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Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

13F holders, Q2 2023

Institutional positions in Tyra Biosciences, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
59
+8 vs. Q1 2023
Shares held
36.2M
+556.5K (+1.6%) vs. Q1 2023
Total value
$616.7M
+$43.7M (+7.6%) vs. Q1 2023
New holders
8
20 more added
Sold out
0
13 more reduced

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 59 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 26 institutionsQ4 2021: 45 institutionsQ1 2022: 46 institutionsQ2 2022: 48 institutionsQ3 2022: 49 institutionsQ4 2022: 46 institutionsQ1 2023: 51 institutionsQ2 2023: 59 institutionsQ3 2023: 59 institutionsQ4 2023: 62 institutionsQ1 2024: 77 institutionsQ2 2024: 79 institutionsQ3 2024: 95 institutionsQ4 2024: 113 institutionsQ1 2025: 117 institutionsQ2 2025: 121 institutionsQ3 2025: 116 institutionsQ4 2025: 133 institutionsQ1 2026: 164 institutionsQ2 2026: 168 institutions
Value heldQ2 2023: $616.7M
Q1 2021: $0Q2 2021: $0Q3 2021: $456.8MQ4 2021: $494.2MQ1 2022: $386.6MQ2 2022: $255.6MQ3 2022: $313.8MQ4 2022: $267.8MQ1 2023: $573.0MQ2 2023: $616.7MQ3 2023: $502.1MQ4 2023: $495.2MQ1 2024: $768.4MQ2 2024: $748.6MQ3 2024: $1.11BQ4 2024: $675.8MQ1 2025: $499.5MQ2 2025: $541.5MQ3 2025: $778.4MQ4 2025: $1.49BQ1 2026: $2.52BQ2 2026: $2.22B
Institutions holding TYRA and their total value by quarter
QuarterHoldersValue
Q2 2026168$2.22B
Q1 2026164$2.52B
Q4 2025133$1.49B
Q3 2025116$778.4M
Q2 2025121$541.5M
Q1 2025117$499.5M
Q4 2024113$675.8M
Q3 202495$1.11B
Q2 202479$748.6M
Q1 202477$768.4M
Q4 202362$495.2M
Q3 202359$502.1M
Q2 202359$616.7M
Q1 202351$573.0M
Q4 202246$267.8M
Q3 202249$313.8M
Q2 202248$255.6M
Q1 202246$386.6M
Q4 202145$494.2M
Q3 202126$456.8M
Q2 20210$0
Q1 20210$0

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q1 2023.

Institutions holding TYRA in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.7,236,454$123.2M2.33%00.0%Unchanged
Boxer Capital, LLC6,448,359$109.8M5.09%00.0%Unchanged
Canaan Partners XI LLC4,409,991$75.1M53.19%00.0%Unchanged
FMR LLC4,116,869$70.1M0.01%+968,882+30.8%Added
BVF Inc2,739,595$46.7M1.30%−500,000−15.4%Reduced
Nextech Invest AG2,518,582$42.9M14.58%00.0%Unchanged
TCG Crossover Management, LLC1,989,103$33.9M5.56%00.0%Unchanged
Fairmount Funds Management LLC1,416,998$24.1M3.40%00.0%Unchanged
Frazier Life Sciences Management, L.P.1,028,013$17.5M1.05%−393,297−27.7%Reduced
BlackRock Inc.890,832$15.2M0.00%+223,947+33.6%Added
Vanguard Group Inc648,875$11.1M0.00%+9,551+1.5%Added
JPMorgan Chase & Co423,421$7.21M0.00%+230,912+119.9%Added
Woodline Partners LP410,435$6.99M0.08%00.0%Unchanged
Perceptive Advisors LLC360,000$6.13M0.18%−134,403−27.2%Reduced
Geode Capital Management, LLC289,998$4.94M0.00%+3,894+1.4%Added
State Street Corp256,377$4.37M0.00%+24,288+10.5%Added
Driehaus Capital Management LLC150,468$2.56M0.03%+16,295+12.1%Added
Northern Trust Corp140,168$2.39M0.00%+32,626+30.3%Added
Charles Schwab Investment Management Inc104,657$1.78M0.00%+2,287+2.2%Added
Auour Investments LLC85,020$1.45M0.61%+85,020New
Wellington Management Group LLP79,436$1.35M0.00%−4,824−5.7%Reduced
Ikarian Capital, LLC48,170$820.3K0.29%00.0%Unchanged
Artia Global Partners LP45,253$770.7K0.27%00.0%Unchanged
Bank of New York Mellon Corp40,796$694.8K0.00%−735−1.8%Reduced
Victory Capital Management Inc33,090$563.5K0.00%−670−2.0%Reduced
Logos Global Management LP31,872$542.8K0.07%−55,801−63.6%Reduced
Fishman Jay A Ltd22,000$374.7K0.05%00.0%Unchanged
Millennium Management LLC21,591$367.7K0.00%+8,116+60.2%Added
Mariner, LLC21,573$367.4K0.00%+44+0.2%Added
Rhumbline Advisers21,285$362.5K0.00%−641−2.9%Reduced
Bank of America Corp20,412$347.6K0.00%+2,401+13.3%Added
LPL Financial LLC19,500$332.1K0.00%00.0%Unchanged
Morgan Stanley18,770$319.7K0.00%+3,461+22.6%Added
Nuveen Asset Management, LLC18,756$319.4K0.00%00.0%Unchanged
Sepio Capital, LP10,625$180.9K0.01%00.0%Unchanged
Dimensional Fund Advisors LP10,601$180.5K0.00%+10,601New
Boothbay Fund Management, LLC10,174$173.3K0.01%+10,174New
Exchange Traded Concepts, LLC8,867$151.0K0.00%+8,867New
UBS Group AG7,997$136.2K0.00%+3,378+73.1%Added
MetLife Investment Management7,702$131.2K0.00%00.0%Unchanged
American International Group, Inc.6,731$114.6K0.00%+331+5.2%Added
Deutsche Bank AG6,223$106.0K0.00%−1,915−23.5%Reduced
Wells Fargo & Company5,512$93.9K0.00%+3,150+133.4%Added
California State Teachers Retirement System4,652$79.2K0.00%−278−5.6%Reduced
Citigroup Inc4,165$70.9K0.00%+4,165New
New York State Common Retirement Fund3,999$68.1K0.00%−6,526−62.0%Reduced
Federated Hermes, Inc.3,065$52.2K0.00%+3,011+5,575.9%Added
Barclays PLC2,788$47.5K0.00%−3,997−58.9%Reduced
Royal Bank of Canada2,277$39.0K0.00%+1,535+206.9%Added
Allspring Global Investments Holdings, LLC2,273$38.7K0.00%+2,273New
Amalgamated Bank1,571$27.0K0.00%+246+18.6%Added
Legal & General Group Plc1,532$26.1K0.00%+127+9.0%Added
Ameritas Investment Partners, Inc.940$16.0K0.00%00.0%Unchanged
Metropolitan Life Insurance Co814$13.9K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)658$11.2K0.00%−888−57.4%Reduced
Simplex Trading, LLC674$11.0K0.00%+674New
Russell Investments Group, Ltd.176$3.00K0.00%+176New
The PNC Financial Services Group, Inc.58$9880.00%00.0%Unchanged
Nisa Investment Advisors, LLC16$2720.00%00.0%Unchanged