Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 305 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 285
- +10 vs. Q4 2025
- Shares held
- 73.6M
- +6.99M (+10.5%) vs. Q4 2025
- Total value
- $6.42B
- −$704.3M (−9.9%) vs. Q4 2025
- New holders
- 63
- 102 more added
- Sold out
- 53
- 89 more reduced
6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 305 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 43,872 | $3.82M | 0.00% | +41,457+1,716.6% | Added |
| Utah Retirement Systems | 42,177 | $3.67M | 0.04% | +42,177 | New |
| SEI Investments Co | 40,685 | $3.54M | 0.00% | +3,253+8.7% | Added |
| Exome Asset Management LLC | 40,581 | $3.53M | 2.08% | +40,581 | New |
| Hillsdale Investment Management Inc. | 40,300 | $3.50M | 0.10% | −2,000−4.7% | Reduced |
| TD Asset Management Inc | 38,778 | $3.37M | 0.00% | −16,272−29.6% | Reduced |
| State of Wisconsin Investment Board | 36,571 | $3.18M | 0.01% | +492+1.4% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 34,677 | $2.98M | 0.00% | −224−0.6% | Reduced |
| EFG International AG | 34,214 | $2.98M | 0.06% | +4,923+16.8% | Added |
| Wells Fargo & Company | 34,108 | $2.97M | 0.00% | −38,509−53.0% | Reduced |
| Aspiriant, LLC | 33,007 | $2.87M | 0.08% | +33,007 | New |
| Lazard Asset Management LLC | 32,888 | $2.86M | 0.00% | +7,317+28.6% | Added |
| D. E. Shaw & Co., Inc. | 32,652 | $2.84M | 0.00% | +1,296+4.1% | Added |
| Alyeska Investment Group, L.P. | 32,589 | $2.83M | 0.01% | +32,589 | New |
| Harbor Capital Advisors, Inc. | 30,353 | $2.64M | 0.21% | −10,543−25.8% | Reduced |
| Prudential Financial Inc | 30,190 | $2.63M | 0.00% | −22,955−43.2% | Reduced |
| Vanguard Global Advisers, LLC | 29,700 | $2.58M | 0.00% | +29,700 | New |
| Aquatic Capital Management LLC | 29,671 | $2.58M | 0.07% | +29,671 | New |
| STRS Ohio | 28,914 | $2.51M | 0.01% | +16,914+141.0% | Added |
| MetLife Investment Management | 28,889 | $2.51M | 0.01% | −285−1.0% | Reduced |
| PDT Partners, LLC | 27,232 | $2.37M | 0.14% | −32,204−54.2% | Reduced |
| Wedge Capital Management L L P | 24,535 | $2.13M | 0.04% | +5,288+27.5% | Added |
| Profund Advisors LLC | 22,787 | $1.98M | 0.07% | +1,741+8.3% | Added |
| Mutual of America Capital Management LLC | 22,529 | $1.96M | 0.02% | +22,529 | New |
| Creative Planning | 21,085 | $1.83M | 0.00% | −4,121−16.3% | Reduced |
| Liberty Mutual Group Asset Management Inc. | 20,514 | $1.78M | 0.14% | +20,514 | New |
| Victory Capital Management Inc | 20,504 | $1.78M | 0.00% | −24,877−54.8% | Reduced |
| Tudor Investment Corp Et Al | 19,646 | $1.71M | 0.01% | +19,646 | New |
| State of New Jersey Common Pension Fund D | 19,386 | $1.69M | 0.01% | +116+0.6% | Added |
| Dimensional Fund Advisors LP | 19,151 | $1.67M | 0.00% | −12,867−40.2% | Reduced |
| SG Americas Securities, LLC | 18,760 | $1.63M | 0.00% | +7,019+59.8% | Added |
| Advisors Asset Management, Inc. | 18,718 | $1.63M | 0.03% | +194+1.0% | Added |
| Captrust Financial Advisors | 18,147 | $1.58M | 0.00% | −178−1.0% | Reduced |
| ExodusPoint Capital Management, LP | 17,775 | $1.55M | 0.02% | −57,366−76.3% | Reduced |
| Handelsbanken Fonder AB | 17,521 | $1.52M | 0.01% | 00.0% | Unchanged |
| HighVista Strategies LLC | 16,796 | $1.46M | 0.40% | −26,071−60.8% | Reduced |
| Guggenheim Capital LLC | 16,554 | $1.44M | 0.01% | +4,153+33.5% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 15,598 | $1.36M | 0.00% | +3,163+25.4% | Added |
| Knights of Columbus Asset Advisors LLC | 15,589 | $1.36M | 0.08% | +5,275+51.1% | Added |
| Arizona State Retirement System | 15,581 | $1.36M | 0.01% | −181−1.1% | Reduced |
| State Board of Administration of Florida Retirement System | 14,650 | $1.27M | 0.00% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 14,594 | $1.27M | 0.01% | +411+2.9% | Added |
| HSBC Holdings PLC | 14,307 | $1.22M | 0.00% | +14,307 | New |
| Vanguard Investments Australia, Ltd. | 13,927 | $1.21M | 0.00% | +13,927 | New |
| Jasper Ridge Partners, L.P. | 13,845 | $1.20M | 0.03% | +8,206+145.5% | Added |
| Intech Investment Management LLC | 13,739 | $1.19M | 0.01% | −7,611−35.6% | Reduced |
| KLP Kapitalforvaltning AS | 12,500 | $1.09M | 0.00% | +500+4.2% | Added |
