Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q4 2023
Institutional positions in Tyra Biosciences, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 62
- +3 vs. Q3 2023
- Shares held
- 35.8M
- −705.9K (−1.9%) vs. Q3 2023
- Total value
- $495.2M
- −$6.93M (−1.4%) vs. Q3 2023
- New holders
- 9
- 21 more added
- Sold out
- 6
- 12 more reduced
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 7,236,454 | $100.2M | 1.57% | 00.0% | Unchanged |
| Boxer Capital, LLC | 6,448,359 | $89.3M | 4.45% | 00.0% | Unchanged |
| Canaan Partners XI LLC | 4,409,991 | $61.1M | 76.34% | 00.0% | Unchanged |
| FMR LLC | 2,768,696 | $38.3M | 0.00% | −1,130,131−29.0% | Reduced |
| BVF Inc | 2,739,595 | $37.9M | 0.95% | 00.0% | Unchanged |
| Nextech Invest AG | 2,518,582 | $34.9M | 6.50% | 00.0% | Unchanged |
| TCG Crossover Management, LLC | 1,989,103 | $27.5M | 3.06% | 00.0% | Unchanged |
| Fairmount Funds Management LLC | 1,393,329 | $19.3M | 2.04% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 1,026,420 | $14.2M | 0.76% | −1,593−0.2% | Reduced |
| BlackRock Inc. | 965,034 | $13.4M | 0.00% | +68,582+7.7% | Added |
| Vanguard Group Inc | 758,967 | $10.5M | 0.00% | +26,383+3.6% | Added |
| 5AM Venture Management, LLC | 554,979 | $7.69M | 2.04% | +143,529+34.9% | Added |
| JPMorgan Chase & Co | 401,706 | $5.56M | 0.00% | +4,088+1.0% | Added |
| Perceptive Advisors LLC | 360,000 | $4.99M | 0.11% | 00.0% | Unchanged |
| Kynam Capital Management, LP | 340,190 | $4.71M | 0.53% | +340,190 | New |
| Geode Capital Management, LLC | 333,469 | $4.62M | 0.00% | +18,991+6.0% | Added |
| State Street Corp | 265,354 | $3.68M | 0.00% | +5,896+2.3% | Added |
| Driehaus Capital Management LLC | 203,709 | $2.82M | 0.03% | +53,241+35.4% | Added |
| Northern Trust Corp | 152,250 | $2.11M | 0.00% | +10,651+7.5% | Added |
| EcoR1 Capital, LLC | 137,014 | $1.90M | 0.05% | +137,014 | New |
| Charles Schwab Investment Management Inc | 110,537 | $1.53M | 0.00% | +323+0.3% | Added |
| Wellington Management Group LLP | 102,436 | $1.42M | 0.00% | +8,324+8.8% | Added |
| Auour Investments LLC | 85,020 | $1.14M | 0.45% | 00.0% | Unchanged |
| Victory Capital Management Inc | 50,220 | $695.5K | 0.00% | +17,490+53.4% | Added |
| Ikarian Capital, LLC | 48,170 | $667.2K | 0.18% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 41,945 | $580.9K | 0.00% | +75+0.2% | Added |
| Morgan Stanley | 35,668 | $494.0K | 0.00% | +17,384+95.1% | Added |
| Marshall Wace, LLP | 30,001 | $415.5K | 0.00% | +30,001 | New |
| Nuveen Asset Management, LLC | 25,713 | $356.1K | 0.00% | +6,957+37.1% | Added |
| Mariner, LLC | 22,164 | $307.0K | 0.00% | −2,132−8.8% | Reduced |
| Bank of America Corp | 22,118 | $306.3K | 0.00% | −46−0.2% | Reduced |
| Rhumbline Advisers | 21,332 | $295.4K | 0.00% | −129−0.6% | Reduced |
| Barclays PLC | 19,227 | $266.3K | 0.00% | +16,721+667.2% | Added |
| American Century Companies Inc | 10,880 | $150.7K | 0.00% | +10,880 | New |
| Sepio Capital, LP | 10,625 | $147.2K | 0.01% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 10,609 | $146.9K | 0.00% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 10,607 | $146.9K | 0.00% | +10,607 | New |
| LPL Financial LLC | 10,500 | $145.4K | 0.00% | −4,000−27.6% | Reduced |
| Artia Global Partners LP | 10,253 | $142.0K | 0.06% | −35,000−77.3% | Reduced |
| Exchange Traded Concepts, LLC | 9,531 | $132.0K | 0.00% | +2,417+34.0% | Added |
| Acuta Capital Partners, LLC | 8,867 | $122.8K | 0.07% | +8,867 | New |
| MetLife Investment Management | 7,702 | $106.7K | 0.00% | 00.0% | Unchanged |
| American International Group, Inc. | 6,951 | $96.3K | 0.00% | −29−0.4% | Reduced |
| Deutsche Bank AG | 6,223 | $86.2K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 4,977 | $68.9K | 0.00% | −333−6.3% | Reduced |
| AJOVista, LLC | 4,235 | $58.7K | 0.07% | +4,235 | New |
| Royal Bank of Canada | 4,244 | $58.0K | 0.00% | +2,110+98.9% | Added |
| Wells Fargo & Company | 4,073 | $56.4K | 0.00% | +843+26.1% | Added |
| New York State Common Retirement Fund | 4,031 | $55.8K | 0.00% | −15−0.4% | Reduced |
| Qube Research & Technologies Ltd | 2,653 | $36.7K | 0.00% | +2,653 | New |
| California State Teachers Retirement System | 2,302 | $31.9K | 0.00% | −784−25.4% | Reduced |
| Federated Hermes, Inc. | 2,070 | $28.7K | 0.00% | +1,916+1,244.2% | Added |
| Citigroup Inc | 2,031 | $28.1K | 0.00% | +2,012+10,589.5% | Added |
| Amalgamated Bank | 1,445 | $20.0K | 0.00% | −126−8.0% | Reduced |
| Legal & General Group Plc | 1,265 | $17.6K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 1,004 | $13.9K | 0.00% | +146+17.0% | Added |
| Ameritas Investment Partners, Inc. | 940 | $13.0K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 814 | $11.3K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 58 | $803 | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 19 | $263 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 16 | $222 | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 16 | $214 | 0.00% | +16 | New |
| Woodline Partners LP | 0 | $0 | 0.00% | −410,435−100.0% | Sold out |
| Logos Global Management LP | 0 | $0 | 0.00% | −31,872−100.0% | Sold out |
| Parkwood LLC | 0 | $0 | 0.00% | −16,967−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −11,872−100.0% | Sold out |
| Corton Capital Inc. | 0 | $0 | 0.00% | −11,009−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −2,009−100.0% | Sold out |