Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.57B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 115
- +14 vs. Q3 2022
- Shares held
- 62.3M
- +2.82M (+4.7%) vs. Q3 2022
- Total value
- $1.81B
- +$369.1M (+25.5%) vs. Q3 2022
- New holders
- 26
- 42 more added
- Sold out
- 12
- 28 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.57B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.32B |
| Q2 2025 | 227 | $4.22B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.86B |
| Q1 2024 | 167 | $2.98B |
| Q4 2023 | 169 | $3.09B |
| Q3 2023 | 144 | $1.57B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.09B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.48B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $484.7M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Primecap Management Co | 6,911,142 | $201.3M | 0.18% | −115,750−1.6% | Reduced |
| Baker Bros. Advisors LP | 6,354,608 | $185.0M | 1.11% | +291,906+4.8% | Added |
| Federated Hermes, Inc. | 6,304,482 | $183.6M | 0.51% | −2,3840.0% | Reduced |
| Ra Capital Management, L.P. | 5,516,067 | $160.6M | 3.26% | +45,000+0.8% | Added |
| Goldman Sachs Group Inc | 5,201,792 | $151.5M | 0.04% | +424,614+8.9% | Added |
| NEA Management Company, LLC | 4,909,956 | $143.0M | 8.03% | −2,3500.0% | Reduced |
| BlackRock Inc. | 3,723,714 | $108.4M | 0.00% | +186,215+5.3% | Added |
| State Street Corp | 3,180,698 | $92.6M | 0.01% | +52,793+1.7% | Added |
| Vanguard Group Inc | 2,596,314 | $75.6M | 0.00% | +362,042+16.2% | Added |
| Alkeon Capital Management LLC | 2,238,262 | $65.2M | 0.48% | +533,262+31.3% | Added |
| Frazier Life Sciences Management, L.P. | 1,894,000 | $55.2M | 3.43% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 1,760,865 | $51.3M | 1.23% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 1,250,000 | $36.4M | 0.29% | +535,261+74.9% | Added |
| Janus Henderson Group PLC | 1,240,153 | $36.1M | 0.03% | −320,930−20.6% | Reduced |
| FMR LLC | 773,028 | $22.5M | 0.00% | −597,920−43.6% | Reduced |
| Opaleye Management Inc. | 735,000 | $21.4M | 7.44% | −75,000−9.3% | Reduced |
| Susquehanna International Group, LLP | 694,042 | $20.2M | 0.04% | +479,520+223.5% | Added |
| Assenagon Asset Management S.A. | 463,516 | $13.5M | 0.06% | −6,894−1.5% | Reduced |
| Geode Capital Management, LLC | 458,510 | $13.4M | 0.00% | +70,398+18.1% | Added |
| D. E. Shaw & Co., Inc. | 355,530 | $10.4M | 0.02% | +172,461+94.2% | Added |
| Samsara BioCapital, LLC | 345,293 | $10.1M | 2.17% | 00.0% | Unchanged |
| Invesco Ltd. | 334,273 | $9.73M | 0.00% | +334,273 | New |
| Rafferty Asset Management, LLC | 306,013 | $8.91M | 0.07% | +43,725+16.7% | Added |
| Citigroup Inc | 275,561 | $8.02M | 0.01% | +3,374+1.2% | Added |
| Bank of America Corp | 266,153 | $7.75M | 0.00% | +47,744+21.9% | Added |
| Morgan Stanley | 243,685 | $7.10M | 0.00% | +13,488+5.9% | Added |