| Bridgefront Capital, LLC | 12,495 | $1.09M | 0.27% | +12,495 | New |
| Stifel Financial Corp | 12,339 | $1.07M | 0.00% | −908−6.9% | Reduced |
| Citigroup Inc | 12,336 | $1.07M | 0.00% | −384−3.0% | Reduced |
| China Universal Asset Management Co., Ltd. | 12,118 | $1.05M | 0.08% | +1,243+11.4% | Added |
| DnB Asset Management AS | 11,195 | $973.6K | 0.00% | +32+0.3% | Added |
| ProShare Advisors LLC | 10,720 | $932.3K | 0.00% | −1,902−15.1% | Reduced |
| Barclays PLC | 10,652 | $926.4K | 0.00% | −120,784−91.9% | Reduced |
| Entropy Technologies, LP | 10,318 | $897.4K | 0.04% | +7,826+314.0% | Added |
| Toth Financial Advisory Corp | 10,000 | $869.7K | 0.10% | 00.0% | Unchanged |
| Cannon Financial Strategists, Inc. | 10,000 | $869.7K | 0.11% | 00.0% | Unchanged |
| Marshall Wace, LLP | 9,628 | $837.3K | 0.00% | +9,628 | New |
| AlphaCentric Advisors LLC | 9,297 | $808.6K | 0.81% | +4,245+84.0% | Added |
| Los Angeles Capital Management LLC | 9,219 | $801.8K | 0.00% | −15,115−62.1% | Reduced |
| Hudson Bay Capital Management LP | 9,120 | $793.2K | 0.00% | +9,120 | New |
| HighTower Advisors, LLC | 9,058 | $787.8K | 0.00% | +9,058 | New |
| CenterBook Partners LP | 9,026 | $785.0K | 0.04% | +9,026 | New |
| Exchange Traded Concepts, LLC | 8,463 | $736.0K | 0.01% | +2,383+39.2% | Added |
| Prelude Capital Management, LLC | 8,372 | $728.1K | 0.06% | +8,372 | New |
| Tower Research Capital LLC (TRC) | 7,715 | $671.0K | 0.02% | +4,753+160.5% | Added |
| Virtus Investment Advisers, Inc. | 7,434 | $646.5K | 0.18% | +1,417+23.5% | Added |
| Teacher Retirement System of Texas | 7,330 | $637.5K | 0.00% | −1,029−12.3% | Reduced |
| The PNC Financial Services Group, Inc. | 6,938 | $603.4K | 0.00% | +2,279+48.9% | Added |
| IMC-Chicago, LLC | 6,697 | $582.4K | 0.01% | +6,697 | New |
| E Fund Management Co., Ltd. | 6,453 | $561.2K | 0.02% | +6,453 | New |
| LPL Financial LLC | 6,198 | $539.0K | 0.00% | +771+14.2% | Added |
| Texas Treasury Safekeeping Trust Co | 6,154 | $535.0K | 0.09% | +6,154 | New |
| Campbell & CO Investment Adviser LLC | 5,958 | $518.2K | 0.03% | +5,958 | New |
| Great West Life Assurance Co | 5,797 | $507.0K | 0.00% | 00.0% | Unchanged |
| Blueshift Asset Management, LLC | 5,787 | $503.3K | 0.15% | +2,906+100.9% | Added |
| Principal Financial Group Inc | 5,637 | $490.3K | 0.00% | −561−9.1% | Reduced |
| Public Employees Retirement Association of Colorado | 5,463 | $475.0K | 0.00% | 00.0% | Unchanged |
| Fifth Third Bancorp | 5,260 | $457.5K | 0.00% | +5,260 | New |
| Xponance, Inc. | 4,990 | $434.0K | 0.00% | +721+16.9% | Added |
| Gotham Asset Management, LLC | 4,848 | $421.6K | 0.00% | −3−0.1% | Reduced |
| Rockefeller Capital Management L.P. | 4,844 | $421.3K | 0.00% | −6,927−58.8% | Reduced |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 4,650 | $404.4K | 0.01% | +1,078+30.2% | Added |
| E. Ohman J:or Asset Management AB | 4,409 | $383.5K | 0.01% | −2,180−33.1% | Reduced |
| Inceptionr LLC | 4,379 | $380.8K | 0.09% | +4,379 | New |
| Ameritas Investment Partners, Inc. | 4,365 | $379.6K | 0.01% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 4,300 | $374.0K | 0.00% | +4,300 | New |
| Jones Financial Companies LLLP | 4,918 | $372.9K | 0.00% | +4,687+2,029.0% | Added |
| Man Group plc | 4,022 | $349.8K | 0.00% | −5,536−57.9% | Reduced |
| Amundi | 4,017 | $349.4K | 0.00% | +4,017 | New |
| Abel Hall, LLC | 4,015 | $349.2K | 0.07% | +1,875+87.6% | Added |
| Centiva Capital, LP | 4,000 | $347.9K | 0.02% | +4,000 | New |
| Fox Run Management, L.L.C. | 4,499 | $347.5K | 0.06% | +4,499 | New |
| Ensign Peak Advisors, Inc | 3,859 | $335.6K | 0.00% | 00.0% | Unchanged |
| Quantinno Capital Management LP | 3,851 | $334.9K | 0.00% | +20+0.5% | Added |
| Bank of Montreal | 3,801 | $330.6K | 0.00% | +3,801 | New |
| Brevan Howard Capital Management LP | 3,777 | $328.5K | 0.00% | +3,777 | New |
| Freestone Capital Holdings, LLC | 3,700 | $321.8K | 0.01% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 3,562 | $309.8K | 0.00% | +319+9.8% | Added |
| Swiss Life Asset Management Ltd | 3,341 | $290.6K | 0.00% | +688+25.9% | Added |