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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Fulcrum Therapeutics, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
101
+20 vs. Q3 2023
Shares held
61.1M
+4.69M (+8.3%) vs. Q3 2023
Total value
$412.3M
+$161.9M (+64.7%) vs. Q3 2023
New holders
31
24 more added
Sold out
11
21 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 101 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ4 2023: $412.3M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q3 2023.

Institutions holding FULC in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.11,609,704$78.4M1.22%00.0%Unchanged
FMR LLC5,684,615$38.4M0.00%−290,801−4.9%Reduced
Suvretta Capital Management, LLC5,518,881$37.3M1.70%−200,000−3.5%Reduced
RTW Investments, LP5,469,956$36.9M0.58%−348,848−6.0%Reduced
Cowen and Company, LLC3,473,934$23.4M1.54%−834,425−19.4%Reduced
Vanguard Group Inc2,519,984$17.0M0.00%−123,211−4.7%Reduced
TRV GP IV, LLC2,343,154$15.8M6.43%00.0%Unchanged
BlackRock Inc.1,561,866$10.5M0.00%+115,928+8.0%Added
Adage Capital Partners GP, L.L.C.1,506,422$10.2M0.02%−900,000−37.4%Reduced
Jefferies Financial Group Inc.1,433,316$9.67M0.15%00.0%Unchanged
Citadel Advisors LLC1,403,873$9.48M0.01%+149,689+11.9%Added
Morgan Stanley1,219,059$8.23M0.00%+307,188+33.7%Added
Logos Global Management LP1,200,000$8.10M0.90%+1,200,000New
Vestal Point Capital, LP1,025,000$6.92M0.73%+1,025,000New
Dimensional Fund Advisors LP975,279$6.58M0.00%+413,281+73.5%Added
Goldman Sachs Group Inc871,503$5.88M0.00%+612,276+236.2%Added
Deutsche Bank AG823,098$5.56M0.00%+823,098New
Propel Bio Management, LLC750,000$5.06M4.20%+750,000New
Rock Springs Capital Management LP727,673$4.91M0.12%00.0%Unchanged
Susquehanna International Group, LLP666,593$4.50M0.01%+161,252+31.9%Added
ADAR1 Capital Management, LLC637,405$4.30M1.92%+637,405New
Simplify Asset Management Inc.563,325$3.80M0.59%−7,194−1.3%Reduced
Geode Capital Management, LLC553,230$3.74M0.00%+18,727+3.5%Added
Marshall Wace, LLP505,102$3.41M0.01%−543,544−51.8%Reduced
D. E. Shaw & Co., Inc.497,679$3.36M0.00%+276,415+124.9%Added
Two Sigma Advisers, LP496,200$3.35M0.01%−25,800−4.9%Reduced
Invesco Ltd.476,206$3.21M0.00%+476,206New
Millennium Management LLC437,503$2.95M0.00%−567,179−56.5%Reduced
Schonfeld Strategic Advisors LLC432,533$2.92M0.02%+432,533New
StemPoint Capital LP376,573$2.54M0.68%+376,573New
Jane Street Group, LLC346,850$2.34M0.00%+308,349+800.9%Added
Bessemer Group Inc286,988$1.94M0.00%00.0%Unchanged
Citigroup Inc285,298$1.93M0.00%+196,109+219.9%Added
Two Sigma Investments, LP261,752$1.77M0.00%−300,371−53.4%Reduced
Standard Life Aberdeen plc256,888$1.73M0.00%+256,888New
Qube Research & Technologies Ltd242,908$1.64M0.00%+229,842+1,759.1%Added
Alliancebernstein L.P.239,458$1.62M0.00%+5,920+2.5%Added
Alyeska Investment Group, L.P.202,148$1.36M0.01%00.0%Unchanged
Bank of America Corp187,472$1.27M0.00%+48,428+34.8%Added
State Street Corp183,147$1.24M0.00%00.0%Unchanged
Susquehanna Portfolio Strategies, LLC168,775$1.14M0.02%+168,775New
Northern Trust Corp144,965$978.5K0.00%+1,984+1.4%Added
Laurion Capital Management LP144,721$976.9K0.04%+144,721New
RBF Capital, LLC140,000$945.0K0.06%−14,100−9.1%Reduced
