Fulcrum Therapeutics, Inc.
FULC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001680581
In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Fulcrum Therapeutics, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 110
- +10 vs. Q3 2021
- Shares held
- 37.2M
- +742.8K (+2.0%) vs. Q3 2021
- Total value
- $657.3M
- −$371.6M (−36.1%) vs. Q3 2021
- New holders
- 34
- 41 more added
- Sold out
- 24
- 23 more reduced
1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 154 | $291.3M |
| Q1 2026 | 169 | $550.1M |
| Q4 2025 | 172 | $762.7M |
| Q3 2025 | 129 | $494.9M |
| Q2 2025 | 122 | $374.5M |
| Q1 2025 | 117 | $147.8M |
| Q4 2024 | 119 | $243.4M |
| Q3 2024 | 130 | $196.4M |
| Q2 2024 | 121 | $402.0M |
| Q1 2024 | 126 | $569.7M |
| Q4 2023 | 101 | $412.3M |
| Q3 2023 | 81 | $250.4M |
| Q2 2023 | 88 | $183.2M |
| Q1 2023 | 116 | $172.2M |
| Q4 2022 | 110 | $368.5M |
| Q3 2022 | 105 | $422.1M |
| Q2 2022 | 102 | $196.6M |
| Q1 2022 | 108 | $929.9M |
| Q4 2021 | 110 | $657.3M |
| Q3 2021 | 101 | $1.03B |
| Q2 2021 | 67 | $280.8M |
| Q1 2021 | 68 | $317.0M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 6,082,317 | $107.6M | 0.01% | +37,554+0.6% | Added |
| TRV GP III, LLC | 3,962,202 | $70.1M | 17.54% | −1,000,000−20.2% | Reduced |
| RTW Investments, LP | 3,866,872 | $68.4M | 1.00% | +11,581+0.3% | Added |
| Suvretta Capital Management, LLC | 2,375,571 | $42.0M | 0.81% | +433,602+22.3% | Added |
| TRV GP IV, LLC | 2,343,154 | $41.5M | 11.92% | 00.0% | Unchanged |
| BlackRock Inc. | 2,208,078 | $39.1M | 0.00% | +177,205+8.7% | Added |
| Adage Capital Partners GP, L.L.C. | 1,720,000 | $30.4M | 0.05% | +540,000+45.8% | Added |
| Vanguard Group Inc | 1,468,659 | $26.0M | 0.00% | +215,233+17.2% | Added |
| Holocene Advisors, LP | 864,978 | $15.3M | 0.08% | +864,978 | New |
| D. E. Shaw & Co., Inc. | 852,148 | $15.1M | 0.02% | +54,047+6.8% | Added |
| Deep Track Capital, LP | 750,000 | $13.3M | 0.98% | +750,000 | New |
| State Street Corp | 697,911 | $12.3M | 0.00% | +245,599+54.3% | Added |
| Logos Global Management LP | 685,000 | $12.1M | 1.25% | +685,000 | New |
| Sofinnova Investments, Inc. | 617,670 | $10.9M | 0.70% | +566,664+1,111.0% | Added |
| Two Sigma Investments, LP | 520,990 | $9.22M | 0.02% | −111,549−17.6% | Reduced |
| Point72 Asset Management, L.P. | 505,655 | $8.95M | 0.04% | +365,655+261.2% | Added |
| Polar Capital Holdings Plc | 500,000 | $8.85M | 0.05% | −250,000−33.3% | Reduced |
| Geode Capital Management, LLC | 498,005 | $8.81M | 0.00% | +39,563+8.6% | Added |
| Rock Springs Capital Management LP | 456,990 | $8.08M | 0.19% | +1,700+0.4% | Added |
| Harvard Management Co Inc | 410,714 | $7.27M | 0.68% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 379,100 | $6.71M | 0.02% | +236,900+166.6% | Added |
| Nuveen Asset Management, LLC | 379,646 | $5.97M | 0.00% | +247,768+187.9% | Added |
| Darwin Global Management, Ltd. | 317,428 | $5.62M | 0.86% | +283,431+833.7% | Added |
