Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q4 2023
Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 209
- +16 vs. Q3 2023
- Shares held
- 115.0M
- +6.57M (+6.1%) vs. Q3 2023
- Total value
- $2.47B
- +$224.9M (+10.0%) vs. Q3 2023
- New holders
- 37
- 71 more added
- Sold out
- 21
- 69 more reduced
2 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| HRT Financial LP | 44,292 | $950.0K | 0.01% | +32,087+262.9% | Added |
| Pier 88 Investment Partners LLC | 45,240 | $970.9K | 0.24% | −5,460−10.8% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 46,000 | $987.2K | 0.00% | +25,800+127.7% | Added |
| Los Angeles Capital Management LLC | 46,558 | $999.1K | 0.00% | +556+1.2% | Added |
| Bamco Inc | 50,500 | $1.08M | 0.00% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 52,692 | $1.13M | 0.00% | −75−0.1% | Reduced |
| Franklin Resources Inc | 53,201 | $1.14M | 0.00% | −6,150−10.4% | Reduced |
| Profund Advisors LLC | 53,675 | $1.15M | 0.05% | +13,521+33.7% | Added |
| American International Group, Inc. | 58,725 | $1.26M | 0.01% | −237−0.4% | Reduced |
| Harbor Capital Advisors, Inc. | 60,304 | $1.29M | 0.25% | +8,025+15.4% | Added |
| Susquehanna International Group, LLP | 60,914 | $1.31M | 0.00% | −32,889−35.1% | Reduced |
| MetLife Investment Management | 62,264 | $1.34M | 0.01% | 00.0% | Unchanged |
| Campbell & CO Investment Adviser LLC | 65,105 | $1.40M | 0.13% | +47,847+277.2% | Added |
| Nisa Investment Advisors, LLC | 66,059 | $1.42M | 0.01% | +48,099+267.8% | Added |
| DekaBank Deutsche Girozentrale | 64,210 | $1.42M | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 66,365 | $1.42M | 0.00% | −69,561−51.2% | Reduced |
| AIA Group Ltd | 68,078 | $1.46M | 0.06% | −369−0.5% | Reduced |
| Citadel Advisors LLC | 68,110 | $1.46M | 0.00% | +6,205+10.0% | Added |
| Pathway Capital Management, LP | 69,450 | $1.49M | 1.67% | +69,450 | New |
| Northwest & Ethical Investments L.P. | 71,284 | $1.53M | 0.05% | −3,484−4.7% | Reduced |
| Seven Eight Capital, LP | 72,587 | $1.56M | 0.18% | +72,587 | New |
| Mirae Asset Global Investments Co., Ltd. | 73,585 | $1.58M | 0.00% | +3,911+5.6% | Added |
| Knights of Columbus Asset Advisors LLC | 77,352 | $1.66M | 0.11% | +39,224+102.9% | Added |
| Invesco Ltd. | 79,139 | $1.70M | 0.00% | −9,214−10.4% | Reduced |
| Prudential Financial Inc | 81,244 | $1.74M | 0.00% | −72,584−47.2% | Reduced |
| TD Asset Management Inc | 91,044 | $1.95M | 0.00% | −43,956−32.6% | Reduced |
| State of Wisconsin Investment Board | 91,521 | $1.96M | 0.01% | −6,335−6.5% | Reduced |
| Alps Advisors Inc | 97,962 | $2.10M | 0.02% | −3,438−3.4% | Reduced |
| Manufacturers Life Insurance Company, The | 101,223 | $2.17M | 0.00% | −12,175−10.7% | Reduced |
| Legal & General Group Plc | 106,713 | $2.29M | 0.00% | +888+0.8% | Added |
| Russell Investments Group, Ltd. | 111,473 | $2.39M | 0.00% | −2,585−2.3% | Reduced |
| Deutsche Bank AG | 115,352 | $2.48M | 0.00% | −1,146−1.0% | Reduced |
| California State Teachers Retirement System | 117,351 | $2.52M | 0.00% | −5,553−4.5% | Reduced |
| New York State Common Retirement Fund | 123,974 | $2.66M | 0.00% | −5,879−4.5% | Reduced |
| Soleus Capital Management, L.P. | 130,000 | $2.79M | 0.31% | +130,000 | New |
| State of New Jersey Common Pension Fund D | 136,600 | $2.93M | 0.01% | +29,511+27.6% | Added |
| Alliancebernstein L.P. | 139,960 | $3.00M | 0.00% | +3,200+2.3% | Added |
| Citigroup Inc | 141,276 | $3.03M | 0.00% | +2,967+2.1% | Added |
| Neuberger Berman Group LLC | 144,461 | $3.10M | 0.00% | +144,461 | New |
| Jane Street Group, LLC | 148,965 | $3.20M | 0.00% | +110,226+284.5% | Added |
| Schroder Investment Management Group | 154,000 | $3.30M | 0.00% | +154,000 | New |
| Renaissance Technologies LLC | 161,946 | $3.48M | 0.01% | −305,905−65.4% | Reduced |
| Jefferies Financial Group Inc. | 165,327 | $3.55M | 0.06% | +152,527+1,191.6% | Added |
| Edmond de Rothschild Holding S.A. | 165,680 | $3.56M | 0.06% | +65,800+65.9% | Added |
| Rhumbline Advisers | 166,763 | $3.58M | 0.00% | −2,361−1.4% | Reduced |
| Qube Research & Technologies Ltd | 171,262 | $3.68M | 0.01% | +157,709+1,163.6% | Added |
| Pier Capital, LLC | 174,219 | $3.74M | 0.53% | +49,139+39.3% | Added |
