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Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Tyra Biosciences, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
79
+2 vs. Q1 2024
Shares held
46.8M
−37.3K (−0.1%) vs. Q1 2024
Total value
$748.6M
−$19.8M (−2.6%) vs. Q1 2024
New holders
18
31 more added
Sold out
16
16 more reduced

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 79 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 26 institutionsQ4 2021: 45 institutionsQ1 2022: 46 institutionsQ2 2022: 48 institutionsQ3 2022: 49 institutionsQ4 2022: 46 institutionsQ1 2023: 51 institutionsQ2 2023: 59 institutionsQ3 2023: 59 institutionsQ4 2023: 62 institutionsQ1 2024: 77 institutionsQ2 2024: 79 institutionsQ3 2024: 95 institutionsQ4 2024: 113 institutionsQ1 2025: 117 institutionsQ2 2025: 121 institutionsQ3 2025: 116 institutionsQ4 2025: 133 institutionsQ1 2026: 164 institutionsQ2 2026: 168 institutions
Value heldQ2 2024: $748.6M
Q1 2021: $0Q2 2021: $0Q3 2021: $456.8MQ4 2021: $494.2MQ1 2022: $386.6MQ2 2022: $255.6MQ3 2022: $313.8MQ4 2022: $267.8MQ1 2023: $573.0MQ2 2023: $616.7MQ3 2023: $502.1MQ4 2023: $495.2MQ1 2024: $768.4MQ2 2024: $748.6MQ3 2024: $1.11BQ4 2024: $675.8MQ1 2025: $499.5MQ2 2025: $541.5MQ3 2025: $778.4MQ4 2025: $1.49BQ1 2026: $2.52BQ2 2026: $2.22B
Institutions holding TYRA and their total value by quarter
QuarterHoldersValue
Q2 2026168$2.22B
Q1 2026164$2.52B
Q4 2025133$1.49B
Q3 2025116$778.4M
Q2 2025121$541.5M
Q1 2025117$499.5M
Q4 2024113$675.8M
Q3 202495$1.11B
Q2 202479$748.6M
Q1 202477$768.4M
Q4 202362$495.2M
Q3 202359$502.1M
Q2 202359$616.7M
Q1 202351$573.0M
Q4 202246$267.8M
Q3 202249$313.8M
Q2 202248$255.6M
Q1 202246$386.6M
Q4 202145$494.2M
Q3 202126$456.8M
Q2 20210$0
Q1 20210$0

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q1 2024.