| Charles Schwab Investment Management Inc | 229,916 | $6.70M | 0.00% | +25,647+12.6% | Added |
| Jane Street Group, LLC | 199,503 | $5.81M | 0.01% | +199,503 | New |
| Voloridge Investment Management, LLC | 194,996 | $5.68M | 0.03% | −48,412−19.9% | Reduced |
| UBS Group AG | 191,265 | $5.57M | 0.00% | +178,630+1,413.8% | Added |
| Barclays PLC | 182,599 | $5.32M | 0.00% | +18,246+11.1% | Added |
| Qube Research & Technologies Ltd | 180,557 | $5.26M | 0.03% | +180,557 | New |
| Altium Capital Management LP | 170,000 | $4.95M | 2.53% | 00.0% | Unchanged |
| EAM Investors, LLC | 164,695 | $4.80M | 0.99% | −34,004−17.1% | Reduced |
| Parkman Healthcare Partners LLC | 157,862 | $4.60M | 1.22% | −30,127−16.0% | Reduced |
| Rice Hall James & Associates, LLC | 153,202 | $4.46M | 0.26% | −17,155−10.1% | Reduced |
| Northern Trust Corp | 138,101 | $4.02M | 0.00% | +23,992+21.0% | Added |
| Dimensional Fund Advisors LP | 136,991 | $3.99M | 0.00% | −86,140−38.6% | Reduced |
| Schonfeld Strategic Advisors LLC | 120,689 | $3.51M | 0.03% | +71,786+146.8% | Added |
| Ensign Peak Advisors, Inc | 108,562 | $3.16M | 0.01% | +97,392+871.9% | Added |
| Wellington Management Group LLP | 106,916 | $3.11M | 0.00% | −46,297−30.2% | Reduced |
| Swiss National Bank | 97,900 | $2.85M | 0.00% | +8,300+9.3% | Added |
| Stratos Wealth Partners, LTD. | 73,320 | $2.14M | 0.05% | +34,705+89.9% | Added |
| Citadel Advisors LLC | 70,698 | $2.06M | 0.00% | +14,863+26.6% | Added |
| Squarepoint Ops LLC | 65,138 | $1.90M | 0.01% | +7,144+12.3% | Added |
| Voya Investment Management LLC | 63,595 | $1.85M | 0.00% | 00.0% | Unchanged |
| EAM Global Investors LLC | 62,623 | $1.82M | 0.47% | −16,353−20.7% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 59,298 | $1.73M | 0.11% | +7,496+14.5% | Added |
| BNP Paribas Arbitrage, SA | 52,884 | $1.54M | 0.00% | −28,049−34.7% | Reduced |
| Nuveen Asset Management, LLC | 47,491 | $1.38M | 0.00% | +7,201+17.9% | Added |
| Credit Suisse AG | 47,412 | $1.38M | 0.00% | +11,928+33.6% | Added |
| Millennium Management LLC | 42,298 | $1.23M | 0.00% | +42,298 | New |
| UBS Asset Management Americas Inc | 42,197 | $1.23M | 0.00% | +12,260+41.0% | Added |
| Bell & Brown Wealth Advisors, LLC | 41,600 | $1.21M | 0.67% | +41,600 | New |
| State of Wisconsin Investment Board | 40,758 | $1.19M | 0.00% | +2,253+5.9% | Added |
| Alps Advisors Inc | 38,198 | $1.11M | 0.01% | +38,198 | New |
| HighVista Strategies LLC | 35,478 | $1.03M | 0.61% | +35,478 | New |
| California State Teachers Retirement System | 35,306 | $1.03M | 0.00% | +2,786+8.6% | Added |
| Jupiter Asset Management Ltd | 33,360 | $969.1K | 0.01% | +33,360 | New |
| Nan Fung Group Holdings Ltd | 32,520 | $947.0K | 0.65% | +32,520 | New |
| Candriam Luxembourg S.C.A. | 32,479 | $945.7K | 0.01% | −5,755−15.1% | Reduced |
| Bank of New York Mellon Corp | 32,283 | $940.1K | 0.00% | −7,625−19.1% | Reduced |
