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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q2 2022

Institutional positions in Fulcrum Therapeutics, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
102
−5 vs. Q1 2022
Shares held
40.0M
+533.6K (+1.4%) vs. Q1 2022
Total value
$196.6M
−$733.2M (−78.9%) vs. Q1 2022
New holders
20
40 more added
Sold out
25
22 more reduced

1 institution that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 102 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ2 2022: $196.6M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q1 2022.

Institutions holding FULC in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC6,127,231$30.0M0.00%+30,753+0.5%Added
TRV GP III, LLC3,962,202$19.4M7.94%00.0%Unchanged
RTW Investments, LP3,961,194$19.4M0.50%+350,000+9.7%Added
Suvretta Capital Management, LLC3,355,624$16.4M0.63%+742,212+28.4%Added
BlackRock Inc.2,654,378$13.0M0.00%+425,768+19.1%Added
Cowen and Company, LLC2,385,885$11.7M1.15%−1,067,486−30.9%Reduced
TRV GP IV, LLC2,343,154$11.5M7.55%00.0%Unchanged
Point72 Asset Management, L.P.1,988,800$9.74M0.05%+1,663,800+511.9%Added
Logos Global Management LP1,950,000$9.55M1.75%+950,000+95.0%Added
Vanguard Group Inc1,529,662$7.50M0.00%+25,841+1.7%Added
Morgan Stanley1,178,956$5.78M0.00%+70,532+6.4%Added
Deep Track Capital, LP1,000,000$4.90M0.34%+350,000+53.8%Added
State Street Corp648,666$3.18M0.00%−27,288−4.0%Reduced
Geode Capital Management, LLC566,513$2.77M0.00%+36,376+6.9%Added
Harvard Management Co Inc410,714$2.01M0.23%00.0%Unchanged
Nuveen Asset Management, LLC401,142$1.97M0.00%+109,810+37.7%Added
Rock Springs Capital Management LP384,590$1.88M0.05%−50,000−11.5%Reduced
Dimensional Fund Advisors LP362,104$1.77M0.00%+79,311+28.0%Added
Northern Trust Corp308,294$1.51M0.00%+51,368+20.0%Added
Perceptive Advisors LLC294,118$1.44M0.05%00.0%Unchanged
Bessemer Group Inc285,714$1.40M0.00%00.0%Unchanged
Goldman Sachs Group Inc284,305$1.39M0.00%+46,663+19.6%Added
Adage Capital Partners GP, L.L.C.270,000$1.32M0.00%−1,680,000−86.2%Reduced
Parkman Healthcare Partners LLC262,689$1.29M0.47%+98,236+59.7%Added
Alphabet Inc.255,452$1.25M0.07%00.0%Unchanged
Cubist Systematic Strategies, LLC253,054$1.24M0.01%+242,167+2,224.4%Added
Two Sigma Investments, LP214,763$1.05M0.00%+197,863+1,170.8%Added
Acuta Capital Partners, LLC200,000$980.0K0.55%00.0%Unchanged
JPMorgan Chase & Co198,115$971.0K0.00%−2,271−1.1%Reduced
D. E. Shaw & Co., Inc.139,482$683.0K0.00%−407,922−74.5%Reduced
Fiduciary Trust Co132,472$649.0K0.01%00.0%Unchanged
Man Group plc–$612.0K0.00%–New
Two Sigma Advisers, LP111,300$545.0K0.00%+25,800+30.2%Added
Bank of New York Mellon Corp104,420$512.0K0.00%+3,781+3.8%Added
Bank of America Corp103,667$508.0K0.00%+88,836+599.0%Added
Charles Schwab Investment Management Inc85,919$422.0K0.00%+13,710+19.0%Added
Millennium Management LLC81,197$398.0K0.00%+81,197New
Renaissance Technologies LLC68,000$333.0K0.00%+68,000New
Swiss National Bank62,400$306.0K0.00%00.0%Unchanged
Tekla Capital Management LLC58,537$287.0K0.01%−18,756−24.3%Reduced
Citadel Advisors LLC56,047$275.0K0.00%−56,156−50.0%Reduced
Rhumbline Advisers47,527$233.0K0.00%+13,412+39.3%Added
Jane Street Group, LLC37,930$186.0K0.00%+22,972+153.6%Added
