Skip to main content
Livermore
Livermore
ZHEN

Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

Holders of 5% or more of TYRA

Holders whose latest Schedule 13D or 13G filing reports 5% or more of Tyra Biosciences, Inc., largest stake first. The change is against the holder's previous filing.

Holders of 5% or more of TYRA
HolderLatest formStakeChangeFirst filedLatest filingFiling
Ra Capital Management, L.P.13D/A21.20%12.3M shares−1.20 ppfrom 22.40%Mar 31, 20253 filingsMar 6, 2026SEC
Commodore Capital LP13G/A6.30%3.38M shares+1.10 ppfrom 5.20%May 14, 20252 filingsNov 14, 2025SEC
TCG Crossover GP I, LLC13G5.70%2.90M sharesNewMar 6, 20251 filingMar 6, 2025SEC
Farallon Capital Partners, L.P.13G5.60%2.98M sharesNewFeb 20, 20261 filingFeb 20, 2026SEC
Canaan XI L.P.13G/A5.50%2.93M shares−1.90 ppfrom 7.40%Jan 21, 20252 filingsFeb 13, 2026SEC
Janus Henderson Group PLC13G/A5.40%2.86M shares+0.30 ppfrom 5.10%May 14, 20252 filingsAug 14, 2025SEC
Harris Todd13G5.10%2.81M sharesNewFeb 13, 20261 filingFeb 13, 2026SEC

Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.

13D and 13G filings

17 Schedule 13D and 13G filings on Tyra Biosciences, Inc., newest first, including old-format filings without a stake.

Schedule 13D and 13G filings on TYRA
Filed (ET)FilerFormStakeChangeEvent dateFiling
Mar 6, 20264:28 PM ETRa Capital Management, L.P.and 3 others13D/A21.20%12.3M shares−1.20 ppfrom 22.40%Mar 4, 2026SEC
Feb 20, 20268:14 AM ETFarallon Capital Partners, L.P.and 25 others13G5.60%2.98M sharesNewFeb 12, 2026SEC
Feb 17, 20264:28 PM ETBiotechnology Value Fund L Pand 9 others13G/A4.00%2.13M shares−3.80 ppfrom 7.80%Below 5%Dec 31, 2025SEC
Feb 13, 20264:30 PM ETHarris Todd13G5.10%2.81M sharesNewDec 31, 2025SEC
Feb 13, 20264:15 PM ETCanaan XI L.P.and 3 others13G/A5.50%2.93M shares−1.90 ppfrom 7.40%Dec 31, 2025SEC
Nov 14, 20254:35 PM ETCommodore Capital LPand 3 others13G/A6.30%3.38M shares+1.10 ppfrom 5.20%Sep 30, 2025SEC
Nov 14, 20254:02 PM ETVestal Point Capital, LPand 1 other13G/A4.50%2.42M shares−0.90 ppfrom 5.40%Below 5%Sep 30, 2025SEC
Aug 14, 202511:44 AM ETJanus Henderson Group PLC13G/A5.40%2.86M shares+0.30 ppfrom 5.10%Jun 30, 2025SEC
Jun 6, 20254:50 PM ETRa Capital Management, L.P.and 3 others13D/A22.40%11.9M shares+2.30 ppfrom 20.10%Jun 4, 2025SEC
May 15, 20254:14 PM ETVestal Point Capital, LPand 1 other13G5.40%2.88M sharesNewMar 31, 2025SEC
May 14, 20254:05 PM ETCommodore Capital LPand 1 other13G5.20%2.75M sharesNewMay 7, 2025SEC
May 14, 202511:47 AM ETJanus Henderson Group PLC13G5.10%2.69M sharesNewMar 31, 2025SEC
May 12, 202510:43 AM ETFMR LLCand 1 other13G/A3.20%1.71M shares–Below 5%Mar 31, 2025SEC
Mar 31, 20254:54 PM ETRa Capital Management, L.P.and 3 others13D/A20.10%10.7M shares–Mar 27, 2025SEC
Mar 6, 20256:02 PM ETTCG Crossover GP I, LLCand 2 others13G5.70%2.90M sharesNewFeb 27, 2025SEC
Feb 14, 20254:24 PM ETBiotechnology Value Fund L Pand 9 others13G/A7.80%3.94M shares–Dec 31, 2024SEC
Jan 21, 20254:30 PM ETCanaan XI L.P.and 3 others13G/A7.40%3.73M shares–Dec 31, 2024SEC

Form 144: proposed insider sales

Notices from officers, directors and other affiliates planning to sell Tyra Biosciences, Inc. shares.

No Form 144 notices for Tyra Biosciences, Inc. are on file.