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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Fulcrum Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
117
−1 vs. Q4 2024
Shares held
51.4M
−189.6K (−0.4%) vs. Q4 2024
Total value
$147.8M
−$94.8M (−39.1%) vs. Q4 2024
New holders
18
31 more added
Sold out
19
43 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 117 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ1 2025: $147.8M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q4 2024.

Institutions holding FULC in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
CWM, LLC43$00.00%+33+330.0%Added
True Wealth Design, LLC10$290.00%+10New
SBI Securities Co., Ltd.26$750.00%00.0%Unchanged
Coldstream Capital Management Inc105$3020.00%+105New
Rialto Wealth Management, LLC159$4580.00%+159New
Russell Investments Group, Ltd.216$6220.00%−98−31.2%Reduced
The PNC Financial Services Group, Inc.526$1.51K0.00%+521+10,420.0%Added
Sterling Capital Management LLC561$1.62K0.00%−678−54.7%Reduced
UBS Asset Management Americas Inc703$2.02K0.00%+703New
Steward Partners Investment Advisory, LLC790$2.27K0.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd1,507$4.34K0.00%+1,362+939.3%Added
Farther Finance Advisors, LLC2,021$5.58K0.00%+2,021New
National Bank of Canada1,960$5.64K0.00%+1,500+326.1%Added
Amalgamated Bank2,147$6.00K0.00%00.0%Unchanged
US Bancorp2,100$6.05K0.00%+2,100New
Royal Bank of Canada2,561$7.00K0.00%−3,266−56.0%Reduced
Simplex Trading, LLC3,026$8.00K0.00%−7,429−71.1%Reduced
IFP Advisors, Inc2,812$8.10K0.00%+518+22.6%Added
Nisa Investment Advisors, LLC4,015$11.6K0.00%+2,348+140.9%Added
FMR LLC4,318$12.4K0.00%−86,147−95.2%Reduced
California State Teachers Retirement System4,496$12.9K0.00%00.0%Unchanged
PrairieView Partners, LLC5,000$14.0K0.00%00.0%Unchanged
Legal & General Group Plc5,288$15.2K0.00%−1,232−18.9%Reduced
Ameritas Investment Partners, Inc.6,079$17.5K0.00%00.0%Unchanged
Group One Trading, L.P.6,792$19.6K0.00%−22,697−77.0%Reduced
Tower Research Capital LLC (TRC)8,332$24.0K0.00%+4,357+109.6%Added
JustInvest LLC10,266$29.6K0.00%+10,266New
Jump Financial, LLC10,550$30.4K0.00%+10,550New
ProShare Advisors LLC11,657$33.6K0.00%−5,818−33.3%Reduced
CIBC World Markets Corp11,949$34.4K0.00%+11,949New
Skopos Labs, Inc.12,190$35.1K0.01%+8,254+209.7%Added
Police & Firemen's Retirement System of New Jersey12,475$35.9K0.00%00.0%Unchanged
Engineers Gate Manager LP12,519$36.1K0.00%+12,519New
Jain Global LLC13,051$37.6K0.00%−2,358−15.3%Reduced
New York State Common Retirement Fund13,100$37.7K0.00%00.0%Unchanged
Virtu Financial LLC13,564$39.0K0.00%+13,564New
Alphabet Inc.14,262$41.1K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA15,586$44.9K0.00%+7,572+94.5%Added
MetLife Investment Management17,535$50.5K0.00%−22,572−56.3%Reduced
AQR Capital Management LLC17,608$50.7K0.00%−28,033−61.4%Reduced
Voya Investment Management LLC18,548$53.4K0.00%−1,340−6.7%Reduced
J. Goldman & Co LP20,250$58.3K0.00%00.0%Unchanged
Zacks Investment Management20,999$60.5K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The22,411$64.5K0.00%−1,059−4.5%Reduced
Prudential Financial Inc22,725$65.4K0.00%+50+0.2%Added
Franklin Resources Inc24,821$71.5K0.00%00.0%Unchanged
