Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 224
- +9 vs. Q3 2024
- Shares held
- 127.9M
- +1.24M (+1.0%) vs. Q3 2024
- Total value
- $2.61B
- −$1.08B (−29.3%) vs. Q3 2024
- New holders
- 41
- 87 more added
- Sold out
- 32
- 59 more reduced
2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Employees Retirement System of Texas | 43,769 | $892.0K | 0.01% | 00.0% | Unchanged |
| Skandinaviska Enskilda Banken AB (publ) | 43,245 | $875.3K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 41,825 | $852.4K | 0.00% | +9,877+30.9% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 39,757 | $810.2K | 0.00% | +10,038+33.8% | Added |
| Knights of Columbus Asset Advisors LLC | 39,217 | $799.2K | 0.05% | +98+0.3% | Added |
| Algert Global LLC | 39,015 | $795.1K | 0.02% | −9,615−19.8% | Reduced |
| Fox Run Management, L.L.C. | 38,668 | $788.1K | 0.14% | +38,668 | New |
| Victory Capital Management Inc | 38,508 | $784.8K | 0.00% | −1,392−3.5% | Reduced |
| Handelsbanken Fonder AB | 38,300 | $781.0K | 0.00% | −1,200−3.0% | Reduced |
| Teacher Retirement System of Texas | 38,178 | $778.0K | 0.00% | +5,987+18.6% | Added |
| Campbell & CO Investment Adviser LLC | 37,685 | $768.0K | 0.06% | +37,685 | New |
| Envestnet Asset Management Inc | 37,622 | $766.7K | 0.00% | +9,643+34.5% | Added |
| Arizona State Retirement System | 37,395 | $762.1K | 0.00% | +438+1.2% | Added |
| Ironwood Investment Management LLC | 36,546 | $744.8K | 0.37% | −38−0.1% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 36,006 | $733.8K | 0.05% | +22,183+160.5% | Added |
| Dana Investment Advisors, Inc. | 34,302 | $699.1K | 0.02% | −550−1.6% | Reduced |
| State Board of Administration of Florida Retirement System | 34,168 | $696.3K | 0.00% | 00.0% | Unchanged |
| HSBC Holdings PLC | 33,390 | $680.5K | 0.00% | +6,507+24.2% | Added |
| China Universal Asset Management Co., Ltd. | 30,517 | $621.9K | 0.06% | +2,982+10.8% | Added |
| Profund Advisors LLC | 28,735 | $585.6K | 0.02% | +3,877+15.6% | Added |
| Erste Asset Management GmbH | 26,900 | $554.4K | 0.01% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 26,479 | $539.6K | 0.01% | +26,479 | New |
| Raymond James Financial Inc | 26,143 | $532.8K | 0.00% | +26,143 | New |
| HighTower Advisors, LLC | 26,138 | $532.7K | 0.00% | −11,189−30.0% | Reduced |
| KLP Kapitalforvaltning AS | 26,100 | $531.9K | 0.00% | +26,100 | New |
| Walleye Capital LLC | 24,820 | $505.8K | 0.00% | +24,820 | New |
| SEI Investments Co | 24,047 | $490.1K | 0.00% | −2,229−8.5% | Reduced |
| STRS Ohio | 23,800 | $485.0K | 0.00% | +6,400+36.8% | Added |
| Cetera Investment Advisers | 22,700 | $462.6K | 0.00% | +403+1.8% | Added |
| Verition Fund Management LLC | 22,601 | $460.6K | 0.00% | +22,601 | New |
| Man Group plc | 22,435 | $457.2K | 0.00% | −7,992−26.3% | Reduced |
| Los Angeles Capital Management LLC | 22,222 | $452.9K | 0.00% | −5,718−20.5% | Reduced |
| Russell Investments Group, Ltd. | 22,116 | $450.7K | 0.00% | +142+0.6% | Added |
| Pathstone Holdings, LLC | 21,224 | $432.5K | 0.00% | +21,224 | New |
| UBS Oconnor LLC | 21,039 | $428.8K | 0.01% | −9,705−31.6% | Reduced |
| BIT Capital GmbH | 21,011 | $428.2K | 0.04% | −8,751−29.4% | Reduced |
| Graham Capital Management, L.P. | 20,706 | $422.0K | 0.01% | +8,941+76.0% | Added |
| Bryce Point Capital, LLC | 20,550 | $418.8K | 0.12% | +20,550 | New |
| Caption Management, LLC | 19,900 | $405.6K | 0.02% | +19,900 | New |
| Pictet Asset Management Holding SA | 19,356 | $394.5K | 0.00% | +2,806+17.0% | Added |
| Bayesian Capital Management, LP | 18,820 | $383.6K | 0.05% | +10,820+135.3% | Added |
| Empowered Funds, LLC | 18,587 | $378.8K | 0.01% | +18,587 | New |
| Brevan Howard Capital Management LP | 17,917 | $365.1K | 0.01% | +6,756+60.5% | Added |
| Royal Bank of Canada | 17,511 | $357.0K | 0.00% | −4,420−20.2% | Reduced |
| Ameriprise Financial Inc | 16,743 | $341.2K | 0.00% | +9,343+126.3% | Added |
| XTX Topco Ltd | 16,087 | $327.9K | 0.03% | +16,087 | New |
