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Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Tyra Biosciences, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
95
+17 vs. Q2 2024
Shares held
47.1M
+1.66M (+3.7%) vs. Q2 2024
Total value
$1.11B
+$380.1M (+52.4%) vs. Q2 2024
New holders
25
29 more added
Sold out
8
20 more reduced

1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 95 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 26 institutionsQ4 2021: 45 institutionsQ1 2022: 46 institutionsQ2 2022: 48 institutionsQ3 2022: 49 institutionsQ4 2022: 46 institutionsQ1 2023: 51 institutionsQ2 2023: 59 institutionsQ3 2023: 59 institutionsQ4 2023: 62 institutionsQ1 2024: 77 institutionsQ2 2024: 79 institutionsQ3 2024: 95 institutionsQ4 2024: 113 institutionsQ1 2025: 117 institutionsQ2 2025: 121 institutionsQ3 2025: 116 institutionsQ4 2025: 133 institutionsQ1 2026: 164 institutionsQ2 2026: 168 institutions
Value heldQ3 2024: $1.11B
Q1 2021: $0Q2 2021: $0Q3 2021: $456.8MQ4 2021: $494.2MQ1 2022: $386.6MQ2 2022: $255.6MQ3 2022: $313.8MQ4 2022: $267.8MQ1 2023: $573.0MQ2 2023: $616.7MQ3 2023: $502.1MQ4 2023: $495.2MQ1 2024: $768.4MQ2 2024: $748.6MQ3 2024: $1.11BQ4 2024: $675.8MQ1 2025: $499.5MQ2 2025: $541.5MQ3 2025: $778.4MQ4 2025: $1.49BQ1 2026: $2.52BQ2 2026: $2.22B
Institutions holding TYRA and their total value by quarter
QuarterHoldersValue
Q2 2026168$2.22B
Q1 2026164$2.52B
Q4 2025133$1.49B
Q3 2025116$778.4M
Q2 2025121$541.5M
Q1 2025117$499.5M
Q4 2024113$675.8M
Q3 202495$1.11B
Q2 202479$748.6M
Q1 202477$768.4M
Q4 202362$495.2M
Q3 202359$502.1M
Q2 202359$616.7M
Q1 202351$573.0M
Q4 202246$267.8M
Q3 202249$313.8M
Q2 202248$255.6M
Q1 202246$386.6M
Q4 202145$494.2M
Q3 202126$456.8M
Q2 20210$0
Q1 20210$0

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q2 2024.