| Bessemer Group Inc | 309,421 | $5.47M | 0.01% | −1,197−0.4% | Reduced |
| Perceptive Advisors LLC | 294,118 | $5.20M | 0.08% | 00.0% | Unchanged |
| Monashee Investment Management LLC | 273,045 | $4.83M | 1.19% | +273,045 | New |
| Northern Trust Corp | 263,073 | $4.65M | 0.00% | +5,201+2.0% | Added |
| Alphabet Inc. | 255,452 | $4.52M | 0.11% | 00.0% | Unchanged |
| Parkman Healthcare Partners LLC | 250,106 | $4.42M | 1.00% | −88,690−26.2% | Reduced |
| JPMorgan Chase & Co | 202,873 | $3.59M | 0.00% | +29,146+16.8% | Added |
| Acuta Capital Partners, LLC | 200,000 | $3.54M | 1.49% | −122,500−38.0% | Reduced |
| Dimensional Fund Advisors LP | 187,521 | $3.32M | 0.00% | +136,773+269.5% | Added |
| Lord, Abbett & Co. LLC | 185,234 | $3.28M | 0.01% | −1,809−1.0% | Reduced |
| Citadel Advisors LLC | 170,961 | $3.02M | 0.00% | −142,949−45.5% | Reduced |
| Price T Rowe Associates Inc | 134,755 | $2.38M | 0.00% | +90,355+203.5% | Added |
| Fiduciary Trust Co | 132,472 | $2.34M | 0.04% | +3,257+2.5% | Added |
| Invesco Ltd. | 107,467 | $1.90M | 0.00% | −488,590−82.0% | Reduced |
| Bank of New York Mellon Corp | 100,670 | $1.78M | 0.00% | +5,639+5.9% | Added |
| HighVista Strategies LLC | 89,963 | $1.59M | 1.27% | +89,963 | New |
| Morgan Stanley | 89,550 | $1.58M | 0.00% | +4,539+5.3% | Added |
| Goldman Sachs Group Inc | 84,883 | $1.50M | 0.00% | +22,381+35.8% | Added |
| Tekla Capital Management LLC | 77,293 | $1.37M | 0.04% | +33,395+76.1% | Added |
| Allianz Asset Management GmbH | 75,525 | $1.33M | 0.00% | +34,445+83.8% | Added |
| Charles Schwab Investment Management Inc | 70,485 | $1.25M | 0.00% | +3,137+4.7% | Added |
| International Biotechnology Trust PLC | 61,000 | $1.08M | 0.24% | +61,000 | New |
| Millennium Management LLC | 58,375 | $1.03M | 0.00% | −41,332−41.5% | Reduced |
| State of Wisconsin Investment Board | 57,300 | $1.01M | 0.00% | +43,700+321.3% | Added |
| Swiss National Bank | 56,200 | $994.0K | 0.00% | +56,200 | New |
| Citigroup Inc | 40,433 | $715.0K | 0.00% | +33,118+452.7% | Added |
| HarbourVest Partners LLC | 39,511 | $699.0K | 0.09% | +39,511 | New |
| California State Teachers Retirement System | 36,704 | $649.0K | 0.00% | +22,308+155.0% | Added |
| Cinctive Capital Management LP | 36,120 | $639.0K | 0.03% | +36,120 | New |
| Schonfeld Strategic Advisors LLC | 35,500 | $628.0K | 0.01% | −46,600−56.8% | Reduced |
| Country Trust Bank | 35,186 | $622.0K | 0.02% | −2,155−5.8% | Reduced |
| Rhumbline Advisers | 31,707 | $561.0K | 0.00% | +1,508+5.0% | Added |
| Jane Street Group, LLC | 31,239 | $552.0K | 0.00% | −18,703−37.4% | Reduced |
| Prudential Financial Inc | 28,770 | $509.0K | 0.00% | +28,770 | New |
| Panagora Asset Management Inc | 28,540 | $505.0K | 0.00% | +133+0.5% | Added |
| AlphaCentric Advisors LLC | 28,500 | $504.0K | 0.15% | +28,500 | New |
| Bank of America Corp | 27,964 | $495.0K | 0.00% | +20,496+274.5% | Added |
| Deutsche Bank AG | 27,387 | $484.0K | 0.00% | −9,208−25.2% | Reduced |
