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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 1 sale; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q3 2022

Institutional positions in Fulcrum Therapeutics, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
105
+3 vs. Q2 2022
Shares held
52.2M
+12.2M (+30.4%) vs. Q2 2022
Total value
$422.1M
+$225.5M (+114.7%) vs. Q2 2022
New holders
24
38 more added
Sold out
21
23 more reduced

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 105 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ3 2022: $422.1M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q2 2022.

Institutions holding FULC in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC7,805,642$63.1M0.01%+1,678,411+27.4%Added
Ra Capital Management, L.P.7,000,000$56.6M1.21%+7,000,000New
RTW Investments, LP3,985,910$32.2M0.74%+24,716+0.6%Added
TRV GP III, LLC3,962,202$32.1M14.00%00.0%Unchanged
Suvretta Capital Management, LLC3,528,000$28.5M1.20%+172,376+5.1%Added
BlackRock Inc.2,772,344$22.4M0.00%+117,966+4.4%Added
Cowen and Company, LLC2,347,989$19.0M1.82%−37,896−1.6%Reduced
TRV GP IV, LLC2,343,154$19.0M11.08%00.0%Unchanged
Vanguard Group Inc1,956,092$15.8M0.00%+426,430+27.9%Added
Logos Global Management LP1,950,000$15.8M1.95%00.0%Unchanged
Point72 Asset Management, L.P.1,494,003$12.1M0.05%−494,797−24.9%Reduced
Adage Capital Partners GP, L.L.C.1,320,000$10.7M0.03%+1,050,000+388.9%Added
Morgan Stanley1,200,302$9.71M0.00%+21,346+1.8%Added
VR Adviser, LLC1,200,000$9.71M1.50%+1,200,000New
Deep Track Capital, LP900,711$7.29M0.36%−99,289−9.9%Reduced
Sofinnova Investments, Inc.797,262$6.45M0.41%+797,262New
State Street Corp725,517$5.87M0.00%+76,851+11.8%Added
Citadel Advisors LLC642,132$5.20M0.01%+586,085+1,045.7%Added
Geode Capital Management, LLC625,070$5.06M0.00%+58,557+10.3%Added
Harvard Management Co Inc410,714$3.32M0.41%00.0%Unchanged
Rock Springs Capital Management LP384,590$3.11M0.08%00.0%Unchanged
Goldman Sachs Group Inc344,730$2.79M0.00%+60,425+21.3%Added
Northern Trust Corp311,293$2.52M0.00%+2,999+1.0%Added
Perceptive Advisors LLC294,118$2.38M0.07%00.0%Unchanged
Bessemer Group Inc285,714$2.31M0.01%00.0%Unchanged
Alphabet Inc.255,452$2.07M0.11%00.0%Unchanged
Parkman Healthcare Partners LLC235,385$1.90M0.54%−27,304−10.4%Reduced
Dimensional Fund Advisors LP234,080$1.89M0.00%−128,024−35.4%Reduced
Acuta Capital Partners, LLC220,000$1.78M0.79%+20,000+10.0%Added
Monashee Investment Management LLC200,000$1.62M0.60%+200,000New
JPMorgan Chase & Co195,960$1.58M0.00%−2,155−1.1%Reduced
International Biotechnology Trust PLC193,741$1.56M0.50%+192,792+20,315.3%Added
Nuveen Asset Management, LLC158,206$1.28M0.00%−242,936−60.6%Reduced
J. Goldman & Co LP148,500$1.20M0.09%+148,500New
Fiduciary Trust Co132,472$1.07M0.02%00.0%Unchanged
Bank of New York Mellon Corp132,473$1.07M0.00%+28,053+26.9%Added
Charles Schwab Investment Management Inc92,771$751.0K0.00%+6,852+8.0%Added
Swiss National Bank89,600$725.0K0.00%+27,200+43.6%Added
Man Group plc85,758$694.0K0.00%––
D. E. Shaw & Co., Inc.82,339$666.0K0.00%−57,143−41.0%Reduced
Bridgeway Capital Management, LLC75,000$607.0K0.02%+75,000New
Schonfeld Strategic Advisors LLC66,600$539.0K0.00%+36,000+117.6%Added
State of Wisconsin Investment Board63,687$515.0K0.00%+35,403+125.2%Added
Susquehanna Fundamental Investments, LLC57,800$468.0K0.01%+57,800New
