Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Tyra Biosciences, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 113
- +18 vs. Q3 2024
- Shares held
- 48.6M
- +1.56M (+3.3%) vs. Q3 2024
- Total value
- $675.8M
- −$430.2M (−38.9%) vs. Q3 2024
- New holders
- 36
- 34 more added
- Sold out
- 18
- 25 more reduced
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 10,637,290 | $147.9M | 1.97% | +220,681+2.1% | Added |
| Canaan Partners XI LLC | 4,179,857 | $58.1M | 75.17% | −230,134−5.2% | Reduced |
| Alta Partners Management Company, L.P. | 4,080,296 | $56.7M | 89.47% | +4,080,296 | New |
| Nextech Invest AG | 4,055,861 | $56.4M | 9.15% | 00.0% | Unchanged |
| BVF Inc | 3,944,194 | $54.8M | 1.86% | −717,000−15.4% | Reduced |
| FMR LLC | 3,107,970 | $43.2M | 0.00% | −264,880−7.9% | Reduced |
| Boxer Capital Management, LLC | 2,027,678 | $28.2M | 2.40% | +2,027,678 | New |
| TCG Crossover Management, LLC | 1,989,103 | $27.6M | 2.70% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 1,746,320 | $24.3M | 0.01% | +679,124+63.6% | Added |
| BlackRock, Inc. | 1,718,504 | $23.9M | 0.00% | +202,332+13.3% | Added |
| OrbiMed Advisors LLC | 1,470,086 | $20.4M | 0.42% | +701,448+91.3% | Added |
| Vanguard Group Inc | 1,207,765 | $16.8M | 0.00% | −37,643−3.0% | Reduced |
| Farallon Capital Management, L.L.C. | 1,000,981 | $13.9M | 0.07% | +1,000,981 | New |
| Vestal Point Capital, LP | 990,000 | $13.8M | 0.82% | +990,000 | New |
| 5AM Venture Management, LLC | 939,298 | $13.1M | 3.12% | 00.0% | Unchanged |
| Kynam Capital Management, LP | 530,478 | $7.37M | 0.49% | +62,531+13.4% | Added |
| Geode Capital Management, LLC | 517,578 | $7.20M | 0.00% | −5,612−1.1% | Reduced |
| State Street Corp | 407,573 | $5.67M | 0.00% | +22,841+5.9% | Added |
| Pictet Asset Management Holding SA | 354,012 | $4.92M | 0.01% | +354,012 | New |
| Millennium Management LLC | 315,141 | $4.38M | 0.00% | +304,637+2,900.2% | Added |
| Jacobs Levy Equity Management, Inc | 244,245 | $3.40M | 0.01% | +244,245 | New |
| Sio Capital Management, LLC | 240,870 | $3.35M | 0.94% | −160,000−39.9% | Reduced |
| Northern Trust Corp | 222,764 | $3.10M | 0.00% | +8,411+3.9% | Added |
| Adage Capital Partners GP, L.L.C. | 200,000 | $2.78M | 0.00% | 00.0% | Unchanged |
| Ally Bridge Group (NY) LLC | 175,063 | $2.43M | 2.09% | −95,012−35.2% | Reduced |
| Charles Schwab Investment Management Inc | 170,600 | $2.37M | 0.00% | −3,137−1.8% | Reduced |
| Polar Asset Management Partners Inc. | 111,107 | $1.54M | 0.02% | +23,007+26.1% | Added |
| Cubist Systematic Strategies, LLC | 109,748 | $1.53M | 0.02% | +109,748 | New |
| Nantahala Capital Management, LLC | 100,000 | $1.39M | 0.10% | +100,000 | New |
| Wellington Management Group LLP | 94,859 | $1.32M | 0.00% | +4,034+4.4% | Added |
| JPMorgan Chase & Co | 91,115 | $1.27M | 0.00% | −277,532−75.3% | Reduced |
| Investment Counsel Co of Nevada | 85,020 | $1.18M | 3.00% | +85,020 | New |
| Oppenheimer & Co Inc | 75,439 | $1.05M | 0.02% | −1,367−1.8% | Reduced |
| Morgan Stanley | 74,149 | $1.03M | 0.00% | +5,233+7.6% | Added |
| Bank of America Corp | 66,157 | $919.6K | 0.00% | +11,804+21.7% | Added |
| State of Wisconsin Investment Board | 65,039 | $904.0K | 0.00% | +29,473+82.9% | Added |
| Goldman Sachs Group Inc | 64,110 | $891.1K | 0.00% | −24,971−28.0% | Reduced |
| Walleye Capital LLC | 62,980 | $875.4K | 0.01% | −63,617−50.3% | Reduced |
| Ikarian Capital, LLC | 60,000 | $834.0K | 0.24% | +60,000 | New |
| Victory Capital Management Inc | 56,640 | $787.3K | 0.00% | +26,560+88.3% | Added |
| Citadel Advisors LLC | 55,587 | $772.7K | 0.00% | +31,635+132.1% | Added |
| Raymond James Financial Inc | 54,783 | $761.5K | 0.00% | +54,783 | New |
| Marshall Wace, LLP | 54,077 | $751.7K | 0.00% | +34,463+175.7% | Added |
| Nuveen Asset Management, LLC | 49,998 | $695.0K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 47,851 | $665.1K | 0.00% | +36,887+336.4% | Added |
| Two Sigma Investments, LP | 46,269 | $643.1K | 0.00% | +7,093+18.1% | Added |
