Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q1 2024
Institutional positions in Tyra Biosciences, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 77
- +15 vs. Q4 2023
- Shares held
- 46.9M
- +11.1M (+31.0%) vs. Q4 2023
- Total value
- $768.4M
- +$273.2M (+55.2%) vs. Q4 2023
- New holders
- 22
- 25 more added
- Sold out
- 7
- 16 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 10,416,609 | $170.8M | 2.17% | +3,180,155+43.9% | Added |
| Boxer Capital, LLC | 6,448,359 | $105.8M | 5.22% | 00.0% | Unchanged |
| BVF Inc | 4,661,194 | $76.4M | 2.10% | +1,921,599+70.1% | Added |
| Canaan Partners XI LLC | 4,409,991 | $72.3M | 79.77% | 00.0% | Unchanged |
| Nextech Invest AG | 4,055,861 | $66.5M | 10.54% | +1,537,279+61.0% | Added |
| FMR LLC | 3,977,208 | $65.2M | 0.00% | +1,208,512+43.6% | Added |
| TCG Crossover Management, LLC | 1,989,103 | $32.6M | 2.58% | 00.0% | Unchanged |
| Fairmount Funds Management LLC | 1,393,329 | $22.9M | 2.49% | 00.0% | Unchanged |
| BlackRock Inc. | 1,044,225 | $17.1M | 0.00% | +79,191+8.2% | Added |
| 5AM Venture Management, LLC | 939,298 | $15.4M | 3.45% | +384,319+69.2% | Added |
| Vanguard Group Inc | 899,800 | $14.8M | 0.00% | +140,833+18.6% | Added |
| Frazier Life Sciences Management, L.P. | 832,220 | $13.6M | 0.58% | −194,200−18.9% | Reduced |
| OrbiMed Advisors LLC | 768,638 | $12.6M | 0.25% | +768,638 | New |
| Perceptive Advisors LLC | 669,159 | $11.0M | 0.19% | +309,159+85.9% | Added |
| Sio Capital Management, LLC | 535,741 | $8.79M | 3.06% | +535,741 | New |
| Kynam Capital Management, LP | 515,190 | $8.45M | 0.94% | +175,000+51.4% | Added |
| Geode Capital Management, LLC | 416,808 | $6.84M | 0.00% | +83,339+25.0% | Added |
| First Turn Management, LLC | 381,210 | $6.25M | 0.94% | +381,210 | New |
| JPMorgan Chase & Co | 380,597 | $6.24M | 0.00% | −21,109−5.3% | Reduced |
| State Street Corp | 292,234 | $4.79M | 0.00% | +26,880+10.1% | Added |
| ExodusPoint Capital Management, LP | 272,150 | $4.46M | 0.06% | +272,150 | New |
| Driehaus Capital Management LLC | 203,709 | $3.34M | 0.03% | 00.0% | Unchanged |
| Northern Trust Corp | 156,472 | $2.57M | 0.00% | +4,222+2.8% | Added |
| Nicholas Investment Partners, LP | 152,968 | $2.51M | 0.26% | +152,968 | New |
| Charles Schwab Investment Management Inc | 152,212 | $2.50M | 0.00% | +41,675+37.7% | Added |
| Wellington Management Group LLP | 101,788 | $1.67M | 0.00% | −648−0.6% | Reduced |
| Auour Investments LLC | 85,020 | $1.39M | 0.51% | 00.0% | Unchanged |
| Oppenheimer & Co Inc | 59,576 | $977.0K | 0.02% | +59,576 | New |
| Renaissance Technologies LLC | 54,400 | $892.0K | 0.00% | +54,400 | New |
| Victory Capital Management Inc | 48,090 | $788.7K | 0.00% | −2,130−4.2% | Reduced |
| Bank of New York Mellon Corp | 43,735 | $717.3K | 0.00% | +1,790+4.3% | Added |
| Two Sigma Investments, LP | 41,742 | $684.6K | 0.00% | +41,742 | New |
| Morgan Stanley | 35,237 | $577.9K | 0.00% | −431−1.2% | Reduced |
| Bank of America Corp | 33,032 | $541.7K | 0.00% | +10,914+49.3% | Added |
| New York State Common Retirement Fund | 32,149 | $527.2K | 0.00% | +28,118+697.5% | Added |
| ADAR1 Capital Management, LLC | 28,300 | $464.1K | 0.13% | +28,300 | New |
| Nuveen Asset Management, LLC | 25,713 | $421.7K | 0.00% | 00.0% | Unchanged |
| American Century Companies Inc | 24,937 | $409.0K | 0.00% | +14,057+129.2% | Added |
