Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q1 2024
Institutional positions in Tyra Biosciences, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 77
- +15 vs. Q4 2023
- Shares held
- 46.9M
- +11.1M (+31.0%) vs. Q4 2023
- Total value
- $768.4M
- +$273.2M (+55.2%) vs. Q4 2023
- New holders
- 22
- 25 more added
- Sold out
- 7
- 16 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| CWM, LLC | 1 | $0 | 0.00% | +1 | New |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 2 | $32 | 0.00% | +2 | New |
| GAMMA Investing LLC | 16 | $262 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 34 | $558 | 0.00% | +18+112.5% | Added |
| The PNC Financial Services Group, Inc. | 58 | $951 | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 100 | $1.00K | 0.00% | +100 | New |
| Russell Investments Group, Ltd. | 126 | $2.07K | 0.00% | +107+563.2% | Added |
| Tower Research Capital LLC (TRC) | 144 | $2.36K | 0.00% | −860−85.7% | Reduced |
| Royal Bank of Canada | 320 | $5.00K | 0.00% | −3,924−92.5% | Reduced |
| Amalgamated Bank | 424 | $7.00K | 0.00% | −1,021−70.7% | Reduced |
| Ikarian Capital, LLC | 501 | $8.22K | 0.00% | −47,669−99.0% | Reduced |
| STRS Ohio | 700 | $11.0K | 0.00% | +700 | New |
| Federated Hermes, Inc. | 713 | $11.7K | 0.00% | −1,357−65.6% | Reduced |
| Metropolitan Life Insurance Co | 814 | $13.3K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 940 | $15.4K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 1,265 | $20.7K | 0.00% | 00.0% | Unchanged |
| EntryPoint Capital, LLC | 1,345 | $22.1K | 0.02% | +1,345 | New |
| California State Teachers Retirement System | 1,406 | $23.1K | 0.00% | −896−38.9% | Reduced |
| Wells Fargo & Company | 4,725 | $77.5K | 0.00% | +652+16.0% | Added |
| Deutsche Bank AG | 6,013 | $98.6K | 0.00% | −210−3.4% | Reduced |
| American International Group, Inc. | 6,892 | $113.0K | 0.00% | −59−0.8% | Reduced |
| Qube Research & Technologies Ltd | 7,032 | $115.3K | 0.00% | +4,379+165.1% | Added |
| Citigroup Inc | 7,106 | $116.5K | 0.00% | +5,075+249.9% | Added |
| MetLife Investment Management | 7,702 | $126.3K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 9,850 | $161.5K | 0.00% | −9,377−48.8% | Reduced |
| Baker Bros. Advisors LP | 10,607 | $174.0K | 0.00% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 10,750 | $176.3K | 0.00% | +141+1.3% | Added |
| PDT Partners, LLC | 12,174 | $199.7K | 0.02% | +12,174 | New |
| Hudson Bay Capital Management LP | 13,317 | $218.4K | 0.00% | +13,317 | New |
| Goldman Sachs Group Inc | 14,077 | $230.9K | 0.00% | +14,077 | New |
| UBS Group AG | 14,172 | $232.4K | 0.00% | +9,195+184.7% | Added |
| Fishman Jay A Ltd | 15,000 | $246.0K | 0.03% | +15,000 | New |
| Jump Financial, LLC | 15,159 | $248.6K | 0.01% | +15,159 | New |
| Exchange Traded Concepts, LLC | 16,053 | $263.3K | 0.01% | +6,522+68.4% | Added |
| Citadel Advisors LLC | 16,789 | $275.3K | 0.00% | +16,789 | New |
| Walleye Capital LLC | 16,887 | $276.9K | 0.00% | +16,887 | New |
| Marshall Wace, LLP | 19,643 | $322.1K | 0.00% | −10,358−34.5% | Reduced |
| Legato Capital Management LLC | 20,259 | $332.2K | 0.04% | +20,259 | New |
| Rhumbline Advisers | 20,998 | $344.4K | 0.00% | −334−1.6% | Reduced |
| American Century Companies Inc | 24,937 | $409.0K | 0.00% | +14,057+129.2% | Added |