| Bank of New York Mellon Corp | 45,007 | $625.6K | 0.00% | +2,221+5.2% | Added |
| Barclays PLC | 43,070 | $598.7K | 0.00% | +5,445+14.5% | Added |
| Susquehanna Fundamental Investments, LLC | 39,093 | $543.4K | 0.01% | +39,093 | New |
| Dimensional Fund Advisors LP | 37,981 | $527.9K | 0.00% | +28,074+283.4% | Added |
| UBS Asset Management Americas Inc | 35,635 | $495.3K | 0.00% | +10,426+41.4% | Added |
| Renaissance Technologies LLC | 29,100 | $404.5K | 0.00% | +29,100 | New |
| Rhumbline Advisers | 26,202 | $364.2K | 0.00% | +1,027+4.1% | Added |
| HighVista Strategies LLC | 23,941 | $332.8K | 0.12% | +7,863+48.9% | Added |
| American Century Companies Inc | 22,142 | $307.8K | 0.00% | −20,857−48.5% | Reduced |
| Auour Investments LLC | 21,020 | $303.9K | 0.11% | 00.0% | Unchanged |
| Swiss National Bank | 20,700 | $287.7K | 0.00% | −5,000−19.5% | Reduced |
| PDT Partners, LLC | 20,359 | $283.0K | 0.03% | +20,359 | New |
| Deutsche Bank AG | 18,909 | $262.8K | 0.00% | +6,466+52.0% | Added |
| Squarepoint Ops LLC | 18,216 | $253.2K | 0.00% | +18,216 | New |
| EntryPoint Capital, LLC | 18,209 | $253.1K | 0.11% | +18,209 | New |
| Alliancebernstein L.P. | 17,570 | $244.2K | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 17,560 | $244.1K | 0.01% | +17,560 | New |
| Citigroup Inc | 16,803 | $233.6K | 0.00% | +2,136+14.6% | Added |
| Tudor Investment Corp Et Al | 15,577 | $216.5K | 0.00% | −10,769−40.9% | Reduced |
| Jump Financial, LLC | 15,160 | $210.7K | 0.00% | +15,160 | New |
| Manufacturers Life Insurance Company, The | 13,368 | $185.8K | 0.00% | −816−5.8% | Reduced |
| Point72 Asset Management, L.P. | 12,783 | $177.7K | 0.00% | +12,783 | New |
| Franklin Resources Inc | 12,751 | $177.2K | 0.00% | +104+0.8% | Added |
| Two Sigma Advisers, LP | 12,300 | $171.0K | 0.00% | +12,300 | New |
| MetLife Investment Management | 12,207 | $169.7K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 11,641 | $161.8K | 0.00% | +532+4.8% | Added |
| China Universal Asset Management Co., Ltd. | 10,730 | $149.1K | 0.01% | +10,730 | New |
| Baker Bros. Advisors LP | 10,607 | $147.4K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 10,570 | $146.9K | 0.00% | −2,366−18.3% | Reduced |
| Russell Investments Group, Ltd. | 10,455 | $145.3K | 0.00% | +10,447+130,587.5% | Added |
| Corebridge Financial, Inc. | 10,102 | $140.4K | 0.00% | −762−7.0% | Reduced |
| SG Americas Securities, LLC | 9,671 | $134.0K | 0.00% | −3,540−26.8% | Reduced |
| Wells Fargo & Company | 9,493 | $132.0K | 0.00% | +3,236+51.7% | Added |
| Legal & General Group Plc | 9,340 | $129.8K | 0.00% | 00.0% | Unchanged |
| Exchange Traded Concepts, LLC | 8,311 | $115.5K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 7,423 | $103.2K | 0.00% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 5,049 | $70.2K | 0.00% | +5,049 | New |
| Quest Partners LLC | 5,023 | $69.8K | 0.01% | −15,855−75.9% | Reduced |
| Virtus ETF Advisers LLC | 4,686 | $65.1K | 0.03% | +44+0.9% | Added |
| Aquatic Capital Management LLC | 4,586 | $63.7K | 0.00% | +4,586 | New |
| BNP Paribas Arbitrage, SA | 4,318 | $60.0K | 0.00% | +4,318 | New |
| US Bancorp | 3,612 | $50.2K | 0.00% | +3,612 | New |
| KLP Kapitalforvaltning AS | 2,200 | $30.6K | 0.00% | +2,200 | New |
| Ameritas Investment Partners, Inc. | 1,991 | $27.7K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 1,686 | $23.7K | 0.00% | +1,686 | New |
| R Squared Ltd | 1,480 | $20.6K | 0.02% | +1,480 | New |
| Tower Research Capital LLC (TRC) | 1,417 | $19.7K | 0.00% | +206+17.0% | Added |
| GF Fund Management Co. Ltd. | 1,063 | $14.8K | 0.00% | +1,063 | New |
| Federated Hermes, Inc. | 1,028 | $14.3K | 0.00% | +98+10.5% | Added |
| Royal Bank of Canada | 774 | $11.0K | 0.00% | −1,361−63.7% | Reduced |
| STRS Ohio | 700 | $9.73K | 0.00% | 00.0% | Unchanged |
| Point72 (DIFC) Ltd | 561 | $7.79K | 0.00% | +561 | New |
| Amalgamated Bank | 424 | $6.00K | 0.00% | 00.0% | Unchanged |
| Aster Capital Management (DIFC) Ltd | 214 | $2.98K | 0.00% | +214 | New |