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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.57B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2022

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
90
−18 vs. Q1 2022
Shares held
45.9M
−2.88M (−5.9%) vs. Q1 2022
Total value
$190.8M
−$371.5M (−66.1%) vs. Q1 2022
New holders
18
23 more added
Sold out
36
31 more reduced

3 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 90 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 304 institutions
Value heldQ2 2022: $190.8M
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $484.7MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.48BQ4 2022: $1.81BQ1 2023: $1.09BQ2 2023: $1.09BQ3 2023: $1.57BQ4 2023: $3.09BQ1 2024: $2.98BQ2 2024: $2.86BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.22BQ3 2025: $7.32BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.57B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026304$8.57B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.32B
Q2 2025227$4.22B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.86B
Q1 2024167$2.98B
Q4 2023169$3.09B
Q3 2023144$1.57B
Q2 2023116$1.09B
Q1 2023126$1.09B
Q4 2022115$1.81B
Q3 2022101$1.48B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$484.7M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q1 2022.

Institutions holding RYTM in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Primecap Management Co6,364,094$26.4M0.02%+72,103+1.1%Added
NEA Management Company, LLC4,912,306$20.4M1.05%00.0%Unchanged
Ra Capital Management, L.P.4,871,067$20.2M0.54%00.0%Unchanged
Federated Hermes, Inc.4,395,600$18.2M0.05%−669,513−13.2%Reduced
Baker Bros. Advisors LP4,125,062$17.1M0.10%00.0%Unchanged
Goldman Sachs Group Inc3,160,386$13.1M0.00%−179,364−5.4%Reduced
Vanguard Group Inc2,149,726$8.92M0.00%−107,294−4.8%Reduced
Janus Henderson Group PLC2,080,077$8.63M0.01%−870,925−29.5%Reduced
Franklin Resources Inc1,779,465$7.38M0.00%+110.0%Added
Alkeon Capital Management LLC1,500,000$6.22M0.04%+1,500,000New
Rock Springs Capital Management LP1,403,298$5.82M0.17%+166,272+13.4%Added
BlackRock Inc.1,177,575$4.89M0.00%−2,106,530−64.1%Reduced
MPM Asset Management LLC909,258$3.77M1.59%00.0%Unchanged
Assenagon Asset Management S.A.689,720$2.86M0.01%−16,200−2.3%Reduced
FMR LLC556,994$2.31M0.00%+3,127+0.6%Added
Millennium Management LLC489,121$2.03M0.00%+128,529+35.6%Added
Morgan Stanley430,747$1.79M0.00%+175,255+68.6%Added
Geode Capital Management, LLC399,794$1.66M0.00%−341,095−46.0%Reduced
Jacobs Levy Equity Management, Inc378,714$1.57M0.01%+378,714New
Opaleye Management Inc.362,000$1.50M0.68%+362,000New
Samsara BioCapital, LLC345,293$1.43M0.38%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)291,005$1.21M0.03%00.0%Unchanged
Dimensional Fund Advisors LP253,241$1.05M0.00%+59,532+30.7%Added
State Street Corp251,059$1.04M0.00%−560,124−69.1%Reduced
Ergoteles LLC212,800$883.0K0.03%+212,800New
State of Wisconsin Investment Board207,701$862.0K0.00%+109,801+112.2%Added
Charles Schwab Investment Management Inc172,730$717.0K0.00%−125,595−42.1%Reduced
Citadel Advisors LLC168,058$698.0K0.00%−81,866−32.8%Reduced
Rice Hall James & Associates, LLC159,000$660.0K0.03%+22,479+16.5%Added
Caxton Associates LP151,213$628.0K0.08%+110,105+267.8%Added
Tudor Investment Corp Et Al125,416$520.0K0.02%+74,178+144.8%Added
Northern Trust Corp111,249$462.0K0.00%−305,638−73.3%Reduced
Cubist Systematic Strategies, LLC98,091$407.0K0.00%+98,091New
Wellington Management Group LLP85,565$355.0K0.00%−246−0.3%Reduced
Swiss National Bank83,300$346.0K0.00%00.0%Unchanged
SG Americas Securities, LLC80,064$332.0K0.00%−5,118−6.0%Reduced
Bell & Brown Wealth Advisors, LLC70,400$293.0K0.16%−47,000−40.0%Reduced