| Nuveen Asset Management, LLC | 25,713 | $421.7K | 0.00% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 28,300 | $464.1K | 0.13% | +28,300 | New |
| New York State Common Retirement Fund | 32,149 | $527.2K | 0.00% | +28,118+697.5% | Added |
| Bank of America Corp | 33,032 | $541.7K | 0.00% | +10,914+49.3% | Added |
| Morgan Stanley | 35,237 | $577.9K | 0.00% | −431−1.2% | Reduced |
| Two Sigma Investments, LP | 41,742 | $684.6K | 0.00% | +41,742 | New |
| Bank of New York Mellon Corp | 43,735 | $717.3K | 0.00% | +1,790+4.3% | Added |
| Victory Capital Management Inc | 48,090 | $788.7K | 0.00% | −2,130−4.2% | Reduced |
| Renaissance Technologies LLC | 54,400 | $892.0K | 0.00% | +54,400 | New |
| Oppenheimer & Co Inc | 59,576 | $977.0K | 0.02% | +59,576 | New |
| Auour Investments LLC | 85,020 | $1.39M | 0.51% | 00.0% | Unchanged |
| Wellington Management Group LLP | 101,788 | $1.67M | 0.00% | −648−0.6% | Reduced |
| Charles Schwab Investment Management Inc | 152,212 | $2.50M | 0.00% | +41,675+37.7% | Added |
| Nicholas Investment Partners, LP | 152,968 | $2.51M | 0.26% | +152,968 | New |
| Northern Trust Corp | 156,472 | $2.57M | 0.00% | +4,222+2.8% | Added |
| Driehaus Capital Management LLC | 203,709 | $3.34M | 0.03% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 272,150 | $4.46M | 0.06% | +272,150 | New |
| State Street Corp | 292,234 | $4.79M | 0.00% | +26,880+10.1% | Added |
| JPMorgan Chase & Co | 380,597 | $6.24M | 0.00% | −21,109−5.3% | Reduced |
| First Turn Management, LLC | 381,210 | $6.25M | 0.94% | +381,210 | New |
| Geode Capital Management, LLC | 416,808 | $6.84M | 0.00% | +83,339+25.0% | Added |
| Kynam Capital Management, LP | 515,190 | $8.45M | 0.94% | +175,000+51.4% | Added |
| Sio Capital Management, LLC | 535,741 | $8.79M | 3.06% | +535,741 | New |
| Perceptive Advisors LLC | 669,159 | $11.0M | 0.19% | +309,159+85.9% | Added |
| OrbiMed Advisors LLC | 768,638 | $12.6M | 0.25% | +768,638 | New |
| Frazier Life Sciences Management, L.P. | 832,220 | $13.6M | 0.58% | −194,200−18.9% | Reduced |
| Vanguard Group Inc | 899,800 | $14.8M | 0.00% | +140,833+18.6% | Added |
| 5AM Venture Management, LLC | 939,298 | $15.4M | 3.45% | +384,319+69.2% | Added |
| BlackRock Inc. | 1,044,225 | $17.1M | 0.00% | +79,191+8.2% | Added |
| Fairmount Funds Management LLC | 1,393,329 | $22.9M | 2.49% | 00.0% | Unchanged |
| TCG Crossover Management, LLC | 1,989,103 | $32.6M | 2.58% | 00.0% | Unchanged |
| FMR LLC | 3,977,208 | $65.2M | 0.00% | +1,208,512+43.6% | Added |
| Nextech Invest AG | 4,055,861 | $66.5M | 10.54% | +1,537,279+61.0% | Added |
| Canaan Partners XI LLC | 4,409,991 | $72.3M | 79.77% | 00.0% | Unchanged |
| BVF Inc | 4,661,194 | $76.4M | 2.10% | +1,921,599+70.1% | Added |
| Boxer Capital, LLC | 6,448,359 | $105.8M | 5.22% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 10,416,609 | $170.8M | 2.17% | +3,180,155+43.9% | Added |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −137,014−100.0% | Sold out |
| Mariner, LLC | 0 | $0 | 0.00% | −22,164−100.0% | Sold out |
| Sepio Capital, LP | 0 | $0 | 0.00% | −10,625−100.0% | Sold out |
| LPL Financial LLC | 0 | $0 | 0.00% | −10,500−100.0% | Sold out |
| Artia Global Partners LP | 0 | $0 | 0.00% | −10,253−100.0% | Sold out |
| Acuta Capital Partners, LLC | 0 | $0 | 0.00% | −8,867−100.0% | Sold out |
| AJOVista, LLC | 0 | $0 | 0.00% | −4,235−100.0% | Sold out |