Management, L.P. | 144,942 | $681.2K | 0.02% | +53,726+58.9% | Added |
| Bank of New York Mellon Corp | 141,873 | $666.8K | 0.00% | +3,126+2.3% | Added |
| Bridgeway Capital Management, LLC | 140,000 | $658.0K | 0.01% | +140,000 | New |
| Fiduciary Trust Co | 136,555 | $641.8K | 0.01% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 130,693 | $614.3K | 0.00% | +130,693 | New |
| Matisse Capital | 128,445 | $603.7K | 0.31% | +21,728+20.4% | Added |
| Barclays PLC | 122,070 | $573.7K | 0.00% | −2,071−1.7% | Reduced |
| American Century Companies Inc | 120,611 | $566.9K | 0.00% | +6,770+5.9% | Added |
| Mackenzie Financial Corp | 118,025 | $554.7K | 0.00% | +94,997+412.5% | Added |
| DekaBank Deutsche Girozentrale | 60,000 | $538.0K | 0.00% | 00.0% | Unchanged |
| LMR Partners LLP | 112,500 | $528.8K | 0.01% | +112,500 | New |
| Altium Capital Management LP | 111,812 | $525.5K | 0.16% | +111,812 | New |
| Bank of America Corp | 91,866 | $431.8K | 0.00% | −8,049−8.1% | Reduced |
| STRS Ohio | 91,200 | $428.6K | 0.00% | 00.0% | Unchanged |
| FMR LLC | 90,465 | $425.2K | 0.00% | −1,633,550−94.8% | Reduced |
| Rhumbline Advisers | 88,607 | $416.4K | 0.00% | +1,399+1.6% | Added |
| Prelude Capital Management, LLC | 86,085 | $404.6K | 0.03% | +62,985+272.7% | Added |
| Commonwealth Equity Services, LLC | 83,428 | $392.0K | 0.00% | −1,000−1.2% | Reduced |
| Simplify Asset Management Inc. | 80,714 | $379.4K | 0.03% | −270,600−77.0% | Reduced |
| RBF Capital, LLC | 80,506 | $378.4K | 0.02% | −25,622−24.1% | Reduced |
| JPMorgan Chase & Co | 79,120 | $371.9K | 0.00% | −108,043−57.7% | Reduced |
| UBS Group AG | 77,392 | $363.7K | 0.00% | −3,241−4.0% | Reduced |
| Millennium Management LLC | 76,123 | $357.8K | 0.00% | +52,628+224.0% | Added |
| HSBC Holdings PLC | 75,959 | $354.7K | 0.00% | +26,944+55.0% | Added |
| Nebula Research & Development LLC | 75,140 | $353.2K | 0.04% | −6,595−8.1% | Reduced |
| HRT Financial LP | 68,069 | $319.0K | 0.00% | +68,069 | New |
| Verition Fund Management LLC | 67,043 | $315.1K | 0.00% | +29,400+78.1% | Added |
| Alliancebernstein L.P. | 65,590 | $308.3K | 0.00% | 00.0% | Unchanged |
| MYDA Advisors LLC | 63,970 | $300.7K | 0.09% | +63,970 | New |
| Boothbay Fund Management, LLC | 59,533 | $279.8K | 0.01% | +37,596+171.4% | Added |
| Price T Rowe Associates Inc | 52,368 | $247.0K | 0.00% | +16,656+46.6% | Added |
| Citigroup Inc | 49,722 | $233.7K | 0.00% | −24,981−33.4% | Reduced |
| AQR Capital Management LLC | 45,641 | $214.5K | 0.00% | −52,835−53.7% | Reduced |
| Jane Street Group, LLC | 45,159 | $212.2K | 0.00% | −74,734−62.3% | Reduced |
| Sherbrooke Park Advisers LLC | 45,157 | $212.2K | 0.07% | −182,068−80.1% | Reduced |
| Susquehanna International Group, LLP | 40,777 | $191.7K | 0.00% | +4,206+11.5% | Added |
| MetLife Investment Management | 40,107 | $188.5K | 0.00% | +23,792+145.8% | Added |
| Bailard, Inc. | 35,900 | $168.7K | 0.00% | +35,900 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 35,601 | $167.3K | 0.00% | +1,520+4.5% | Added |
| Acadian Asset Management LLC | 35,707 | $167.0K | 0.00% | −153,254−81.1% | Reduced |
| Wells Fargo & Company | 34,264 | $161.0K | 0.00% | +8,761+34.4% | Added |
| Algert Global LLC | 34,117 | $160.3K | 0.00% | −5,570−14.0% | Reduced |
| Corebridge Financial, Inc. | 30,850 | $145.0K | 0.00% | −2,329−7.0% | Reduced |
| Intech Investment Management LLC | 30,499 | $143.3K | 0.00% | +13,057+74.9% | Added |
| SG Americas Securities, LLC | 30,442 | $143.0K | 0.00% | −2,577−7.8% | Reduced |
| Country Trust Bank | 30,186 | $141.9K | 0.00% | 00.0% | Unchanged |
| Invesco Ltd. | 29,976 | $140.9K | 0.00% | −686−2.2% | Reduced |
| Group One Trading, L.P. | 29,489 | $138.6K | 0.00% | −39,711−57.4% | Reduced |
| Franklin Resources Inc | 24,821 | $116.7K | 0.00% | 00.0% | Unchanged |
| Corton Capital Inc. | 23,498 | $110.4K | 0.06% | −34,101−59.2% | Reduced |
| Manufacturers Life Insurance Company, The | 23,470 | $110.3K | 0.00% | −304−1.3% | Reduced |
| Prudential Financial Inc | 22,675 | $106.6K | 0.00% | 00.0% | Unchanged |
| Zacks Investment Management | 20,999 | $98.7K | 0.00% | +20,999 | New |
| J. Goldman & Co LP | 20,250 | $95.2K | 0.00% | 00.0% | Unchanged |
| Cantor Fitzgerald, L. P. | 20,000 | $94.0K | 0.00% | +20,000 | New |
| Voya Investment Management LLC | 19,888 | $93.5K | 0.00% | −1,783−8.2% | Reduced |
| ProShare Advisors LLC | 17,475 | $82.1K | 0.00% | +2,065+13.4% | Added |
| Mariner, LLC | 16,516 | $77.6K | 0.00% | +16,516 | New |
| Jain Global LLC | 15,409 | $72.4K | 0.00% | +15,409 | New |
| Alphabet Inc. | 14,262 | $67.2K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 13,100 | $61.6K | 0.00% | 00.0% | Unchanged |
| Winton Group Ltd | 12,997 | $61.1K | 0.00% | −31,204−70.6% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 12,475 | $58.6K | 0.00% | +12,475 | New |
| Simplex Trading, LLC | 10,455 | $49.0K | 0.00% | −39,309−79.0% | Reduced |
| BNP Paribas Arbitrage, SA | 8,014 | $37.7K | 0.00% | +8,014 | New |
| Legal & General Group Plc | 6,520 | $30.6K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 6,079 | $28.6K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 5,827 | $28.0K | 0.00% | −415−6.6% | Reduced |
| PrairieView Partners, LLC | 5,000 | $23.0K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 4,496 | $21.1K | 0.00% | 00.0% | Unchanged |