Fiduciary Trust Co136,555$921.7K0.02%00.0%Unchanged
Acuitas Investments, LLC134,850$910.2K0.48%+390.0%Added
Opaleye Management Inc.130,000$877.5K0.24%+130,000New
Bridgeway Capital Management, LLC126,500$853.9K0.02%00.0%Unchanged
Affinity Asset Advisors, LLC125,000$843.8K0.17%+125,000New
Jacobs Levy Equity Management, Inc122,130$824.4K0.00%−143,376−54.0%Reduced
ClariVest Asset Management LLC106,977$722.1K0.04%+2,577+2.5%Added
Balyasny Asset Management LLC105,179$710.0K0.00%+105,179New
Commonwealth Equity Services, LLC96,428$651.0K0.00%+96,428New
Man Group plc94,617$638.7K0.00%+94,617New
Stifel Financial Corp71,455$482.3K0.00%+43,767+158.1%Added
Barclays PLC68,185$460.2K0.00%+68,185New
Landscape Capital Management, L.L.C.64,754$437.1K0.04%+36,502+129.2%Added
American Century Companies Inc64,623$436.2K0.00%+27,684+74.9%Added
DekaBank Deutsche Girozentrale60,000$412.0K0.00%00.0%Unchanged
Denali Advisors LLC57,800$390.1K0.12%−12,800−18.1%Reduced
ExodusPoint Capital Management, LP51,664$349.0K0.00%+51,664New
683 Capital Management, LLC46,778$315.8K0.03%+46,778New
Alps Advisors Inc39,854$269.0K0.00%+39,854New
Country Trust Bank30,186$203.8K0.01%00.0%Unchanged
UBS Group AG30,183$203.7K0.00%+19,026+170.5%Added
MYDA Advisors LLC29,370$198.2K0.09%−20,630−41.3%Reduced
Sofinnova Investments, Inc.28,600$193.1K0.01%+28,600New
Marquette Asset Management, LLC27,867$188.1K0.03%00.0%Unchanged
Brandywine Managers, LLC26,127$176.4K0.19%00.0%Unchanged
Algert Global LLC25,830$174.4K0.01%−5,180−16.7%Reduced
Brown Wealth Management, LLC25,000$168.8K0.07%00.0%Unchanged
Franklin Resources Inc24,821$167.5K0.00%−3,535−12.5%Reduced
Charles Schwab Investment Management Inc24,485$165.3K0.00%00.0%Unchanged
Group One Trading, L.P.20,359$137.4K0.00%+13,586+200.6%Added
Bank of New York Mellon Corp19,831$133.9K0.00%−41,359−67.6%Reduced
Blackstone Group Inc.19,216$129.7K0.00%00.0%Unchanged
Principal Financial Group Inc17,993$121.5K0.00%−756−4.0%Reduced
Mirabella Financial Services LLP16,914$114.2K0.02%+16,914New
Y-Intercept (Hong Kong) Ltd16,418$110.8K0.01%+16,418New
LM Advisors LLC16,132$108.9K0.02%+16,132New
Price T Rowe Associates Inc15,900$108.0K0.00%00.0%Unchanged
Bank of Montreal14,200$97.8K0.00%+14,200New
Alphabet Inc.14,262$96.3K0.00%00.0%Unchanged
Wolverine Trading, LLC13,747$92.8K0.00%+13,747New
Boothbay Fund Management, LLC11,730$79.2K0.00%+11,730New
Sherbrooke Park Advisers LLC11,684$78.9K0.04%+11,684New
JPMorgan Chase & Co11,440$77.2K0.00%+541+5.0%Added
Capstone Investment Advisors, LLC10,000$67.5K0.00%+10,000New
China Universal Asset Management Co., Ltd.7,150$48.3K0.01%+5,556+348.6%Added
PrairieView Partners, LLC5,000$34.0K0.00%00.0%Unchanged
Aquatic Capital Management LLC4,200$28.0K0.00%+4,200New
Tower Research Capital LLC (TRC)3,658$24.7K0.00%−1,589−30.3%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)2,023$13.7K0.00%00.0%Unchanged
Rhumbline Advisers1,657$11.2K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC1,542$10.4K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC790$5.33K0.00%00.0%Unchanged
National Bank of Canada460$3.31K0.00%00.0%Unchanged
Wells Fargo & Company381$2.57K0.00%+20+5.5%Added
Daiwa Securities Group Inc.138$1.00K0.00%00.0%Unchanged
Parallel Advisors, LLC44$2970.00%+44New