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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Fulcrum Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
119
−9 vs. Q3 2024
Shares held
51.7M
−2.97M (−5.4%) vs. Q3 2024
Total value
$243.4M
+$47.8M (+24.4%) vs. Q3 2024
New holders
24
33 more added
Sold out
33
40 more reduced

2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 119 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ4 2024: $243.4M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q3 2024.

Institutions holding FULC in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
CWM, LLC10$00.00%+5+100.0%Added
Zurcher Kantonalbank (Zurich Cantonalbank)3$140.00%−2,472−99.9%Reduced
The PNC Financial Services Group, Inc.5$240.00%+5New
Larson Financial Group LLC15$710.00%+15New
SBI Securities Co., Ltd.26$1220.00%+26New
Advisor Group Holdings, Inc.95$4470.00%00.0%Unchanged
HighMark Wealth Management LLC100$4700.00%+100New
C M Bidwell & Associates Ltd117$5500.00%+117New
Caitong International Asset Management Co., Ltd145$6820.00%+145New
Russell Investments Group, Ltd.314$1.48K0.00%+267+568.1%Added
National Bank of Canada460$2.16K0.00%00.0%Unchanged
Belvedere Trading LLC758$3.56K0.00%+758New
Steward Partners Investment Advisory, LLC790$3.71K0.00%00.0%Unchanged
Sterling Capital Management LLC1,239$5.82K0.00%+1,099+785.0%Added
Nisa Investment Advisors, LLC1,667$7.83K0.00%+328+24.5%Added
Amalgamated Bank2,147$10.0K0.00%00.0%Unchanged
IFP Advisors, Inc2,294$11.0K0.00%+1,393+154.6%Added
Skopos Labs, Inc.3,936$18.5K0.01%+3,936New
Tower Research Capital LLC (TRC)3,975$18.7K0.00%−24,145−85.9%Reduced
California State Teachers Retirement System4,496$21.1K0.00%00.0%Unchanged
PrairieView Partners, LLC5,000$23.0K0.00%00.0%Unchanged
Royal Bank of Canada5,827$28.0K0.00%−415−6.6%Reduced
Ameritas Investment Partners, Inc.6,079$28.6K0.00%00.0%Unchanged
Legal & General Group Plc6,520$30.6K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA8,014$37.7K0.00%+8,014New
Simplex Trading, LLC10,455$49.0K0.00%−39,309−79.0%Reduced
Police & Firemen's Retirement System of New Jersey12,475$58.6K0.00%+12,475New
Winton Group Ltd12,997$61.1K0.00%−31,204−70.6%Reduced
New York State Common Retirement Fund13,100$61.6K0.00%00.0%Unchanged
Alphabet Inc.14,262$67.2K0.00%00.0%Unchanged
Jain Global LLC15,409$72.4K0.00%+15,409New
Mariner, LLC16,516$77.6K0.00%+16,516New
ProShare Advisors LLC17,475$82.1K0.00%+2,065+13.4%Added
Voya Investment Management LLC19,888$93.5K0.00%−1,783−8.2%Reduced
Cantor Fitzgerald, L. P.20,000$94.0K0.00%+20,000New
J. Goldman & Co LP20,250$95.2K0.00%00.0%Unchanged
Zacks Investment Management20,999$98.7K0.00%+20,999New
Prudential Financial Inc22,675$106.6K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The23,470$110.3K0.00%−304−1.3%Reduced
Corton Capital Inc.23,498$110.4K0.06%−34,101−59.2%Reduced
Franklin Resources Inc24,821$116.7K0.00%00.0%Unchanged
Group One Trading, L.P.29,489$138.6K0.00%−39,711−57.4%Reduced
Invesco Ltd.29,976$140.9K0.00%−686−2.2%Reduced
Country Trust Bank30,186$141.9K0.00%00.0%Unchanged
SG Americas Securities, LLC30,442$143.0K0.00%−2,577−7.8%Reduced
Intech Investment Management LLC30,499$143.3K0.00%+13,057+74.9%Added