Institutions holding TYRA in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.10,416,609$166.6M2.20%00.0%Unchanged
Boxer Capital, LLC6,448,359$103.1M5.43%00.0%Unchanged
BVF Inc4,661,194$74.5M2.09%00.0%Unchanged
Canaan Partners XI LLC4,409,991$70.5M85.38%00.0%Unchanged
Nextech Invest AG4,055,861$64.9M10.91%00.0%Unchanged
FMR LLC3,346,663$53.5M0.00%−630,545−15.9%Reduced
TCG Crossover Management, LLC1,989,103$31.8M3.31%00.0%Unchanged
BlackRock Inc.1,418,855$22.7M0.00%+374,630+35.9%Added
Vanguard Group Inc1,238,501$19.8M0.00%+338,701+37.6%Added
Perceptive Advisors LLC1,007,367$16.1M0.39%+338,208+50.5%Added
5AM Venture Management, LLC939,298$15.0M3.36%00.0%Unchanged
Frazier Life Sciences Management, L.P.832,220$13.3M0.62%00.0%Unchanged
OrbiMed Advisors LLC768,638$12.3M0.26%00.0%Unchanged
Sio Capital Management, LLC600,294$9.60M3.62%+64,553+12.0%Added
Kynam Capital Management, LP566,715$9.06M0.95%+51,525+10.0%Added
Geode Capital Management, LLC522,674$8.36M0.00%+105,866+25.4%Added
Avidity Partners Management LP373,000$5.96M0.25%+373,000New
State Street Corp368,484$5.89M0.00%+76,250+26.1%Added
JPMorgan Chase & Co364,751$5.83M0.00%−15,846−4.2%Reduced
Ally Bridge Group (NY) LLC264,660$4.23M2.52%+264,660New
Ensign Peak Advisors, Inc190,557$3.05M0.01%+190,557New
ExodusPoint Capital Management, LP170,717$2.73M0.03%−101,433−37.3%Reduced
American Century Companies Inc170,283$2.72M0.00%+145,346+582.9%Added
Charles Schwab Investment Management Inc169,945$2.72M0.00%+17,733+11.7%Added
Northern Trust Corp155,451$2.49M0.00%−1,021−0.7%Reduced
Jennison Associates LLC149,350$2.39M0.00%+149,350New
Wellington Management Group LLP117,032$1.87M0.00%+15,244+15.0%Added
Goldman Sachs Group Inc114,874$1.84M0.00%+100,797+716.0%Added
Nuveen Asset Management, LLC92,658$1.48M0.00%+66,945+260.4%Added
Woodline Partners LP88,656$1.42M0.01%+88,656New
Auour Investments LLC85,020$1.36M0.51%00.0%Unchanged
Oppenheimer & Co Inc70,488$1.13M0.02%+10,912+18.3%Added
Morgan Stanley64,531$1.03M0.00%+29,294+83.1%Added
Bank of New York Mellon Corp58,087$928.8K0.00%+14,352+32.8%Added
Bank of America Corp49,517$791.8K0.00%+16,485+49.9%Added
Victory Capital Management Inc47,160$754.1K0.00%−930−1.9%Reduced
Tang Capital Management LLC42,223$675.1K0.07%+42,223New
Jane Street Group, LLC40,998$655.6K0.00%+40,998New
State of Wisconsin Investment Board38,065$608.7K0.00%+38,065New
Two Sigma Investments, LP35,272$564.0K0.00%−6,470−15.5%Reduced
Walleye Capital LLC31,146$498.0K0.01%+14,259+84.4%Added
Rhumbline Advisers23,572$376.9K0.00%+2,574+12.3%Added
Alliancebernstein L.P.17,570$280.9K0.00%+17,570New
HighVista Strategies LLC16,078$257.1K0.09%+16,078New
PDT Partners, LLC15,306$244.7K0.02%+3,132+25.7%Added
Parkwood LLC14,056$225.0K0.03%+14,056New
Jump Financial, LLC12,754$203.9K0.00%−2,405−15.9%Reduced
Barclays PLC12,519$200.2K0.00%+2,669+27.1%Added
Fishman Jay A Ltd12,500$199.9K0.02%−2,500−16.7%Reduced
Exchange Traded Concepts, LLC12,245$195.8K0.00%−3,808−23.7%Reduced
MetLife Investment Management12,207$195.2K0.00%+4,505+58.5%Added
Corebridge Financial, Inc.10,931$174.8K0.00%+10,931New
Mariner, LLC10,785$172.5K0.00%+10,785New
Baker Bros. Advisors LP10,607$169.6K0.00%00.0%Unchanged
Deutsche Bank AG9,327$149.1K0.00%+3,314+55.1%Added
UBS Group AG7,575$121.1K0.00%−6,597−46.5%Reduced
New York State Common Retirement Fund7,423$118.7K0.00%−24,726−76.9%Reduced
Mirae Asset Global ETFs Holdings Ltd.6,508$104.1K0.00%+6,508New
Wells Fargo & Company6,506$104.0K0.00%+1,781+37.7%Added
Virtus ETF Advisers LLC4,560$72.9K0.04%+4,560New
Citigroup Inc4,433$70.9K0.00%−2,673−37.6%Reduced
Legal & General Group Plc2,249$36.0K0.00%+984+77.8%Added
Tower Research Capital LLC (TRC)2,177$34.8K0.00%+2,033+1,411.8%Added
Ameritas Investment Partners, Inc.1,991$31.8K0.00%+1,051+111.8%Added
Royal Bank of Canada1,917$31.0K0.00%+1,597+499.1%Added
California State Teachers Retirement System1,472$23.5K0.00%+66+4.7%Added
STRS Ohio700$11.2K0.00%00.0%Unchanged
Federated Hermes, Inc.566$9.05K0.00%−147−20.6%Reduced
Amalgamated Bank424$7.00K0.00%00.0%Unchanged
ADAR1 Capital Management, LLC300$4.80K0.00%−28,000−98.9%Reduced
The PNC Financial Services Group, Inc.58$9270.00%00.0%Unchanged
Nisa Investment Advisors, LLC40$6400.00%+6+17.6%Added
GAMMA Investing LLC35$5600.00%+19+118.8%Added
Advisor Group Holdings, Inc.34$5440.00%+34New
Russell Investments Group, Ltd.8$1280.00%−118−93.7%Reduced
SRS Capital Advisors, Inc.7$1120.00%+7New
Simplex Trading, LLC59$00.00%−41−41.0%Reduced
CWM, LLC10$00.00%+9+900.0%Added
Covestor Ltd6$00.00%+6New
Fairmount Funds Management LLC0$00.00%−1,393,329−100.0%Sold out
First Turn Management, LLC0$00.00%−381,210−100.0%Sold out
Driehaus Capital Management LLC0$00.00%−203,709−100.0%Sold out
Nicholas Investment Partners, LP0$00.00%−152,968−100.0%Sold out
Renaissance Technologies LLC0$00.00%−54,400−100.0%Sold out
Legato Capital Management LLC0$00.00%−20,259−100.0%Sold out
Marshall Wace, LLP0$00.00%−19,643−100.0%Sold out
Citadel Advisors LLC0$00.00%−16,789−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−13,317−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−10,750−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−7,032−100.0%Sold out
American International Group, Inc.0$00.00%−6,892−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−1,345−100.0%Sold out
Metropolitan Life Insurance Co0$00.00%−814−100.0%Sold out
Ikarian Capital, LLC0$00.00%−501−100.0%Sold out
Nelson, Van Denburg & Campbell Wealth Management Group, LLC0$00.00%−2−100.0%Sold out