California State Teachers Retirement System36,701$180.0K0.00%+2,059+5.9%Added
Alliancebernstein L.P.33,500$164.0K0.00%+11,900+55.1%Added
Qube Research & Technologies Ltd31,813$156.0K0.00%+31,813New
Occudo Quantitative Strategies LP31,438$154.0K0.01%+31,438New
Squarepoint Ops LLC30,936$152.0K0.00%+567+1.9%Added
Schonfeld Strategic Advisors LLC30,600$150.0K0.00%−9,000−22.7%Reduced
Country Trust Bank30,186$148.0K0.00%−5,000−14.2%Reduced
Victory Capital Management Inc30,012$147.0K0.00%+1,105+3.8%Added
Price T Rowe Associates Inc29,717$146.0K0.00%+4,512+17.9%Added
Jump Financial, LLC29,000$142.0K0.01%+29,000New
Panagora Asset Management Inc28,646$140.0K0.00%00.0%Unchanged
State of Wisconsin Investment Board28,284$139.0K0.00%−6,616−19.0%Reduced
XTX Topco Ltd27,799$136.0K0.06%+27,799New
Brandywine Managers, LLC26,127$128.0K0.31%00.0%Unchanged
Cornercap Investment Counsel Inc25,941$127.0K0.02%+25,941New
Stifel Financial Corp24,600$121.0K0.00%+24,600New
Gsa Capital Partners LLP22,822$112.0K0.02%+22,822New
Deutsche Bank AG21,450$105.0K0.00%−3,849−15.2%Reduced
Engineers Gate Manager LP21,356$105.0K0.00%+21,356New
Credit Suisse AG21,261$104.0K0.00%+3,105+17.1%Added
Ameriprise Financial Inc20,664$101.0K0.00%+20,664New
New York State Common Retirement Fund18,555$91.0K0.00%−46−0.2%Reduced
Susquehanna International Group, LLP17,687$87.0K0.00%+17,687New
Legal & General Group Plc17,319$85.0K0.00%+991+6.1%Added
Ensign Peak Advisors, Inc17,200$84.0K0.00%00.0%Unchanged
Healthcare of Ontario Pension Plan Trust Fund17,000$83.0K0.00%+17,000New
American International Group, Inc.15,983$78.0K0.00%+2,338+17.1%Added
Balyasny Asset Management LLC15,684$77.0K0.00%+15,684New
Manufacturers Life Insurance Company, The14,970$73.4K0.00%+3,398+29.4%Added
UBS Asset Management Americas Inc14,800$72.5K0.00%00.0%Unchanged
Simplex Trading, LLC14,005$68.0K0.00%−2,622−15.8%Reduced
AQR Capital Management LLC13,966$68.0K0.00%+13,966New
Voya Investment Management LLC13,413$66.0K0.00%+2,035+17.9%Added
SG Americas Securities, LLC13,173$65.0K0.00%+8,884+207.1%Added
Delphia (USA) Inc.11,784$58.0K0.04%+11,784New
Invesco Ltd.11,100$55.0K0.00%−212,360−95.0%Reduced
Corton Capital Inc.10,759$53.0K0.05%+847+8.5%Added
Bank Julius Baer & Co. Ltd, Zurich8,500$42.0K0.00%00.0%Unchanged
STRS Ohio6,800$33.0K0.00%00.0%Unchanged
Wells Fargo & Company5,870$29.0K0.00%−8,183−58.2%Reduced
Tower Research Capital LLC (TRC)5,903$28.0K0.00%+5,239+789.0%Added
Point72 Hong Kong Ltd4,495$22.0K0.00%+4,495New
Cutler Group LP4,338$21.0K0.00%+3,438+382.0%Added
Amalgamated Bank4,028$20.0K0.00%+704+21.2%Added
Denali Advisors LLC3,900$19.0K0.01%00.0%Unchanged
Citigroup Inc3,740$18.0K0.00%−25,488−87.2%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)2,655$13.0K0.00%00.0%Unchanged
PrairieView Partners, LLC2,200$11.0K0.00%+1,700+340.0%Added
Ameritas Investment Partners, Inc.2,042$10.0K0.00%00.0%Unchanged
Barclays PLC1,713$8.00K0.00%−21,667−92.7%Reduced
National Bank of Canada460$2.00K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC223$1.00K0.00%−16,977−98.7%Reduced
Royal Bank of Canada200$1.00K0.00%−1,496−88.2%Reduced
Lindbrook Capital, LLC178$1.00K0.00%−621−77.7%Reduced
Daiwa Securities Group Inc.138$1.00K0.00%00.0%Unchanged
Ellevest, Inc.43$00.00%+19+79.2%Added
Group One Trading, L.P.91$00.00%+91New