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Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

13F holders, Q3 2023

Institutional positions in Tyra Biosciences, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
59
0 vs. Q2 2023
Shares held
36.5M
+251.8K (+0.7%) vs. Q2 2023
Total value
$502.1M
−$114.6M (−18.6%) vs. Q2 2023
New holders
4
16 more added
Sold out
4
16 more reduced

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 59 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 26 institutionsQ4 2021: 45 institutionsQ1 2022: 46 institutionsQ2 2022: 48 institutionsQ3 2022: 49 institutionsQ4 2022: 46 institutionsQ1 2023: 51 institutionsQ2 2023: 59 institutionsQ3 2023: 59 institutionsQ4 2023: 62 institutionsQ1 2024: 77 institutionsQ2 2024: 79 institutionsQ3 2024: 95 institutionsQ4 2024: 113 institutionsQ1 2025: 117 institutionsQ2 2025: 121 institutionsQ3 2025: 116 institutionsQ4 2025: 133 institutionsQ1 2026: 164 institutionsQ2 2026: 168 institutions
Value heldQ3 2023: $502.1M
Q1 2021: $0Q2 2021: $0Q3 2021: $456.8MQ4 2021: $494.2MQ1 2022: $386.6MQ2 2022: $255.6MQ3 2022: $313.8MQ4 2022: $267.8MQ1 2023: $573.0MQ2 2023: $616.7MQ3 2023: $502.1MQ4 2023: $495.2MQ1 2024: $768.4MQ2 2024: $748.6MQ3 2024: $1.11BQ4 2024: $675.8MQ1 2025: $499.5MQ2 2025: $541.5MQ3 2025: $778.4MQ4 2025: $1.49BQ1 2026: $2.52BQ2 2026: $2.22B
Institutions holding TYRA and their total value by quarter
QuarterHoldersValue
Q2 2026168$2.22B
Q1 2026164$2.52B
Q4 2025133$1.49B
Q3 2025116$778.4M
Q2 2025121$541.5M
Q1 2025117$499.5M
Q4 2024113$675.8M
Q3 202495$1.11B
Q2 202479$748.6M
Q1 202477$768.4M
Q4 202362$495.2M
Q3 202359$502.1M
Q2 202359$616.7M
Q1 202351$573.0M
Q4 202246$267.8M
Q3 202249$313.8M
Q2 202248$255.6M
Q1 202246$386.6M
Q4 202145$494.2M
Q3 202126$456.8M
Q2 20210$0
Q1 20210$0

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q2 2023.

Institutions holding TYRA in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.7,236,454$99.6M1.96%00.0%Unchanged
Boxer Capital, LLC6,448,359$88.8M4.73%00.0%Unchanged
Canaan Partners XI LLC4,409,991$60.7M53.26%00.0%Unchanged
FMR LLC3,898,827$53.7M0.00%−218,042−5.3%Reduced
BVF Inc2,739,595$37.7M1.02%00.0%Unchanged
Nextech Invest AG2,518,582$34.7M10.51%00.0%Unchanged
TCG Crossover Management, LLC1,989,103$27.4M4.03%00.0%Unchanged
Fairmount Funds Management LLC1,393,329$19.2M2.31%−23,669−1.7%Reduced
Frazier Life Sciences Management, L.P.1,028,013$14.2M0.94%00.0%Unchanged
BlackRock Inc.896,452$12.3M0.00%+5,620+0.6%Added
Vanguard Group Inc732,584$10.1M0.00%+83,709+12.9%Added
5AM Venture Management, LLC411,450$5.67M1.63%+411,450New
Woodline Partners LP410,435$5.65M0.07%00.0%Unchanged
JPMorgan Chase & Co397,618$5.48M0.00%−25,803−6.1%Reduced
Perceptive Advisors LLC360,000$4.96M0.17%00.0%Unchanged
Geode Capital Management, LLC314,478$4.33M0.00%+24,480+8.4%Added
State Street Corp259,458$3.57M0.00%+3,081+1.2%Added
Driehaus Capital Management LLC150,468$2.07M0.03%00.0%Unchanged
Northern Trust Corp141,599$1.95M0.00%+1,431+1.0%Added
Charles Schwab Investment Management Inc110,214$1.52M0.00%+5,557+5.3%Added
Wellington Management Group LLP94,112$1.30M0.00%+14,676+18.5%Added
Auour Investments LLC85,020$1.20M0.51%00.0%Unchanged
Ikarian Capital, LLC48,170$663.3K0.25%00.0%Unchanged
Artia Global Partners LP45,253$623.1K0.26%00.0%Unchanged
Bank of New York Mellon Corp41,870$576.5K0.00%+1,074+2.6%Added
Victory Capital Management Inc32,730$450.7K0.00%−360−1.1%Reduced
Logos Global Management LP31,872$438.9K0.06%00.0%Unchanged
Mariner, LLC24,296$334.6K0.00%+2,723+12.6%Added
Bank of America Corp22,164$305.2K0.00%+1,752+8.6%Added
Rhumbline Advisers21,461$295.5K0.00%+176+0.8%Added
Nuveen Asset Management, LLC18,756$258.3K0.00%00.0%Unchanged
Morgan Stanley18,284$251.8K0.00%−486−2.6%Reduced
Parkwood LLC16,967$234.0K0.04%+16,967New
LPL Financial LLC14,500$199.7K0.00%−5,000−25.6%Reduced
Susquehanna International Group, LLP11,872$163.5K0.00%+11,872New
Corton Capital Inc.11,009$151.6K0.08%+11,009New
Sepio Capital, LP10,625$146.3K0.01%00.0%Unchanged
Dimensional Fund Advisors LP10,609$146.1K0.00%+8+0.1%Added
MetLife Investment Management7,702$106.1K0.00%00.0%Unchanged
Exchange Traded Concepts, LLC7,114$98.0K0.00%−1,753−19.8%Reduced
American International Group, Inc.6,980$96.1K0.00%+249+3.7%Added
Deutsche Bank AG6,223$85.7K0.00%00.0%Unchanged
UBS Group AG5,310$73.1K0.00%−2,687−33.6%Reduced
New York State Common Retirement Fund4,046$55.7K0.00%+47+1.2%Added
Wells Fargo & Company3,230$44.5K0.00%−2,282−41.4%Reduced
California State Teachers Retirement System3,086$42.5K0.00%−1,566−33.7%Reduced
Barclays PLC2,506$34.5K0.00%−282−10.1%Reduced
Royal Bank of Canada2,134$29.0K0.00%−143−6.3%Reduced
Simplex Trading, LLC2,009$27.0K0.00%+1,335+198.1%Added
Amalgamated Bank1,571$22.0K0.00%00.0%Unchanged
Legal & General Group Plc1,265$17.6K0.00%−267−17.4%Reduced
Ameritas Investment Partners, Inc.940$12.9K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)858$11.8K0.00%+200+30.4%Added
Metropolitan Life Insurance Co814$11.2K0.00%00.0%Unchanged
Federated Hermes, Inc.154$2.12K0.00%−2,911−95.0%Reduced
The PNC Financial Services Group, Inc.58$7990.00%00.0%Unchanged
Citigroup Inc19$2620.00%−4,146−99.5%Reduced
Russell Investments Group, Ltd.19$2620.00%−157−89.2%Reduced
Nisa Investment Advisors, LLC16$2200.00%00.0%Unchanged
Fishman Jay A Ltd0$00.00%−22,000−100.0%Sold out
Millennium Management LLC0$00.00%−21,591−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−10,174−100.0%Sold out
Allspring Global Investments Holdings, LLC0$00.00%−2,273−100.0%Sold out