| DekaBank Deutsche Girozentrale | 30,000 | $890.0K | 0.00% | 00.0% | Unchanged |
| Landscape Capital Management, L.L.C. | 27,132 | $790.1K | 0.12% | +27,132 | New |
| LMR Partners LLP | 25,044 | $729.3K | 0.02% | +9,331+59.4% | Added |
| Driehaus Capital Management LLC | 22,993 | $669.6K | 0.01% | 00.0% | Unchanged |
| Marshall Wace, LLP | 21,283 | $619.8K | 0.00% | +21,283 | New |
| Fiduciary Trust Co | 20,000 | $582.4K | 0.01% | −10,000−33.3% | Reduced |
| Fred Alger Management, LLC | 19,988 | $582.1K | 0.00% | −298−1.5% | Reduced |
| JPMorgan Chase & Co | 19,641 | $572.0K | 0.00% | +17,430+788.3% | Added |
| Campbell & CO Investment Adviser LLC | 19,535 | $568.9K | 0.14% | +19,535 | New |
| Stifel Financial Corp | 19,380 | $564.3K | 0.00% | −200−1.0% | Reduced |
| Ameriprise Financial Inc | 18,140 | $528.0K | 0.00% | 00.0% | Unchanged |
| Parkwood LLC | 17,546 | $511.0K | 0.10% | +17,546 | New |
| ClariVest Asset Management LLC | 16,500 | $481.0K | 0.02% | −300−1.8% | Reduced |
| Cubist Systematic Strategies, LLC | 16,508 | $480.7K | 0.00% | −95,003−85.2% | Reduced |
| E Fund Management Co., Ltd. | 16,056 | $468.0K | 0.04% | −1,979−11.0% | Reduced |
| SEI Investments Co | 15,453 | $450.0K | 0.00% | −3,805−19.8% | Reduced |
| Legal & General Group Plc | 14,796 | $430.9K | 0.00% | +5,028+51.5% | Added |
| Price T Rowe Associates Inc | 14,200 | $414.0K | 0.00% | −2,100−12.9% | Reduced |
| Tower Research Capital LLC (TRC) | 13,750 | $400.0K | 0.02% | +5,276+62.3% | Added |
| Teacher Retirement System of Texas | 12,034 | $350.0K | 0.00% | −335−2.7% | Reduced |
| Allianz Asset Management GmbH | 11,900 | $346.5K | 0.00% | 00.0% | Unchanged |
| Mirabella Financial Services LLP | 11,489 | $334.6K | 0.03% | +11,489 | New |
| Arizona State Retirement System | 11,449 | $333.4K | 0.00% | +1,178+11.5% | Added |
| Virtus ETF Advisers LLC | 10,221 | $297.6K | 0.16% | +10,221 | New |
| American Century Companies Inc | 9,041 | $263.3K | 0.00% | +9,041 | New |
| Virginia Retirement Systems Et Al | 8,000 | $233.0K | 0.00% | +8,000 | New |
| Gsa Capital Partners LLP | 7,451 | $217.0K | 0.03% | −1,641−18.0% | Reduced |
| 683 Capital Management, LLC | 6,960 | $202.7K | 0.02% | +6,960 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 6,879 | $200.3K | 0.00% | +691+11.2% | Added |
| Wells Fargo & Company | 6,743 | $196.4K | 0.00% | +4,569+210.2% | Added |
| Deutsche Bank AG | 5,646 | $164.4K | 0.00% | +5,646 | New |
| Simplex Trading, LLC | 5,581 | $162.0K | 0.01% | +5,581 | New |
| Farther Finance Advisors, LLC | 3,812 | $111.0K | 0.04% | +3,812 | New |
| Denali Advisors LLC | 3,200 | $93.2K | 0.04% | +1,300+68.4% | Added |
| Sierra Capital LLC | 2,400 | $70.0K | 0.01% | 00.0% | Unchanged |
| Great West Life Assurance Co | 2,363 | $69.0K | 0.00% | 00.0% | Unchanged |
| State of Wyoming | 2,228 | $64.9K | 0.02% | +2,228 | New |
| New York State Common Retirement Fund | 1,072 | $31.2K | 0.00% | 00.0% | Unchanged |