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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2024

Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
213
−6 vs. Q1 2024
Shares held
74.2M
+766.8K (+1.0%) vs. Q1 2024
Total value
$2.89B
−$268.1M (−8.5%) vs. Q1 2024
New holders
21
78 more added
Sold out
27
71 more reduced

1 institution that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 213 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ2 2024: $2.89B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2024.

Institutions holding XENE in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
HRT Financial LP34,192$1.33M0.01%+1,584+4.9%Added
Rhenman & Partners Asset Management AB35,000$1.36M0.13%+35,000New
Royal Bank of Canada36,388$1.42M0.00%+1,256+3.6%Added
CIBC World Markets Inc.36,385$1.42M0.00%−935−2.5%Reduced
DekaBank Deutsche Girozentrale39,000$1.46M0.00%00.0%Unchanged
Artia Global Partners LP40,000$1.56M0.40%00.0%Unchanged
Skandinaviska Enskilda Banken AB (publ)40,376$1.57M0.01%+40,376New
Trexquant Investment LP40,847$1.59M0.02%−6,027−12.9%Reduced
Thrivent Financial for Lutherans43,093$1.68M0.00%+43,093New
Northern Trust Corp46,852$1.83M0.00%−1,618−3.3%Reduced
Voya Investment Management LLC47,165$1.84M0.00%−17,775−27.4%Reduced
Qube Research & Technologies Ltd47,842$1.87M0.00%+2,556+5.6%Added
Erste Asset Management GmbH50,000$1.87M0.02%00.0%Unchanged
Jump Financial, LLC48,166$1.88M0.04%+2,087+4.5%Added
State of New Jersey Common Pension Fund D48,573$1.89M0.01%−8,177−14.4%Reduced
LMR Partners LLP48,668$1.90M0.04%00.0%Unchanged
Envestnet Asset Management Inc48,946$1.91M0.00%+769+1.6%Added
Bank of New York Mellon Corp51,254$2.00M0.00%−15,656−23.4%Reduced
Prudential Financial Inc52,000$2.03M0.00%−7,000−11.9%Reduced
Deutsche Bank AG53,711$2.09M0.00%+15,000+38.7%Added
Moore Capital Management, LP55,000$2.14M0.05%00.0%Unchanged
Legal & General Group Plc55,120$2.15M0.00%+110+0.2%Added
California State Teachers Retirement System58,140$2.27M0.00%+1,663+2.9%Added
Alps Advisors Inc58,853$2.29M0.02%+5,653+10.6%Added
Wells Fargo & Company59,067$2.30M0.00%−2,390−3.9%Reduced
Geode Capital Management, LLC68,929$2.69M0.00%+4,700+7.3%Added
Jefferies Financial Group Inc.69,000$2.69M0.05%+3,363+5.1%Added
JPMorgan Chase & Co71,654$2.79M0.00%+35,033+95.7%Added
HighVista Strategies LLC72,715$2.84M1.04%00.0%Unchanged
Assenagon Asset Management S.A.73,602$2.87M0.01%−113,004−60.6%Reduced
Twinbeech Capital LP88,711$3.46M0.07%−9,331−9.5%Reduced
State of Wisconsin Investment Board89,800$3.50M0.01%−1,985−2.2%Reduced
Schroder Investment Management Group91,500$3.57M0.00%00.0%Unchanged
Renaissance Technologies LLC92,900$3.62M0.01%+36,500+64.7%Added
Bamco Inc100,100$3.90M0.01%00.0%Unchanged
Tri Locum Partners LP101,959$3.98M1.01%−105,506−50.9%Reduced
Nan Fung Group Holdings Ltd106,680$4.16M4.44%00.0%Unchanged
Ikarian Capital, LLC107,187$4.18M1.30%00.0%Unchanged
Atika Capital Management LLC124,000$4.83M0.56%+2,000+1.6%Added
Swiss National Bank126,100$4.92M0.00%+2,300+1.9%Added
Bank of America Corp142,332$5.55M0.00%−14,772−9.4%Reduced
Bridger Management, LLC146,800$5.72M2.95%00.0%Unchanged
PFM Health Sciences, LP150,554$5.87M0.32%00.0%Unchanged
New York State Common Retirement Fund150,840$5.88M0.01%−41,912−21.7%Reduced
D. E. Shaw & Co., Inc.161,722$6.31M0.01%−36,804−18.5%Reduced
UBS Asset Management Americas Inc162,466$6.33M0.00%+84,982+109.7%Added