Susquehanna International Group, LLP64,261$267.0K0.00%+46,590+263.7%Added
Public Employees Retirement System of Ohio57,218$237.0K0.00%+57,218New
UBS Asset Management Americas Inc54,823$227.5K0.00%+25,392+86.3%Added
Hennion & Walsh Asset Management, Inc.52,519$218.0K0.01%−781−1.5%Reduced
Bank of America Corp49,112$203.0K0.00%+9,497+24.0%Added
Squarepoint Ops LLC44,164$183.0K0.00%+29,602+203.3%Added
Nuveen Asset Management, LLC41,205$171.0K0.00%−158,745−79.4%Reduced
Chicago Partners Investment Group LLC12,821$162.0K0.01%+423+3.4%Added
Cornercap Investment Counsel Inc36,663$152.0K0.03%+36,663New
D. E. Shaw & Co., Inc.36,492$151.0K0.00%−60,493−62.4%Reduced
California State Teachers Retirement System31,946$133.0K0.00%−16,705−34.3%Reduced
Ensign Peak Advisors, Inc29,345$122.0K0.00%+24,255+476.5%Added
Bailard, Inc.29,500$122.0K0.00%+29,500New
Qube Research & Technologies Ltd28,794$119.0K0.00%+28,794New
ACT Capital Management, LLC27,500$114.0K0.16%00.0%Unchanged
Simplex Trading, LLC25,890$107.0K0.00%+21,991+564.0%Added
Credit Suisse AG24,522$102.0K0.00%−2,749−10.1%Reduced
Gsa Capital Partners LLP23,147$96.0K0.01%+23,147New
Virtu Financial LLC22,666$94.0K0.01%+22,666New
Hantz Financial Services, Inc.22,286$92.0K0.00%+2,399+12.1%Added
Bank of New York Mellon Corp21,495$89.0K0.00%−130,854−85.9%Reduced
BNP Paribas Arbitrage, SA20,586$85.4K0.00%+8,822+75.0%Added
Fiduciary Trust Co20,000$83.0K0.00%+20,000New
Stifel Financial Corp18,961$79.0K0.00%−7,405−28.1%Reduced
Ameriprise Financial Inc18,140$75.0K0.00%+18,140New
Laurion Capital Management LP16,322$68.0K0.00%+16,322New
LMR Partners LLP15,713$65.0K0.00%+15,713New
Legal & General Group Plc12,247$51.0K0.00%−1,016−7.7%Reduced
Connor, Clark & Lunn Investment Management Ltd.11,225$47.0K0.00%+11,225New
AQR Capital Management LLC10,295$43.0K0.00%+164+1.6%Added
Arizona State Retirement System10,230$42.0K0.00%+10,230New
Barclays PLC9,290$39.0K0.00%−11,909−56.2%Reduced
Wells Fargo & Company8,928$37.0K0.00%−890−9.1%Reduced
Macquarie Group Ltd8,155$34.0K0.00%00.0%Unchanged
UBS Group AG7,507$31.0K0.00%+7,007+1,401.4%Added
Tower Research Capital LLC (TRC)5,804$25.0K0.00%−28,704−83.2%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)3,742$16.0K0.00%00.0%Unchanged
Great West Life Assurance Co2,363$10.0K0.00%00.0%Unchanged
Sierra Capital LLC2,400$10.0K0.00%00.0%Unchanged
Aquatic Capital Management LLC2,300$10.0K0.00%+2,000+666.7%Added
Citigroup Inc2,266$9.00K0.00%−2,266−50.0%Reduced
FourThought Financial, LLC1,776$7.00K0.00%00.0%Unchanged
Cutler Group LP1,336$5.00K0.00%−500−27.2%Reduced
JPMorgan Chase & Co441$2.00K0.00%−26,540−98.4%Reduced
New York State Common Retirement Fund314$1.00K0.00%−30,268−99.0%Reduced
The PNC Financial Services Group, Inc.350$1.00K0.00%00.0%Unchanged
CWM, LLC200$1.00K0.00%−66−24.8%Reduced
Daiwa Securities Group Inc.172$1.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.210$1.00K0.00%00.0%Unchanged
Private Capital Group, LLC264$1.00K0.00%+264New
Exane Derivatives10$410.00%−10,223−99.9%Reduced
Newbridge Financial Services Group, Inc.65$00.00%00.0%Unchanged
Beaird Harris Wealth Management, LLC49$00.00%00.0%Unchanged
Deutsche Bank AG0$00.00%−227,114−100.0%Sold out
Pinz Capital Management, LP0$00.00%−148,475−100.0%Sold out
Endurant Capital Management LP0$00.00%−105,792−100.0%Sold out
Rhumbline Advisers0$00.00%−56,942−100.0%Sold out
HRT Financial LP0$00.00%−49,198−100.0%Sold out
Alliancebernstein L.P.0$00.00%−44,900−100.0%Sold out
Jump Financial, LLC0$00.00%−27,500−100.0%Sold out
MetLife Investment Management0$00.00%−24,442−100.0%Sold out
Nisa Investment Advisors, LLC0$00.00%−23,400−100.0%Sold out
Renaissance Technologies LLC0$00.00%−23,100−100.0%Sold out