| Rhumbline Advisers | 20,998 | $344.4K | 0.00% | −334−1.6% | Reduced |
| Legato Capital Management LLC | 20,259 | $332.2K | 0.04% | +20,259 | New |
| Marshall Wace, LLP | 19,643 | $322.1K | 0.00% | −10,358−34.5% | Reduced |
| Walleye Capital LLC | 16,887 | $276.9K | 0.00% | +16,887 | New |
| Citadel Advisors LLC | 16,789 | $275.3K | 0.00% | +16,789 | New |
| Exchange Traded Concepts, LLC | 16,053 | $263.3K | 0.01% | +6,522+68.4% | Added |
| Jump Financial, LLC | 15,159 | $248.6K | 0.01% | +15,159 | New |
| Fishman Jay A Ltd | 15,000 | $246.0K | 0.03% | +15,000 | New |
| UBS Group AG | 14,172 | $232.4K | 0.00% | +9,195+184.7% | Added |
| Goldman Sachs Group Inc | 14,077 | $230.9K | 0.00% | +14,077 | New |
| Hudson Bay Capital Management LP | 13,317 | $218.4K | 0.00% | +13,317 | New |
| PDT Partners, LLC | 12,174 | $199.7K | 0.02% | +12,174 | New |
| Dimensional Fund Advisors LP | 10,750 | $176.3K | 0.00% | +141+1.3% | Added |
| Baker Bros. Advisors LP | 10,607 | $174.0K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 9,850 | $161.5K | 0.00% | −9,377−48.8% | Reduced |
| MetLife Investment Management | 7,702 | $126.3K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 7,106 | $116.5K | 0.00% | +5,075+249.9% | Added |
| Qube Research & Technologies Ltd | 7,032 | $115.3K | 0.00% | +4,379+165.1% | Added |
| American International Group, Inc. | 6,892 | $113.0K | 0.00% | −59−0.8% | Reduced |
| Deutsche Bank AG | 6,013 | $98.6K | 0.00% | −210−3.4% | Reduced |
| Wells Fargo & Company | 4,725 | $77.5K | 0.00% | +652+16.0% | Added |
| California State Teachers Retirement System | 1,406 | $23.1K | 0.00% | −896−38.9% | Reduced |
| EntryPoint Capital, LLC | 1,345 | $22.1K | 0.02% | +1,345 | New |
| Legal & General Group Plc | 1,265 | $20.7K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 940 | $15.4K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 814 | $13.3K | 0.00% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 713 | $11.7K | 0.00% | −1,357−65.6% | Reduced |
| STRS Ohio | 700 | $11.0K | 0.00% | +700 | New |
| Ikarian Capital, LLC | 501 | $8.22K | 0.00% | −47,669−99.0% | Reduced |
| Amalgamated Bank | 424 | $7.00K | 0.00% | −1,021−70.7% | Reduced |
| Royal Bank of Canada | 320 | $5.00K | 0.00% | −3,924−92.5% | Reduced |
| Tower Research Capital LLC (TRC) | 144 | $2.36K | 0.00% | −860−85.7% | Reduced |
| Russell Investments Group, Ltd. | 126 | $2.07K | 0.00% | +107+563.2% | Added |
| Simplex Trading, LLC | 100 | $1.00K | 0.00% | +100 | New |
| The PNC Financial Services Group, Inc. | 58 | $951 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 34 | $558 | 0.00% | +18+112.5% | Added |
| GAMMA Investing LLC | 16 | $262 | 0.00% | 00.0% | Unchanged |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 2 | $32 | 0.00% | +2 | New |
| CWM, LLC | 1 | $0 | 0.00% | +1 | New |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −137,014−100.0% | Sold out |
| Mariner, LLC | 0 | $0 | 0.00% | −22,164−100.0% | Sold out |
| Sepio Capital, LP | 0 | $0 | 0.00% | −10,625−100.0% | Sold out |
| LPL Financial LLC | 0 | $0 | 0.00% | −10,500−100.0% | Sold out |
| Artia Global Partners LP | 0 | $0 | 0.00% | −10,253−100.0% | Sold out |
| Acuta Capital Partners, LLC | 0 | $0 | 0.00% | −8,867−100.0% | Sold out |
| AJOVista, LLC | 0 | $0 | 0.00% | −4,235−100.0% | Sold out |