| BNP Paribas Arbitrage, SA | 15,943 | $324.9K | 0.00% | −11,682−42.3% | Reduced |
| Bellevue Group AG | 15,700 | $320.0K | 0.01% | 00.0% | Unchanged |
| Aquatic Capital Management LLC | 15,694 | $319.8K | 0.01% | +15,694 | New |
| VELA Investment Management, LLC | 15,635 | $318.6K | 0.11% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 15,100 | $307.7K | 0.00% | +15,100 | New |
| Great West Life Assurance Co | 13,434 | $274.0K | 0.00% | 00.0% | Unchanged |
| Dark Forest Capital Management LP | 12,888 | $262.7K | 0.04% | +12,888 | New |
| Ameritas Investment Partners, Inc. | 12,592 | $256.6K | 0.01% | 00.0% | Unchanged |
| Public Employees Retirement Association of Colorado | 12,238 | $249.0K | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Corp | 11,633 | $237.1K | 0.00% | +11,633 | New |
| JustInvest LLC | 11,377 | $231.9K | 0.00% | −1,513−11.7% | Reduced |
| Pitcairn Co | 11,298 | $230.3K | 0.01% | +39+0.3% | Added |
| Tower Research Capital LLC (TRC) | 11,288 | $230.1K | 0.00% | +10,857+2,519.0% | Added |
| SG Americas Securities, LLC | 11,003 | $224.0K | 0.00% | +6,195+128.8% | Added |
| MONECO Advisors, LLC | 10,600 | $216.0K | 0.02% | +1,500+16.5% | Added |
| E Fund Management Co., Ltd. | 9,997 | $203.7K | 0.01% | +2,436+32.2% | Added |
| Point72 (DIFC) Ltd | 7,438 | $151.6K | 0.01% | +7,383+13,423.6% | Added |
| Quest Partners LLC | 6,961 | $141.9K | 0.02% | +4,449+177.1% | Added |
| KBC Group NV | 6,334 | $129.0K | 0.00% | +2,731+75.8% | Added |
| Mirae Asset Global Investments Co., Ltd. | 4,796 | $98.8K | 0.00% | −382−7.4% | Reduced |
| Amalgamated Bank | 4,192 | $85.0K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 3,790 | $77.2K | 0.00% | +885+30.5% | Added |
| Assetmark, Inc | 3,679 | $75.0K | 0.00% | −129−3.4% | Reduced |
| Point72 Hong Kong Ltd | 3,175 | $64.7K | 0.00% | +3,175 | New |
| Virtus ETF Advisers LLC | 3,029 | $61.7K | 0.03% | −1,135−27.3% | Reduced |
| GF Fund Management Co. Ltd. | 3,022 | $61.6K | 0.00% | +3,022 | New |
| CWM, LLC | 2,402 | $49.0K | 0.00% | +249+11.6% | Added |
| GAMMA Investing LLC | 2,248 | $45.8K | 0.00% | −90−3.8% | Reduced |
| Sterling Capital Management LLC | 1,773 | $36.1K | 0.00% | +1,516+589.9% | Added |
| Advisor Group Holdings, Inc. | 1,593 | $32.5K | 0.00% | +296+22.8% | Added |
| Bartlett & Co. Wealth Management LLC | 1,500 | $30.6K | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 1,095 | $22.3K | 0.00% | +6+0.6% | Added |
| Smartleaf Asset Management LLC | 1,065 | $21.6K | 0.00% | +399+59.9% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 1,001 | $21.3K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 1,013 | $20.6K | 0.00% | −155−13.3% | Reduced |
| Nemes Rush Group LLC | 700 | $14.3K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 603 | $12.3K | 0.00% | +39+6.9% | Added |
| Huntington National Bank | 593 | $12.1K | 0.00% | +122+25.9% | Added |
| Covestor Ltd | 579 | $12.0K | 0.01% | +1+0.2% | Added |
| R Squared Ltd | 580 | $11.8K | 0.01% | +580 | New |
| Caitong International Asset Management Co., Ltd | 560 | $11.4K | 0.01% | +560 | New |
| Oarsman Capital, Inc. | 500 | $10.2K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 475 | $10.0K | 0.00% | −71−13.0% | Reduced |
| Umb Bank N A | 382 | $7.79K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 296 | $6.03K | 0.00% | −21−6.6% | Reduced |
| Private Wealth Management Group, LLC | 260 | $5.30K | 0.00% | 00.0% | Unchanged |
| Lindbrook Capital, LLC | 255 | $5.20K | 0.00% | −28−9.9% | Reduced |
| City State Bank | 250 | $5.09K | 0.00% | 00.0% | Unchanged |
| Versant Capital Management, Inc | 203 | $4.14K | 0.00% | 00.0% | Unchanged |
| Skopos Labs, Inc. | 172 | $3.51K | 0.00% | +172 | New |
| Meeder Asset Management Inc | 165 | $3.36K | 0.00% | +6+3.8% | Added |
| Massmutual Trust Co FSB | 154 | $3.14K | 0.00% | 00.0% | Unchanged |
| Activest Wealth Management | 131 | $2.67K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 117 | $2.38K | 0.00% | 00.0% | Unchanged |