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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Fulcrum Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
169
−1 vs. Q4 2025
Shares held
71.7M
+7.83M (+12.3%) vs. Q4 2025
Total value
$550.1M
−$172.3M (−23.9%) vs. Q4 2025
New holders
37
74 more added
Sold out
38
38 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 169 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ1 2026: $550.1M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding FULC in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Essential Partners LLC1$80.00%00.0%Unchanged
Hughes Financial Services, LLC1$80.00%+1New
Keating Financial Advisory Services, Inc.3$230.00%−21−87.5%Reduced
SBI Securities Co., Ltd.4$310.00%00.0%Unchanged
Root Financial Partners, LLC14$1070.00%+14New
JPL Wealth Management, LLC17$1310.00%+17New
US Bancorp26$1990.00%+26New
Twin Peaks Wealth Advisors, LLC38$2910.00%+38New
True Wealth Design, LLC49$3760.00%+33+206.3%Added
SJS Investment Consulting Inc.76$5830.00%+73+2,433.3%Added
Altshuler Shaham Ltd100$7670.00%00.0%Unchanged
SRS Capital Advisors, Inc.111$8520.00%−70−38.7%Reduced
Rialto Wealth Management, LLC159$1.22K0.00%00.0%Unchanged
Basecamp Wealth Advisors LLC225$1.73K0.00%+225New
Caitong International Asset Management Co., Ltd262$2.01K0.00%+221+539.0%Added
Advisor Group Holdings, Inc.271$2.08K0.00%+181+201.1%Added
UMA Financial Services, Inc.283$2.17K0.00%00.0%Unchanged
Los Angeles Capital Management LLC295$2.26K0.00%−620−67.8%Reduced
Rothschild Investment LLC295$2.26K0.00%+287+3,587.5%Added
Federated Hermes, Inc.328$2.52K0.00%00.0%Unchanged
Larson Financial Group LLC407$3.12K0.00%+407New
EverSource Wealth Advisors, LLC409$3.14K0.00%+202+97.6%Added
National Bank of Canada422$3.23K0.00%−21−4.7%Reduced
Northwestern Mutual Wealth Management Co472$3.62K0.00%00.0%Unchanged
Optiver Holding B.V.530$4.07K0.00%+208+64.6%Added
Massmutual Trust Co FSB581$4.46K0.00%+581New
UBS Asset Management Americas Inc773$5.93K0.00%+64+9.0%Added
Versant Capital Management, Inc858$6.58K0.00%−942−52.3%Reduced
Allworth Financial LP863$6.62K0.00%+863New
The PNC Financial Services Group, Inc.885$6.79K0.00%−557−38.6%Reduced
IFP Advisors, Inc988$7.58K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.1,119$8.58K0.00%+895+399.6%Added
Zurcher Kantonalbank (Zurich Cantonalbank)1,182$9.07K0.00%+1,182New
GF Fund Management Co. Ltd.1,204$9.23K0.00%+142+13.4%Added
State of Wyoming1,815$13.9K0.00%+1,815New
Sterling Capital Management LLC1,849$14.2K0.00%−483−20.7%Reduced
MAI Capital Management1,866$14.3K0.00%+1,856+18,560.0%Added
Farther Finance Advisors, LLC2,390$17.9K0.00%+200+9.1%Added
Royal Bank of Canada2,851$21.0K0.00%−1,256−30.6%Reduced
Nisa Investment Advisors, LLC3,161$24.2K0.00%−441−12.2%Reduced
California State Teachers Retirement System3,263$25.0K0.00%+612+23.1%Added
Mirae Asset Global Investments Co., Ltd.3,474$26.6K0.00%+844+32.1%Added
Ameritas Investment Partners, Inc.4,898$37.6K0.00%+1,300+36.1%Added
Tower Research Capital LLC (TRC)6,567$50.4K0.00%+4,943+304.4%Added
Clear Street Markets LLC6,975$53.5K0.03%+6,975New
Assetmark, Inc7,525$57.7K0.00%−659−8.1%Reduced
