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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q2 2021

Institutional positions in Fulcrum Therapeutics, Inc. as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
67
−1 vs. Q1 2021
Shares held
26.8M
−114.5K (−0.4%) vs. Q1 2021
Total value
$280.8M
−$36.2M (−11.4%) vs. Q1 2021
New holders
10
30 more added
Sold out
11
16 more reduced

Compare with Q1 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2021: 67 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ2 2021: $280.8M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q2 2021

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q1 2021.

Institutions holding FULC in Q2 2021
InstitutionSharesValue% of portfolioChange in sharesAction
TRV GP III, LLC5,962,202$62.5M10.91%00.0%Unchanged
RTW Investments, LP3,205,291$33.6M0.51%00.0%Unchanged
FMR LLC2,379,481$24.9M0.00%−36,250−1.5%Reduced
TRV GP IV, LLC2,343,154$24.6M11.69%00.0%Unchanged
Suvretta Capital Management, LLC1,627,444$17.1M0.26%+101,559+6.7%Added
Cowen and Company, LLC1,319,887$13.8M0.73%+438,055+49.7%Added
BlackRock Inc.1,297,445$13.6M0.00%+168,866+15.0%Added
Casdin Capital, LLC1,154,476$12.1M0.31%−86,700−7.0%Reduced
Vanguard Group Inc907,035$9.51M0.00%+63,840+7.6%Added
Alphabet Inc.678,141$7.11M0.14%00.0%Unchanged
Millennium Management LLC625,635$6.56M0.01%+30,574+5.1%Added
Acuta Capital Partners, LLC604,074$6.33M2.71%−18,426−3.0%Reduced
Point72 Asset Management, L.P.552,885$5.79M0.03%−22,361−3.9%Reduced
Harvard Management Co Inc410,714$4.30M0.25%00.0%Unchanged
Citadel Advisors LLC410,525$4.30M0.00%+410,525New
Geode Capital Management, LLC356,592$3.74M0.00%+71,855+25.2%Added
State Street Corp312,225$3.27M0.00%+57,728+22.7%Added
Perceptive Advisors LLC294,118$3.08M0.04%+294,118New
Bessemer Group Inc285,714$2.99M0.01%00.0%Unchanged
Northern Trust Corp217,711$2.28M0.00%+20,503+10.4%Added
Altium Capital Management LP213,533$2.24M0.52%+213,533New
JPMorgan Chase & Co184,572$1.93M0.00%−80,933−30.5%Reduced
Ikarian Capital, LLC162,700$1.71M0.30%−264,039−61.9%Reduced
Platinum Investment Management Ltd152,186$1.59M0.04%+68,636+82.1%Added
Parkman Healthcare Partners LLC146,389$1.53M0.34%+20,651+16.4%Added
Fiduciary Trust Co125,999$1.32M0.03%+1,000+0.8%Added
Nuveen Asset Management, LLC116,031$1.22M0.00%−27,171−19.0%Reduced
Sio Capital Management, LLC77,477$812.0K0.22%−113,795−59.5%Reduced
Dimensional Fund Advisors LP75,583$792.0K0.00%+25,768+51.7%Added
Morgan Stanley72,296$757.0K0.00%+4,491+6.6%Added
Bank of New York Mellon Corp63,972$670.0K0.00%+21,725+51.4%Added
Charles Schwab Investment Management Inc54,284$569.0K0.00%+10,654+24.4%Added
Country Trust Bank37,341$391.0K0.01%00.0%Unchanged
California State Teachers Retirement System30,559$320.0K0.00%+4,872+19.0%Added
Boothbay Fund Management, LLC29,050$304.0K0.01%−21,834−42.9%Reduced
Goldman Sachs Group Inc27,466$288.0K0.00%+13,099+91.2%Added
MYDA Advisors LLC25,000$262.0K0.07%+9,263+58.9%Added
Bank of Montreal24,101$241.0K0.00%+23,531+4,128.2%Added
Rhumbline Advisers22,475$236.0K0.00%+10,120+81.9%Added
Brandywine Managers, LLC20,388$214.0K0.24%00.0%Unchanged
PDT Partners, LLC18,000$189.0K0.01%−2,343−11.5%Reduced
Alliancebernstein L.P.16,600$174.0K0.00%+900+5.7%Added
Two Sigma Investments, LP15,611$164.0K0.00%+1,632+11.7%Added
Jacobs Levy Equity Management, Inc13,789$145.0K0.00%+13,789New
Deutsche Bank AG13,150$138.0K0.00%+3,203+32.2%Added
Jump Financial, LLC12,699$133.0K0.01%+12,699New
New York State Common Retirement Fund12,410$130.0K0.00%+143+1.2%Added
American International Group, Inc.12,411$130.0K0.00%+2,485+25.0%Added
Engineers Gate Manager LP11,773$123.0K0.01%−5,371−31.3%Reduced
ProShare Advisors LLC11,619$122.0K0.00%+11,619New
Bank of America Corp10,277$108.0K0.00%+5,272+105.3%Added
Bank Julius Baer & Co. Ltd, Zurich8,492$89.0K0.00%+8,492New
Wells Fargo & Company7,932$83.0K0.00%−1,417−15.2%Reduced
Citigroup Inc6,919$73.0K0.00%+5,178+297.4%Added
Nisa Investment Advisors, LLC5,050$53.0K0.00%+5,050New
STRS Ohio3,200$33.0K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC2,795$29.0K0.00%−860−23.5%Reduced
Legal & General Group Plc1,765$18.0K0.00%−143−7.5%Reduced
Tower Research Capital LLC (TRC)1,653$17.0K0.00%+633+62.1%Added
Royal Bank of Canada1,518$16.0K0.00%−168−10.0%Reduced
Ameritas Investment Partners, Inc.1,100$12.0K0.00%00.0%Unchanged
UBS Group AG942$10.0K0.00%−579−38.1%Reduced
Panagora Asset Management Inc828$9.00K0.00%+436+111.2%Added
Penserra Capital Management LLC745$7.00K0.00%+20+2.8%Added
Federated Hermes, Inc.658$7.00K0.00%+658New
Smith Asset Management Group LP520$5.00K0.00%+520New
Daiwa Securities Group Inc.52$1.00K0.00%00.0%Unchanged
Driehaus Capital Management LLC0$00.00%−876,211−100.0%Sold out
Burrage Capital Management LLC0$00.00%−319,819−100.0%Sold out
Pura Vida Investments, LLC0$00.00%−126,068−100.0%Sold out
Silverarc Capital Management, LLC0$00.00%−121,302−100.0%Sold out
Darwin Global Management, Ltd.0$00.00%−49,868−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−31,594−100.0%Sold out
California Public Employees Retirement System0$00.00%−30,000−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−19,900−100.0%Sold out
Manufacturers Life Insurance Company, The0$00.00%−11,460−100.0%Sold out
Acadian Asset Management LLC0$00.00%−3,471−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−90−100.0%Sold out