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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q4 2022

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
115
+14 vs. Q3 2022
Shares held
62.3M
+2.82M (+4.7%) vs. Q3 2022
Total value
$1.81B
+$369.1M (+25.5%) vs. Q3 2022
New holders
26
42 more added
Sold out
12
28 more reduced

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 115 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 304 institutions
Value heldQ4 2022: $1.81B
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026304$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q3 2022.

Institutions holding RYTM in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
NewSquare Capital LLC20$5820.00%+20New
US Bancorp45$1.31K0.00%00.0%Unchanged
Beaird Harris Wealth Management, LLC49$1.43K0.00%00.0%Unchanged
Newbridge Financial Services Group, Inc.65$1.89K0.00%00.0%Unchanged
Vigilant Capital Management, LLC100$3.00K0.00%+100New
Harbour Investments, Inc.148$4.31K0.00%+148New
Royal Bank of Canada174$5.00K0.00%+109+167.7%Added
Signaturefd, LLC204$5.94K0.00%00.0%Unchanged
CWM, LLC200$6.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.209$6.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.227$7.00K0.00%+55+32.0%Added
Focused Wealth Management, Inc300$8.74K0.00%−1,700−85.0%Reduced
The PNC Financial Services Group, Inc.350$10.2K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.572$16.7K0.01%+97+20.4%Added
Balyasny Asset Management LLC766$22.3K0.00%+766New
New York State Common Retirement Fund1,072$31.2K0.00%00.0%Unchanged
State of Wyoming2,228$64.9K0.02%+2,228New
Great West Life Assurance Co2,363$69.0K0.00%00.0%Unchanged
Sierra Capital LLC2,400$70.0K0.01%00.0%Unchanged
Denali Advisors LLC3,200$93.2K0.04%+1,300+68.4%Added
Farther Finance Advisors, LLC3,812$111.0K0.04%+3,812New
Simplex Trading, LLC5,581$162.0K0.01%+5,581New
Deutsche Bank AG5,646$164.4K0.00%+5,646New
Wells Fargo & Company6,743$196.4K0.00%+4,569+210.2%Added
Zurcher Kantonalbank (Zurich Cantonalbank)6,879$200.3K0.00%+691+11.2%Added
683 Capital Management, LLC6,960$202.7K0.02%+6,960New
Gsa Capital Partners LLP7,451$217.0K0.03%−1,641−18.0%Reduced
Virginia Retirement Systems Et Al8,000$233.0K0.00%+8,000New
American Century Companies Inc9,041$263.3K0.00%+9,041New
Virtus ETF Advisers LLC10,221$297.6K0.16%+10,221New
Arizona State Retirement System11,449$333.4K0.00%+1,178+11.5%Added
Mirabella Financial Services LLP11,489$334.6K0.03%+11,489New
Allianz Asset Management GmbH11,900$346.5K0.00%00.0%Unchanged
Teacher Retirement System of Texas12,034$350.0K0.00%−335−2.7%Reduced
Tower Research Capital LLC (TRC)13,750$400.0K0.02%+5,276+62.3%Added
Price T Rowe Associates Inc14,200$414.0K0.00%−2,100−12.9%Reduced
Legal & General Group Plc14,796$430.9K0.00%+5,028+51.5%Added
SEI Investments Co15,453$450.0K0.00%−3,805−19.8%Reduced
E Fund Management Co., Ltd.16,056$468.0K0.04%−1,979−11.0%Reduced
Cubist Systematic Strategies, LLC16,508$480.7K0.00%−95,003−85.2%Reduced
ClariVest Asset Management LLC16,500$481.0K0.02%−300−1.8%Reduced
Parkwood LLC17,546$511.0K0.10%+17,546New
Ameriprise Financial Inc18,140$528.0K0.00%00.0%Unchanged
Stifel Financial Corp19,380$564.3K0.00%−200−1.0%Reduced
Campbell & CO Investment Adviser LLC19,535$568.9K0.14%+19,535New
JPMorgan Chase & Co19,641$572.0K0.00%+17,430+788.3%Added
