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Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Tyra Biosciences, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
46
−3 vs. Q3 2022
Shares held
35.2M
−453.5K (−1.3%) vs. Q3 2022
Total value
$267.8M
−$45.9M (−14.6%) vs. Q3 2022
New holders
1
17 more added
Sold out
4
11 more reduced

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 46 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 26 institutionsQ4 2021: 45 institutionsQ1 2022: 46 institutionsQ2 2022: 48 institutionsQ3 2022: 49 institutionsQ4 2022: 46 institutionsQ1 2023: 51 institutionsQ2 2023: 59 institutionsQ3 2023: 59 institutionsQ4 2023: 62 institutionsQ1 2024: 77 institutionsQ2 2024: 79 institutionsQ3 2024: 95 institutionsQ4 2024: 113 institutionsQ1 2025: 117 institutionsQ2 2025: 121 institutionsQ3 2025: 116 institutionsQ4 2025: 133 institutionsQ1 2026: 164 institutionsQ2 2026: 168 institutions
Value heldQ4 2022: $267.8M
Q1 2021: $0Q2 2021: $0Q3 2021: $456.8MQ4 2021: $494.2MQ1 2022: $386.6MQ2 2022: $255.6MQ3 2022: $313.8MQ4 2022: $267.8MQ1 2023: $573.0MQ2 2023: $616.7MQ3 2023: $502.1MQ4 2023: $495.2MQ1 2024: $768.4MQ2 2024: $748.6MQ3 2024: $1.11BQ4 2024: $675.8MQ1 2025: $499.5MQ2 2025: $541.5MQ3 2025: $778.4MQ4 2025: $1.49BQ1 2026: $2.52BQ2 2026: $2.22B
Institutions holding TYRA and their total value by quarter
QuarterHoldersValue
Q2 2026168$2.22B
Q1 2026164$2.52B
Q4 2025133$1.49B
Q3 2025116$778.4M
Q2 2025121$541.5M
Q1 2025117$499.5M
Q4 2024113$675.8M
Q3 202495$1.11B
Q2 202479$748.6M
Q1 202477$768.4M
Q4 202362$495.2M
Q3 202359$502.1M
Q2 202359$616.7M
Q1 202351$573.0M
Q4 202246$267.8M
Q3 202249$313.8M
Q2 202248$255.6M
Q1 202246$386.6M
Q4 202145$494.2M
Q3 202126$456.8M
Q2 20210$0
Q1 20210$0

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q3 2022.

Institutions holding TYRA in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.7,236,454$55.0M1.12%00.0%Unchanged
Boxer Capital, LLC6,448,359$49.0M2.64%00.0%Unchanged
Canaan Partners XI LLC4,409,991$33.5M26.32%00.0%Unchanged
FMR LLC3,879,123$29.5M0.00%−147,178−3.7%Reduced
Nextech Invest AG2,518,582$19.1M7.61%00.0%Unchanged
BVF Inc2,472,327$18.8M0.79%00.0%Unchanged
TCG Crossover Management, LLC1,989,103$15.1M2.67%+1,043,396+110.3%Added
Fairmount Funds Management LLC1,416,998$10.8M1.71%00.0%Unchanged
Frazier Life Sciences Management, L.P.1,327,665$10.1M0.63%00.0%Unchanged
BlackRock Inc.655,091$4.98M0.00%+32,993+5.3%Added
Vanguard Group Inc604,367$4.59M0.00%+4,414+0.7%Added
Perceptive Advisors LLC494,403$3.76M0.11%00.0%Unchanged
Woodline Partners LP299,016$2.27M0.03%+57,917+24.0%Added
Geode Capital Management, LLC253,692$1.93M0.00%+6,242+2.5%Added
State Street Corp216,626$1.65M0.00%−1,362−0.6%Reduced
JPMorgan Chase & Co199,207$1.51M0.00%−20,340−9.3%Reduced
Sio Capital Management, LLC152,159$1.16M0.62%00.0%Unchanged
Logos Global Management LP110,856$842.5K0.10%−16,460−12.9%Reduced
Northern Trust Corp105,767$803.8K0.00%+1,959+1.9%Added
Charles Schwab Investment Management Inc98,503$748.6K0.00%+2,328+2.4%Added
Wellington Management Group LLP78,155$594.0K0.00%−7,027−8.2%Reduced
Bank of New York Mellon Corp46,369$352.4K0.00%+7,119+18.1%Added
D. E. Shaw & Co., Inc.33,005$250.8K0.00%−1,881−5.4%Reduced
Citadel Advisors LLC26,717$203.0K0.00%−13,902−34.2%Reduced
Fishman Jay A Ltd22,000$167.2K0.02%+11,500+109.5%Added
Bank of America Corp20,962$159.3K0.00%+7,171+52.0%Added
Rhumbline Advisers20,748$158.0K0.00%+115+0.6%Added
LPL Financial LLC20,000$152.0K0.00%00.0%Unchanged
Nuveen Asset Management, LLC18,756$143.0K0.00%00.0%Unchanged
Sepio Capital, LP10,625$80.8K0.01%00.0%Unchanged
New York State Common Retirement Fund10,525$80.0K0.00%00.0%Unchanged
Morgan Stanley10,403$79.1K0.00%−2,119−16.9%Reduced
American International Group, Inc.6,273$47.7K0.00%+42+0.7%Added
California State Teachers Retirement System5,522$42.0K0.00%+342+6.6%Added
Deutsche Bank AG5,011$38.1K0.00%+89+1.8%Added
UBS Group AG3,587$27.3K0.00%+3,496+3,841.8%Added
Barclays PLC3,581$27.2K0.00%+3,025+544.1%Added
Royal Bank of Canada3,344$25.0K0.00%+3,184+1,990.0%Added
Tower Research Capital LLC (TRC)1,893$14.0K0.00%−2,310−55.0%Reduced
Amalgamated Bank1,621$12.0K0.00%00.0%Unchanged
Legal & General Group Plc1,405$10.7K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.940$7.40K0.00%00.0%Unchanged
Citigroup Inc89$6760.00%−111−55.5%Reduced
The PNC Financial Services Group, Inc.58$4410.00%00.0%Unchanged
Credit Suisse AG1$80.00%−72−98.6%Reduced
Nisa Investment Advisors, LLC16$00.00%+16New
Cormorant Asset Management, LP0$00.00%−743,988−100.0%Sold out
Janus Henderson Group PLC0$00.00%−682,018−100.0%Sold out
Wells Fargo & Company0$00.00%−39−100.0%Sold out
Ellevest, Inc.0$00.00%−27−100.0%Sold out