Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q1 2022
Institutional positions in Tyra Biosciences, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 46
- +1 vs. Q4 2021
- Shares held
- 36.1M
- +959.6K (+2.7%) vs. Q4 2021
- Total value
- $386.6M
- −$107.5M (−21.8%) vs. Q4 2021
- New holders
- 7
- 12 more added
- Sold out
- 6
- 19 more reduced
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 7,236,454 | $77.4M | 1.69% | 00.0% | Unchanged |
| Boxer Capital, LLC | 6,448,359 | $69.0M | 3.55% | 00.0% | Unchanged |
| Canaan Partners XI LLC | 4,409,991 | $47.2M | 19.65% | 00.0% | Unchanged |
| FMR LLC | 4,090,085 | $43.8M | 0.00% | +621,254+17.9% | Added |
| Nextech Invest AG | 2,518,582 | $26.9M | 7.69% | 00.0% | Unchanged |
| BVF Inc | 2,472,327 | $26.5M | 1.06% | +598,995+32.0% | Added |
| Frazier Life Sciences Management, L.P. | 1,327,665 | $14.2M | 1.21% | +1,327,665 | New |
| Fairmount Funds Management LLC | 1,284,990 | $13.7M | 3.25% | +639,641+99.1% | Added |
| Janus Henderson Group PLC | 909,192 | $9.72M | 0.00% | −257,289−22.1% | Reduced |
| TCG Crossover Management, LLC | 896,418 | $9.59M | 3.85% | +45,968+5.4% | Added |
| Cormorant Asset Management, LP | 757,432 | $8.11M | 0.62% | −82,500−9.8% | Reduced |
| BlackRock Inc. | 583,236 | $6.24M | 0.00% | −5,330−0.9% | Reduced |
| Vanguard Group Inc | 515,637 | $5.52M | 0.00% | −846−0.2% | Reduced |
| Perceptive Advisors LLC | 494,403 | $5.29M | 0.11% | −178,949−26.6% | Reduced |
| Woodline Partners LP | 266,161 | $2.85M | 0.05% | +1,416+0.5% | Added |
| Logos Global Management LP | 252,726 | $2.70M | 0.35% | −220,668−46.6% | Reduced |
| Wellington Management Group LLP | 251,222 | $2.69M | 0.00% | −338,563−57.4% | Reduced |
| JPMorgan Chase & Co | 228,482 | $2.44M | 0.00% | +73,903+47.8% | Added |
| Geode Capital Management, LLC | 210,549 | $2.25M | 0.00% | +4,168+2.0% | Added |
| State Street Corp | 203,680 | $2.18M | 0.00% | +72,670+55.5% | Added |
| Ensign Peak Advisors, Inc | 125,000 | $1.34M | 0.00% | 00.0% | Unchanged |
| Sio Capital Management, LLC | 111,033 | $1.19M | 0.48% | +111,033 | New |
| Northern Trust Corp | 100,104 | $1.07M | 0.00% | −3,389−3.3% | Reduced |
| D. E. Shaw & Co., Inc. | 83,438 | $893.0K | 0.00% | −44,425−34.7% | Reduced |
| Charles Schwab Investment Management Inc | 80,456 | $861.0K | 0.00% | +1,109+1.4% | Added |
| Citadel Advisors LLC | 78,309 | $838.0K | 0.00% | −40.0% | Reduced |
| Bank of America Corp | 64,126 | $686.0K | 0.00% | +58,401+1,020.1% | Added |
| Bank of New York Mellon Corp | 30,620 | $328.0K | 0.00% | +10,045+48.8% | Added |
| Renaissance Technologies LLC | 29,300 | $314.0K | 0.00% | −61,700−67.8% | Reduced |
| Nuveen Asset Management, LLC | 18,400 | $197.0K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 11,726 | $125.0K | 0.00% | +11,726 | New |
| New York State Common Retirement Fund | 10,517 | $113.0K | 0.00% | +10,517 | New |
| Deutsche Bank AG | 6,613 | $71.0K | 0.00% | −776−10.5% | Reduced |
| American International Group, Inc. | 5,856 | $63.0K | 0.00% | −606−9.4% | Reduced |
| California State Teachers Retirement System | 5,064 | $54.0K | 0.00% | −1,601−24.0% | Reduced |
| Wells Fargo & Company | 2,562 | $27.0K | 0.00% | −4,489−63.7% | Reduced |
| Barclays PLC | 1,915 | $20.0K | 0.00% | +1,915 | New |
| UBS Group AG | 1,740 | $19.0K | 0.00% | −3,733−68.2% | Reduced |
| Amalgamated Bank | 1,771 | $19.0K | 0.00% | +1,771 | New |
| Amalgamated Financial Corp. | 1,771 | $19.0K | 0.00% | +1,771 | New |
| Morgan Stanley | 1,571 | $16.0K | 0.00% | −34,177−95.6% | Reduced |
| Tower Research Capital LLC (TRC) | 1,243 | $13.0K | 0.00% | +280+29.1% | Added |
| Legal & General Group Plc | 1,126 | $12.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 940 | $10.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 725 | $8.00K | 0.00% | −1,766−70.9% | Reduced |
| Citigroup Inc | 459 | $5.00K | 0.00% | −2,706−85.5% | Reduced |
| Frazier Management LLC | 0 | $0 | 0.00% | −1,250,000−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −109,523−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −17,999−100.0% | Sold out |
| Old Well Partners, LLC | 0 | $0 | 0.00% | −10,500−100.0% | Sold out |
| STRS Ohio | 0 | $0 | 0.00% | −2,800−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −300−100.0% | Sold out |