Russell Investments Group, Ltd.162,850$6.35M0.01%−15,249−8.6%Reduced
Ensign Peak Advisors, Inc163,064$6.36M0.01%00.0%Unchanged
Ally Bridge Group (NY) LLC169,369$6.60M3.93%−140,000−45.3%Reduced
Laurion Capital Management LP171,195$6.67M0.22%−67,931−28.4%Reduced
Millennium Management LLC175,584$6.85M0.01%+91,923+109.9%Added
DnB Asset Management AS175,733$6.85M0.03%+49,483+39.2%Added
Algert Global LLC183,205$7.14M0.24%−810−0.4%Reduced
AXA S.A.188,038$7.33M0.02%+166+0.1%Added
Lord, Abbett & Co. LLC190,033$7.41M0.02%−705,163−78.8%Reduced
Two Sigma Investments, LP195,129$7.61M0.02%−79,497−28.9%Reduced
Two Sigma Advisers, LP208,900$8.15M0.02%−20,300−8.9%Reduced
Parkman Healthcare Partners LLC209,290$8.16M1.11%−14,652−6.5%Reduced
Standard Life Aberdeen plc212,502$8.29M0.02%+180,466+563.3%Added
Granahan Investment Management Inc226,166$8.82M0.35%−17,914−7.3%Reduced
Balyasny Asset Management LLC233,335$9.10M0.02%+32,061+15.9%Added
Morgan Stanley238,772$9.31M0.00%−147,427−38.2%Reduced
State Street Corp246,812$9.62M0.00%+4,172+1.7%Added
Boone Capital Management LLC250,460$9.77M2.55%−40,943−14.1%Reduced
DAFNA Capital Management LLC273,739$10.7M2.55%00.0%Unchanged
Alyeska Investment Group, L.P.291,868$11.4M0.07%+53,025+22.2%Added
First Turn Management, LLC339,876$13.3M2.16%−340,513−50.0%Reduced
Vanguard Group Inc341,152$13.3M0.00%+5,517+1.6%Added
ExodusPoint Capital Management, LP357,178$13.9M0.15%+203,140+131.9%Added
Altium Capital Management LP360,600$14.1M5.81%+12,600+3.6%Added
Goldman Sachs Group Inc364,173$14.2M0.00%+64,399+21.5%Added
Logos Global Management LP375,000$14.6M1.68%+375,000New
Artal Group S.A.381,554$14.9M0.38%+128,167+50.6%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.421,121$16.4M0.04%+4,385+1.1%Added
Dimensional Fund Advisors LP436,460$17.0M0.00%+26,253+6.4%Added
Point72 Asset Management, L.P.482,022$18.8M0.06%+206,163+74.7%Added
Candriam Luxembourg S.C.A.521,836$20.3M0.12%−39,048−7.0%Reduced
Vestal Point Capital, LP525,000$20.5M1.53%+125,000+31.3%Added
Jennison Associates LLC570,272$22.2M0.01%+6,320+1.1%Added
Franklin Resources Inc578,865$22.6M0.01%+36,576+6.7%Added
Fiera Capital Corp582,879$22.7M0.07%+6,337+1.1%Added
Perceptive Advisors LLC583,256$22.7M0.55%−308,952−34.6%Reduced
Boxer Capital, LLC600,000$23.4M1.23%00.0%Unchanged
Samlyn Capital, LLC639,685$24.9M0.43%+243,489+61.5%Added
Westfield Capital Management Co LP643,546$25.1M0.12%+296,195+85.3%Added
Loomis Sayles & Co L P660,258$25.7M0.04%−26,252−3.8%Reduced
Federated Hermes, Inc.734,555$28.6M0.07%−3450.0%Reduced
Avidity Partners Management LP754,000$29.4M1.25%+44,000+6.2%Added
TimesSquare Capital Management, LLC754,493$29.4M0.46%+17,320+2.3%Added
Citadel Advisors LLC768,726$30.0M0.03%−518,349−40.3%Reduced
OrbiMed Advisors LLC862,362$33.6M0.72%+312,362+56.8%Added
Invesco Ltd.866,785$33.8M0.01%−182,741−17.4%Reduced
Baker Bros. Advisors LP993,679$38.7M0.50%00.0%Unchanged
Affinity Asset Advisors, LLC994,227$38.8M6.11%+156,840+18.7%Added
Janus Henderson Group PLC1,045,257$40.8M0.02%+103,688+11.0%Added
Rock Springs Capital Management LP1,272,877$49.6M1.50%+17,300+1.4%Added
First Light Asset Management, LLC1,306,260$50.9M4.46%−13,912−1.1%Reduced
Marshall Wace, LLP1,384,674$54.0M0.08%−65,668−4.5%Reduced
T. Rowe Price Investment Management, Inc.1,439,903$56.1M0.04%+13,564+1.0%Added
Pictet Asset Management Holding SA1,479,491$57.7M0.07%−35,935−2.4%Reduced