Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 224
- +9 vs. Q3 2024
- Shares held
- 127.9M
- +1.24M (+1.0%) vs. Q3 2024
- Total value
- $2.61B
- −$1.08B (−29.3%) vs. Q3 2024
- New holders
- 41
- 87 more added
- Sold out
- 32
- 59 more reduced
2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Hemington Wealth Management | 11 | $0 | 0.00% | +8+266.7% | Added |
| Sandy Spring Bank | 0 | $10 | 0.00% | 0 | New |
| IFP Advisors, Inc | 1 | $20 | 0.00% | +1 | New |
| Global Financial Private Client, LLC | 2 | $41 | 0.00% | +2 | New |
| Global Retirement Partners, LLC | 3 | $61 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 5 | $102 | 0.00% | +5 | New |
| National Bank of Canada | 7 | $143 | 0.00% | −27−79.4% | Reduced |
| WealthTrak Capital Management LLC | 10 | $204 | 0.00% | +10 | New |
| Allworth Financial LP | 10 | $234 | 0.00% | +10 | New |
| Hexagon Capital Partners LLC | 12 | $245 | 0.00% | +12 | New |
| Principal Securities, Inc. | 14 | $285 | 0.00% | −9−39.1% | Reduced |
| Cassady Schiller Wealth Management, LLC | 18 | $367 | 0.00% | +18 | New |
| First Horizon Advisors, Inc. | 25 | $509 | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 25 | $510 | 0.00% | +25 | New |
| CVA Family Office, LLC | 30 | $611 | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 35 | $713 | 0.00% | −72−67.3% | Reduced |
| Bell Investment Advisors, Inc | 52 | $1.06K | 0.00% | 00.0% | Unchanged |
| Vista Private Wealth Partners. LLC | 80 | $1.63K | 0.00% | +80 | New |
| Amundi | 85 | $1.81K | 0.00% | +85 | New |
| Sherman Asset Management, Inc. | 94 | $1.92K | 0.00% | +94 | New |
| Bessemer Group Inc | 110 | $2.00K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 99 | $2.02K | 0.00% | −13−11.6% | Reduced |
| Rothschild Investment LLC | 100 | $2.04K | 0.00% | −50−33.3% | Reduced |
| Your Advocates Ltd., LLP | 100 | $2.04K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 117 | $2.38K | 0.00% | 00.0% | Unchanged |
| Activest Wealth Management | 131 | $2.67K | 0.00% | 00.0% | Unchanged |
| Massmutual Trust Co FSB | 154 | $3.14K | 0.00% | 00.0% | Unchanged |
| Meeder Asset Management Inc | 165 | $3.36K | 0.00% | +6+3.8% | Added |
| Skopos Labs, Inc. | 172 | $3.51K | 0.00% | +172 | New |
| Versant Capital Management, Inc | 203 | $4.14K | 0.00% | 00.0% | Unchanged |
| City State Bank | 250 | $5.09K | 0.00% | 00.0% | Unchanged |
| Lindbrook Capital, LLC | 255 | $5.20K | 0.00% | −28−9.9% | Reduced |
| Private Wealth Management Group, LLC | 260 | $5.30K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 296 | $6.03K | 0.00% | −21−6.6% | Reduced |
| Umb Bank N A | 382 | $7.79K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 475 | $10.0K | 0.00% | −71−13.0% | Reduced |
| Oarsman Capital, Inc. | 500 | $10.2K | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 560 | $11.4K | 0.01% | +560 | New |
| R Squared Ltd | 580 | $11.8K | 0.01% | +580 | New |
| Covestor Ltd | 579 | $12.0K | 0.01% | +1+0.2% | Added |
| Huntington National Bank | 593 | $12.1K | 0.00% | +122+25.9% | Added |
| Signaturefd, LLC | 603 | $12.3K | 0.00% | +39+6.9% | Added |
| Nemes Rush Group LLC | 700 | $14.3K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 1,013 | $20.6K | 0.00% | −155−13.3% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 1,001 | $21.3K | 0.00% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 1,065 | $21.6K | 0.00% | +399+59.9% | Added |
| Comerica Bank | 1,095 | $22.3K | 0.00% | +6+0.6% | Added |
| Bartlett & Co. Wealth Management LLC | 1,500 | $30.6K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 1,593 | $32.5K | 0.00% | +296+22.8% | Added |
| Sterling Capital Management LLC | 1,773 | $36.1K | 0.00% | +1,516+589.9% | Added |