Fred Alger Management, LLC19,988$582.1K0.00%−298−1.5%Reduced
Fiduciary Trust Co20,000$582.4K0.01%−10,000−33.3%Reduced
Marshall Wace, LLP21,283$619.8K0.00%+21,283New
Driehaus Capital Management LLC22,993$669.6K0.01%00.0%Unchanged
LMR Partners LLP25,044$729.3K0.02%+9,331+59.4%Added
Landscape Capital Management, L.L.C.27,132$790.1K0.12%+27,132New
DekaBank Deutsche Girozentrale30,000$890.0K0.00%00.0%Unchanged
Bank of New York Mellon Corp32,283$940.1K0.00%−7,625−19.1%Reduced
Candriam Luxembourg S.C.A.32,479$945.7K0.01%−5,755−15.1%Reduced
Nan Fung Group Holdings Ltd32,520$947.0K0.65%+32,520New
Jupiter Asset Management Ltd33,360$969.1K0.01%+33,360New
California State Teachers Retirement System35,306$1.03M0.00%+2,786+8.6%Added
HighVista Strategies LLC35,478$1.03M0.61%+35,478New
Alps Advisors Inc38,198$1.11M0.01%+38,198New
State of Wisconsin Investment Board40,758$1.19M0.00%+2,253+5.9%Added
Bell & Brown Wealth Advisors, LLC41,600$1.21M0.67%+41,600New
UBS Asset Management Americas Inc42,197$1.23M0.00%+12,260+41.0%Added
Millennium Management LLC42,298$1.23M0.00%+42,298New
Credit Suisse AG47,412$1.38M0.00%+11,928+33.6%Added
Nuveen Asset Management, LLC47,491$1.38M0.00%+7,201+17.9%Added
BNP Paribas Arbitrage, SA52,884$1.54M0.00%−28,049−34.7%Reduced
Hennion & Walsh Asset Management, Inc.59,298$1.73M0.11%+7,496+14.5%Added
EAM Global Investors LLC62,623$1.82M0.47%−16,353−20.7%Reduced
Voya Investment Management LLC63,595$1.85M0.00%00.0%Unchanged
Squarepoint Ops LLC65,138$1.90M0.01%+7,144+12.3%Added
Citadel Advisors LLC70,698$2.06M0.00%+14,863+26.6%Added
Stratos Wealth Partners, LTD.73,320$2.14M0.05%+34,705+89.9%Added
Swiss National Bank97,900$2.85M0.00%+8,300+9.3%Added
Wellington Management Group LLP106,916$3.11M0.00%−46,297−30.2%Reduced
Ensign Peak Advisors, Inc108,562$3.16M0.01%+97,392+871.9%Added
Schonfeld Strategic Advisors LLC120,689$3.51M0.03%+71,786+146.8%Added
Dimensional Fund Advisors LP136,991$3.99M0.00%−86,140−38.6%Reduced
Northern Trust Corp138,101$4.02M0.00%+23,992+21.0%Added
Rice Hall James & Associates, LLC153,202$4.46M0.26%−17,155−10.1%Reduced
Parkman Healthcare Partners LLC157,862$4.60M1.22%−30,127−16.0%Reduced
EAM Investors, LLC164,695$4.80M0.99%−34,004−17.1%Reduced
Altium Capital Management LP170,000$4.95M2.53%00.0%Unchanged
Qube Research & Technologies Ltd180,557$5.26M0.03%+180,557New
Barclays PLC182,599$5.32M0.00%+18,246+11.1%Added
UBS Group AG191,265$5.57M0.00%+178,630+1,413.8%Added
Voloridge Investment Management, LLC194,996$5.68M0.03%−48,412−19.9%Reduced
Jane Street Group, LLC199,503$5.81M0.01%+199,503New
Charles Schwab Investment Management Inc229,916$6.70M0.00%+25,647+12.6%Added
Morgan Stanley243,685$7.10M0.00%+13,488+5.9%Added
Bank of America Corp266,153$7.75M0.00%+47,744+21.9%Added
Citigroup Inc275,561$8.02M0.01%+3,374+1.2%Added
Rafferty Asset Management, LLC306,013$8.91M0.07%+43,725+16.7%Added
Invesco Ltd.334,273$9.73M0.00%+334,273New
Samsara BioCapital, LLC345,293$10.1M2.17%00.0%Unchanged
D. E. Shaw & Co., Inc.355,530$10.4M0.02%+172,461+94.2%Added
Geode Capital Management, LLC458,510$13.4M0.00%+70,398+18.1%Added
Assenagon Asset Management S.A.463,516$13.5M0.06%−6,894−1.5%Reduced
Susquehanna International Group, LLP694,042$20.2M0.04%+479,520+223.5%Added
Opaleye Management Inc.735,000$21.4M7.44%−75,000−9.3%Reduced