Voya Investment Management LLC10,024$76.9K0.00%+10,024New
Entropy Technologies, LP10,819$83.0K0.00%−1,177−9.8%Reduced
Mercer Global Advisors Inc10,866$83.3K0.00%+10,866New
ProShare Advisors LLC11,656$89.4K0.00%+1,397+13.6%Added
Bailard, Inc.11,781$90.4K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.11,819$90.7K0.01%+3,000+34.0%Added
CWM, LLC12,094$92.8K0.00%+11,722+3,151.1%Added
SG Americas Securities, LLC12,139$93.0K0.00%+373+3.2%Added
New York State Common Retirement Fund13,100$100.5K0.00%−44,625−77.3%Reduced
Intech Investment Management LLC13,242$101.6K0.00%−6,505−32.9%Reduced
Renaissance Technologies LLC13,600$104.3K0.00%−3,800−21.8%Reduced
BNP Paribas Arbitrage, SA14,147$108.5K0.00%+3,625+34.5%Added
Profund Advisors LLC15,501$118.9K0.00%+15,501New
Manufacturers Life Insurance Company, The16,102$123.5K0.00%+3,219+25.0%Added
JustInvest LLC16,140$123.8K0.00%+2,982+22.7%Added
DRW Securities, LLC16,414$125.9K0.01%+16,414New
Westshore Wealth, LLC17,000$130.4K0.05%+17,000New
Legal & General Group Plc17,704$135.8K0.00%+1,331+8.1%Added
Canada Pension Plan Investment Board18,400$141.1K0.00%+18,400New
Police & Firemen's Retirement System of New Jersey18,562$142.4K0.00%+5,719+44.5%Added
Susquehanna Portfolio Strategies, LLC19,321$148.2K0.00%+19,321New
Virtus Investment Advisers, Inc.20,974$160.9K0.04%+511+2.5%Added
Axq Capital, LP22,043$169.1K0.02%−9,502−30.1%Reduced
Wells Fargo & Company22,551$173.0K0.00%−143,844−86.4%Reduced
ExodusPoint Capital Management, LP23,172$177.7K0.00%+23,172New
Mariner, LLC23,260$178.4K0.00%+23,260New
Citigroup Inc23,435$179.7K0.00%−43,667−65.1%Reduced
JPMorgan Chase & Co29,792$196.0K0.00%+9,003+43.3%Added
Quantinno Capital Management LP25,669$196.9K0.00%−3,595−12.3%Reduced
Pale Fire Capital SE26,100$200.2K0.02%+26,100New
Mirae Asset Global ETFs Holdings Ltd.28,080$215.4K0.00%+8,058+40.2%Added
LMR Partners LLP30,000$230.1K0.00%00.0%Unchanged
Country Trust Bank30,041$230.4K0.00%00.0%Unchanged
Woodline Partners LP30,793$236.2K0.00%00.0%Unchanged
Algert Global LLC33,050$253.5K0.00%+33,050New
MetLife Investment Management33,164$254.4K0.00%+10,450+46.0%Added
Seven Fleet Capital Management LP38,100$292.2K0.09%+38,100New
Vanguard Global Advisers, LLC38,519$295.4K0.00%+38,519New
Brevan Howard Capital Management LP39,444$302.5K0.00%−9,456−19.3%Reduced
Matisse Capital39,649$304.1K0.13%+26,189+194.6%Added
BIT Capital GmbH40,000$306.8K0.02%+40,000New
Commonwealth Equity Services, LLC40,290$309.0K0.00%+290+0.7%Added
Simplex Trading, LLC41,940$321.7K0.01%+33,926+423.3%Added
Marex Group plc42,000$322.1K0.00%+42,000New
Graham Capital Management, L.P.42,741$327.8K0.01%−5,723−11.8%Reduced
EntryPoint Capital, LLC45,248$347.1K0.10%+30,172+200.1%Added
Man Group plc46,119$353.7K0.00%+30,866+202.4%Added
Deutsche Bank AG48,828$374.5K0.00%−238,268−83.0%Reduced
STRS Ohio49,300$378.1K0.00%00.0%Unchanged
Burkehill Global Management, LP50,000$383.5K0.02%00.0%Unchanged
Alliancebernstein L.P.34,570$391.0K0.00%+19,300+126.4%Added
Group One Trading, L.P.53,756$412.3K0.01%+19,006+54.7%Added
Franklin Resources Inc54,666$419.3K0.00%+10,417+23.5%Added
HSBC Holdings PLC58,636$441.5K0.00%+15,374+35.5%Added