Institutions holding TYRA in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.10,416,609$244.9M2.82%00.0%Unchanged
Boxer Capital, LLC6,448,359$151.6M7.44%00.0%Unchanged
BVF Inc4,661,194$109.6M3.21%00.0%Unchanged
Canaan Partners XI LLC4,409,991$103.7M87.81%00.0%Unchanged
Nextech Invest AG4,055,861$95.4M13.39%00.0%Unchanged
FMR LLC3,372,850$79.3M0.00%+26,187+0.8%Added
TCG Crossover Management, LLC1,989,103$46.8M3.96%00.0%Unchanged
BlackRock, Inc.1,516,172$35.6M0.00%+1,516,172New
Vanguard Group Inc1,245,408$29.3M0.00%+6,907+0.6%Added
Janus Henderson Group PLC1,067,196$25.0M0.01%+1,067,196New
5AM Venture Management, LLC939,298$22.1M4.56%00.0%Unchanged
OrbiMed Advisors LLC768,638$18.1M0.33%00.0%Unchanged
Frazier Life Sciences Management, L.P.731,020$17.2M0.69%−101,200−12.2%Reduced
Geode Capital Management, LLC523,190$12.3M0.00%+516+0.1%Added
Perceptive Advisors LLC511,226$12.0M0.26%−496,141−49.3%Reduced
Kynam Capital Management, LP467,947$11.0M0.85%−98,768−17.4%Reduced
Sio Capital Management, LLC400,870$9.42M4.22%−199,424−33.2%Reduced
State Street Corp384,732$9.05M0.00%+16,248+4.4%Added
JPMorgan Chase & Co368,647$8.67M0.00%+3,896+1.1%Added
Ally Bridge Group (NY) LLC270,075$6.35M3.40%+5,415+2.0%Added
Northern Trust Corp214,353$5.04M0.00%+58,902+37.9%Added
Adage Capital Partners GP, L.L.C.200,000$4.70M0.01%+200,000New
Charles Schwab Investment Management Inc173,737$4.08M0.00%+3,792+2.2%Added
Jennison Associates LLC158,187$3.72M0.00%+8,837+5.9%Added
Tang Capital Management LLC150,000$3.53M0.25%+107,777+255.3%Added
Walleye Capital LLC126,597$2.98M0.03%+95,451+306.5%Added
Ensign Peak Advisors, Inc115,616$2.72M0.00%−74,941−39.3%Reduced
Wellington Management Group LLP90,825$2.14M0.00%−26,207−22.4%Reduced
Goldman Sachs Group Inc89,081$2.09M0.00%−25,793−22.5%Reduced
Polar Asset Management Partners Inc.88,100$2.07M0.05%+88,100New
Oppenheimer & Co Inc76,806$1.81M0.03%+6,318+9.0%Added
Morgan Stanley68,916$1.62M0.00%+4,385+6.8%Added
Woodline Partners LP55,866$1.31M0.01%−32,790−37.0%Reduced
Bank of America Corp54,353$1.28M0.00%+4,836+9.8%Added
Nuveen Asset Management, LLC49,998$1.18M0.00%−42,660−46.0%Reduced
American Century Companies Inc42,999$1.01M0.00%−127,284−74.7%Reduced
Bank of New York Mellon Corp42,786$1.01M0.00%−15,301−26.3%Reduced
Two Sigma Investments, LP39,176$921.0K0.00%+3,904+11.1%Added
Barclays PLC37,625$884.6K0.00%+25,106+200.5%Added
State of Wisconsin Investment Board35,566$836.2K0.00%−2,499−6.6%Reduced
D. E. Shaw & Co., Inc.32,003$752.4K0.00%+32,003New
Jane Street Group, LLC31,003$728.9K0.00%−9,995−24.4%Reduced
Victory Capital Management Inc30,080$707.2K0.00%−17,080−36.2%Reduced
Tudor Investment Corp Et Al26,346$619.4K0.01%+26,346New
Swiss National Bank25,700$604.2K0.00%+25,700New
UBS Asset Management Americas Inc25,209$592.7K0.00%+25,209New
Rhumbline Advisers25,175$591.9K0.00%+1,603+6.8%Added
Citadel Advisors LLC23,952$563.1K0.00%+23,952New
Cinctive Capital Management LP22,900$538.4K0.03%+22,900New
Options Solutions, LLC21,023$494.3K0.24%+21,023New
Quest Partners LLC20,878$490.8K0.04%+20,878New
Marshall Wace, LLP19,614$461.1K0.00%+19,614New
Alliancebernstein L.P.17,570$413.1K0.00%00.0%Unchanged
HighVista Strategies LLC16,078$378.0K0.13%00.0%Unchanged
Auour Investments LLC21,020$355.4K0.13%−64,000−75.3%Reduced
Citigroup Inc14,667$344.8K0.00%+10,234+230.9%Added
Manufacturers Life Insurance Company, The14,184$333.5K0.00%+14,184New
SG Americas Securities, LLC13,211$311.0K0.00%+13,211New
Valence8 US LP13,188$310.1K0.14%+13,188New
Balyasny Asset Management LLC12,988$305.3K0.00%+12,988New
California State Teachers Retirement System12,936$304.1K0.00%+11,464+778.8%Added
Deutsche Bank AG12,443$292.5K0.00%+3,116+33.4%Added
MetLife Investment Management12,207$287.0K0.00%00.0%Unchanged
Franklin Resources Inc12,647$278.5K0.00%+12,647New
Mirae Asset Global ETFs Holdings Ltd.11,109$261.2K0.00%+4,601+70.7%Added
UBS Group AG10,964$257.8K0.00%+3,389+44.7%Added
Corebridge Financial, Inc.10,864$255.4K0.00%−67−0.6%Reduced
Baker Bros. Advisors LP10,607$249.4K0.00%00.0%Unchanged
Millennium Management LLC10,504$246.9K0.00%+10,504New
Dimensional Fund Advisors LP9,907$232.9K0.00%+9,907New
Legal & General Group Plc9,340$219.6K0.00%+7,091+315.3%Added
Mariner, LLC9,269$217.9K0.00%−1,516−14.1%Reduced
Exchange Traded Concepts, LLC8,311$195.4K0.00%−3,934−32.1%Reduced
New York State Common Retirement Fund7,423$174.5K0.00%00.0%Unchanged
Wells Fargo & Company6,257$147.1K0.00%−249−3.8%Reduced
Virtus ETF Advisers LLC4,642$109.1K0.05%+82+1.8%Added
Royal Bank of Canada2,135$50.0K0.00%+218+11.4%Added
Ameritas Investment Partners, Inc.1,991$46.8K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,211$28.5K0.00%−966−44.4%Reduced
Federated Hermes, Inc.930$21.9K0.00%+364+64.3%Added
Acadian Asset Management LLC848$19.0K0.00%+848New
STRS Ohio700$16.5K0.00%00.0%Unchanged
Amalgamated Bank424$10.0K0.00%00.0%Unchanged
nVerses Capital, LLC400$9.40K0.00%+400New
Advisor Group Holdings, Inc.205$4.82K0.00%+171+502.9%Added
GAMMA Investing LLC83$1.95K0.00%+48+137.1%Added
The PNC Financial Services Group, Inc.58$1.36K0.00%00.0%Unchanged
CWM, LLC22$1.00K0.00%+12+120.0%Added
Nisa Investment Advisors, LLC40$9400.00%00.0%Unchanged
Sterling Capital Management LLC21$4940.00%+21New
Rothschild Investment LLC15$3530.00%+15New
Russell Investments Group, Ltd.8$1880.00%00.0%Unchanged
SRS Capital Advisors, Inc.7$1650.00%00.0%Unchanged
Capital Performance Advisors LLP5$1180.00%+5New
Covestor Ltd6$00.00%00.0%Unchanged
Avidity Partners Management LP0$00.00%−373,000−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−170,717−100.0%Sold out
PDT Partners, LLC0$00.00%−15,306−100.0%Sold out
Parkwood LLC0$00.00%−14,056−100.0%Sold out
Jump Financial, LLC0$00.00%−12,754−100.0%Sold out