| GAMMA Investing LLC | 2,248 | $45.8K | 0.00% | −90−3.8% | Reduced |
| CWM, LLC | 2,402 | $49.0K | 0.00% | +249+11.6% | Added |
| GF Fund Management Co. Ltd. | 3,022 | $61.6K | 0.00% | +3,022 | New |
| Virtus ETF Advisers LLC | 3,029 | $61.7K | 0.03% | −1,135−27.3% | Reduced |
| Point72 Hong Kong Ltd | 3,175 | $64.7K | 0.00% | +3,175 | New |
| Assetmark, Inc | 3,679 | $75.0K | 0.00% | −129−3.4% | Reduced |
| The PNC Financial Services Group, Inc. | 3,790 | $77.2K | 0.00% | +885+30.5% | Added |
| Amalgamated Bank | 4,192 | $85.0K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 4,796 | $98.8K | 0.00% | −382−7.4% | Reduced |
| KBC Group NV | 6,334 | $129.0K | 0.00% | +2,731+75.8% | Added |
| Quest Partners LLC | 6,961 | $141.9K | 0.02% | +4,449+177.1% | Added |
| Point72 (DIFC) Ltd | 7,438 | $151.6K | 0.01% | +7,383+13,423.6% | Added |
| E Fund Management Co., Ltd. | 9,997 | $203.7K | 0.01% | +2,436+32.2% | Added |
| MONECO Advisors, LLC | 10,600 | $216.0K | 0.02% | +1,500+16.5% | Added |
| SG Americas Securities, LLC | 11,003 | $224.0K | 0.00% | +6,195+128.8% | Added |
| Tower Research Capital LLC (TRC) | 11,288 | $230.1K | 0.00% | +10,857+2,519.0% | Added |
| Pitcairn Co | 11,298 | $230.3K | 0.01% | +39+0.3% | Added |
| JustInvest LLC | 11,377 | $231.9K | 0.00% | −1,513−11.7% | Reduced |
| CIBC World Markets Corp | 11,633 | $237.1K | 0.00% | +11,633 | New |
| Public Employees Retirement Association of Colorado | 12,238 | $249.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 12,592 | $256.6K | 0.01% | 00.0% | Unchanged |
| Dark Forest Capital Management LP | 12,888 | $262.7K | 0.04% | +12,888 | New |
| Great West Life Assurance Co | 13,434 | $274.0K | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 15,100 | $307.7K | 0.00% | +15,100 | New |
| VELA Investment Management, LLC | 15,635 | $318.6K | 0.11% | 00.0% | Unchanged |
| Aquatic Capital Management LLC | 15,694 | $319.8K | 0.01% | +15,694 | New |
| Bellevue Group AG | 15,700 | $320.0K | 0.01% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 15,943 | $324.9K | 0.00% | −11,682−42.3% | Reduced |
| XTX Topco Ltd | 16,087 | $327.9K | 0.03% | +16,087 | New |
| Ameriprise Financial Inc | 16,743 | $341.2K | 0.00% | +9,343+126.3% | Added |
| Royal Bank of Canada | 17,511 | $357.0K | 0.00% | −4,420−20.2% | Reduced |
| Brevan Howard Capital Management LP | 17,917 | $365.1K | 0.01% | +6,756+60.5% | Added |
| Empowered Funds, LLC | 18,587 | $378.8K | 0.01% | +18,587 | New |
| Bayesian Capital Management, LP | 18,820 | $383.6K | 0.05% | +10,820+135.3% | Added |
| Pictet Asset Management Holding SA | 19,356 | $394.5K | 0.00% | +2,806+17.0% | Added |
| Caption Management, LLC | 19,900 | $405.6K | 0.02% | +19,900 | New |
| Bryce Point Capital, LLC | 20,550 | $418.8K | 0.12% | +20,550 | New |
| Graham Capital Management, L.P. | 20,706 | $422.0K | 0.01% | +8,941+76.0% | Added |
| BIT Capital GmbH | 21,011 | $428.2K | 0.04% | −8,751−29.4% | Reduced |
| UBS Oconnor LLC | 21,039 | $428.8K | 0.01% | −9,705−31.6% | Reduced |
| Pathstone Holdings, LLC | 21,224 | $432.5K | 0.00% | +21,224 | New |
| Russell Investments Group, Ltd. | 22,116 | $450.7K | 0.00% | +142+0.6% | Added |
| Los Angeles Capital Management LLC | 22,222 | $452.9K | 0.00% | −5,718−20.5% | Reduced |
| Man Group plc | 22,435 | $457.2K | 0.00% | −7,992−26.3% | Reduced |
| Verition Fund Management LLC | 22,601 | $460.6K | 0.00% | +22,601 | New |
| Cetera Investment Advisers | 22,700 | $462.6K | 0.00% | +403+1.8% | Added |
| STRS Ohio | 23,800 | $485.0K | 0.00% | +6,400+36.8% | Added |
| SEI Investments Co | 24,047 | $490.1K | 0.00% | −2,229−8.5% | Reduced |
| Walleye Capital LLC | 24,820 | $505.8K | 0.00% | +24,820 | New |
| KLP Kapitalforvaltning AS | 26,100 | $531.9K | 0.00% | +26,100 | New |