Skip to main content

Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Tyra Biosciences, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
45
+19 vs. Q3 2021
Shares held
35.2M
+9.09M (+34.9%) vs. Q3 2021
Total value
$494.2M
+$37.4M (+8.2%) vs. Q3 2021
New holders
28
7 more added
Sold out
9
7 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 45 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 26 institutionsQ4 2021: 45 institutionsQ1 2022: 46 institutionsQ2 2022: 48 institutionsQ3 2022: 49 institutionsQ4 2022: 46 institutionsQ1 2023: 51 institutionsQ2 2023: 59 institutionsQ3 2023: 59 institutionsQ4 2023: 62 institutionsQ1 2024: 77 institutionsQ2 2024: 79 institutionsQ3 2024: 95 institutionsQ4 2024: 113 institutionsQ1 2025: 117 institutionsQ2 2025: 121 institutionsQ3 2025: 116 institutionsQ4 2025: 133 institutionsQ1 2026: 164 institutionsQ2 2026: 168 institutions
Value heldQ4 2021: $494.2M
Q1 2021: $0Q2 2021: $0Q3 2021: $456.8MQ4 2021: $494.2MQ1 2022: $386.6MQ2 2022: $255.6MQ3 2022: $313.8MQ4 2022: $267.8MQ1 2023: $573.0MQ2 2023: $616.7MQ3 2023: $502.1MQ4 2023: $495.2MQ1 2024: $768.4MQ2 2024: $748.6MQ3 2024: $1.11BQ4 2024: $675.8MQ1 2025: $499.5MQ2 2025: $541.5MQ3 2025: $778.4MQ4 2025: $1.49BQ1 2026: $2.52BQ2 2026: $2.22B
Institutions holding TYRA and their total value by quarter
QuarterHoldersValue
Q2 2026168$2.22B
Q1 2026164$2.52B
Q4 2025133$1.49B
Q3 2025116$778.4M
Q2 2025121$541.5M
Q1 2025117$499.5M
Q4 2024113$675.8M
Q3 202495$1.11B
Q2 202479$748.6M
Q1 202477$768.4M
Q4 202362$495.2M
Q3 202359$502.1M
Q2 202359$616.7M
Q1 202351$573.0M
Q4 202246$267.8M
Q3 202249$313.8M
Q2 202248$255.6M
Q1 202246$386.6M
Q4 202145$494.2M
Q3 202126$456.8M
Q2 20210$0
Q1 20210$0

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q3 2021.

Institutions holding TYRA in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.7,236,454$101.8M1.80%00.0%Unchanged
Boxer Capital, LLC6,448,359$90.7M3.61%+125,000+2.0%Added
Canaan Partners XI LLC4,409,991$62.0M15.98%+4,409,991New
FMR LLC3,468,831$48.8M0.00%+1,560,172+81.7%Added
Nextech Invest AG2,518,582$35.4M9.34%+2,518,582New
BVF Inc1,873,332$26.4M0.96%+178,399+10.5%Added
Frazier Management LLC1,250,000$17.6M1.35%00.0%Unchanged
Janus Henderson Group PLC1,166,481$15.9M0.01%−208,167−15.1%Reduced
TCG Crossover Management, LLC850,450$12.0M5.60%+850,450New
Cormorant Asset Management, LP839,932$11.6M0.69%−230,000−21.5%Reduced
Perceptive Advisors LLC673,352$9.47M0.15%−314,148−31.8%Reduced
Fairmount Funds Management LLC645,349$9.08M2.99%+146,309+29.3%Added
Wellington Management Group LLP589,785$8.30M0.00%−105,586−15.2%Reduced
BlackRock Inc.588,566$8.28M0.00%+588,566New
Vanguard Group Inc516,483$7.27M0.00%+516,483New
Logos Global Management LP473,394$6.66M0.69%−530,000−52.8%Reduced
Woodline Partners LP264,745$3.73M0.05%−101,290−27.7%Reduced
Geode Capital Management, LLC206,381$2.90M0.00%+206,381New
JPMorgan Chase & Co154,579$2.17M0.00%+154,579New
State Street Corp131,010$1.84M0.00%+131,010New
D. E. Shaw & Co., Inc.127,863$1.80M0.00%+127,863New
Ensign Peak Advisors, Inc125,000$1.76M0.00%00.0%Unchanged
Millennium Management LLC109,523$1.54M0.00%+16,022+17.1%Added
Northern Trust Corp103,493$1.46M0.00%+103,493New
Renaissance Technologies LLC91,000$1.28M0.00%+91,000New
Charles Schwab Investment Management Inc79,347$1.12M0.00%+79,347New
Citadel Advisors LLC78,313$1.10M0.00%+78,313New
Morgan Stanley35,748$503.0K0.00%+35,748New
Bank of New York Mellon Corp20,575$289.0K0.00%+20,575New
Nuveen Asset Management, LLC18,400$259.0K0.00%+18,400New
HRT Financial LP17,999$253.0K0.00%−13,806−43.4%Reduced
Old Well Partners, LLC10,500$148.0K0.09%+10,500New
Deutsche Bank AG7,389$104.0K0.00%+7,389New
Wells Fargo & Company7,051$99.0K0.00%+7,051New
California State Teachers Retirement System6,665$94.0K0.00%+6,665New
American International Group, Inc.6,462$91.0K0.00%+6,462New
Bank of America Corp5,725$80.0K0.00%+4,840+546.9%Added
UBS Group AG5,473$77.0K0.00%+5,473New
Citigroup Inc3,165$45.0K0.00%+2,725+619.3%Added
STRS Ohio2,800$39.0K0.00%+2,800New
Royal Bank of Canada2,491$35.0K0.00%+2,491New
Legal & General Group Plc1,126$16.0K0.00%+1,126New
Tower Research Capital LLC (TRC)963$14.0K0.00%+963New
Ameritas Investment Partners, Inc.940$13.0K0.00%+940New
Northwestern Mutual Wealth Management Co300$4.00K0.00%+300New
Deerfield Management Company, L.P. (Series C)0$00.00%−625,000−100.0%Sold out
Jennison Associates LLC0$00.00%−468,750−100.0%Sold out
Goldman Sachs Group Inc0$00.00%−207,283−100.0%Sold out
LMR Partners LLP0$00.00%−54,000−100.0%Sold out
Pinz Capital Management, LP0$00.00%−27,700−100.0%Sold out
Samson Rock Capital LLP0$00.00%−15,267−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−11,456−100.0%Sold out
Maven Securities LTD0$00.00%−10,140−100.0%Sold out
Red Tortoise LLC0$00.00%−212−100.0%Sold out