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Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

13F holders, Q3 2022

Institutional positions in Tyra Biosciences, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
49
+1 vs. Q2 2022
Shares held
35.7M
−51.1K (−0.1%) vs. Q2 2022
Total value
$313.8M
+$58.2M (+22.8%) vs. Q2 2022
New holders
4
16 more added
Sold out
3
16 more reduced

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 49 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 26 institutionsQ4 2021: 45 institutionsQ1 2022: 46 institutionsQ2 2022: 48 institutionsQ3 2022: 49 institutionsQ4 2022: 46 institutionsQ1 2023: 51 institutionsQ2 2023: 59 institutionsQ3 2023: 59 institutionsQ4 2023: 62 institutionsQ1 2024: 77 institutionsQ2 2024: 79 institutionsQ3 2024: 95 institutionsQ4 2024: 113 institutionsQ1 2025: 117 institutionsQ2 2025: 121 institutionsQ3 2025: 116 institutionsQ4 2025: 133 institutionsQ1 2026: 164 institutionsQ2 2026: 168 institutions
Value heldQ3 2022: $313.8M
Q1 2021: $0Q2 2021: $0Q3 2021: $456.8MQ4 2021: $494.2MQ1 2022: $386.6MQ2 2022: $255.6MQ3 2022: $313.8MQ4 2022: $267.8MQ1 2023: $573.0MQ2 2023: $616.7MQ3 2023: $502.1MQ4 2023: $495.2MQ1 2024: $768.4MQ2 2024: $748.6MQ3 2024: $1.11BQ4 2024: $675.8MQ1 2025: $499.5MQ2 2025: $541.5MQ3 2025: $778.4MQ4 2025: $1.49BQ1 2026: $2.52BQ2 2026: $2.22B
Institutions holding TYRA and their total value by quarter
QuarterHoldersValue
Q2 2026168$2.22B
Q1 2026164$2.52B
Q4 2025133$1.49B
Q3 2025116$778.4M
Q2 2025121$541.5M
Q1 2025117$499.5M
Q4 2024113$675.8M
Q3 202495$1.11B
Q2 202479$748.6M
Q1 202477$768.4M
Q4 202362$495.2M
Q3 202359$502.1M
Q2 202359$616.7M
Q1 202351$573.0M
Q4 202246$267.8M
Q3 202249$313.8M
Q2 202248$255.6M
Q1 202246$386.6M
Q4 202145$494.2M
Q3 202126$456.8M
Q2 20210$0
Q1 20210$0

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q2 2022.

Institutions holding TYRA in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.7,236,454$63.6M1.36%00.0%Unchanged
Boxer Capital, LLC6,448,359$56.7M3.19%00.0%Unchanged
Canaan Partners XI LLC4,409,991$38.8M15.63%00.0%Unchanged
FMR LLC4,026,301$35.4M0.00%+58,211+1.5%Added
Nextech Invest AG2,518,582$22.1M7.15%00.0%Unchanged
BVF Inc2,472,327$21.7M0.90%00.0%Unchanged
Fairmount Funds Management LLC1,416,998$12.5M2.30%00.0%Unchanged
Frazier Life Sciences Management, L.P.1,327,665$11.7M0.90%−47,400−3.4%Reduced
TCG Crossover Management, LLC945,707$8.31M2.49%+49,289+5.5%Added
Cormorant Asset Management, LP743,988$6.54M0.46%00.0%Unchanged
Janus Henderson Group PLC682,018$6.01M0.00%−30,281−4.3%Reduced
BlackRock Inc.622,098$5.47M0.00%−8,757−1.4%Reduced
Vanguard Group Inc599,953$5.27M0.00%+8,844+1.5%Added
Perceptive Advisors LLC494,403$4.35M0.13%00.0%Unchanged
Geode Capital Management, LLC247,450$2.17M0.00%+22,039+9.8%Added
Woodline Partners LP241,099$2.12M0.03%−48,073−16.6%Reduced
JPMorgan Chase & Co219,547$1.93M0.00%−4,945−2.2%Reduced
State Street Corp217,988$1.92M0.00%+3,963+1.9%Added
Sio Capital Management, LLC152,159$1.34M0.57%00.0%Unchanged
Logos Global Management LP127,316$1.12M0.14%−39,210−23.5%Reduced
Northern Trust Corp103,808$912.0K0.00%+674+0.7%Added
Charles Schwab Investment Management Inc96,175$846.0K0.00%+14,874+18.3%Added
Wellington Management Group LLP85,182$748.0K0.00%+30,318+55.3%Added
Citadel Advisors LLC40,619$357.0K0.00%−34,226−45.7%Reduced
Bank of New York Mellon Corp39,250$345.0K0.00%+7,339+23.0%Added
D. E. Shaw & Co., Inc.34,886$307.0K0.00%−21,168−37.8%Reduced
Rhumbline Advisers20,633$181.0K0.00%+3,348+19.4%Added
LPL Financial LLC20,000$176.0K0.00%−500−2.4%Reduced
Nuveen Asset Management, LLC18,756$165.0K0.00%00.0%Unchanged
Bank of America Corp13,791$121.0K0.00%−5,928−30.1%Reduced
Morgan Stanley12,522$110.0K0.00%−914−6.8%Reduced
New York State Common Retirement Fund10,525$93.0K0.00%+37+0.4%Added
Sepio Capital, LP10,625$93.0K0.01%+10,625New
Fishman Jay A Ltd10,500$92.3K0.01%+10,500New
American International Group, Inc.6,231$55.0K0.00%+89+1.4%Added
California State Teachers Retirement System5,180$46.0K0.00%−432−7.7%Reduced
Deutsche Bank AG4,922$43.0K0.00%−875−15.1%Reduced
Tower Research Capital LLC (TRC)4,203$37.0K0.00%+1,266+43.1%Added
Amalgamated Bank1,621$14.0K0.00%00.0%Unchanged
Legal & General Group Plc1,405$12.0K0.00%+444+46.2%Added
Ameritas Investment Partners, Inc.940$8.00K0.00%00.0%Unchanged
Barclays PLC556$5.00K0.00%−102−15.5%Reduced
Citigroup Inc200$2.00K0.00%−734−78.6%Reduced
Royal Bank of Canada160$1.00K0.00%+86+116.2%Added
The PNC Financial Services Group, Inc.58$1.00K0.00%00.0%Unchanged
Credit Suisse AG73$1.00K0.00%+39+114.7%Added
UBS Group AG91$1.00K0.00%+91New
Wells Fargo & Company39$00.00%−114−74.5%Reduced
Ellevest, Inc.27$00.00%+27New
Susquehanna International Group, LLP0$00.00%−16,663−100.0%Sold out
Bailard, Inc.0$00.00%−12,910−100.0%Sold out
Advisor Group Holdings, Inc.0$00.00%−1−100.0%Sold out