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Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Tyra Biosciences, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
51
+5 vs. Q4 2022
Shares held
35.7M
+414.5K (+1.2%) vs. Q4 2022
Total value
$573.0M
+$305.1M (+113.9%) vs. Q4 2022
New holders
10
16 more added
Sold out
5
10 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 51 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 26 institutionsQ4 2021: 45 institutionsQ1 2022: 46 institutionsQ2 2022: 48 institutionsQ3 2022: 49 institutionsQ4 2022: 46 institutionsQ1 2023: 51 institutionsQ2 2023: 59 institutionsQ3 2023: 59 institutionsQ4 2023: 62 institutionsQ1 2024: 77 institutionsQ2 2024: 79 institutionsQ3 2024: 95 institutionsQ4 2024: 113 institutionsQ1 2025: 117 institutionsQ2 2025: 121 institutionsQ3 2025: 116 institutionsQ4 2025: 133 institutionsQ1 2026: 164 institutionsQ2 2026: 168 institutions
Value heldQ1 2023: $573.0M
Q1 2021: $0Q2 2021: $0Q3 2021: $456.8MQ4 2021: $494.2MQ1 2022: $386.6MQ2 2022: $255.6MQ3 2022: $313.8MQ4 2022: $267.8MQ1 2023: $573.0MQ2 2023: $616.7MQ3 2023: $502.1MQ4 2023: $495.2MQ1 2024: $768.4MQ2 2024: $748.6MQ3 2024: $1.11BQ4 2024: $675.8MQ1 2025: $499.5MQ2 2025: $541.5MQ3 2025: $778.4MQ4 2025: $1.49BQ1 2026: $2.52BQ2 2026: $2.22B
Institutions holding TYRA and their total value by quarter
QuarterHoldersValue
Q2 2026168$2.22B
Q1 2026164$2.52B
Q4 2025133$1.49B
Q3 2025116$778.4M
Q2 2025121$541.5M
Q1 2025117$499.5M
Q4 2024113$675.8M
Q3 202495$1.11B
Q2 202479$748.6M
Q1 202477$768.4M
Q4 202362$495.2M
Q3 202359$502.1M
Q2 202359$616.7M
Q1 202351$573.0M
Q4 202246$267.8M
Q3 202249$313.8M
Q2 202248$255.6M
Q1 202246$386.6M
Q4 202145$494.2M
Q3 202126$456.8M
Q2 20210$0
Q1 20210$0

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q4 2022.

Institutions holding TYRA in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.7,236,454$116.3M2.63%00.0%Unchanged
Boxer Capital, LLC6,448,359$103.6M5.09%00.0%Unchanged
Canaan Partners XI LLC4,409,991$70.9M50.98%00.0%Unchanged
BVF Inc3,239,595$52.1M1.90%+767,268+31.0%Added
FMR LLC3,147,987$50.6M0.00%−731,136−18.8%Reduced
Nextech Invest AG2,518,582$40.5M16.89%00.0%Unchanged
TCG Crossover Management, LLC1,989,103$32.0M6.23%00.0%Unchanged
Frazier Life Sciences Management, L.P.1,421,310$22.8M1.65%+93,645+7.1%Added
Fairmount Funds Management LLC1,416,998$22.8M3.92%00.0%Unchanged
BlackRock Inc.666,885$10.7M0.00%+11,794+1.8%Added
Vanguard Group Inc639,324$10.3M0.00%+34,957+5.8%Added
Perceptive Advisors LLC494,403$7.95M0.24%00.0%Unchanged
Woodline Partners LP410,435$6.60M0.09%+111,419+37.3%Added
Geode Capital Management, LLC286,104$4.60M0.00%+32,412+12.8%Added
State Street Corp232,089$3.73M0.00%+15,463+7.1%Added
JPMorgan Chase & Co192,509$3.09M0.00%−6,698−3.4%Reduced
Driehaus Capital Management LLC134,173$2.16M0.03%+134,173New
Northern Trust Corp107,542$1.73M0.00%+1,775+1.7%Added
Charles Schwab Investment Management Inc102,370$1.65M0.00%+3,867+3.9%Added
Logos Global Management LP87,673$1.41M0.20%−23,183−20.9%Reduced
Wellington Management Group LLP84,260$1.35M0.00%+6,105+7.8%Added
Ikarian Capital, LLC48,170$774.1K0.32%+48,170New
Artia Global Partners LP45,253$727.2K0.29%+45,253New
Bank of New York Mellon Corp41,531$667.4K0.00%−4,838−10.4%Reduced
Victory Capital Management Inc33,760$542.5K0.00%+33,760New
Fishman Jay A Ltd22,000$353.5K0.05%00.0%Unchanged
Rhumbline Advisers21,926$352.0K0.00%+1,178+5.7%Added
Mariner, LLC21,529$346.0K0.00%+21,529New
LPL Financial LLC19,500$313.4K0.00%−500−2.5%Reduced
Nuveen Asset Management, LLC18,756$301.0K0.00%00.0%Unchanged
Bank of America Corp18,011$289.4K0.00%−2,951−14.1%Reduced
Morgan Stanley15,309$246.0K0.00%+4,906+47.2%Added
Millennium Management LLC13,475$217.0K0.00%+13,475New
Sepio Capital, LP10,625$170.7K0.02%00.0%Unchanged
New York State Common Retirement Fund10,525$169.1K0.00%00.0%Unchanged
Deutsche Bank AG8,138$130.8K0.00%+3,127+62.4%Added
MetLife Investment Management7,702$123.8K0.00%+7,702New
Barclays PLC6,785$109.0K0.00%+3,204+89.5%Added
American International Group, Inc.6,400$102.8K0.00%+127+2.0%Added
California State Teachers Retirement System4,930$79.2K0.00%−592−10.7%Reduced
UBS Group AG4,619$74.2K0.00%+1,032+28.8%Added
Wells Fargo & Company2,362$38.0K0.00%+2,362New
Tower Research Capital LLC (TRC)1,546$25.0K0.00%−347−18.3%Reduced
Legal & General Group Plc1,405$22.6K0.00%00.0%Unchanged
Amalgamated Bank1,325$21.0K0.00%−296−18.3%Reduced
Ameritas Investment Partners, Inc.940$15.1K0.00%00.0%Unchanged
Metropolitan Life Insurance Co814$13.1K0.00%+814New
Royal Bank of Canada742$12.0K0.00%−2,602−77.8%Reduced
The PNC Financial Services Group, Inc.58$9320.00%00.0%Unchanged
Federated Hermes, Inc.54$8680.00%+54New
Nisa Investment Advisors, LLC16$00.00%00.0%Unchanged
Sio Capital Management, LLC0$00.00%−152,159−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−33,005−100.0%Sold out
Citadel Advisors LLC0$00.00%−26,717−100.0%Sold out
Citigroup Inc0$00.00%−89−100.0%Sold out
Credit Suisse AG0$00.00%−1−100.0%Sold out