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Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

13F holders, Q2 2022

Institutional positions in Tyra Biosciences, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
48
+3 vs. Q1 2022
Shares held
35.7M
−387.7K (−1.1%) vs. Q1 2022
Total value
$255.6M
−$131.0M (−33.9%) vs. Q1 2022
New holders
6
18 more added
Sold out
3
16 more reduced

1 institution that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 48 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 26 institutionsQ4 2021: 45 institutionsQ1 2022: 46 institutionsQ2 2022: 48 institutionsQ3 2022: 49 institutionsQ4 2022: 46 institutionsQ1 2023: 51 institutionsQ2 2023: 59 institutionsQ3 2023: 59 institutionsQ4 2023: 62 institutionsQ1 2024: 77 institutionsQ2 2024: 79 institutionsQ3 2024: 95 institutionsQ4 2024: 113 institutionsQ1 2025: 117 institutionsQ2 2025: 121 institutionsQ3 2025: 116 institutionsQ4 2025: 133 institutionsQ1 2026: 164 institutionsQ2 2026: 168 institutions
Value heldQ2 2022: $255.6M
Q1 2021: $0Q2 2021: $0Q3 2021: $456.8MQ4 2021: $503.6MQ1 2022: $386.6MQ2 2022: $255.6MQ3 2022: $319.8MQ4 2022: $267.8MQ1 2023: $623.6MQ2 2023: $616.7MQ3 2023: $502.1MQ4 2023: $501.2MQ1 2024: $775.8MQ2 2024: $754.4MQ3 2024: $1.11BQ4 2024: $675.8MQ1 2025: $499.5MQ2 2025: $541.7MQ3 2025: $779.4MQ4 2025: $1.49BQ1 2026: $2.54BQ2 2026: $2.22B
Institutions holding TYRA and their total value by quarter
QuarterHoldersValue
Q2 2026168$2.22B
Q1 2026164$2.54B
Q4 2025133$1.49B
Q3 2025116$779.4M
Q2 2025121$541.7M
Q1 2025117$499.5M
Q4 2024113$675.8M
Q3 202495$1.11B
Q2 202479$754.4M
Q1 202477$775.8M
Q4 202362$501.2M
Q3 202359$502.1M
Q2 202359$616.7M
Q1 202351$623.6M
Q4 202246$267.8M
Q3 202249$319.8M
Q2 202248$255.6M
Q1 202246$386.6M
Q4 202145$503.6M
Q3 202126$456.8M
Q2 20210$0
Q1 20210$0

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q1 2022.

Institutions holding TYRA in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.7,236,454$51.7M1.38%00.0%Unchanged
Boxer Capital, LLC6,448,359$46.1M2.92%00.0%Unchanged
Canaan Partners XI LLC4,409,991$31.5M11.23%00.0%Unchanged
FMR LLC3,968,090$28.4M0.00%−121,995−3.0%Reduced
Nextech Invest AG2,518,582$18.0M6.07%00.0%Unchanged
BVF Inc2,472,327$17.7M0.85%00.0%Unchanged
Fairmount Funds Management LLC1,416,998$10.1M2.32%+132,008+10.3%Added
Frazier Life Sciences Management, L.P.1,375,065$9.83M0.93%+47,400+3.6%Added
TCG Crossover Management, LLC896,418$6.41M2.72%00.0%Unchanged
Cormorant Asset Management, LP743,988$5.32M0.41%−13,444−1.8%Reduced
Janus Henderson Group PLC712,299$5.09M0.00%−196,893−21.7%Reduced
BlackRock Inc.630,855$4.51M0.00%+47,619+8.2%Added
Vanguard Group Inc591,109$4.23M0.00%+75,472+14.6%Added
Perceptive Advisors LLC494,403$3.54M0.11%00.0%Unchanged
Woodline Partners LP289,172$2.07M0.03%+23,011+8.6%Added
Geode Capital Management, LLC225,411$1.61M0.00%+14,862+7.1%Added
JPMorgan Chase & Co224,492$1.60M0.00%−3,990−1.7%Reduced
State Street Corp214,025$1.53M0.00%+10,345+5.1%Added
Logos Global Management LP166,526$1.19M0.22%−86,200−34.1%Reduced
Sio Capital Management, LLC152,159$1.09M0.43%+41,126+37.0%Added
Northern Trust Corp103,134$738.0K0.00%+3,030+3.0%Added
Charles Schwab Investment Management Inc81,301$582.0K0.00%+845+1.1%Added
Citadel Advisors LLC74,845$535.0K0.00%−3,464−4.4%Reduced
D. E. Shaw & Co., Inc.56,054$401.0K0.00%−27,384−32.8%Reduced
Wellington Management Group LLP54,864$392.0K0.00%−196,358−78.2%Reduced
Bank of New York Mellon Corp31,911$228.0K0.00%+1,291+4.2%Added
LPL Financial LLC20,500$147.0K0.00%+20,500New
Bank of America Corp19,719$141.0K0.00%−44,407−69.2%Reduced
Nuveen Asset Management, LLC18,756$134.0K0.00%+356+1.9%Added
Rhumbline Advisers17,285$124.0K0.00%+5,559+47.4%Added
Susquehanna International Group, LLP16,663$119.0K0.00%+16,663New
Morgan Stanley13,436$96.0K0.00%+11,865+755.3%Added
Bailard, Inc.12,910$92.0K0.00%+12,910New
New York State Common Retirement Fund10,488$75.0K0.00%−29−0.3%Reduced
American International Group, Inc.6,142$44.0K0.00%+286+4.9%Added
Deutsche Bank AG5,797$41.0K0.00%−816−12.3%Reduced
California State Teachers Retirement System5,612$40.0K0.00%+548+10.8%Added
Tower Research Capital LLC (TRC)2,937$21.0K0.00%+1,694+136.3%Added
Amalgamated Bank1,621$12.0K0.00%−150−8.5%Reduced
Legal & General Group Plc961$7.00K0.00%−165−14.7%Reduced
Citigroup Inc934$7.00K0.00%+475+103.5%Added
Ameritas Investment Partners, Inc.940$6.00K0.00%00.0%Unchanged
Barclays PLC658$5.00K0.00%−1,257−65.6%Reduced
Wells Fargo & Company153$1.00K0.00%−2,409−94.0%Reduced
Royal Bank of Canada74$1.00K0.00%−651−89.8%Reduced
The PNC Financial Services Group, Inc.58$00.00%+58New
Credit Suisse AG34$00.00%+34New
Advisor Group Holdings, Inc.1$00.00%+1New
Ensign Peak Advisors, Inc0$00.00%−125,000−100.0%Sold out
Renaissance Technologies LLC0$00.00%−29,300−100.0%Sold out
UBS Group AG0$00.00%−1,740−100.0%Sold out
Amalgamated Financial Corp.––––Not filed