SG Americas Securities, LLC25,375$73.0K0.00%−5,067−16.6%Reduced
Corebridge Financial, Inc.26,381$76.0K0.00%−4,469−14.5%Reduced
Country Trust Bank30,186$86.9K0.00%00.0%Unchanged
Wells Fargo & Company30,520$87.9K0.00%−3,744−10.9%Reduced
Mirae Asset Global ETFs Holdings Ltd.31,592$91.0K0.00%−4,009−11.3%Reduced
Y-Intercept (Hong Kong) Ltd32,086$92.4K0.01%+32,086New
Algert Global LLC36,147$104.1K0.00%+2,030+6.0%Added
Citigroup Inc37,829$108.9K0.00%−11,893−23.9%Reduced
Millennium Management LLC40,692$117.2K0.00%−35,431−46.5%Reduced
Intech Investment Management LLC45,689$131.6K0.00%+15,190+49.8%Added
XTX Topco Ltd49,878$143.6K0.01%+49,878New
HRT Financial LP50,490$145.0K0.00%−17,579−25.8%Reduced
Sherbrooke Park Advisers LLC55,342$159.4K0.07%+10,185+22.6%Added
Bank of America Corp56,135$161.7K0.00%−35,731−38.9%Reduced
Cubist Systematic Strategies, LLC57,070$164.4K0.00%+57,070New
Boothbay Fund Management, LLC59,533$171.5K0.01%00.0%Unchanged
Susquehanna International Group, LLP64,840$186.7K0.00%+24,063+59.0%Added
Verition Fund Management LLC65,388$188.3K0.00%−1,655−2.5%Reduced
Alliancebernstein L.P.65,590$188.9K0.00%00.0%Unchanged
Price T Rowe Associates Inc70,168$203.0K0.00%+17,800+34.0%Added
UBS Group AG71,920$207.1K0.00%−5,472−7.1%Reduced
HSBC Holdings PLC74,961$218.5K0.00%−998−1.3%Reduced
RBF Capital, LLC80,506$231.9K0.01%00.0%Unchanged
Simplify Asset Management Inc.81,134$233.7K0.01%+420+0.5%Added
Barclays PLC82,457$237.5K0.00%−39,613−32.5%Reduced
Commonwealth Equity Services, LLC83,428$240.0K0.00%00.0%Unchanged
Invesco Ltd.85,767$247.0K0.00%+55,791+186.1%Added
Rhumbline Advisers88,993$256.3K0.00%+386+0.4%Added
STRS Ohio91,200$262.7K0.00%00.0%Unchanged
Matisse Capital96,717$278.5K0.15%−31,728−24.7%Reduced
Bridgeway Capital Management, LLC97,600$281.1K0.01%−42,400−30.3%Reduced
Jane Street Group, LLC117,816$339.3K0.00%+72,657+160.9%Added
American Century Companies Inc123,711$356.3K0.00%+3,100+2.6%Added
Fiduciary Trust Co136,555$393.3K0.01%00.0%Unchanged
Bank of New York Mellon Corp143,588$413.5K0.00%+1,715+1.2%Added
Jacobs Levy Equity Management, Inc147,654$425.2K0.00%+147,654New
Two Sigma Investments, LP150,274$432.8K0.00%−19,268−11.4%Reduced
Susquehanna Fundamental Investments, LLC150,643$433.9K0.01%−62,570−29.3%Reduced
Nuveen, LLC152,992$440.6K0.00%+152,992New
Graham Capital Management, L.P.166,243$478.8K0.02%+21,301+14.7%Added
Prelude Capital Management, LLC192,207$553.6K0.06%+106,122+123.3%Added
Ikarian Capital, LLC200,096$576.3K0.19%00.0%Unchanged
Catalio Capital Management, LP202,139$582.2K0.14%+202,139New
JPMorgan Chase & Co209,893$604.5K0.00%+130,773+165.3%Added
Connor, Clark & Lunn Investment Management Ltd.217,749$627.1K0.00%−149,845−40.8%Reduced
Shay Capital LLC224,305$646.0K0.19%−77,159−25.6%Reduced
Two Sigma Advisers, LP277,800$800.1K0.00%−65,800−19.2%Reduced
Deutsche Bank AG279,812$805.9K0.00%−5,679−2.0%Reduced
Morgan Stanley285,599$822.5K0.00%−1,246,133−81.4%Reduced
Bessemer Group Inc286,988$827.0K0.00%00.0%Unchanged
Acadian Asset Management LLC344,561$989.0K0.00%+308,854+865.0%Added
Citadel Advisors LLC374,256$1.08M0.00%+40,933+12.3%Added
Charles Schwab Investment Management Inc381,359$1.10M0.00%−144,686−27.5%Reduced
Renaissance Technologies LLC401,100$1.16M0.00%+401,100New