| Brandywine Managers, LLC | 25,280 | $447.0K | 0.51% | +4,892+24.0% | Added |
| Cubist Systematic Strategies, LLC | 24,924 | $441.0K | 0.00% | −5,574−18.3% | Reduced |
| UNC Management Company, Inc. | 23,708 | $419.0K | 0.31% | +23,708 | New |
| Wells Fargo & Company | 22,818 | $403.0K | 0.00% | +16,959+289.5% | Added |
| Alliancebernstein L.P. | 21,600 | $382.0K | 0.00% | +5,000+30.1% | Added |
| Ergoteles LLC | 21,400 | $379.0K | 0.01% | +21,400 | New |
| Alpine Global Management, LLC | 20,905 | $370.0K | 0.05% | +20,905 | New |
| Old Mission Capital LLC | 20,670 | $366.0K | 0.02% | +20,670 | New |
| Squarepoint Ops LLC | 19,229 | $340.0K | 0.00% | +19,229 | New |
| Credit Suisse AG | 18,752 | $332.0K | 0.00% | +18,752 | New |
| New York State Common Retirement Fund | 18,585 | $329.0K | 0.00% | −13−0.1% | Reduced |
| Legal & General Group Plc | 18,258 | $323.0K | 0.00% | +16,129+757.6% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 16,742 | $298.0K | 0.00% | +16,742 | New |
| Gyon Technologies Capital Management, LP | 15,534 | $275.0K | 0.05% | +15,534 | New |
| American International Group, Inc. | 14,606 | $258.0K | 0.00% | +23+0.2% | Added |
| Manufacturers Life Insurance Company, The | 14,341 | $254.0K | 0.00% | +334+2.4% | Added |
| AQR Capital Management LLC | 14,024 | $248.0K | 0.00% | +14,024 | New |
| Marshall Wace, LLP | 13,513 | $239.0K | 0.00% | −138,176−91.1% | Reduced |
| Ensign Peak Advisors, Inc | 14,970 | $233.0K | 0.00% | +14,970 | New |
| Rafferty Asset Management, LLC | 12,971 | $229.0K | 0.00% | +12,971 | New |
| SG Americas Securities, LLC | 11,852 | $210.0K | 0.00% | −7,376−38.4% | Reduced |
| ProShare Advisors LLC | 11,712 | $208.0K | 0.00% | −311−2.6% | Reduced |
| Balyasny Asset Management LLC | 11,734 | $208.0K | 0.00% | +11,734 | New |
| Boulder Hill Capital Management LP | 11,600 | $205.0K | 0.20% | +11,600 | New |
| Jump Financial, LLC | 10,882 | $193.0K | 0.01% | +10,882 | New |
| Voya Investment Management LLC | 10,081 | $178.0K | 0.00% | −470−4.5% | Reduced |
| Virtus ETF Advisers LLC | 10,059 | $178.0K | 0.07% | +10,059 | New |
| MetLife Investment Management | 9,555 | $169.0K | 0.00% | 00.0% | Unchanged |
| Bank Julius Baer & Co. Ltd, Zurich | 8,500 | $150.0K | 0.00% | 00.0% | Unchanged |
| Hershey Trust Co | 7,903 | $140.0K | 0.00% | −26−0.3% | Reduced |
| STRS Ohio | 7,800 | $137.0K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 7,229 | $127.9K | 0.00% | 00.0% | Unchanged |
| Allspring Global Investments Holdings, LLC | 5,872 | $103.0K | 0.00% | +5,872 | New |
| Royal Bank of Canada | 4,583 | $81.0K | 0.00% | +1,343+41.5% | Added |
| Denali Advisors LLC | 3,900 | $69.0K | 0.03% | +3,900 | New |
| Tower Research Capital LLC (TRC) | 3,627 | $65.0K | 0.00% | +3,093+579.2% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 2,655 | $47.0K | 0.00% | +2,655 | New |
| Ameritas Investment Partners, Inc. | 2,042 | $36.0K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 2,360 | $29.0K | 0.00% | −3,590−60.3% | Reduced |