Rhumbline Advisers50,727$410.0K0.00%+3,200+6.7%Added
Two Sigma Advisers, LP50,300$407.0K0.00%−61,000−54.8%Reduced
California State Teachers Retirement System46,031$372.0K0.00%+9,330+25.4%Added
Price T Rowe Associates Inc44,605$361.0K0.00%+14,888+50.1%Added
Alliancebernstein L.P.37,600$304.0K0.00%+4,100+12.2%Added
Cubist Systematic Strategies, LLC36,541$296.0K0.00%−216,513−85.6%Reduced
Occudo Quantitative Strategies LP32,644$264.0K0.02%+1,206+3.8%Added
Stifel Financial Corp32,600$264.0K0.00%+8,000+32.5%Added
Country Trust Bank30,186$244.0K0.01%00.0%Unchanged
Bank of America Corp29,818$242.0K0.00%−73,849−71.2%Reduced
Panagora Asset Management Inc29,061$235.0K0.00%+415+1.4%Added
Voya Investment Management LLC26,909$217.7K0.00%+13,496+100.6%Added
Brandywine Managers, LLC26,127$211.0K0.69%00.0%Unchanged
Deutsche Bank AG23,730$192.0K0.00%+2,280+10.6%Added
Credit Suisse AG22,590$183.0K0.00%+1,329+6.3%Added
HRT Financial LP20,857$168.0K0.00%+20,857New
Ameriprise Financial Inc20,664$167.0K0.00%00.0%Unchanged
Marshall Wace, LLP20,115$162.0K0.00%+20,115New
MetLife Investment Management18,890$152.8K0.00%+18,890New
New York State Common Retirement Fund18,660$151.0K0.00%+105+0.6%Added
Gsa Capital Partners LLP17,879$145.0K0.02%−4,943−21.7%Reduced
Healthcare of Ontario Pension Plan Trust Fund17,000$138.0K0.00%00.0%Unchanged
American International Group, Inc.16,212$131.0K0.00%+229+1.4%Added
Ensign Peak Advisors, Inc15,610$126.0K0.00%−1,590−9.2%Reduced
Manufacturers Life Insurance Company, The15,011$121.4K0.00%+41+0.3%Added
UBS Asset Management Americas Inc14,800$119.7K0.00%00.0%Unchanged
Trexquant Investment LP13,886$112.0K0.00%+13,886New
Mirae Asset Global Investments Co., Ltd.13,552$110.0K0.00%+13,552New
Legal & General Group Plc12,859$104.0K0.00%−4,460−25.8%Reduced
SG Americas Securities, LLC11,835$96.0K0.00%−1,338−10.2%Reduced
Dynamic Technology Lab Private Ltd11,652$94.0K0.01%+11,652New
Invesco Ltd.11,241$90.0K0.00%+141+1.3%Added
Arizona State Retirement System10,280$83.0K0.00%+10,280New
Susquehanna International Group, LLP10,006$81.0K0.00%−7,681−43.4%Reduced
BNP Paribas Arbitrage, SA9,551$77.3K0.00%+9,551New
Allspring Global Investments Holdings, LLC9,176$74.0K0.00%+9,176New
Bank Julius Baer & Co. Ltd, Zurich8,366$68.0K0.00%−134−1.6%Reduced
Wells Fargo & Company5,553$45.0K0.00%−317−5.4%Reduced
Sandia Investment Management LP5,000$40.0K0.01%+5,000New
Amalgamated Bank4,028$33.0K0.00%00.0%Unchanged
PrairieView Partners, LLC3,600$29.0K0.00%+1,400+63.6%Added
Zurcher Kantonalbank (Zurich Cantonalbank)2,655$21.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,113$17.0K0.00%−3,790−64.2%Reduced
US Bancorp2,113$17.0K0.00%+2,113New
Metropolitan Life Insurance Co2,078$16.8K0.00%+2,078New
Citigroup Inc1,920$16.0K0.00%−1,820−48.7%Reduced
Ameritas Investment Partners, Inc.2,042$16.0K0.00%00.0%Unchanged
Barclays PLC1,448$12.0K0.00%−265−15.5%Reduced
Nisa Investment Advisors, LLC1,143$9.00K0.00%+920+412.6%Added
Group One Trading, L.P.880$7.00K0.00%+789+867.0%Added
Cutler Group LP500$4.00K0.00%−3,838−88.5%Reduced
National Bank of Canada460$4.00K0.00%00.0%Unchanged
Quantbot Technologies LP504$4.00K0.00%+504New
China Universal Asset Management Co., Ltd.487$4.00K0.00%+487New
Royal Bank of Canada435$3.00K0.00%+235+117.5%Added
Signaturefd, LLC356$3.00K0.00%+356New