Corebridge Financial, Inc.30,850$145.0K0.00%−2,329−7.0%Reduced
Algert Global LLC34,117$160.3K0.00%−5,570−14.0%Reduced
Wells Fargo & Company34,264$161.0K0.00%+8,761+34.4%Added
Acadian Asset Management LLC35,707$167.0K0.00%−153,254−81.1%Reduced
Mirae Asset Global ETFs Holdings Ltd.35,601$167.3K0.00%+1,520+4.5%Added
Bailard, Inc.35,900$168.7K0.00%+35,900New
MetLife Investment Management40,107$188.5K0.00%+23,792+145.8%Added
Susquehanna International Group, LLP40,777$191.7K0.00%+4,206+11.5%Added
Sherbrooke Park Advisers LLC45,157$212.2K0.07%−182,068−80.1%Reduced
Jane Street Group, LLC45,159$212.2K0.00%−74,734−62.3%Reduced
AQR Capital Management LLC45,641$214.5K0.00%−52,835−53.7%Reduced
Citigroup Inc49,722$233.7K0.00%−24,981−33.4%Reduced
Price T Rowe Associates Inc52,368$247.0K0.00%+16,656+46.6%Added
Boothbay Fund Management, LLC59,533$279.8K0.01%+37,596+171.4%Added
MYDA Advisors LLC63,970$300.7K0.09%+63,970New
Alliancebernstein L.P.65,590$308.3K0.00%00.0%Unchanged
Verition Fund Management LLC67,043$315.1K0.00%+29,400+78.1%Added
HRT Financial LP68,069$319.0K0.00%+68,069New
Nebula Research & Development LLC75,140$353.2K0.04%−6,595−8.1%Reduced
HSBC Holdings PLC75,959$354.7K0.00%+26,944+55.0%Added
Millennium Management LLC76,123$357.8K0.00%+52,628+224.0%Added
UBS Group AG77,392$363.7K0.00%−3,241−4.0%Reduced
JPMorgan Chase & Co79,120$371.9K0.00%−108,043−57.7%Reduced
RBF Capital, LLC80,506$378.4K0.02%−25,622−24.1%Reduced
Simplify Asset Management Inc.80,714$379.4K0.03%−270,600−77.0%Reduced
Commonwealth Equity Services, LLC83,428$392.0K0.00%−1,000−1.2%Reduced
Prelude Capital Management, LLC86,085$404.6K0.03%+62,985+272.7%Added
Rhumbline Advisers88,607$416.4K0.00%+1,399+1.6%Added
FMR LLC90,465$425.2K0.00%−1,633,550−94.8%Reduced
STRS Ohio91,200$428.6K0.00%00.0%Unchanged
Bank of America Corp91,866$431.8K0.00%−8,049−8.1%Reduced
Altium Capital Management LP111,812$525.5K0.16%+111,812New
LMR Partners LLP112,500$528.8K0.01%+112,500New
DekaBank Deutsche Girozentrale60,000$538.0K0.00%00.0%Unchanged
Mackenzie Financial Corp118,025$554.7K0.00%+94,997+412.5%Added
American Century Companies Inc120,611$566.9K0.00%+6,770+5.9%Added
Barclays PLC122,070$573.7K0.00%−2,071−1.7%Reduced
Matisse Capital128,445$603.7K0.31%+21,728+20.4%Added
State Board of Administration of Florida Retirement System130,693$614.3K0.00%+130,693New
Fiduciary Trust Co136,555$641.8K0.01%00.0%Unchanged
Bridgeway Capital Management, LLC140,000$658.0K0.01%+140,000New
Bank of New York Mellon Corp141,873$666.8K0.00%+3,126+2.3%Added
Graham Capital Management, L.P.144,942$681.2K0.02%+53,726+58.9%Added
Two Sigma Investments, LP169,542$796.8K0.00%−102,565−37.7%Reduced
Nuveen Asset Management, LLC169,549$796.9K0.00%00.0%Unchanged
Wellington Management Group LLP172,158$809.1K0.00%−4,003−2.3%Reduced
ADAR1 Capital Management, LLC196,248$922.4K0.19%+140,446+251.7%Added
Ikarian Capital, LLC200,096$940.5K0.27%+125,096+166.8%Added
Susquehanna Fundamental Investments, LLC213,213$1.00M0.02%+213,213New
Perceptive Advisors LLC238,000$1.12M0.03%+238,000New
Exome Asset Management LLC283,599$1.33M1.00%+283,599New
Deutsche Bank AG285,491$1.34M0.00%−424−0.1%Reduced
Bessemer Group Inc286,988$1.35M0.00%00.0%Unchanged
Shay Capital LLC301,464$1.42M0.35%+12,227+4.2%Added