| Hudson Bay Capital Management LP | 175,000 | $3.76M | 0.03% | +175,000 | New |
| California Public Employees Retirement System | 176,131 | $3.78M | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 183,316 | $3.93M | 0.00% | +15,352+9.1% | Added |
| BNP Paribas Arbitrage, SA | 191,643 | $4.11M | 0.01% | +28,817+17.7% | Added |
| Woodline Partners LP | 197,584 | $4.24M | 0.05% | −653,905−76.8% | Reduced |
| Teachers Retirement System of the State of Kentucky | 208,644 | $4.48M | 0.04% | −9,550−4.4% | Reduced |
| Swiss National Bank | 216,700 | $4.65M | 0.00% | −24,100−10.0% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 246,190 | $5.28M | 0.01% | −44,770−15.4% | Reduced |
| Balyasny Asset Management LLC | 260,587 | $5.59M | 0.02% | +260,587 | New |
| Voya Investment Management LLC | 284,104 | $6.10M | 0.01% | +19,488+7.4% | Added |
| UBS Group AG | 290,985 | $6.24M | 0.00% | +181,289+165.3% | Added |
| Wasatch Advisors Inc | 312,301 | $6.70M | 0.04% | −9,166−2.9% | Reduced |
| Eagle Asset Management Inc | 315,520 | $6.77M | 0.04% | +26,387+9.1% | Added |
| Nuveen Asset Management, LLC | 319,437 | $6.86M | 0.00% | −44,228−12.2% | Reduced |
| Rafferty Asset Management, LLC | 321,973 | $6.91M | 0.03% | +92,660+40.4% | Added |
| Barclays PLC | 324,019 | $6.95M | 0.00% | +157,512+94.6% | Added |
| Standard Life Aberdeen plc | 324,829 | $6.97M | 0.02% | +324,829 | New |
| Skandinaviska Enskilda Banken AB (publ) | 348,203 | $7.47M | 0.04% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 348,497 | $7.48M | 0.01% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 357,878 | $7.68M | 0.05% | 00.0% | Unchanged |
| AXA S.A. | 360,595 | $7.74M | 0.02% | +6,066+1.7% | Added |
| Clarius Group, LLC | 378,262 | $8.12M | 0.67% | 00.0% | Unchanged |
| ARCH Venture Management, LLC | 381,249 | $8.18M | 5.00% | −312,500−45.0% | Reduced |
| Artisan Partners Limited Partnership | 383,942 | $8.24M | 0.01% | −22,680−5.6% | Reduced |
| Goldman Sachs Group Inc | 393,805 | $8.45M | 0.00% | −13,588−3.3% | Reduced |
| Pictet Asset Management Holding SA | 439,218 | $9.43M | 0.01% | −150,281−25.5% | Reduced |
| Polar Capital Holdings Plc | 452,669 | $9.71M | 0.07% | −554,417−55.1% | Reduced |
| Bank of America Corp | 458,638 | $9.84M | 0.00% | +162,844+55.1% | Added |
| Braidwell LP | 461,769 | $9.91M | 0.36% | +461,769 | New |
| American Century Companies Inc | 473,494 | $10.2M | 0.01% | −842−0.2% | Reduced |
| T. Rowe Price Investment Management, Inc. | 498,969 | $10.7M | 0.01% | −148,044−22.9% | Reduced |
| Cercano Management LLC | 625,000 | $13.4M | 0.44% | 00.0% | Unchanged |
| FMR LLC | 641,653 | $13.8M | 0.00% | −416,844−39.4% | Reduced |
| Point72 Asset Management, L.P. | 644,406 | $13.8M | 0.04% | +644,406 | New |
| UBS Asset Management Americas Inc | 708,339 | $15.2M | 0.01% | +65,039+10.1% | Added |
| Artal Group S.A. | 802,899 | $17.2M | 0.59% | 00.0% | Unchanged |
| Morgan Stanley | 977,493 | $21.0M | 0.00% | −4,076−0.4% | Reduced |
| Charles Schwab Investment Management Inc | 1,006,997 | $21.6M | 0.01% | +25,938+2.6% | Added |
| Principal Financial Group Inc | 1,073,704 | $23.0M | 0.01% | +393,626+57.9% | Added |
| Northern Trust Corp | 1,101,679 | $23.6M | 0.00% | −15,063−1.3% | Reduced |
| Dimensional Fund Advisors LP | 1,119,628 | $24.0M | 0.01% | +146,394+15.0% | Added |
| Yiheng Capital Management, L.P. | 1,150,684 | $24.7M | 3.06% | 00.0% | Unchanged |
| Norges Bank | 1,152,646 | $24.7M | 0.00% | +348,754+43.4% | Added |
| Gilder Gagnon Howe & Co LLC | 1,219,392 | $26.2M | 0.36% | −26,807−2.2% | Reduced |
| Casdin Capital, LLC | 1,300,000 | $27.9M | 2.75% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 1,351,900 | $29.0M | 0.07% | 00.0% | Unchanged |
| Credit Suisse AG | 1,576,221 | $33.8M | 0.03% | +8,912+0.6% | Added |
| Marshall Wace, LLP | 1,667,397 | $35.8M | 0.07% | +1,667,397 | New |
| Bank of New York Mellon Corp | 1,870,627 | $40.1M | 0.01% | −93,061−4.7% | Reduced |
| Flagship Pioneering Inc. | 2,319,968 | $49.8M | 3.76% | −300,000−11.5% | Reduced |
| Price T Rowe Associates Inc | 2,574,321 | $55.2M | 0.01% | −317,629−11.0% | Reduced |
| Baker Bros. Advisors LP | 2,607,196 | $56.0M | 0.64% | +315,193+13.8% | Added |
| Geode Capital Management, LLC | 2,659,296 | $57.1M | 0.01% | +127,461+5.0% | Added |